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81. 发明申请

US20080131932A1 EXPRESSION IN FILAMENTOUS FUNGI OF PROTEASE INHIBITORS AND VARIANTS THEREOF 有权
公开(公告)号：US20080131932A1
公开(公告)日：2008-06-05
申请号：US11848213
申请日：2007-08-30
申请人： Hans De Nobel , David A. Estell , Wei Liu , Scott D. Power , Brian Schmidt , Huaming Wang
发明人： Hans De Nobel , David A. Estell , Wei Liu , Scott D. Power , Brian Schmidt , Huaming Wang
IPC分类号： C07H21/04 , C12P1/00 , C12N15/00 , C12N15/74 , C12N5/02 , C12P21/04
CPC分类号： C12N15/80 , C07K14/811
摘要： Described herein are protease inhibitors, variants thereof and methods for their production.

82. 发明申请

US20080122228A1 Method, apparatus, signals and media, for selecting operating conditions of a genset 有权
标题翻译：用于选择发电机组的运行条件的方法，装置，信号和介质
公开(公告)号：US20080122228A1
公开(公告)日：2008-05-29
申请号：US11821855
申请日：2007-06-26
申请人： Wei Liu , Nicolas Louis Bouchon
发明人： Wei Liu , Nicolas Louis Bouchon
IPC分类号： G01R11/56 , H02P9/04 , F02D35/00 , G06F17/00 , H02J7/14 , B60W20/00
CPC分类号： B60W20/11 , B60K6/48 , B60L1/003 , B60L1/02 , B60L3/0023 , B60L11/005 , B60L11/02 , B60L11/126 , B60L11/16 , B60L15/2045 , B60L2240/36 , B60L2240/421 , B60L2240/441 , B60W10/06 , B60W10/08 , B60W10/24 , B60W20/00 , B60W20/10 , B60W20/15 , B60W20/16 , B60W2510/06 , B60W2530/14 , F01N11/00 , G01F13/00 , G01N19/00 , G06F15/00 , H02P9/04 , Y02T10/47 , Y02T10/56 , Y02T10/6217 , Y02T10/6221 , Y02T10/645 , Y02T10/7005 , Y02T10/7022 , Y02T10/7077 , Y02T10/72 , Y02T10/7283 , Y10S903/902 , Y10S903/903 , Y10S903/905 , Y10S903/906 , Y10S903/93
摘要： A method and apparatus for selecting optimal operating conditions of a genset is disclosed. The genset includes an engine coupled to an electrical power generator, the genset having a plurality of operating points each including an engine speed value and a generator electrical power output value, and having a plurality of cost values associated with operating the genset at respective operating points. The method involves selecting a set of operating points from the plurality of operating points such that a sum of cost values associated with operating points in the set is minimized and such that the engine speed and generator electrical power output values of the operating points in the set increase or decrease monotonically.
摘要翻译：公开了一种用于选择发电机组的最佳操作条件的方法和装置。发电机组包括联接到发电机的发动机，发电机组具有多个工作点，每个工作点包括发动机速度值和发电机电功率输出值，并且具有与在相应工作点操作发电机组相关联的多个成本值。该方法包括从多个操作点中选择一组操作点，使得与组中的操作点相关联的成本值的总和最小化，并且使得该组中的操作点的发动机速度和发电机电功率输出值增加或减少单调。

83. 发明申请

US20080071504A1 LIBRARY ACCURACY ENHANCMENT AND EVALUATION 失效
标题翻译：图书馆精确度增强与评估
公开(公告)号：US20080071504A1
公开(公告)日：2008-03-20
申请号：US11946821
申请日：2007-11-28
申请人： Shifang Li , Junwei Bao , Wei Liu
发明人： Shifang Li , Junwei Bao , Wei Liu
IPC分类号： G06F15/00
CPC分类号： G01B11/24 , G03F7/70625
摘要： The accuracy of a library of simulated-diffraction signals for use in optical metrology of a structure formed on a wafer is evaluated by utilizing an identity relationship inherent to simulated diffraction signals. Each simulated diffraction signal contains at least one set of four reflectivity parameters for a wavelength and/or angle of incidence. One of the four reflectivity parameters is selected. A value for the selected reflectivity parameter is determined using the identity relationship and values of the remaining three reflectivity parameters. The determined value for the selected reflectivity parameter is compared to the value in the obtained set of four reflectivity parameters to evaluate and improve the accuracy of the library. The identity relationship can also be used to reduce the data storage in a library.
摘要翻译：通过利用模拟衍射信号固有的身份关系来评估用于在晶片上形成的结构的光学计量学中的模拟衍射信号库的精度。每个模拟衍射信号包含用于波长和/或入射角的至少一组四个反射率参数。选择四个反射率参数之一。使用身份关系和剩余的三个反射率参数的值确定所选反射率参数的值。将所选反射率参数的确定值与获得的四个反射率参数组中的值进行比较，以评估和提高库的准确性。身份关系也可用于减少库中的数据存储。

84. 发明申请

US20080013107A1 Generating a profile model to characterize a structure to be examined using optical metrology 审中-公开
标题翻译：使用光学计量产生轮廓模型来表征要检查的结构
公开(公告)号：US20080013107A1
公开(公告)日：2008-01-17
申请号：US11484974
申请日：2006-07-11
申请人： Jeffrey A. Chard , Junwei Bao , Joerg Bischoff , Shifang Li , Wei Liu , Hong Qiu , Sylvio Rabello , Vi Vuong
发明人： Jeffrey A. Chard , Junwei Bao , Joerg Bischoff , Shifang Li , Wei Liu , Hong Qiu , Sylvio Rabello , Vi Vuong
IPC分类号： G01B11/14
CPC分类号： G01B11/24 , G01N21/4788 , G01N21/95607 , G01N2021/8883 , G01N2021/95615
摘要： In generating a profile model to characterize a structure to be examined using optical metrology, a view canvas is displayed, with the profile model being generated displayed in the view canvas. A profile shape palette is displayed adjacent to the view canvas. A plurality of different profile shape primitives is displayed in the profile shape palette. Each profile shape primitive in the profile shape palette is defined by a set of profile parameters. When a user selects a profile shape primitive from the profile shape palette, drags the selected profile shape primitive from the profile shape palette, and drops the selected profile shape primitive into the view canvas, the selected profile shape primitive is incorporated into the profile model being generated and displayed in the view canvas.
摘要翻译：在生成轮廓模型以使用光学计量学来表征要检查的结构时，显示视图画布，其中生成的轮廓模型显示在视图画布中。在视图画布附近显示一个轮廓形状调色板。在轮廓形状调色板中显示多个不同的轮廓形状基元。轮廓形状调色板中的每个轮廓形状基元由一组轮廓参数定义。当用户从轮廓形状调色板中选择轮廓形状基元时，从轮廓形状调色板中拖动所选择的轮廓形状基元，并将所选择的轮廓形状基元拖放到视图画布中，将所选择的轮廓形状原语合并到轮廓模型中生成并显示在视图画布中。

85. 发明授权

US07297525B2 Composition employing a novel human kinase 失效
标题翻译：使用新的人类激酶的组合物
公开(公告)号：US07297525B2
公开(公告)日：2007-11-20
申请号：US10702496
申请日：2003-11-07
申请人： Wei Liu , Leeying Wu , Huimin Chen
发明人： Wei Liu , Leeying Wu , Huimin Chen
IPC分类号： C12N9/12 , C12N15/54
CPC分类号： C12N9/1205
摘要： This invention provides compositions, organisms and methodologies employing a novel human protein kinase, MCRK1. The novel human kinase has sequence homology to rat myotonic dystrophy kinase-related Cdc42 binding kinase (MRCK) alpha. The gene encoding the novel kinase is localized in locus 11q13 of human chromosome 11. The novel protein kinase comprises multiple functional/structural domains that include a kinase domain, a pkinase_C domain, a DAG-PE binding domain, and a CNH domain. The sequence and structure similarity between the novel human protein and rat MRCK alpha indicates that the novel human protein may function as a downstream effector of Cdc42 in cytoskeleton reorganization.
摘要翻译：本发明提供了使用新型人蛋白激酶MCRK1的组合物，生物体和方法。新型人类激酶与大鼠肌强直性营养不良激酶相关的Cdc42结合激酶（MRCK）α具有序列同源性。编码新型激酶的基因位于人染色体11的位点11q13中。新型蛋白激酶包含多个功能/结构域，其包括激酶结构域，pkinase_C结构域，DAG-PE结合结构域和CNH结构域。新型人类蛋白质与大鼠MRCKα之间的序列和结构相似性表明新型人类蛋白质可能在细胞骨架重组中起到Cdc42的下游作用。

86. 发明申请

US20070225940A1 Library accuracy enhancement and evaluation 有权
标题翻译：图书馆精确度增强和评估
公开(公告)号：US20070225940A1
公开(公告)日：2007-09-27
申请号：US11390798
申请日：2006-03-27
申请人： Shifang Li , Junwei Bao , Wei Liu
发明人： Shifang Li , Junwei Bao , Wei Liu
IPC分类号： G06F19/00
CPC分类号： G01B11/24 , G03F7/70625
摘要： The accuracy of a library of simulated-diffraction signals for use in optical metrology of a structure formed on a wafer is evaluated by utilizing an identity relationship inherent to simulated diffraction signals. Each simulated diffraction signal contains at least one set of four reflectivity parameters for a wavelength and/or angle of incidence. One of the four reflectivity parameters is selected. A value for the selected reflectivity parameter is determined using the identity relationship and values of the remaining three reflectivity parameters. The determined value for the selected reflectivity parameter is compared to the value in the obtained set of four reflectivity parameters to evaluate and improve the accuracy of the library. The identity relationship can also be used to reduce the data storage in a library.
摘要翻译：通过利用模拟衍射信号固有的身份关系来评估用于在晶片上形成的结构的光学计量学中的模拟衍射信号库的精度。每个模拟衍射信号包含用于波长和/或入射角的至少一组四个反射率参数。选择四个反射率参数之一。使用身份关系和剩余的三个反射率参数的值确定所选反射率参数的值。将所选反射率参数的确定值与获得的四个反射率参数组中的值进行比较，以评估和提高库的准确性。身份关系也可用于减少库中的数据存储。

87. 发明授权

US07269669B2 Sharing single host controller with multiple functional devices 失效
标题翻译：与多个功能设备共享单个主机控制器
公开(公告)号：US07269669B2
公开(公告)日：2007-09-11
申请号：US10885941
申请日：2004-07-07
申请人： Wei Liu , Feng Mo , Kunquan Sun , Yanbing Yu , Yujie Zhu
发明人： Wei Liu , Feng Mo , Kunquan Sun , Yanbing Yu , Yujie Zhu
IPC分类号： G06F13/14
CPC分类号： G06F13/4022 , G06F13/385
摘要： Multi-media Memory Card (MMC) devices, Secure Digital (SD) devices, and Secure Digital Input Output (SDIO) devices connected to a single host controller with signals multiplexed to allow simultaneous activation of more than one device at a time.
摘要翻译：多媒体存储卡（MMC）设备，安全数字（SD）设备和连接到单个主机控制器的安全数字输入输出（SDIO）设备，多路复用信号，以允许同时激活多个设备。

88. 发明申请

US20070202700A1 Etch methods to form anisotropic features for high aspect ratio applications 审中-公开
标题翻译：蚀刻方法来形成高纵横比应用的各向异性特征
公开(公告)号：US20070202700A1
公开(公告)日：2007-08-30
申请号：US11363789
申请日：2006-02-27
申请人： Uwe Leucke , Meihua Shen , Guangxiang Jin , Xikun Wang , Wei Liu , Scott Williams
发明人： Uwe Leucke , Meihua Shen , Guangxiang Jin , Xikun Wang , Wei Liu , Scott Williams
IPC分类号： H01L21/302 , C23F1/00
CPC分类号： C23F4/00 , H01L21/3065 , H01L21/3086 , H01L21/31116 , H01L21/31122 , H01L21/32136 , H01L21/32137 , H01L21/32139
摘要： Methods for forming anisotropic features for high aspect ratio application in etch process are provided in the present invention. The methods described herein advantageously facilitates profile and dimension control of features with high aspect ratios through a sidewall passivation management scheme. In one embodiment, sidewall passivations are managed by selectively forming an oxidation passivation layer on the sidewall and/or bottom of etched layers. In another embodiment, sidewall passivation is managed by periodically clearing the overburden redeposition layer to preserve an even and uniform passivation layer thereon. The even and uniform passivation allows the features with high aspect ratios to be incrementally etched in a manner that pertains a desired depth and vertical profile of critical dimension in both high and low feature density regions on the substrate without generating defects and/or overetching the underneath layers.
摘要翻译：在本发明中提供了用于在蚀刻工艺中形成用于高纵横比应用的各向异性特征的方法。本文描述的方法通过侧壁钝化管理方案有利地促进具有高纵横比的特征的轮廓和尺寸控制。在一个实施例中，通过在蚀刻层的侧壁和/或底部选择性地形成氧化钝化层来管理侧壁钝化。在另一个实施例中，通过周期性地清除覆盖层再沉积层以在其上保持均匀且均匀的钝化层来管理侧壁钝化。均匀和均匀的钝化允许以在衬底上的高和低特征密度区域中具有临界尺寸的期望深度和垂直分布的方式来逐渐蚀刻具有高纵横比的特征，而不产生缺陷和/或过蚀刻下面层。

89. 发明申请

US20070199922A1 Etch methods to form anisotropic features for high aspect ratio applications 失效
公开(公告)号：US20070199922A1
公开(公告)日：2007-08-30
申请号：US11363834
申请日：2006-02-27
申请人： Meihua Shen , Uwe Leucke , Guangxiang Jin , Xikun Wang , Wei Liu , Scott Williams
发明人： Meihua Shen , Uwe Leucke , Guangxiang Jin , Xikun Wang , Wei Liu , Scott Williams
IPC分类号： H01L21/461 , B44C1/22 , H01L21/302
CPC分类号： H01L21/76802 , H01L21/32137 , H01L21/76814
摘要： Methods for forming anisotropic features for high aspect ratio application in etch process are provided in the present invention. The methods described herein advantageously facilitates profile and dimension control of features with high aspect ratios through a sidewall passivation management scheme. In one embodiment, sidewall passivations are managed by selectively forming an oxidation passivation layer on the sidewall and/or bottom of etched layers. In another embodiment, sidewall passivation is managed by periodically clearing the overburden redeposition layer to preserve an even and uniform passivation layer thereon. The even and uniform passivation allows the features with high aspect ratios to be incrementally etched in a manner that pertains a desired depth and vertical profile of critical dimension in both high and low feature density regions on the substrate without generating defects and/or overetching the underneath layers.

90. 发明申请

US20070092529A1 Compositions and methods for diagnosing and treating cancers 审中-公开
标题翻译：用于诊断和治疗癌症的组合物和方法
公开(公告)号：US20070092529A1
公开(公告)日：2007-04-26
申请号：US11509413
申请日：2006-08-23
申请人： Xiaobing Be , Wei Liu , Donna Slonim , Steve Howes
发明人： Xiaobing Be , Wei Liu , Donna Slonim , Steve Howes
IPC分类号： A61K48/00 , C12Q1/68 , G01N33/574 , C07H21/04 , A61K39/00 , C12P21/06 , C07K14/82 , C07K16/30
CPC分类号： A61K31/7088 , A61K31/713 , A61K35/17 , A61K38/00 , A61K39/00 , C07K14/705 , C12N15/1138 , C12N2310/11 , C12N2310/14 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , C12Q2600/178 , G01N33/57492
摘要： Compositions and methods for diagnosing, monitoring, or treating cancers. Genes encoding transmembrane proteins that are over-expressed in colon, lung, breast, prostate, liver, stomach, esophagus, or kidney cancer tissues are identified. These transmembrane genes can be used as biological markers for the detection or diagnosis of cancers. These genes can also serve as targets for cancer therapeutics. In addition, these genes can also be used for screening for anti-cancer drugs.
摘要翻译：用于诊断，监测或治疗癌症的组合物和方法。鉴定编码在结肠，肺，乳腺，前列腺，肝，胃，食管或肾癌组织中过度表达的跨膜蛋白的基因。这些跨膜基因可以用作癌症的检测或诊断的生物学标记物。这些基因也可以作为癌症治疗的靶标。此外，这些基因也可用于筛选抗癌药物。

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