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81. 发明授权

US09352089B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09352089B2
公开(公告)日：2016-05-31
申请号：US13807140
申请日：2011-06-27
申请人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/315 , A61M5/32 , A61M5/46
CPC分类号： A61M5/2033 , A61M5/31511 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208
摘要： An auto-injector comprising a housing arranged to contain a syringe. The syringe is slidably arranged with respect to the housing, a spring capable of pushing a needle from a covered position into an advanced position, operating the syringe to supply a dose of medicament, and retracting the syringe into a covered position and an activator. The spring is arranged to be grounded in the housing for advancing the needle and for injecting the dose of medicament. The drive spring grounded in the housing switched to its proximal end for retracting the syringe. An interlock sleeve telescoped within the housing. The activator comprises a trigger, wherein the trigger button is locked, thereby preventing actuation when the interlock sleeve is in its proximal position in an as delivered state and wherein translation of the interlock sleeve unlocks the trigger button so as to allow actuation.
摘要翻译：一种自动注射器，包括布置成容纳注射器的壳体。注射器相对于壳体可滑动地布置，弹簧能够将针从覆盖位置推入前进位置，操作注射器以供应一定剂量的药物，并将注射器缩回到覆盖位置和活化剂。弹簧布置成在壳体中接地以推进针头并注射剂量的药物。接地在壳体中的驱动弹簧切换到其近端以缩回注射器。在壳体内伸缩的互锁套筒。激活器包括触发器，其中触发器按钮被锁定，从而当互锁套筒处于处于其传送状态的近端位置时防止致动，并且其中互锁套筒的平移解除触发按钮以允许致动。

82. 发明授权

US09295787B2 Adapter means for use in combination with a pre-filled syringe and a safety device, safety device and injection device 有权
标题翻译：适配器装置可与预装注射器和安全装置，安全装置和注射装置结合使用
公开(公告)号：US09295787B2
公开(公告)日：2016-03-29
申请号：US13976417
申请日：2011-12-30
申请人： Gareth Roberts , Sioned Owen , Matthew Ekman
发明人： Gareth Roberts , Sioned Owen , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/28
CPC分类号： A61M5/3243 , A61M5/28 , A61M5/326 , A61M5/3271 , A61M2005/3247
摘要： According to the invention, an adaptor means for use in combination with a pre-filled syringe and a safety device for the pre-filled syringe is adapted to affix the pre-filled syringe thereto, whereby the adaptor means engages a barrel of the pre-filled syringe. The adaptor means comprises at least one locking projection that is adapted to lock the adaptor means to the safety device.
摘要翻译：根据本发明，用于与预填充的注射器组合的适配器装置和用于预填充的注射器的安全装置适于将预填充的注射器固定到其上，由此适配器装置接合预充填的注射器的筒，填充注射器。适配器装置包括适于将适配器装置锁定到安全装置的至少一个锁定突起。

83. 发明授权

US09242047B2 Detent mechanism 有权
标题翻译：拘留机制
公开(公告)号：US09242047B2
公开(公告)日：2016-01-26
申请号：US13985253
申请日：2012-02-16
申请人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/315 , A61M5/20
CPC分类号： A61M5/3158 , A61M5/2033 , A61M5/31501 , A61M5/31511 , A61M5/3157 , A61M5/3202 , A61M5/3204 , A61M5/3257 , A61M5/326 , A61M5/46 , A61M5/5086 , A61M2005/2013 , A61M2005/206 , A61M2005/208 , A61M2005/3247 , A61M2205/581 , A61M2205/582 , F04C2270/0421 , Y10T403/32501
摘要： The invention relates to a detent mechanism for controlling translation between two components in a longitudinal direction, the detent mechanism comprising a resilient beam on one of the components and a rhomboid ramp member on the other component, the resilient beam being essentially straight when relaxed and having a first beam head and arranged to interact in a ramped engagement with respectively one of two ramps, each ramp on one longitudinal side of the rhomboid ramp member in such a manner that application of a translative force between the components in one longitudinal direction with the first beam head engaged to one of the ramps in a first state deflects the resilient beam in one transversal direction when a predetermined value of the translative force, at least depending on the resilience of the resilient beam, is overcome so as to allow the first beam head to travel along one transversal side of the rhomboid ramp member on continued relative translation of the components, wherein the resilient beam is allowed to relax when the first beam head has reached the other one of the ramps in a second state, wherein application of a translative force between the components in the other longitudinal direction with the first beam head engaged to the other one of the ramps deflects the resilient beam in the other transversal direction when a predetermined value of the translative force, at least depending on the resilience of the resilient beam, is overcome so as to allow the first beam head to travel along the other transversal side of the rhomboid ramp member on continued relative translation of the components.
摘要翻译：本发明涉及一种用于在纵向方向上控制两个部件之间的平移的止动机构，所述制动机构包括在其中一个部件上的弹性梁和另一部件上的菱形斜坡部件，弹性梁在松弛时基本上是直的，第一光束头并且布置成与两个斜面中的一个坡道接合地相互作用，每个斜坡在所述菱形斜坡构件的一个纵向侧上以这样的方式相互作用，使得在一个纵向方向上的部件之间的平移力与第一当第一状态中的一个斜面接合到一个斜面时，当至少取决于弹性梁的弹性的平移力的预定值被克服以允许第一梁头沿着菱形斜坡构件的一个横向方向沿组件的连续相对平移行进，w 这里，当第一光束头在第二状态下已经到达另一个斜面时，使弹性光束松弛，其中在另一个纵向方向上的部件之间施加平移力，第一光束头与另一个接合当至少取决于弹性梁的弹性的平移力的预定值被克服以允许第一梁头沿另一横向方向的另一横向侧行进时，斜面在另一个横向方向上使弹性梁偏转菱形斜坡构件继续相对翻译组件。

84. 发明授权

US09242045B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09242045B2
公开(公告)日：2016-01-26
申请号：US13876168
申请日：2011-10-06
申请人： Rosie Burnell , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Rosie Burnell , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/2033 , A61M5/3202 , A61M2005/206 , A61M2005/2073
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising a housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing, drive means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, and operating the syringe to supply the dose of medicament, and activating means arranged to lock the drive means in a loaded state prior to manual operation and capable of, upon manual operation, releasing the drive means for injection, characterized in that the drive means is at least one spring essentially transversally arranged with respect to a longitudinal axis of the syringe at least when in the loaded state.
摘要翻译：本发明涉及一种用于施用一剂液体药物的自动注射器，其包括被布置成容纳具有中空针的注射器的壳体和用于密封注射器并使药剂移位的塞子，该壳体具有远端和近端末端具有旨在施加到注射部位的孔口，其中所述注射器相对于所述壳体可滑动地布置，所述驱动装置能够在启动时将所述针头从所述壳体内的覆盖位置推入通过所述孔口的前进位置并且通过近端操作，并且操作注射器以供应剂量的药剂;以及激活装置，其布置成在手动操作之前将驱动装置锁定在加载状态，并且能够在手动操作时释放用于注射的驱动装置，其特征在于因为驱动装置至少是至少一个弹簧，至少基本上横向地相对于注射器的纵向轴线布置加载状态。

85. 发明授权

US09067024B2 Safety device for a pre-filled syringe and injection device 有权
标题翻译：预充注射器和注射装置的安全装置
公开(公告)号：US09067024B2
公开(公告)日：2015-06-30
申请号：US13807045
申请日：2011-06-21
申请人： Gareth Roberts , Sioned Owen , Matthew Ekman
发明人： Gareth Roberts , Sioned Owen , Matthew Ekman
IPC分类号： A61M5/00 , A61M5/32 , A61M5/315 , A61M5/50
CPC分类号： A61M5/3245 , A61M5/31568 , A61M5/3157 , A61M5/3202 , A61M5/326 , A61M5/3287 , A61M5/502 , A61M2005/3247 , A61M2005/3267 , A61M2205/581 , A61M2205/583
摘要： A safety device for a pre-filled syringe comprises a hollow support body to retain the pre-filled syringe, a retaining collar and a rotating collar arranged within the support body. The retaining collar is releasably mounted to the support body. The rotating collar is slidable along an axial length of the support body and rotatable around a central axis of the safety device. The retaining collar is movable with respect to the support body in a proximal direction when the retaining collar is released from being mounted to the support body by the rotating collar.
摘要翻译：用于预填充注射器的安全装置包括中空支撑体，以保持预填充的注射器，保持套环和布置在支撑体内的旋转套环。保持环可释放地安装到支撑体上。旋转轴环可以沿着支撑体的轴向长度滑动并可围绕安全装置的中心轴线旋转。当保持套环通过旋转套环被释放而不能安装到支撑体时，保持套环能够在近端方向上相对于支撑体移动。

86. 发明授权

US08911401B2 Safety device for a pre-filled syringe and injection device 有权
标题翻译：预充注射器和注射装置的安全装置
公开(公告)号：US08911401B2
公开(公告)日：2014-12-16
申请号：US13807044
申请日：2011-06-21
申请人： Gareth Roberts , Chris Ward , Matthew Ekman
发明人： Gareth Roberts , Chris Ward , Matthew Ekman
IPC分类号： A61M5/00 , A61M5/32 , A61M5/28
CPC分类号： A61M5/3272 , A61M5/28 , A61M5/3202 , A61M5/3204 , A61M5/326 , A61M5/3287 , A61M2005/3267
摘要： According to the invention, an injection device (D) comprises a pre-filled syringe and a safety device. The pre-filled syringe comprises a barrel with an inner cavity in fluid communication with a hypodermic needle attached to a distal end of the pre-filled syringe and a piston fluid-tightly sealing a proximal end of the inner cavity. The safety device comprises a support body for retaining the pre-filled syringe therein, an outer body operably connected to the piston, a needle shield and a releasable retaining means (R). The retaining means comprises a radial projection and a longitudinal recess adapted to receive the radial projection. The radial projection is connected to or integral part of one of the support body or the outer body and a longitudinal recess formed into the other of the support body or the outer body. The needle shield, the support body and the outer body are telescopable relative to each other. The piston is movable in a distal direction to expel a medicament contained in the inner cavity through the hypodermic needle by a manual actuation of the outer body. A telescoping movement of the outer body with respect to the support body is restricted by the retaining means (R) when the needle shield is moved with respect to the support body in a proximal direction from an initial position (I) towards a retracted position (II). The retaining means (R) is released when the needle shield reaches the retracted position (II) allowing for a telescoping movement of the outer body with respect to the support body to expel the medicament contained in the pre-filled syringe through the hypodermic needle.
摘要翻译：根据本发明，注射装置（D）包括预填充注射器和安全装置。预填充注射器包括具有与附接到预填充注射器的远端的皮下注射针流体连通的内腔的筒体和活塞，其密封地密封内腔的近端。安全装置包括用于将预填充的注射器保持在其中的支撑体，可操作地连接到活塞的外部主体，针护罩和可释放的保持装置（R）。保持装置包括径向突起和适于接收径向突起的纵向凹部。径向突起连接到支撑体或外体中的一个或整体的一部分，以及形成在支撑体或外体中的另一个中的纵向凹部。针护罩，支撑体和外体可相对于彼此可伸缩。活塞可以在远端方向上移动，以通过外部身体的手动致动来通过皮下注射针排出包含在内腔中的药物。当针护罩相对于支撑体从初始位置（I）朝向缩回位置的近端方向移动时，外主体相对于支撑体的伸缩运动被保持装置（R）限制（ II）。当针护罩到达缩回位置（II）时，保持装置（R）被释放，允许外主体相对于支撑体的伸缩运动，以通过皮下注射针排出包含在预先填充的注射器中的药物。

87. 发明申请

US20140303564A1 SAFETY DEVICE FOR A PRE-FILLED SYRINGE AND INJECTION DEVICE 有权
标题翻译：一种预充式注射器和注射装置的安全装置
公开(公告)号：US20140303564A1
公开(公告)日：2014-10-09
申请号：US13808070
申请日：2011-06-21
申请人： Gareth Roberts , Sioned Owen , Matthew Ekman
发明人： Gareth Roberts , Sioned Owen , Matthew Ekman
IPC分类号： A61M5/32
CPC分类号： A61M5/3271 , A61M5/28 , A61M5/3213 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M2005/3267
摘要： A safety device for a pre-filled syringe comprises a hollow support body to retain the pre-filled syringe therein, a hollow needle shield that is slidable relative to the support body and guiding means for guiding the movement of the needle shield relative to the support body. The guiding means comprise a deflectable flexible arm, a guide pin and a guide track. The deflectable flexible arm extends essentially parallel to a central axis of the safety device. The guide pin extends radial from the flexible arm. The guide track guides the guide pin within and along the guide track when the needle shield is slid relative to the support body.
摘要翻译：用于预填充注射器的安全装置包括中空支撑体，用于将预填充的注射器保持在其中，中空的针护罩，其可相对于支撑体滑动;以及引导装置，用于引导针护罩相对于支撑件的运动身体。引导装置包括可偏转的柔性臂，引导销和引导轨道。可偏转的柔性臂基本上平行于安全装置的中心轴线延伸。导向销从柔性臂径向延伸。当针护罩相对于支撑体滑动时，导轨将引导件引导到引导轨道内和沿导轨。

88. 发明申请

US20130331794A1 Safety Device for a Pre-Filled Syringe, Injection Device and Injection Kit 有权
标题翻译：预灌注注射器，注射装置和注射套件的安全装置
公开(公告)号：US20130331794A1
公开(公告)日：2013-12-12
申请号：US13808023
申请日：2011-06-21
申请人： Matthew Ekman , Christopher James Smith , Troy Baker , Graham Wilson , Gareth Roberts , John Slemmen
发明人： Matthew Ekman , Christopher James Smith , Troy Baker , Graham Wilson , Gareth Roberts , John Slemmen
IPC分类号： A61M5/32
CPC分类号： A61M5/3204 , A61M5/28 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M2005/3267
摘要： According to the invention, a safety device for a pre-filled syringe comprises a hollow support body to retain the pre-filled syringe therein, a hollow needle shield that is slidable relative to the support body and guiding means for guiding the movement of the needle shield relative to the support body. The guiding means comprise a guide pin, a guide track and a cut-out adjacent to the guide track. The guide pin protrudes into the guide track and moves within and along the guide track when the needle shield is slid relative to the support body. The cut-out allows a side wall of the guide track to be deflected in a lateral direction perpendicular to a central axis of the safety device.
摘要翻译：根据本发明，用于预填充注射器的安全装置包括中空支撑体，用于将预填充的注射器保持在其中，相对于支撑体可滑动的中空针护罩和用于引导针的运动的引导装置屏蔽相对于支撑体。引导装置包括导向销，导轨和与导轨相邻的切口。当针护罩相对于支撑体滑动时，引导销突出到导轨中并沿导轨移动。切口允许导轨的侧壁在垂直于安全装置的中心轴线的横向方向上偏转。

89. 发明申请

US20130324924A1 Auto-Injector 有权
标题翻译：自动进样器
公开(公告)号：US20130324924A1
公开(公告)日：2013-12-05
申请号：US13984849
申请日：2012-02-16
申请人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/3129 , A61M2005/2026 , A61M2005/2073
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate case arranged to be held by a user, a tubular chassis telescopable in the case and biased against the case so as to protrude from the case, a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, a trigger button which is initially abutted against the case thus preventing actuation, wherein the chassis is arranged to translate into the case against the bias when pressed against an injection site, wherein the trigger button is at least initially coupled to the chassis in such a manner that the trigger button emerges from the case when the chassis is being pressed against the injection site so as to allow actuation by being translated towards the case for starting an injection cycle.
摘要翻译：本发明涉及一种用于施用一剂液体药物的自动注射器，其包括：布置成由使用者握持的细长壳体，可伸缩的壳体中的管状底座，并且抵靠壳体从外壳突出，具有中空注射针的注射器，驱动弹簧和用于将驱动弹簧的负载传递到注射器的止动件的柱塞;触发器按钮，其最初抵靠壳体抵靠，从而防止致动，其中底盘被布置成平移到当按压在注射部位时抵抗偏压的情况，其中触发按钮至少首先以这样的方式联接到底盘，即当底架被压靠在注射部位上时触发按钮从壳体出来以允许通过向开始注射循环的情况转移而致动。

90. 发明申请

US20130324923A1 Safety Device for a Pre-Filled Syringe and Injection Device 有权
标题翻译：预充注射器和注射装置的安全装置
公开(公告)号：US20130324923A1
公开(公告)日：2013-12-05
申请号：US13808084
申请日：2011-06-21
申请人： Gareth Roberts , Chris Ward , Matthew Ekman
发明人： Gareth Roberts , Chris Ward , Matthew Ekman
IPC分类号： A61M5/32
CPC分类号： A61M5/3204 , A61M5/28 , A61M5/326 , A61M5/3272 , A61M2005/3267
摘要： According to the invention, a safety device for a pre-filled syringe comprises a hollow support body for mounting the pre-filled syringe therein, a hollow needle shield that is slidable relative to the support body and guiding means for guiding the movement of the needle shield relative to the support body. The guiding means comprise a flexible arm with a guide pin, a guide track and a separating wall. The guide pin extends from the flexible arm in a radial direction, and protrudes into the guide track. The separating wall extends into the guide track in a direction parallel to a central axis of the safety device. When the needle shield is slid relative to the support body the guide pin moves along the guide track to deflect the flexible arm in a lateral direction perpendicular to the central axis and the movement of the guide pin along the guide track is guided by the interplay of the flexible arm and the separating wall.
摘要翻译：根据本发明，用于预填充注射器的安全装置包括用于将预填充的注射器安装在其中的中空支撑体，相对于支撑体可滑动的中空针护罩和用于引导针的运动的引导装置屏蔽相对于支撑体。引导装置包括具有引导销，导轨和分隔壁的柔性臂。引导销从柔性臂沿径向方向延伸并突出到导轨中。分隔壁沿平行于安全装置的中心轴线的方向延伸到导轨中。当针罩相对于支撑体滑动时，引导销沿导轨移动，以使柔性臂沿垂直于中心轴线的横向方向偏转，并且引导销沿着导轨的移动由相互作用引导柔性臂和分隔壁。

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