专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明申请

US20050059844A1 Ethynylation process 失效
标题翻译：乙炔化过程
公开(公告)号：US20050059844A1
公开(公告)日：2005-03-17
申请号：US10489523
申请日：2002-09-19
申请人： Werner Bonrath , Bernd Englert , Reinhard Karge , Michael Schneider
发明人： Werner Bonrath , Bernd Englert , Reinhard Karge , Michael Schneider
IPC分类号： C07B61/00 , C07C29/42 , C07C33/042 , C07C33/048 , C07C27/18
CPC分类号： C07C29/42 , C07C33/02
摘要： A process for the manufacture of an acetylenically unsaturated alcohol comprising reacting formaldehyde, an aldehyde or a ketone (a carbonyl compound) with acetylene in the presence of ammonia and a strongly basic macroporous anion exchange resin, the latter preferably featuring a polystyrene matrix and quaternary ammonium groups, preferably of type I or Type II. The reaction products, which depending on the starting carbonyl compound are propargyl alcohol or 1-monosubstituted or 1,1-disubstituted derivatives thereof, are of use as intermediates in the synthesis of many useful end products, inter alia in the field of vitamins and carotenoids.
摘要翻译：一种制备炔属不饱和醇的方法，包括在氨和强碱性大孔阴离子交换树脂的存在下使甲醛，醛或酮（羰基化合物）与乙炔反应，后者优选具有聚苯乙烯基质和季铵组，优选I型或II型。取决于起始羰基化合物的反应产物是炔丙醇或其1-取代或1,1-二取代的衍生物，可用作合成许多有用的终产物的中间体，特别是在维生素和类胡萝卜素领域。

82. 发明授权

US06743615B2 Process for the manufacture of a vitamin E intermediate 有权
标题翻译：制备维生素E中间体的方法
公开(公告)号：US06743615B2
公开(公告)日：2004-06-01
申请号：US10078789
申请日：2002-02-19
申请人： Werner Bonrath , Detlef Eisenkraetzer , Valerie Enjolras , Reinhard Karge , Thomas Netscher , Michael Schneider
发明人： Werner Bonrath , Detlef Eisenkraetzer , Valerie Enjolras , Reinhard Karge , Thomas Netscher , Michael Schneider
IPC分类号： C12N914
CPC分类号： C12P7/62 , C12P17/06
摘要： The present invention is a process for converting trimethylhydroquinone diacetate (TMHQ-DA) into trimethylhydroquinone-1-monoacetate (TMHQ-1-MA) by contacting TMHQ-DA with a lipase to effect an enzymatic monosaponification of the TMHQ-DA. Also provided are methods of making (all-rac)-&agr;-tocopherol and (all-rac)-&agr;-tocopherol acetate.
摘要翻译：本发明是通过使TMHQ-DA与脂肪酶接触来实现TMHQ-DA的酶促单糖化来将三乙基氢醌二乙酸酯（TMHQ-DA）转化成三甲基氢醌-1-单乙酸酯（TMHQ-1-MA）的方法。还提供了制备（全消旋）-α-生育酚和（全消旋）-α-生育酚乙酸酯的方法。

83. 发明授权

US06482961B2 Method of making (all-rac)-&agr;-tocopherol 有权
标题翻译：制造（全脱色）-α-生育酚的方法
公开(公告)号：US06482961B2
公开(公告)日：2002-11-19
申请号：US09931663
申请日：2001-08-16
申请人： Werner Bonrath , Alois Haas , Eike Hoppmann , Horst Pauling
发明人： Werner Bonrath , Alois Haas , Eike Hoppmann , Horst Pauling
IPC分类号： C07D31104
CPC分类号： C07D311/72
摘要： The present invention is a method of making (all-rac)-&agr;-tocopherol in a reaction having the following steps: a) reacting trimethylhydroquinone and a phytol selected from the group consisting of isophytol and phytol in the presence of a bis(perfluorinated hydrocarbyl sulphonyl)imide catalyst or a metal salt thereof of formula I: [(R1SO2)2N]xR2 (I) wherein each R1, independently, signifies a perfluoroalkyl group CnF2n+1 or a pentafluorophenyl, or both symbols R1 together signify a poly-difluoromethylene group—(CF2)m—, with the proviso that both symbols R1 cannot simultaneously signify trifluoromethyl, R2 signifies a proton or a cationic form of a metal selected from the group consisting of boron, magnesium, aluminum, silicon, scandium, titanium, vanadium, manganese, iron, cobalt, nickel, copper, zinc, yttrium, zirconium, rhodium, palladium, silver, tin, lanthanum, cerium, praseodymium, neodymium, europium, dysprosium, thulium, ytterbium, hafnium, platinum, and gold, m is an integer from 2 to 4, n is an integer from 1 to 10, and x is the corresponding valency of the proton (1) or the metal cation (1, 2, 3, or 4), in organic solvent; and b) recovering (all-rac)-&agr;-tocopherol from the reaction mixture.
摘要翻译：本发明是在具有以下步骤的反应中制备（全脱氧）-α-生育酚的方法：a）在双（全氟化烃基）的存在下，使三甲基对苯二酚和选自异麦芽糖醇和植醇的植醇磺酰基）酰亚胺催化剂或其金属盐：其中R1独立地表示全氟烷基CnF2n + 1或五氟苯基，或两个符号R1一起表示聚二氟亚甲基 - （CF 2）m - ，条件是两个符号R1不能同时表示三氟甲基，R2表示选自硼，镁，铝，硅，钪，钛，钒，锰，铁，钴，镍，铜等的金属的质子或阳离子形式。锌，钇，锆，铑，钯，银，锡，镧，铈，镨，钕，铕，镝，ium，镱，铪，铂和金，m为2〜4的整数，n为 ger为1至10，andx为有机溶剂中质子（1）或金属阳离子（1,2,3或4）的相应化合价; 和b）从反应混合物中回收（全 - 外）-α-生育酚。

84. 发明授权

US06369242B2 Tocopherol manufacture by tris(perfluorohydrocarbylsulphonyl) methane or metal methides thereof 有权
标题翻译：由三（全氟代烃基磺酰基）甲烷或其金属甲基化物制造的生育酚
公开(公告)号：US06369242B2
公开(公告)日：2002-04-09
申请号：US09802272
申请日：2001-03-08
申请人： Werner Bonrath , Alois Haas , Eike Hoppmann , Thomas Netscher , Horst Pauling
发明人： Werner Bonrath , Alois Haas , Eike Hoppmann , Thomas Netscher , Horst Pauling
IPC分类号： C07D31104
CPC分类号： C07D311/72
摘要： A method of making (all-rac.)-&agr;-tocopherol by the acid-catalyzed condensation of trimethylhydroquinone with isophytol or phytol wherein the condensation is carried out in the presence of a tris(perfluoroalkanesulphonyl or pentafluorobenzenesulphonyl)methane or a metal salt thereof as the catalyst in an organic solvent. In addition to the metal salt, a Bronsted acid, e.g. sulfuric acid, phosphoric acid or p-toluenesulphonic acid, may be used as a co-catalyst. The product of the method of making is the most active member of the vitamin E group.
摘要翻译：通过三甲基氢醌与异植醇或植醇的酸催化缩合制备（全外消旋）-α-生育酚的方法，其中缩合在三（全氟烷基磺酰基或五氟苯磺酰基）甲烷或其金属盐存在下进行，为该催化剂在有机溶剂中。除了金属盐，布朗斯台德酸，例如，硫酸，磷酸或对甲苯磺酸可用作助催化剂。制作方法的产物是维生素E组中最活跃的成员。

85. 发明授权

US08916715B2 Process for 4-methyloxazole-5-carboxamide 有权
标题翻译： 4-甲基恶唑-5-甲酰胺的方法
公开(公告)号：US08916715B2
公开(公告)日：2014-12-23
申请号：US14127610
申请日：2012-05-31
申请人： Werner Bonrath , Jocelyn Fischesser , Hongyan Shen
发明人： Werner Bonrath , Jocelyn Fischesser , Hongyan Shen
IPC分类号： C07D263/34 , C07D213/69
CPC分类号： C07D263/34 , C07D213/69
摘要： A process for the preparation of 4-methyl-oxazole-5-carboxamide, an intermediate in the synthesis of pyridoxine, by reacting lower alkyl 4-methyl-oxazole-5-carboxy-late with a molar excess of anhydrous, liquid ammonia.
摘要翻译：通过将4-甲基 - 恶唑-5-羧基 - 低级烷基与摩尔过量的无水液氨反应，制备4-甲基 - 恶唑-5-甲酰胺（合成吡哆醇的中间体）的方法。

86. 发明授权

US08829231B2 Preparation of 4-acetoxy-2-methylbutanal by catalytic carbon carbon double bond hydrogenation 有权
标题翻译：通过催化碳碳双键氢化制备4-乙酰氧基-2-甲基丁醛
公开(公告)号：US08829231B2
公开(公告)日：2014-09-09
申请号：US13980118
申请日：2012-01-16
申请人： Werner Bonrath , Jan Schütz
发明人： Werner Bonrath , Jan Schütz
IPC分类号： C07C67/02
CPC分类号： C07C67/283 , C07C69/14
摘要： The present invention relates to a new way for the production of 4-acetoxy-2-methyl-butanal, wherein a non-acidic catalytic system is used.
摘要翻译：本发明涉及生产4-乙酰氧基-2-甲基 - 丁醛的新方法，其中使用非酸性催化体系。

87. 发明授权

US08802898B2 Isomerization of β-keto-allenes 有权
标题翻译：异构化和共聚物
公开(公告)号：US08802898B2
公开(公告)日：2014-08-12
申请号：US13642047
申请日：2011-04-18
申请人： Werner Bonrath , Reinhard Karge , Thomas Netscher , Yann Pressel
发明人： Werner Bonrath , Reinhard Karge , Thomas Netscher , Yann Pressel
IPC分类号： C07C45/67
CPC分类号： C07C45/67 , B01J31/08 , B01J2231/52 , C07C49/203
摘要： Isomerization of β-keto-allenes of the general formula I wherein R1 is hydrogen, methyl or ethyl, in particular hydrogen or methyl; R2 is hydrogen or methyl; R3 is hydrogen or methyl, in particular methyl and R4 is an aliphatic hydrocarbon residue containing 1-37 carbon atoms, into corresponding α,γ-dienones of formula II by treatment with a basic ion exchange resin.
摘要翻译：其中R 1是氢，甲基或乙基，特别是氢或甲基的通式I的双 - 二烯的异构化; R2是氢或甲基; R3是氢或甲基，特别是甲基，R4是含有1-37个碳原子的脂族烃残基，通过碱性离子交换树脂的处理转化为相应的式II的α，γ-二烯酮。

88. 发明申请

US20140206880A1 PROCESS FOR 4-METHYLOXAZOLE-5-CARBOXAMIDE 有权
标题翻译： 4-甲氧基噻唑-5-羧酰胺的方法
公开(公告)号：US20140206880A1
公开(公告)日：2014-07-24
申请号：US14127610
申请日：2012-05-31
申请人： Werner Bonrath , Jocelyn Fischesser , Hongyan Shen
发明人： Werner Bonrath , Jocelyn Fischesser , Hongyan Shen
IPC分类号： C07D263/34 , C07D213/69
CPC分类号： C07D263/34 , C07D213/69
摘要： A process for the preparation of 4-methyl-oxazole-5-carboxamide, an intermediate in the synthesis of pyridoxine, by reacting lower alkyl 4-methyl-oxazole-5-carboxy-late with a molar excess of anhydrous, liquid ammonia.
摘要翻译：通过将4-甲基 - 恶唑-5-羧基 - 低级烷基与摩尔过量的无水液氨反应，制备4-甲基 - 恶唑-5-甲酰胺（一种合成吡哆醇的中间体）的方法。

89. 发明申请

US20140081042A1 PREPARATION OF 4-ACETOXY-2-METHYLBUTANAL BY CATALYTIC CARBON CARBON DOUBLE BOND HYDROGENATION 有权
标题翻译：通过催化碳碳双酚氢化制备4-乙酰氧基-2-甲基吡啶
公开(公告)号：US20140081042A1
公开(公告)日：2014-03-20
申请号：US13980118
申请日：2012-01-16
申请人： Werner Bonrath , Jan Schütz
发明人： Werner Bonrath , Jan Schütz
IPC分类号： C07C67/283
CPC分类号： C07C67/283 , C07C69/14
摘要： The present invention relates to a new way for the production of 4-acetoxy-2-methyl-butanal, wherein a non-acidic catalytic system is used.
摘要翻译：本发明涉及生产4-乙酰氧基-2-甲基 - 丁醛的新方法，其中使用非酸性催化体系。

90. 发明授权

US08592636B2 Hydrogenation process 有权
标题翻译：氢化过程
公开(公告)号：US08592636B2
公开(公告)日：2013-11-26
申请号：US13575096
申请日：2011-01-28
申请人： Werner Bonrath , Thomas Mueller , Lioubov Kiwi-Minsker , Albert Renken , Igor Iouranov
发明人： Werner Bonrath , Thomas Mueller , Lioubov Kiwi-Minsker , Albert Renken , Igor Iouranov
IPC分类号： C07C29/17
CPC分类号： B01J37/0242 , B01J23/60 , B01J35/06 , B01J37/0226 , B01J37/0244 , C07C29/17 , C07C33/03
摘要： The present invention relates to a process of reacting specific compounds, which are defined below with hydrogen in the presence of a structured catalyst based on sintered metal fibers (SMF) coated by a ZnO layer with Pd-nanoparticles, to reactions of these specific compounds with hydrogen in the presence of said catalyst and an organic base as well as to vitamins, carotinoids, perfume ingredients, and/or food or feed ingredients prepared by using this reaction.
摘要翻译：本发明涉及一种将基于烧结金属纤维（SMF）的ZnO层与Pd-纳米粒子涂覆的结构化催化剂存在下将下文定义的特定化合物反应的方法，涉及这些具体化合物与所述催化剂和有机碱存在下的氢，以及通过使用该反应制备的维生素，类胡萝卜素，香料成分和/或食品或饲料成分。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式