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    • 86. 发明授权
    • Target substance detection element, target substance detection method, and method for producing target substance detection element
    • 靶物质检测元件,目标物质检测方法以及靶物质检测元件的制造方法
    • US08183058B2
    • 2012-05-22
    • US12524348
    • 2008-03-17
    • Satoru HatakeyamaTakashi Ikeda
    • Satoru HatakeyamaTakashi Ikeda
    • G01N33/543
    • G01N33/54386G01N33/54393Y10S435/97Y10S436/807Y10T156/10
    • It is intended to provide a target substance detection element wherein a target substance capturing body for capturing target substances is immobilized with good orientation in a desired region on the surface of the target substance detection element, a method for producing the target substance detection element, and a detection method using the target substance detection element. The present invention provides a target substance detection element for detecting the presence or absence or concentration of a target substance in a sample, characterized in that: the target substance detection element includes at least a detection substrate including plural layers and a target substance capturing body immobilized on the surface of the detection substrate; the target substance capturing body has at least a first peptide region specifically recognizing a first layer of the plural layers constituting the detection substrate and binding to the first layer and a second peptide region specifically recognizing a second layer different from the first layer of the plural layers and binding to the second layer; and the first layer and the second layer are adjacent to each other.
    • 旨在提供一种目标物质检测元件,其中用于捕获目标物质的目标物质捕获体被固定在目标物质检测元件的表面上的期望区域中具有良好取向,该目标物质检测元件的制造方法和 使用目标物质检测元件的检测方法。 本发明提供了一种用于检测样品中目标物质的存在或不存在或浓度的目标物质检测元件,其特征在于:所述目标物质检测元件至少包括包含多层的检测基板和固定的靶物质捕获体 在检测基板的表面上; 目标物质捕捉体具有至少第一肽区域,其具体地识别构成检测基板的多层的第一层并与第一层结合,以及特异性识别与多层的第一层不同的第二层的第二肽区域 并与第二层结合; 并且第一层和第二层彼此相邻。