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81. 发明申请

US20130261741A1 Prosthetic Heart Valves and Devices, Systems and Methods for Prosthetic Heart Valves 审中-公开
标题翻译：假神经心脏瓣膜和装置，假体心脏瓣膜的系统和方法
公开(公告)号：US20130261741A1
公开(公告)日：2013-10-03
申请号：US13811451
申请日：2011-07-21
申请人： Kevin D. Accola
发明人： Kevin D. Accola
IPC分类号： A61F2/24
CPC分类号： A61F2/24 , A61B17/1204 , A61B17/12136 , A61F2/2403 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/243
摘要： Described herein is a unique sutureless heart valve that includes a deployment mechanism having a plurality of fasteners. The plurality of fasteners may be actuated at least two states: a disengaged state wherein said plurality of fasteners are retracted, and an engaged state wherein said plurality of fasteners are extended; and further comprising a deployed state wherein said plurality of fasteners, when extended, are irreversibly locked such that said heart valve is securely deployed at the target surgical site. The valve deployment mechanism comprises a ring assembly comprising a first annular member onto which said plurality of fasteners are associated and a second annular member peripheral to said first annular member and comprising a series of windows through which individual fasteners of said plurality of fasteners project.
摘要翻译：这里描述的是独特的无缝心脏瓣膜，其包括具有多个紧固件的展开机构。多个紧固件可以致动至少两种状态：其中所述多个紧固件缩回的脱离状态以及所述多个紧固件被延伸的接合状态; 并且还包括展开状态，其中当延伸时所述多个紧固件不可逆地锁定，使得所述心脏瓣膜被牢固地部署在目标手术部位。所述阀布置机构包括环组件，所述环组件包括第一环形构件，所述多个紧固件与所述第一环形构件相关联;以及第二环形构件，所述第二环形构件围绕所述第一环形构件并包括一系列窗户，所述多个紧固件中的各个紧固件通过

82. 发明申请

US20130253342A1 PASS-THROUGH IMPLANTABLE MEDICAL DEVICE DELIVERY CATHETER 审中-公开
标题翻译： PASS-THROUGH医疗器械输送管
公开(公告)号：US20130253342A1
公开(公告)日：2013-09-26
申请号：US13482684
申请日：2012-05-29
申请人： Erik C. Griswold , James Calvin Allan , Don H. Tran
发明人： Erik C. Griswold , James Calvin Allan , Don H. Tran
IPC分类号： A61M25/14 , A61B5/0215 , A61B5/00 , A61M25/02 , A61M25/00 , A61B19/00
CPC分类号： A61N1/3627 , A61B5/0215 , A61B5/046 , A61B5/0464 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61N1/057 , A61N1/059 , A61N1/365 , A61N1/36585 , A61N1/37288 , A61N1/3756 , A61N2001/0578 , A61N2001/0585
摘要： In one example, this disclosure is directed to a kit for intravascular implantation of an implantable medical device within a patient, the kit comprising an elongated inner sheath with a distal end, a first coupling module slidably connected to the inner sheath, an elongated outer sheath forming an inner lumen with a distal opening and a proximal opening. The outer sheath sized to traverse a vasculature of the patient. The proximal opening is configured to receive the distal end of the inner sheath. The inner lumen is sized to receive the inner sheath and to contain the implantable medical device. The kit further includes a mating coupling module that connects to the first coupling module such that the inner sheath is axially aligned with the outer sheath. The inner sheath is slidable within the outer sheath while the first coupling module is connected to the mating coupling module.
摘要翻译：在一个示例中，本公开涉及用于患者内的可植入医疗装置的血管内植入的套件，所述套件包括具有远端的细长内护套，可滑动地连接到内护套的第一联接模块，细长外护套形成具有远端开口和近端开口的内腔。外护套的尺寸适于穿过患者的脉管系统。近端开口被构造成接纳内护套的远端。内腔的尺寸设置成接收内护套并容纳可植入的医疗装置。套件还包括配合联接模块，其连接到第一联接模块，使得内护套与外护套轴向对准。内护套可在外护套内滑动，而第一联接模块连接到配合联接模块。

83. 发明申请

US20130245608A1 IMPLANTABLE DEVICES AND METHODS FOR TREATING SINUSITIS AND OTHER DISORDERS 审中-公开
标题翻译：可治疗装置和治疗神经病和其他疾病的方法
公开(公告)号：US20130245608A1
公开(公告)日：2013-09-19
申请号：US13784293
申请日：2013-03-04
申请人： Ketan P. Muni , Hung V. Ha , John H. Morriss , William E. Bolger , Joshua Makower , John Y. Chang , Randy S. Chan , Nga K. Van , Anton G. Clifford
发明人： Ketan P. Muni , Hung V. Ha , John H. Morriss , William E. Bolger , Joshua Makower , John Y. Chang , Randy S. Chan , Nga K. Van , Anton G. Clifford
IPC分类号： A61M29/02
CPC分类号： A61M29/02 , A61B17/1204 , A61B17/12104 , A61B17/12136 , A61B17/24 , A61B17/3417 , A61B17/3421 , A61B17/3478 , A61F11/004 , A61M25/0075 , A61M25/0084 , A61M25/04 , A61M25/10 , A61M2025/105 , A61M2025/1052 , A61M2025/1086 , A61M2210/0618
摘要： Devices, systems and methods for stenting, spacing, draining, ventilating and/or delivering drugs and other therapeutic or diagnostic substances to desired locations within the bodies of human or non-human animal subjects, including methods and systems for treating paranasal sinusitis and ethmoid disease.
摘要翻译：用于支架，间隔，排泄，通气和/或递送药物和其他治疗或诊断物质到人或非人类动物受试者体内所需位置的装置，系统和方法，包括用于治疗鼻旁窦炎和筛窦疾病的方法和系统。

84. 发明授权

US08500623B2 Method and device for intermittent occlusion of a vein draining the organ system 有权
公开(公告)号：US08500623B2
公开(公告)日：2013-08-06
申请号：US13437325
申请日：2012-04-02
申请人： Werner Mohl
发明人： Werner Mohl
IPC分类号： A61M1/10
CPC分类号： A61B17/12022 , A61B5/02152 , A61B17/12 , A61B17/1204 , A61B17/12136 , A61B2017/00557 , A61M1/106 , A61M1/1072 , A61M1/1086 , A61M1/125 , A61M1/3613 , A61M25/10181 , A61M2025/0002 , A61M2025/1052 , A61M2205/3344
摘要： In a method for the intermittent occlusion of a vein draining the organ system, in which the vein is occluded by an occlusion device, the fluid pressure in the occluded vein is continuously measured and stored, the behavior of the fluid pressure is determined as a function of time, and the occlusion of the vein is triggered and/or released as a function of at least one characteristic value derived from the pressure measurements, pressure is applied during the occlusion in a pulsating manner. The device for the intermittent occlusion of a vein, including an occlusion device, a pressure measuring device for continuously measuring the fluid pressure in the occluded vein, and a memory for storing the fluid pressure behavior as a function of time, means are provided for applying a pulsating pressure in the occluded vein.

85. 发明申请

US20130197483A1 GUIDE EXTENSION CATHETER 有权
公开(公告)号：US20130197483A1
公开(公告)日：2013-08-01
申请号：US13755989
申请日：2013-01-31
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： JAMES M. ANDERSON , HUISUN WANG , DEREK C. SUTERMEISTER , STEVEN J. KOCH , BENJAMIN P. GUNDALE , PAUL J. MILLER
IPC分类号： A61M25/01 , A61M25/00
CPC分类号： A61M25/0662 , A61B17/1204 , A61B17/12136 , A61B2017/00526 , A61M25/0009 , A61M25/0052 , A61M25/0069 , A61M25/01 , A61M25/0105 , A61M25/04 , A61M2025/0681 , F04C2270/0421
摘要： Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a push member having a proximal portion with a proximal stiffness, a distal portion with a distal stiffness different from the proximal stiffness, and a transition portion disposed between the proximal portion and the distal portion. The transition portion may provide a smooth transition between the proximal stiffness and the distal stiffness. The push member may have a first outer diameter. A distal tubular member may be attached to the push member. The distal tubular member may have a second outer diameter larger than the first outer diameter.

86. 发明授权

US08491623B2 Atraumatic occlusion balloons and skirts, and methods of use thereof 有权
标题翻译：无创伤闭塞气球和裙子及其使用方法
公开(公告)号：US08491623B2
公开(公告)日：2013-07-23
申请号：US11851848
申请日：2007-09-07
申请人： Jean-Marie Vogel , William E. Cohn
发明人： Jean-Marie Vogel , William E. Cohn
IPC分类号： A61M29/00
CPC分类号： A61B17/12195 , A61B17/08 , A61B17/12031 , A61B17/1204 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/12186 , A61B2017/1205 , A61M29/02 , A61M2025/1052
摘要： One aspect of the present invention relates to catheters that can be placed in or around bodily conduits to occlude or widen a biological lumen without imparting significant trauma to the lumen. In certain embodiments, the invention particularly relates to the use of a polymer composition which can be made to gel upon insertion into said balloon or skirt. In certain embodiments, the inflating viscous polymer composition is a liquid at room temperature and a gel at mammalian physiological temperature. In certain embodiments, the inflating viscous polymer composition comprises an optionally purified inverse thermosensitive polymer.
摘要翻译：本发明的一个方面涉及可以放置在身体管道中或周围的导管，以封闭或加宽生物腔，而不会对内腔产生显着的创伤。在某些实施方案中，本发明特别涉及聚合物组合物的用途，所述聚合物组合物可以在插入所述气囊或裙部时使其凝胶化。在某些实施方案中，充气粘性聚合物组合物在室温下为液体，在哺乳动物生理温度下为凝胶。在某些实施方案中，充气粘性聚合物组合物包含任选纯化的反相热敏聚合物。

87. 发明申请

US20130172923A1 FLEXIBLE LOW COMPLIANCE EXTENSION TUBING FOR BALLOON INFLATION 审中-公开
标题翻译：灵活的低合规延伸管用于气球充气
公开(公告)号：US20130172923A1
公开(公告)日：2013-07-04
申请号：US13776568
申请日：2013-02-25
申请人： Abbott Cardiovascular Systems Inc.
发明人： William E. Webler , August R. Yambao
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/1204 , A61M25/0021 , A61M25/1002 , A61M25/10182 , A61M25/10188 , A61M25/1027 , A61M2025/1052
摘要： A controlled volume inflation-deflation device to inflate a balloon to occlude a blood vessel by dialing a knob that locks at rotational positions to locate a plunger at equally spaced locations within a syringe of the inflation-deflation device. The inflation-deflation device includes a releasable latch to lock the proximal and distal housings together to hold the plunger forward for occlusion, and to separate and hold the proximal and distal housings to retract the plunger for perfusion. When the inflation-deflation device is returned to the latched position, the balloon is re-inflated to its previous occlusive diameter. Also, an extension tube made of a lower modulus outer material co-extruded over and miscible with a higher modulus inner material may be used to produce a suitably low compliance extension tube for the inflation-deflation device. The balloon may have tapered ends and a cylindrical center portion so that it increases by more equal increments in outer diameter in response to incremental equal increases in inflation volume.
摘要翻译：一种受控体积的充气 - 放气装置，用于通过拨打锁定在旋转位置处的手柄来使气囊膨胀以封闭血管，以将柱塞定位在充气 - 放气装置的注射器内的等间隔位置。充气 - 放气装置包括可释放的闩锁，以将近端和远端壳体锁定在一起以将柱塞保持在前方用于闭塞，并且分离并保持近端和远端壳体以缩回柱塞用于灌注。当充气 - 放气装置返回到锁定位置时，将气囊重新膨胀至其先前的闭塞直径。此外，可以使用由较高模量的内部材料共挤出并可与较高模量的内部材料混合的由较低模量的外部材料制成的延伸管，以产生用于充气 - 收缩装置的合适的柔顺性延伸管。球囊可以具有锥形端部和圆柱形中心部分，使得响应于增加的充气体积的相等增加，其在外径上增加更多相等的增量。

88. 发明申请

US20130165963A1 Devices and Methods for Occluding or Promoting Fluid Flow 审中-公开
标题翻译：阻塞或促进流体流动的装置和方法
公开(公告)号：US20130165963A1
公开(公告)日：2013-06-27
申请号：US13333242
申请日：2011-12-21
申请人： James E. Coleman , Christy Cummins
发明人： James E. Coleman , Christy Cummins
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0487 , A61B17/11 , A61B17/12022 , A61B17/1204 , A61B17/12145 , A61B17/24 , A61B18/1492 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/00654 , A61B2017/00986 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/042 , A61B2017/0422 , A61B2017/0424 , A61B2017/0464 , A61B2017/0496 , A61B2017/1107 , A61B2017/1135 , A61B2017/12004 , A61B2017/22044 , A61B2017/22047 , A61B2017/4233 , A61B2018/00279 , A61B2018/00351 , A61B2018/00357 , A61F6/22 , F04C2270/041
摘要： Devices and methods for occluding or promoting fluid flow through openings are disclosed. In one exemplary embodiment an occlusion device is provided having an expandable outer elongate tubular body, a guide member extending from a distal end of the outer body, and a slide tube disposed within the outer body, the proximal portions of the outer body and the slide tube being fixedly mated. The slide tube is configured to slide distally within the outer tubular body when the tubular body is expanded to form wings. A tether can be included as part of the device and it can be used to assist in positioning and locking a location of the device in an opening. Exemplary methods for delivering devices disclosed herein are also provided.
摘要翻译：公开了用于封闭或促进流过开口的流体的装置和方法。在一个示例性实施例中，提供了闭塞装置，其具有可扩张的外部细长管状体，从外部主体的远端延伸的引导构件和设置在外部本体内的滑动管，外部本体的近端部分和滑块管固定配合。滑管构造成当管状体膨胀以形成翼片时在外管状体内向远侧滑动。可以将系绳作为装置的一部分包括在内，并可用于帮助将装置的位置定位和锁定在开口中。还提供了用于递送装置的示例性方法。

89. 发明申请

US20130165903A1 METHOD AND APPARATUS FOR CONTROLLED OCCLUSION 有权
标题翻译：控制灌注的方法和装置
公开(公告)号：US20130165903A1
公开(公告)日：2013-06-27
申请号：US13776579
申请日：2013-02-25
申请人： Abbott Cardiovascular Systems Inc.
发明人： William E. Webler , August R. Yambao
IPC分类号： A61B17/12 , A61M25/10
CPC分类号： A61B17/12022 , A61B17/1204 , A61M25/0021 , A61M25/1002 , A61M25/10182 , A61M25/10188 , A61M25/1027 , A61M2025/1052
摘要： A controlled volume inflation-deflation device to inflate a balloon to occlude a blood vessel by dialing a knob that locks at rotational positions to locate a plunger at equally spaced locations within a syringe of the inflation-deflation device. The inflation-deflation device includes a releasable latch to lock the proximal and distal housings together to hold the plunger forward for occlusion, and to separate and hold the proximal and distal housings to retract the plunger for perfusion. When the inflation-deflation device is returned to the latched position, the balloon is re-inflated to its previous occlusive diameter. Also, an extension tube made of a lower modulus outer material co-extruded over and miscible with a higher modulus inner material may be used to produce a suitably low compliance extension tube for the inflation-deflation device. The balloon may have tapered ends and a cylindrical center portion so that it increases by more equal increments in outer diameter in response to incremental equal increases in inflation volume.
摘要翻译：一种受控体积的充气 - 放气装置，用于通过拨打锁定在旋转位置处的手柄来使气囊膨胀以封闭血管，以将柱塞定位在充气 - 放气装置的注射器内的等间隔位置处。充气 - 放气装置包括可释放的闩锁，以将近端和远端壳体锁定在一起以将柱塞保持在前方用于闭塞，并且分离并保持近端和远端壳体以缩回柱塞用于灌注。当充气 - 放气装置返回到锁定位置时，将气囊重新膨胀至其先前的闭塞直径。此外，可以使用由较高模量的内部材料共挤出并可与较高模量的内部材料混合的由较低模量的外部材料制成的延伸管，以产生用于充气 - 收缩装置的合适的柔顺性延伸管。气球可以具有锥形端部和圆柱形中心部分，使得响应于增加的充气体积的相等增加，其在外径中增加更多相等的增量。

90. 发明申请

US20130165736A1 System And Method For Treating Heart Tissue 有权
标题翻译：治疗心脏组织的系统和方法
公开(公告)号：US20130165736A1
公开(公告)日：2013-06-27
申请号：US13336769
申请日：2011-12-23
申请人： Werner Mohl , Gregor Neumayr , Alem Jusic
发明人： Werner Mohl , Gregor Neumayr , Alem Jusic
IPC分类号： A61M1/12
CPC分类号： A61B17/12122 , A61B5/02028 , A61B5/0402 , A61B5/6859 , A61B5/6869 , A61B5/7239 , A61B5/742 , A61B17/1204 , A61B17/12136 , A61M25/1018 , A61M25/10184
摘要： Some embodiments of a system or method for treating heart tissue can include a control system and catheter device operated in a manner to intermittently occlude a heart vessel for controlled periods of time that provide redistribution of blood flow. In particular embodiments, the system and methods may be configured to monitor at least one input signal detected at a coronary sinus and thereby execute a process for determining a satisfactory time period for the occlusion of the coronary sinus. In further embodiments, after the occlusion of the coronary sinus is released, the control system can be configured to select the duration of the release phase before the starting the next occlusion cycle.
摘要翻译：用于治疗心脏组织的系统或方法的一些实施例可以包括控制系统和导管装置，其操作方式是间歇地闭塞心脏血管以控制血液流量再分配的时间段。在具体实施例中，系统和方法可以被配置为监视在冠状窦处检测到的至少一个输入信号，从而执行用于确定冠状静脉窦阻塞的令人满意的时间段的过程。在另外的实施例中，在冠状静脉窦闭塞之后，控制系统可被配置为在开始下一个闭塞循环之前选择释放阶段的持续时间。

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