专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明授权

US5417714A DDI pacing with PVC-protected hysteresis and automatic AV interval adjustment 失效
标题翻译： DDI起搏带有PVC保护滞后和自动AV间隔调整
公开(公告)号：US5417714A
公开(公告)日：1995-05-23
申请号：US60765
申请日：1993-05-11
申请人： Paul A. Levine , Malcolm Clarke , John W. Poore , Jason A. Sholder
发明人： Paul A. Levine , Malcolm Clarke , John W. Poore , Jason A. Sholder
IPC分类号： A61N1/365 , A61N1/362 , A61N1/368 , A61N1/36
CPC分类号： A61N1/368 , A61N1/3622 , A61N1/3682
摘要： A dual-chamber pacemaker provides DDI pacing with PVC-protected hysteresis and automatic AV interval adjustment. An extended hysteresis atrial escape interval (AEI.sub.H) is invoked in response to the occurrence of either an atrial paced event followed by a sensed R-wave (an AR event), or an atrial sensed event followed by a sensed R-wave (a PR event). The occurrence of a premature ventricular contraction (PVC) thus does not trigger AEI.sub.H. In one embodiment, AEI.sub.H is not invoked unless the sensed AR or PR interval exceeds a prescribed reference interval. In a further embodiment, the AV interval (AVI) associated with the DDI operation is automatically shortened following an atrial stimulation pulse (A-pulse) delivered upon the timing-out of the AEI.sub.H. The shortened AVI is maintained for a programmed number of cycles of DDI operation, after which a lengthened AVI is reestablished for one cycle. If AV pacing follows after using the lengthened AVI, then the shortened AVI is reinstated for a second number of programmed cycles of DDI operation. If AR pacing follows after using the lengthened AVI, signifying intact AV nodal conduction, then the AVI is lengthened to the programmed AVI over a prescribed number of cycles.
摘要翻译：双室心脏起搏器为DDI起搏提供PVC保护的滞后和自动AV间隔调整。响应于发生心房起搏事件，随后是感测到的R波（AR事件）或心房感测事件，随后是感测的R波（PR），调节延长的心房逸出间隔时间（AEIH）事件）。因此早期心室收缩（PVC）的发生不会引发AEIH。在一个实施例中，除非感测到的AR或PR间隔超过规定的参考间隔，否则AEIH不被调用。在另一个实施例中，在AEIH超时之后递送的心房刺激脉冲（A脉冲）之后，与DDI操作相关联的AV间隔（AVI）自动缩短。缩短的AVI维持编程的DDI操作周期数，之后延长的AVI重新建立一个周期。如果在使用延长的AVI之后进行AV起搏，则缩短的AVI将恢复DDI操作的第二个编程周期数。如果在使用延长的AVI后进行AR起搏，则表示完整的AV节点传导，则AVI在规定数量的周期内延长到编程的AVI。

82. 发明授权

US08694082B2 Method and system for detecting and treating junctional rhythms 有权
标题翻译：连接节律的检测和处理方法和系统
公开(公告)号：US08694082B2
公开(公告)日：2014-04-08
申请号：US12727130
申请日：2010-03-18
申请人： Xing Pei , Paul A. Levine
发明人： Xing Pei , Paul A. Levine
IPC分类号： A61B5/0452
CPC分类号： A61N1/3621 , A61B5/0422 , A61B5/044 , A61B5/0452 , A61N1/36507 , A61N1/36521 , A61N1/37211
摘要： An implantable medical device is provided for detecting transportless ventricular rhythm of a heart lacking atrial transport and comprises a housing, sensors configured to be located proximate to a heart, a sensing module to sense cardiac signals representative of a rhythm originating from the heart and a rhythm detection module. The rhythm detection module determines a change in AV association and identifies a potential ventricular complex with loss of atrial transport (VCLAT) based on the change in AV association.
摘要翻译：提供了一种可植入医疗装置，用于检测缺乏心房输送的心脏的无运动心室节律，并且包括壳体，被配置为邻近心脏定位的传感器，感测模块，用于感测代表源自心脏的节律的心脏信号和节律检测模块。节律检测模块基于AV关联的变化来确定AV关联的变化并识别具有心房传播丧失（VCLAT）的潜在心室复合体。

83. 发明授权

US07986993B1 Implantable cardiac device providing AV interval hysteresis to promote intrinsic conduction while providing PMT avoidance and method 有权
标题翻译：植入式心脏装置提供AV间隔滞后，以提供内在传导，同时提供PMT回避和方法
公开(公告)号：US07986993B1
公开(公告)日：2011-07-26
申请号：US11769602
申请日：2007-06-27
申请人： Paul A. Levine
发明人： Paul A. Levine
IPC分类号： A61N1/18
CPC分类号： A61N1/37 , A61N1/3622 , A61N1/3682
摘要： An implantable cardiac stimulation device provides AV interval hysteresis to promote intrinsic conduction while providing PMT avoidance. The device comprises a pulse generator that provides atrial and ventricular pacing stimulation pulses on demand separated by an AV interval, an AV hysteresis circuit that extends the AV interval from a base AV interval to an extended AV interval to promote intrinsic heart activity, and a refractory circuit that establishes a PVARP following each provided ventricular pacing pulse including a lengthened PVARP longer in duration than a normal PVARP responsive to the AV hysteresis circuit extending the AV interval from the base AV interval to the extended AV interval.
摘要翻译：植入式心脏刺激装置提供AV间隔滞后以促进固有传导，同时提供PMT避免。所述装置包括：脉冲发生器，其根据需要由AV间隔分开提供心房和心室起搏刺激脉冲; AV滞后电路，其将AV间隔从基本AV间隔延伸到延伸的AV间隔以促进内在的心脏活动;以及耐火材料电路，其在每个提供的心室起搏脉冲之后建立PVARP，其包括延长的PVARP，其持续时间长于正常PVARP，所述PVARP响应于将AV间隔从基本AV间隔延伸到扩展AV间隔的AV滞后电路。

84. 发明申请

US20100152806A1 SYSTEMS AND METHODS FOR OPERATING AN IMPLANTABLE DEVICE FOR MEDICAL PROCEDURES 有权
标题翻译：用于操作医疗程序的可植入设备的系统和方法
公开(公告)号：US20100152806A1
公开(公告)日：2010-06-17
申请号：US12332768
申请日：2008-12-11
申请人： Paul A. Levine , Eliot L. Ostrow
发明人： Paul A. Levine , Eliot L. Ostrow
IPC分类号： A61N1/00
CPC分类号： A61N1/37 , A61N1/3688 , A61N1/3718 , A61N1/37211
摘要： When a medical procedure is performed on a patient in whom an implantable medical device is implanted, the medical procedure may have undesired effects on the medical device, such as triggering a response that initiates therapy by the device that is unnecessary and potentially dangerous to the patient. Systems and methods may facilitate performing of such medical procedures on such patients by temporarily reprogramming the medical device, monitoring for one or more detectable characteristics associated with the medical procedure to be performed, and restoring normal programming of the device based on detection and/or lack of detection of the detectable characteristic(s).
摘要翻译：当对植入了可植入医疗装置的患者执行医疗程序时，医疗程序可能对医疗装置具有不期望的影响，例如触发由该装置引起对患者不必要和潜在危险的治疗的响应。系统和方法可以通过临时重新编程医疗装置，监测与要执行的医疗程序相关联的一个或多个可检测特性，以及基于检测和/或缺乏恢复装置的正常编程来促进对这些患者的这种医疗程序的执行检测可检测特性。

85. 发明申请

US20090005828A1 IMPLANTABLE MEDICAL DEVICE FOR IDENTIFYING AND MANAGING INTRINSIC REENTRANT TACHYCARDIA 有权
标题翻译：用于识别和管理内在感染的TACHYCARDIA的可植入医疗装置
公开(公告)号：US20090005828A1
公开(公告)日：2009-01-01
申请号：US12144351
申请日：2008-06-23
申请人： Paul A. Levine
发明人： Paul A. Levine
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61N1/3956
摘要： An implantable medical device is provided that comprises a pulse generator that provides atrial and ventricular pacing pulses on demand. The pulse generator times delivery of the ventricular pacing pulses based on an AV pacing interval. The device also includes an AV hysteresis module that extends the AV interval from a base AV interval to an extended AV interval to promote intrinsic heart activity. A refractory module establishes a PVARP interval equal to base PVARP interval following at least one of the ventricular pacing pulses. The refractory module lengthens the PVARP interval by adding a PVARP extension to a base PVARP interval to provide an extended PVARP interval. The device further includes a reentrant conduction detector that identifies an intrinsic reentrant tachycardia having a retrograde P wave occurring during the PVARP extension, based on one or more of i) a retrograde P wave, ii) intrinsic R waves sensed over N cardiac cycles at an R to R interval above a rate threshold and iii) one or more of PR and RP intervals that exceed PR and RP thresholds.
摘要翻译：提供了一种植入式医疗装置，其包括根据需要提供心房和心室起搏脉冲的脉冲发生器。脉冲发生器根据AV起搏间隔来递送心室起搏脉冲。该装置还包括AV滞后模块，其将AV间隔从基本AV间隔延伸到扩展AV间隔以促进内在心脏活动。耐火模块建立等于心室起搏脉冲之后的至少一个的PVARP间隔的PVARP间隔。耐火模块通过将PVARP扩展添加到基本PVARP间隔来延长PVARP间隔，以提供扩展的PVARP间隔。该装置还包括可重入传导检测器，其基于i）逆行P波中的一个或多个来识别具有在PVARP延伸期间发生的逆行P波的本征性重入性心动过速，ii）在N个心动周期中感测到的内在R波， R到R间隔高于速率阈值，以及iii）超过PR和RP阈值的PR和RP间隔中的一个或多个。

86. 发明授权

US07272438B2 Mode switching heart stimulation apparatus and method 有权
标题翻译：模式切换心脏刺激装置及方法
公开(公告)号：US07272438B2
公开(公告)日：2007-09-18
申请号：US10964226
申请日：2004-10-12
申请人： Mark W. Kroll , Paul A. Levine
发明人： Mark W. Kroll , Paul A. Levine
IPC分类号： A61B5/0464
CPC分类号： A61N1/3622
摘要： In a heart stimulation device a mode of operation is switched in response to detection of atrial tachyarrhythmia such as atrial fibrillation. The stimulation device may initially operate in a normal mode of pacing then, upon detection of atrial tachyarrhythmia, the stimulation device may change how it senses signals and it may switch to another mode of pacing at one or more sites in the ventricle.
摘要翻译：在心脏刺激装置中，响应于房颤如心房颤动的心房快速性心律失常的检测而切换手术模式。刺激装置可以起初以正常的起搏方式进行操作，然后，在检测到心房快速性心律失常时，刺激装置可以改变其如何感测信号，并且可以切换到心室中一个或多个部位的另一种起搏模式。

87. 发明授权

US07248925B2 System and method for determining optimal atrioventricular delay based on intrinsic conduction delays 有权
标题翻译：基于内在传导延迟确定最佳房室延迟的系统和方法
公开(公告)号：US07248925B2
公开(公告)日：2007-07-24
申请号：US10928586
申请日：2004-08-27
申请人： Ken Bruhns , Xiaoyi Min , Paul A. Levine , Euljoon Park
发明人： Ken Bruhns , Xiaoyi Min , Paul A. Levine , Euljoon Park
IPC分类号： A61N1/36
CPC分类号： A61N1/3627 , A61N1/3682
摘要： A system and method for estimating optimal atrioventricular delay values for use in pacing the ventricles. Both the intrinsic inter-atrial conduction delay and the intrinsic atrioventricular conduction delay are determined for the patient and then the preferred atrioventricular pacing delay is derived therefrom. By taking into account intrinsic inter-atrial delay along with intrinsic atrioventricular delay, a more reliable estimate of the true optimal atrioventricular delay values for the patient can be achieved than with techniques that only take into account intrinsic atrioventricular delay values. In one example, the technique uses intracardiac electrogram (IEGM) signals and surface electrocardiogram (EKG) signals and hence can be performed by an external programmer without requiring Doppler echocardiography or other cardiac performance monitoring techniques. In another example, wherein the implanted device is equipped with a coronary sinus lead, the technique uses only IEGM signals and hence can be performed by the device itself.
摘要翻译：用于估计用于起搏心室的最佳房室延迟值的系统和方法。对于患者确定内在的心房传导延迟和内在的房室传导延迟，然后从其导出优选的房室起搏延迟。通过考虑内在的心房延迟以及内在的房室延迟，可以实现比仅考虑内在房室延迟值的技术更可靠的估计患者的真正最佳房室延迟值。在一个示例中，该技术使用心内电描记图（IEGM）信号和表面心电图（EKG）信号，因此可以由外部编程器执行，而不需要多普勒超声心动图或其他心脏监测技术。在另一示例中，其中植入的装置配备有冠状窦引线，该技术仅使用IEGM信号，因此可以由装置本身执行。

88. 发明授权

US07225020B1 System and method for providing preventive overdrive pacing and antitachycardia pacing using an implantable cardiac stimulation device 失效
标题翻译：使用可植入心脏刺激装置提供预防性超速起搏和抗心动过速起搏的系统和方法
公开(公告)号：US07225020B1
公开(公告)日：2007-05-29
申请号：US10657963
申请日：2003-09-08
申请人： Mark W. Kroll , Eric Falkenberg , Paul A. Levine
发明人： Mark W. Kroll , Eric Falkenberg , Paul A. Levine
IPC分类号： A61N1/05
CPC分类号： A61N1/3622 , A61N1/3627 , A61N1/3682 , A61N1/3714 , A61N1/3956 , A61N2001/0585
摘要： Techniques for enabling both preventive overdrive pacing and antitachycardia pacing (ATP) within an implantable device are provided. The device gains the benefits of overdrive pacing for preventing the onset of a tachycardia and, if one nevertheless occurs, ATP is employed to terminate the tachycardia. In particular, a technique is provided for promptly detecting the onset of atrial tachycardia during preventive overdrive pacing based on loss of capture of atrial pacing pulses. A technique is also provided for using detection of loss of capture of atrial or ventricular pacing pulses to trigger automatic switching from overdrive pacing to ATP. A setup technique determines whether to enable the automatic switching from overdrive pacing to ATP within a particular patient. Also, techniques are provided for verifying loss of capture of atrial or ventricular backup pacing pulses and for detecting low amplitude ventricular fibrillation based on loss of capture of ventricular backup pacing pulses.
摘要翻译：提供了在植入式装置内实现预防性超速起搏和抗心动过速起搏（ATP）的技术。该装置获得超速起搏的好处，以防止心动过速的发作，并且如果仍然发生，则使用ATP来终止心动过速。特别地，提供了一种技术，用于基于心房起搏脉冲的捕获损失，在预防性超速起搏中及时检测心房心动过速的发生。还提供了一种技术，用于检测心房或心室起搏脉冲的捕获损失，以触发从过速起搏到ATP的自动切换。设置技术确定是否启用在特定患者内从过速起搏到ATP的自动切换。此外，提供了用于验证心房或心室起搏脉冲的捕获损失的技术，并且用于基于心室起搏脉冲捕获的丧失来检测低振幅心室颤动。

89. 发明授权

US07212855B1 System and method for providing preventive overdrive pacing and antitachycardia pacing using an implantable cardiac stimulation device 失效
公开(公告)号：US07212855B1
公开(公告)日：2007-05-01
申请号：US10657878
申请日：2003-09-08
申请人： Mark W. Kroll , Eric Falkenberg , Paul A. Levine
发明人： Mark W. Kroll , Eric Falkenberg , Paul A. Levine
IPC分类号： A61N1/05
CPC分类号： A61N1/3622 , A61N1/3712 , A61N1/3714
摘要： Techniques for enabling both preventive overdrive pacing and antitachycardia pacing (ATP) within an implantable device are provided. The device gains the benefits of overdrive pacing for preventing the onset of a tachycardia and, if one nevertheless occurs, ATP is employed to terminate the tachycardia. In particular, a technique is provided for promptly detecting the onset of atrial tachycardia during preventive overdrive pacing based on loss of capture of atrial pacing pulses. A technique is also provided for using detection of loss of capture of atrial or ventricular pacing pulses to trigger automatic switching from overdrive pacing to ATP. A setup technique determines whether to enable the automatic switching from overdrive pacing to ATP within a particular patient. Also, techniques are provided for verifying loss of capture of atrial or ventricular backup pacing pulses and for detecting low amplitude ventricular fibrillation based on loss of capture of ventricular backup pacing pulses.

90. 发明授权

US07164944B1 Analgesic therapy for ICD patients 有权
标题翻译： ICD患者镇痛治疗
公开(公告)号：US07164944B1
公开(公告)日：2007-01-16
申请号：US10417477
申请日：2003-04-15
申请人： Mark W. Kroll , Eric Falkenberg , Paul A. Levine
发明人： Mark W. Kroll , Eric Falkenberg , Paul A. Levine
IPC分类号： A61N1/00
CPC分类号： A61N1/3962 , A61N1/36071
摘要： An exemplary method includes delivering a therapy selected from tiered therapies that include cardioversion and/or defibrillation therapies wherein the delivered therapy aims to treat a cardiac condition, delivering analgesic stimulation, determining whether the delivered therapy successfully treated the cardiac condition, and responsive to the determining, changing one or more analgesic stimulation parameters. Various other exemplary methods and/or devices capable of performing such methods are also disclosed.
摘要翻译：示例性方法包括递送选自包括心脏复律和/或除颤疗法的分层治疗的治疗，其中递送的治疗旨在治疗心脏病症，递送镇痛刺激，确定递送的治疗是否成功治疗了心脏病症，并且响应于确定改变一个或多个镇痛刺激参数。还公开了能够执行这些方法的各种其它示例性方法和/或装置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式