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81. 发明授权

US08775105B2 Onboard adaptive battery core temperature estimation 有权
标题翻译：板载自适应电池核心温度估计
公开(公告)号：US08775105B2
公开(公告)日：2014-07-08
申请号：US12914245
申请日：2010-10-28
申请人： Jian Lin , Rezina S. Nabi , Gary M. Insana , Mahendra M. Kenkre , Wenbo Wang
发明人： Jian Lin , Rezina S. Nabi , Gary M. Insana , Mahendra M. Kenkre , Wenbo Wang
IPC分类号： G01R31/36 , H02J7/00 , H01M10/0525 , H01M10/48
CPC分类号： H01M10/486 , H01M10/0525 , Y02E60/122 , Y02T10/7011
摘要： Methods and systems for dynamically estimating the core temperature of at least one cell in a battery. In one aspect, the method includes using a combination of estimations including one based on ohmic resistance and another based on a function of thermal energy transfer through the battery. A weighting factor may be used for each of the estimations as a way to calculating a core temperature. The estimation based on ohmic resistance may be made determined independently of a measured surface temperature of the battery or any of the cells in the battery.
摘要翻译：用于动态估计电池中至少一个电池的核心温度的方法和系统。一方面，该方法包括基于通过电池的热能传递的功能，使用包括基于欧姆电阻的估计的组合和另一个估计的组合。对于每个估计可以使用加权因子作为计算核心温度的方式。可以独立于电池或电池中的任何电池的测量的表面温度来确定基于欧姆电阻的估计。

82. 发明授权

US08624559B2 Excessive current detection controls method 有权
标题翻译：过电流检测控制方法
公开(公告)号：US08624559B2
公开(公告)日：2014-01-07
申请号：US12904893
申请日：2010-10-14
申请人： Asif A. Syed , Andrew H. Leutheuser , Jian Lin , Joseph M. Lograsso , Roland Matthe′
发明人： Asif A. Syed , Andrew H. Leutheuser , Jian Lin , Joseph M. Lograsso , Roland Matthe′
IPC分类号： H02J7/14
CPC分类号： B60L11/1851 , H01M10/48 , H01M2220/20 , Y02T10/7011 , Y02T10/705
摘要： A method for controlling charging and discharging of a battery pack for an electric or hybrid vehicle to prevent overheating damage. Current flowing into or out of the battery pack is monitored, and root mean square (RMS) current is integrated over a time window and compared to a threshold to determine if power needs to be regulated in order to prevent damage to the cells in the battery pack. If the time-integrated RMS current exceeds the threshold, a closed-loop proportional-integral (PI) controller is activated to regulate power input or output. The controller will continue to regulate power until the time-integrated RMS current drops below the threshold. Various thresholds can be defined for different time windows. The gains used in the PI controller can also be adjusted to scale the amount of power regulation.
摘要翻译：一种用于控制用于电动或混合动力车辆的电池组的充放电的方法，以防止过热损坏。监测流入或流出电池组的电流，并且在一个时间窗口内积分均方根（RMS）电流，并将其与阈值进行比较，以确定是否需要调节功率以防止损坏电池中的电池包。如果时间积分RMS电流超过阈值，则会启用闭环比例积分（PI）控制器来调节功率输入或输出。控制器将继续调节功率，直到时间积分RMS电流降至阈值以下。可以为不同的时间窗口定义各种阈值。 PI控制器中使用的增益也可以调整以调整功率调节量。

83. 发明申请

US20130273034A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT 审中-公开
标题翻译：新型化合物和组合物抑制NAMPT
公开(公告)号：US20130273034A1
公开(公告)日：2013-10-17
申请号：US13820496
申请日：2011-09-02
申请人： Kenneth W. Bair , Timm R. Baumeister , Alexandre J. Buckmelter , Karl H. Clodfelter , Bingsong Han , Jian Lin , Dominic J. Reynolds , Chase C. Smith , Zhongguo Wang , Xiaozhang Zheng , Po-Wai Yuen
发明人： Kenneth W. Bair , Timm R. Baumeister , Alexandre J. Buckmelter , Karl H. Clodfelter , Bingsong Han , Jian Lin , Dominic J. Reynolds , Chase C. Smith , Zhongguo Wang , Xiaozhang Zheng , Po-Wai Yuen
IPC分类号： C07D401/12 , C07D213/40 , A61K31/4406 , A61K45/06 , C07D471/04 , A61K31/437 , C07D213/74 , A61K31/44 , A61K31/4545 , A61K31/5377
CPC分类号： C07D401/12 , A61K31/437 , A61K31/44 , A61K31/4406 , A61K31/4545 , A61K31/5377 , A61K45/06 , C07C317/42 , C07D213/40 , C07D213/54 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/84 , C07D471/04
摘要： The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:
摘要翻译：本发明涉及抑制NAMPT，其合成，应用和解毒剂的化合物和组合物。本发明的说明性化合物如下所示：

84. 发明授权

US08560257B2 Dynamic battery capacity estimation 有权
标题翻译：动态电池容量估算
公开(公告)号：US08560257B2
公开(公告)日：2013-10-15
申请号：US12955288
申请日：2010-11-29
申请人： Xidong Tang , Yandong Zhang , Andrew C Baughman , Brian J. Koch , Jian Lin , Damon R. Frisch
发明人： Xidong Tang , Yandong Zhang , Andrew C Baughman , Brian J. Koch , Jian Lin , Damon R. Frisch
IPC分类号： G01R31/36 , G06F19/00
CPC分类号： H01M10/48 , G01R31/3651 , G01R31/3679 , H01M10/425 , H01M10/486
摘要： A method of determining a state of health of a battery in real time includes estimating a parameter value associated with the state of health of the battery and determining one or more of a terminal voltage, an accumulated charge, a state of charge, and a temperature of the battery. The method further includes determining, via a computing device, a reserve capacity of the battery based at least in part on the estimated parameter value and one or more of the terminal voltage, the accumulated charge, the state of charge, and the temperature of the battery.
摘要翻译：实时确定电池的健康状况的方法包括估计与电池的健康状况相关联的参数值，并且确定终端电压，累积电荷，充电状态和温度中的一个或多个的电池。该方法还包括至少部分地基于所估计的参数值以及终端电压，累积电荷，充电状态和所述电池的温度中的一个或多个来经由计算设备确定电池的备用容量电池。

85. 发明申请

US20120136595A1 BATTERY DIFFUSION VOLTAGE ESTIMATION 审中-公开
标题翻译：电池扩散电压估计
公开(公告)号：US20120136595A1
公开(公告)日：2012-05-31
申请号：US13229931
申请日：2011-09-12
申请人： Xidong Tang , Jian Lin , Benjamin Thorsen , Brian J. Koch , Kurt M. Johnson
发明人： Xidong Tang , Jian Lin , Benjamin Thorsen , Brian J. Koch , Kurt M. Johnson
IPC分类号： G06F19/00
CPC分类号： H01M10/48 , B60L3/12 , B60L58/12 , B60L58/16 , B60L2240/545 , B60L2240/547 , B60L2240/549 , B60L2260/44 , H01M10/425 , Y02T10/7005 , Y02T10/7044 , Y02T10/705
摘要： A method includes estimating a first diffusion voltage value of a battery by selecting the first diffusion voltage value from a look-up table, estimating a second diffusion voltage value of the battery using an estimation procedure, selecting at least one of the estimated first and second diffusion voltage values, and determining an open circuit voltage of the battery based at least in part on the selected diffusion voltage value. The method may be implemented by a computing device in a vehicle.
摘要翻译：一种方法包括通过从查找表中选择第一扩散电压值来估计电池的第一扩散电压值，使用估计程序估计电池的第二扩散电压值，选择所估计的第一和第二扩散电压值中的至少一个扩散电压值，以及至少部分地基于所选择的扩散电压值来确定电池的开路电压。该方法可以由车辆中的计算设备来实现。

86. 发明申请

US20120109554A1 ONBOARD ADAPTIVE BATTERY CORE TEMPERATURE ESTIMATION 有权
标题翻译： ONBOARD自适应电池核心温度估算
公开(公告)号：US20120109554A1
公开(公告)日：2012-05-03
申请号：US12914245
申请日：2010-10-28
申请人： Jian Lin , Rezina S. Nabi , Gary M. Insana , Mahendra M. Kenkre , Wenbo Wang
发明人： Jian Lin , Rezina S. Nabi , Gary M. Insana , Mahendra M. Kenkre , Wenbo Wang
IPC分类号： G06F15/00 , G01R31/36 , G01K13/00
CPC分类号： H01M10/486 , H01M10/0525 , Y02E60/122 , Y02T10/7011
摘要： Methods and systems for dynamically estimating the core temperature of at least one cell in a battery. In one aspect, the method includes using a combination of estimations including one based on ohmic resistance and another based on a function of thermal energy transfer through the battery. A weighting factor may be used for each of the estimations as a way to calculating a core temperature. The estimation based on ohmic resistance may be made determined independently of a measured surface temperature of the battery or any of the cells in the battery.
摘要翻译：用于动态估计电池中至少一个电池的核心温度的方法和系统。一方面，该方法包括基于通过电池的热能传递的功能，使用包括基于欧姆电阻的估计的组合和另一个估计的组合。对于每个估计可以使用加权因子作为计算核心温度的方式。可以独立于电池或电池中的任何电池的测量的表面温度来确定基于欧姆电阻的估计。

87. 发明授权

US08131828B2 Selectively joining clients to meeting servers 有权
标题翻译：选择性地加入客户端到会议服务器
公开(公告)号：US08131828B2
公开(公告)日：2012-03-06
申请号：US12245595
申请日：2008-10-03
申请人： Jian Lin , Zheng Yuan , Weixin Xia , Yongya Wang , Sihai Xiao , Ilan Kasan
发明人： Jian Lin , Zheng Yuan , Weixin Xia , Yongya Wang , Sihai Xiao , Ilan Kasan
IPC分类号： G06F15/177 , G06F15/173 , H04L12/16 , H04N7/14
CPC分类号： H04L63/102 , H04L12/1818
摘要： In an embodiment, a hosted-on-premises meeting exchange server operates seamlessly with web meeting servers. For example, one computer-implemented method comprises receiving a request from a client computer to join a web meeting; determining whether the client computer is coupled to a local network which includes an on-premises-meeting exchange server; in response to determining that the client computer is coupled to the local network, joining the client computer to the web meeting at the on-premises-meeting exchange server when the on-premises-meeting exchange server has sufficient capacity, and otherwise joining the client computer to the web meeting at an off-premises-meeting exchange server; and in response to determining that the client computer is not coupled to the local network, joining the client computer to the web meeting at the off-premises-meeting exchange server.
摘要翻译：在一个实施例中，本地托管的会议交换服务器与web会议服务器无缝地运行。例如，一种计算机实现的方法包括从客户端计算机接收加入网络会议的请求; 确定所述客户端计算机是否耦合到包括本地会议交换服务器的本地网络; 响应于确定客户端计算机耦合到本地网络，当房内会议交换服务器具有足够的容量时，将客户端计算机加入室内会议交换服务器的网络会议，否则加入客户端计算机到室外会议交换服务器的网络会议; 并且响应于确定客户端计算机未耦合到本地网络，将客户端计算机加入到室外会议交换服务器处的网络会议。

88. 发明申请

US20110263588A1 TRICYCLIC COMPOUNDS AS GLUTAMATE RECEPTOR MODULATORS 审中-公开
标题翻译：作为谷氨酸受体调节剂的三聚化合物
公开(公告)号：US20110263588A1
公开(公告)日：2011-10-27
申请号：US13126118
申请日：2009-10-23
申请人： Peter Bertinato , Merav Fichman , Shomir Ghosh , Jian Lin , Dalia Segal , Zhaoda Zhang
发明人： Peter Bertinato , Merav Fichman , Shomir Ghosh , Jian Lin , Dalia Segal , Zhaoda Zhang
IPC分类号： A61K31/5377 , C07D471/04 , A61K31/4162 , A61K31/4439 , A61K31/437 , A61K31/454 , A61P25/28 , A61P25/14 , A61P25/22 , A61P25/24 , A61P29/00 , A61P25/06 , A61P1/04 , A61P25/34 , A61P25/00 , C07D491/052
CPC分类号： C07D491/052 , C07D231/54 , C07D471/04
摘要： The present invention relates to compounds that may be negative allosteric modulators of metabotropic receptors-subtype 5, and methods of making and using same.
摘要翻译：本发明涉及可以是代谢型受体 - 亚型5的负变构调节剂的化合物及其制备和使用方法。

89. 发明申请

US20110212940A1 S1P Receptor Modulating Compounds and Use Thereof 审中-公开
公开(公告)号：US20110212940A1
公开(公告)日：2011-09-01
申请号：US13034895
申请日：2011-02-25
申请人： Roland Burli , Victor J. Cee , Jennifer Golden , Brian Alan Lanman , Susana Neira , Ashis Saha , Nili Schutz , Xiang Yu , Dilara McCauley , Mercedes Lobera , Yael Marantz , Jian Lin , Srinivasa R. Cheruku , Pini Orbach , Anurag Sharadendu , Robert C. Penland , Kimberley Gannon , Sharon Shacham , Silvia Noiman , Oren Becker , Zhaoda Zhang
发明人： Roland Burli , Victor J. Cee , Jennifer Golden , Brian Alan Lanman , Susana Neira , Ashis Saha , Nili Schutz , Xiang Yu , Dilara McCauley , Mercedes Lobera , Yael Marantz , Jian Lin , Srinivasa R. Cheruku , Pini Orbach , Anurag Sharadendu , Robert C. Penland , Kimberley Gannon , Sharon Shacham , Silvia Noiman , Oren Becker , Zhaoda Zhang
IPC分类号： A61K31/397 , C07D405/10 , A61K31/4525 , C07D405/14 , A61K31/443 , C07D413/14 , A61K31/427 , C07D409/14 , A61K31/4725 , A61K31/4025 , C07D307/80 , A61K31/343 , A61K31/5377 , C07D413/10 , A61K31/41 , A61P35/00 , A61P37/06 , A61P29/00 , A61P3/10 , A61P25/00 , A61P17/06 , A61P35/02 , A61P11/00 , A61P11/06 , A61P17/02 , A61P9/00 , A61P9/10 , A61P13/12 , A61P1/16 , A61P7/06
CPC分类号： C07D307/79 , C07D307/80 , C07D307/81 , C07D403/10 , C07D405/04 , C07D405/10 , C07D405/14 , C07D409/14 , C07D413/10 , C07D413/14 , C07D417/10 , C07D417/14 , C07D471/04 , C07D491/048
摘要： The present invention relates to compounds of the general formula (I) that have activity as S1P receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds may be used as immunomodulators, e.g., for treating or preventing diseases such as autoimmune and related immune disorders including systemic lupus erythematosus, inflammatory bowel diseases such as Crohn's disease and ulcerative colitis, type I diabetes, uveitis, psoriasis, myasthenia gravis, rheumatoid arthritis, non-glomerular nephrosis, hepatitis, Behçet's disease, glomerulonephritis, chronic thrombocytopenic purpura, hemolytic anemia, hepatitis and Wegner's granuloma; and for treating other conditions.

90. 发明授权

US07919519B2 S1P receptor modulating compounds and use thereof 失效
标题翻译： S1P受体调节化合物及其用途
公开(公告)号：US07919519B2
公开(公告)日：2011-04-05
申请号：US11726351
申请日：2007-03-21
申请人： Roland Burli , Victor J. Cee , Jennifer Golden , Brian Alan Lanman , Susana Neira , Ashis Saha , Nili Schutz , Xiang Yu , Dilara McCauley , Mercedes Lobera , Yael Marantz , Jian Lin , Srinivasa R. Cheruku , Pini Orbach , Anurag Sharadendu , Robert C. Penland , Kimberley Gannon , Sharon Shacham , Silvia Noiman , Oren Becker , Zhaoda Zhang
发明人： Roland Burli , Victor J. Cee , Jennifer Golden , Brian Alan Lanman , Susana Neira , Ashis Saha , Nili Schutz , Xiang Yu , Dilara McCauley , Mercedes Lobera , Yael Marantz , Jian Lin , Srinivasa R. Cheruku , Pini Orbach , Anurag Sharadendu , Robert C. Penland , Kimberley Gannon , Sharon Shacham , Silvia Noiman , Oren Becker , Zhaoda Zhang
IPC分类号： A61K31/404 , A61K31/381 , A61K31/343 , C07D209/12 , C07D333/56 , C07D307/80
CPC分类号： C07D307/79 , C07D307/80 , C07D307/81 , C07D403/10 , C07D405/04 , C07D405/10 , C07D405/14 , C07D409/14 , C07D413/10 , C07D413/14 , C07D417/10 , C07D417/14 , C07D471/04 , C07D491/048
摘要： The present invention relates to compounds of the general formula (I) that have activity as S1P receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds may be used as immunomodulators, e.g., for treating or preventing diseases such as autoimmune and related immune disorders including systemic lupus erythematosus, inflammatory bowel diseases such as Crohn's disease and ulcerative colitis, type I diabetes, uveitis, psoriasis, myasthenia gravis, rheumatoid arthritis, non-glomerular nephrosis, hepatitis, Behçet's disease, glomerulonephritis, chronic thrombocytopenic purpura, hemolytic anemia, hepatitis and Wegner's granuloma; and for treating other conditions.
摘要翻译：本发明涉及具有作为S1P受体调节剂的活性的通式（I）的化合物，以及这些化合物用于治疗与不适当的S1P受体活性有关的疾病的用途。这些化合物可用作免疫调节剂，例如用于治疗或预防诸如自身免疫性疾病和相关免疫疾病（包括系统性红斑狼疮），炎症性肠病如克罗恩病和溃疡性结肠炎，I型糖尿病，葡萄膜炎，牛皮癣，重症肌无力，类风湿关节炎，非肾小球性肾病，肝炎，白塞病，肾小球性肾炎，慢性血小板减少性紫癜，溶血性贫血，肝炎和韦格纳肉芽肿; 并处理其他条件。

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