专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明申请

US20100067001A1 OPTICAL MASK FOR DETECTOR OPTIMIZATION 有权
标题翻译：用于探测器优化的光学遮罩
公开(公告)号：US20100067001A1
公开(公告)日：2010-03-18
申请号：US12559294
申请日：2009-09-14
申请人： James L. Corbeil , Nan Zhang
发明人： James L. Corbeil , Nan Zhang
IPC分类号： G01J3/28 , B32B37/00 , B05D5/06
CPC分类号： G01T1/00 , Y10T156/10
摘要： An optical mask positioned on a scintillator array. The optical mask includes a reflective layer. One or more windows can be positioned on the surface of optical mask.
摘要翻译：位于闪烁体阵列上的光学掩模。光学掩模包括反射层。一个或多个窗口可以位于光学掩模的表面上。

82. 发明申请

US20100015141A1 4-PHENOXY-6-ARYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE AND N-ARYL-6-ARYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES 审中-公开
标题翻译： 4-苯基-6-芳基-1H-吡唑并[3,4-D]吡嗪和N-芳基-6-芳基-1H-吡唑并[3,4-D]嘧啶-4-胺化合物，它们作为MTOR KINASE 和PI3激酶抑制剂及其合成
公开(公告)号：US20100015141A1
公开(公告)日：2010-01-21
申请号：US12506291
申请日：2009-07-21
申请人： Matthew Gregory Bursavich , Pawel Wojciech Nowak , David Malwitz , Sabrina Lombardi , Adam Matthew Gilbert , Nan Zhang , Semiramis Ayral-Kaloustian , James Thomas Anderson , Natasja Brooijmans
发明人： Matthew Gregory Bursavich , Pawel Wojciech Nowak , David Malwitz , Sabrina Lombardi , Adam Matthew Gilbert , Nan Zhang , Semiramis Ayral-Kaloustian , James Thomas Anderson , Natasja Brooijmans
IPC分类号： A61K31/519 , C07D487/04 , A61K39/395 , A61P35/00
CPC分类号： C07D487/04
摘要： The invention relates to 4,6-disubstituted-1H-pyrazolo[3,4-d]pyrimidin-4-amine compounds, including 4-phenoxy-6-aryl-1H-pyrazolo[3,4-d]pyrimidine and N-aryl-6-aryl-1H-pyrazolo[3,4-d]pyrimidin-4-amine compounds of the Formula I: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
摘要翻译：本发明涉及4,6-二取代-1H-吡唑并[3,4-d]嘧啶-4-胺化合物，包括4-苯氧基-6-芳基-1H-吡唑并[3,4-d]嘧啶和N- 芳基-6-芳基-1H-吡唑并[3,4-d]嘧啶-4-胺化合物或其药学上可接受的盐，其中组成变量如本文所定义，包含该化合物的组合物和方法用于制造和使用这些化合物。

83. 发明授权

US07603203B2 Method for voltage instability load shedding using local measurements 有权
标题翻译：使用局部测量的电压不稳定性负载脱落方法
公开(公告)号：US07603203B2
公开(公告)日：2009-10-13
申请号：US11539758
申请日：2006-10-09
申请人： Pei Zhang , Liang Min , Nan Zhang
发明人： Pei Zhang , Liang Min , Nan Zhang
IPC分类号： G05D5/00
CPC分类号： H02J3/14 , H02J3/24 , Y02B70/3225 , Y04S20/222
摘要： A method of voltage instability load shedding, that includes the steps of measuring current and voltage waveforms of an electrical system at a local bus estimating the Thevenin equivalent admittance based on Kalman Filter techniques, then a voltage stability margin index is calculated using the voltage magnitude. The determined Thevenin admittance and the load at the local system bus and the calculated voltage stability margin index is compared with a predetermined threshold value to determine whether to initiate a load shedding action.
摘要翻译：一种电压不稳定性负载脱落的方法，其中包括测量基于卡尔曼滤波技术估算戴维南等效导纳的局部总线上电气系统的电流和电压波形的步骤，然后使用电压幅值计算电压稳定裕度指数。将确定的戴维宁导纳和本地系统总线的负载以及计算的电压稳定性裕度指数与预定阈值进行比较，以确定是否启动负载脱落动作。

84. 发明授权

US07524849B2 5-arylpyrimidines as anticancer agents 有权
标题翻译： 5-芳基嘧啶作为抗癌剂
公开(公告)号：US07524849B2
公开(公告)日：2009-04-28
申请号：US10950375
申请日：2004-09-24
申请人： Nan Zhang , Semiramis Ayral-Kaloustian , Thai Nguyen
发明人： Nan Zhang , Semiramis Ayral-Kaloustian , Thai Nguyen
IPC分类号： C07D239/42 , C07D239/48 , A61K31/505
CPC分类号： C07D239/42 , A61K31/505 , A61K31/506 , C07D239/48 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04
摘要： This invention relates to certain 5-arylpyrimidine compounds or a pharmaceutically acceptable salt thereof, and compositions containing said compounds or a pharmaceutically acceptable salt thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or a pharmaceutically acceptable salt thereof.More specifically, the present invention relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal in need thereof by promotion of microtubule polymerization which comprises administering to said mammal an effective amount of said compounds and pharmaceutically acceptable salts thereof.
摘要翻译：本发明涉及某些5-芳基嘧啶化合物或其药学上可接受的盐，以及含有所述化合物或其药学上可接受的盐的组合物，其中所述化合物是可用于治疗哺乳动物癌症的抗癌剂。本发明还涉及治疗或抑制哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，并进一步提供了治疗或预防表达多重耐药性（MDR）或耐多药耐药性的癌性肿瘤的方法在需要的哺乳动物中，所述方法包括向所述哺乳动物施用有效量的所述化合物或其药学上可接受的盐。更具体地，本发明涉及通过促进微管聚合来治疗或抑制有需要的哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，其包括向所述哺乳动物施用有效量的所述化合物和药学上可接受的盐其中。

85. 发明申请

US20090072151A1 Parameter Adjustment for Medical Device 有权
标题翻译：医疗器械参数调整
公开(公告)号：US20090072151A1
公开(公告)日：2009-03-19
申请号：US11941562
申请日：2007-11-16
申请人： Nan Zhang , Volker Matschl , Niraj K. Doshi , Matthias J. Schmand
发明人： Nan Zhang , Volker Matschl , Niraj K. Doshi , Matthias J. Schmand
IPC分类号： G01T1/164 , H04B3/54
CPC分类号： A61B6/037 , A61B6/56
摘要： A medical device with a high voltage connection line for carrying a high DC supply voltage has a control unit generating said high DC supply voltage which is fed through a first AC block unit to said high voltage connection line and generating a digital control signal fed through a first AC coupling unit to said high voltage connection line, and a remotely located unit a second AC block unit coupled to said high voltage connection line for receiving said high DC supply voltage and a second AC coupling unit coupled to said high voltage connection line for receiving said digital control signal.
摘要翻译：具有用于承载高直流电源电压的高压连接线的医疗装置具有产生所述高直流电源电压的控制单元，所述高直流电源电压通过第一AC块单元馈送到所述高压连接线，并产生通过第一AC耦合单元连接到所述高压连接线，以及远程定位单元，耦合到所述高压连接线的第二AC块单元，用于接收所述高DC电源电压;以及第二AC耦合单元，耦合到所述高压连接线，用于接收所述数字控制信号。

86. 发明申请

US20080201551A1 Virtual disk router system and virtual disk access system and method therefor 审中-公开
标题翻译：虚拟磁盘路由器系统和虚拟磁盘访问系统及其方法
公开(公告)号：US20080201551A1
公开(公告)日：2008-08-21
申请号：US11707875
申请日：2007-02-20
申请人： Nan Zhang , Rui Zhang , Tom Chen , Win-Harn Liu
发明人： Nan Zhang , Rui Zhang , Tom Chen , Win-Harn Liu
IPC分类号： G06F12/10
CPC分类号： G06F3/0665 , G06F3/0607 , G06F3/0635 , G06F3/067
摘要： A virtual disk (VD) router system, a VD access system, and a method therefor, applied to a dual-controller system including a first controller and a second controller, are provided. First, a mapping virtual block device (VBD) corresponding to a VD of the second controller and/or the first controller is established in the first controller and/or the second controller, and a mapping relation list and a data transmission channel of the VD and the corresponding VBD thereof are established. When the first controller/the second controller issues an access request to the VD of the second controller/the first controller, the data transmission channel is used to transmit the access request to the VD and transmit the response data to the access request from the VD. Therefore, the overall access to all the VDs in the dual-controller system can be achieved.
摘要翻译：提供了应用于包括第一控制器和第二控制器的双控制器系统的虚拟磁盘（VD）路由器系统，VD访问系统及其方法。首先，在第一控制器和/或第二控制器中建立对应于第二控制器和/或第一控制器的VD的映射虚拟块设备（VBD），以及VD的映射关系列表和数据传输信道并建立相应的VBD。当第一控制器/第二控制器向第二控制器/第一控制器的VD发出访问请求时，使用数据传输信道将访问请求发送到VD，并将响应数据从VD发送到访问请求。因此，可以实现双控制器系统中所有VD的整体访问。

87. 发明授权

US07285555B2 6-aryl-7-halo-imidazo[1,2-a]pyrimidines as anticancer agents 失效
标题翻译： 6-芳基-7-卤代咪唑并[1,2-a]嘧啶作为抗癌剂
公开(公告)号：US07285555B2
公开(公告)日：2007-10-23
申请号：US10950542
申请日：2004-09-24
申请人： Nan Zhang , Semiramis Ayral-Kaloustian
发明人： Nan Zhang , Semiramis Ayral-Kaloustian
IPC分类号： A61K31/519 , C07D487/04 , A61P35/04
CPC分类号： C07D487/04
摘要： This invention relates to certain 6-aryl-7-halo-imidazo[1,2-a]pyrimidines or pharmaceutically acceptable salts thereof, and compositions containing said compounds or pharmaceutically acceptable salts thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals by promotion of microtubule polymerization. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or pharmaceutically acceptable salts thereof.
摘要翻译：本发明涉及某些6-芳基-7-卤代咪唑并[1,2-a]嘧啶或其药学上可接受的盐，以及含有所述化合物或其药学上可接受的盐的组合物，其中所述化合物是可用于通过促进微管聚合治疗哺乳动物的癌症。本发明还涉及治疗或抑制哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，并进一步提供了治疗或预防表达多重耐药性（MDR）或耐多药耐药性的癌性肿瘤的方法在有需要的哺乳动物中，所述方法包括向所述哺乳动物施用有效量的所述化合物或其药学上可接受的盐。

88. 发明申请

US20060247217A1 Tricyclic protein kinase inhibitors 审中-公开
公开(公告)号：US20060247217A1
公开(公告)日：2006-11-02
申请号：US11478121
申请日：2006-06-29
申请人： Dan Berger , Minu Dutia , Frenel DeMorin , Diane Boschelli , Dennis Powell , Hwei-Ru Tsou , Allan Wissner , Nan Zhang , Fei Ye , Biqi Wu
发明人： Dan Berger , Minu Dutia , Frenel DeMorin , Diane Boschelli , Dennis Powell , Hwei-Ru Tsou , Allan Wissner , Nan Zhang , Fei Ye , Biqi Wu
IPC分类号： A61K31/496 , A61K31/655 , A61K31/4745 , A61K31/473 , C07D498/02 , C07D491/02
CPC分类号： C07D401/12 , C07D215/48 , C07D215/54 , C07D215/56 , C07D219/04 , C07D219/06 , C07D219/08 , C07D221/08 , C07D333/66 , C07D333/70 , C07D401/14 , C07D471/04 , C07D491/04 , C07D495/04 , C07D513/04 , C07F7/0812
摘要： This invention provides compounds of formula 1, having the structure which are useful as inhibitors of protein tyrosine kinase and are antiproliferative agents.

89. 发明申请

US20050075357A1 5-arylpyrimidines as anticancer agents 有权
标题翻译： 5-芳基嘧啶作为抗癌剂
公开(公告)号：US20050075357A1
公开(公告)日：2005-04-07
申请号：US10950375
申请日：2004-09-24
申请人： Nan Zhang , Semiramis Ayral-Kaloustian , Thai Nguyen
发明人： Nan Zhang , Semiramis Ayral-Kaloustian , Thai Nguyen
IPC分类号： A61K31/505 , A61K31/506 , A61P35/00 , C07D239/42 , C07D239/48 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04 , A61K31/513 , C07D43/02
CPC分类号： C07D239/42 , A61K31/505 , A61K31/506 , C07D239/48 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04
摘要： This invention relates to certain 5-arylpyrimidine compounds or a pharmaceutically acceptable salt thereof, and compositions containing said compounds or a pharmaceutically acceptable salt thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or a pharmaceutically acceptable salt thereof. More specifically, the present invention relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal in need thereof by promotion of microtubule polymerization which comprises administering to said mammal an effective amount of said compounds and pharmaceutically acceptable salts thereof.
摘要翻译：本发明涉及某些5-芳基嘧啶化合物或其药学上可接受的盐，以及含有所述化合物或其药学上可接受的盐的组合物，其中所述化合物是可用于治疗哺乳动物癌症的抗癌剂。本发明还涉及治疗或抑制哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，并进一步提供了治疗或预防表达多重耐药性（MDR）或耐多药耐药性的癌性肿瘤的方法在需要的哺乳动物中，所述方法包括向所述哺乳动物施用有效量的所述化合物或其药学上可接受的盐。更具体地，本发明涉及通过促进微管聚合来治疗或抑制有需要的哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，其包括向所述哺乳动物施用有效量的所述化合物和药学上可接受的盐其中。

90. 发明授权

US06682871B2 Microelectromechanical optical switch and method of manufacture thereof 失效
标题翻译：微机电光开关及其制造方法
公开(公告)号：US06682871B2
公开(公告)日：2004-01-27
申请号：US09789887
申请日：2001-02-21
申请人： Nan Zhang
发明人： Nan Zhang
IPC分类号： G03F700
CPC分类号： G02B6/357 , B81B2201/033 , B81B2201/045 , B81C1/00182 , B81C2201/0109 , B81C2203/0136 , G02B6/3514 , G02B6/3518 , G02B6/3544 , G02B6/3584 , H02N1/008
摘要： A MEMS-based optical switch having improved characteristics and methods for manufacturing the same are provided. In accordance with one embodiment, an optical switch includes a single comb drive actuator having a deflecting beam structure and a mirror coupled to the actuator. The mirror is capable of being moved between an extended position interposed between waveguide channels and a retracted position apart from the waveguide channels. The actuator applies a force capable of deflecting the beam structure and moving the mirror to one of the extended positions or the retracted position and the beam structure returns the mirror to the other of the extended position or the retracted position in the absence of the application of force.
摘要翻译：提供了具有改进的特性的MEMS基光开关及其制造方法。根据一个实施例，光学开关包括具有偏转梁结构的单个梳状驱动致动器和耦合到致动器的反射镜。镜子能够在介于波导通道之间的延伸位置与离开波导通道的缩回位置之间移动。致动器施加能够使梁结构偏转并且将反射镜移动到延伸位置或缩回位置中的一个的力，并且梁结构在没有应用的情况下将反射镜返回到延伸位置或缩回位置中的另一个力。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式