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81. 发明申请

US20070021743A1 Compressible/expandable hydrophilic ablation electrode 审中-公开
标题翻译：可压缩/可膨胀的亲水性消融电极
公开(公告)号：US20070021743A1
公开(公告)日：2007-01-25
申请号：US11187246
申请日：2005-07-22
申请人： Robert Rioux , Paul DiCarlo
发明人： Robert Rioux , Paul DiCarlo
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B18/1492 , A61B2018/00214 , A61B2018/00577 , A61B2018/1472 , A61B2218/002
摘要： Methods, probe assemblies and systems are provided for treating tissue a margins surrounding interstitial spaces created via the removal of tumors. The interstitial space may be in any tissue, e.g., breast tissue, and the interstitial space may be created by removing abnormal tissue. A hydrophilic electrode is compressed and introduced (e.g., percutaneously) into the interstitial cavity. An electrically conductive liquid (e.g., saline) is applied to the electrode, such that the electrode absorbs the electrically conductive liquid. The electrode is expanded into contact with the tissue margin, and electrical energy (e.g., radio frequency (RF) energy) is conveyed to the electrode, thereby ablating the tissue margin.
摘要翻译：提供了方法，探针组件和系统用于处理通过去除肿瘤产生的间质空间周围的边缘的组织。间质空间可以在任何组织，例如乳房组织中，并且间隙空间可以通过去除异常组织来产生。将亲水电极压缩并引入（例如经皮）到间质腔中。将导电液体（例如盐水）施加到电极，使得电极吸收导电液体。电极膨胀成与组织边缘接触，电能（例如，射频（RF）能量）被传送到电极，从而消融组织边缘。

82. 发明授权

US07087051B2 Articulating radio frequency probe handle 有权
标题翻译：铰接射频探头手柄
公开(公告)号：US07087051B2
公开(公告)日：2006-08-08
申请号：US10345669
申请日：2003-01-15
申请人： George Bourne , Robert Rioux
发明人： George Bourne , Robert Rioux
IPC分类号： A61B18/18
CPC分类号： A61B18/148 , A61B18/1477 , A61B2018/1425 , A61B2018/143 , A61B2090/374 , A61B2090/376
摘要： A medical probe assembly and method for ablating tissue using radio frequency energy. The medical probe assembly includes an elongated shaft, a needle electrode array, and a hinged handle. The handle has a collar, which when in the up position covers the hinge so that the device can be used as a conventional medical probe. When the collar is in the down position the hinge is exposed, and the handle can be bent to reduce its overall height. With this reduced height the probe can be used while a patient is lying in a CT scanner or an MRI chamber. Therefore, the surgeon can monitor the ablation during the procedure, and thus avoid unnecessary damage to the surrounding healthy tissue on the one hand, and insufficient ablation of the diseased tissue on the other hand. An alternate embodiment uses a flexible handle instead of a hinged one.
摘要翻译：一种用于使用射频能量消融组织的医疗探针组件和方法。医疗探针组件包括细长轴，针电极阵列和铰接手柄。手柄具有一个套环，当其向上位置覆盖铰链时，该装置可用作传统的医用探针。当衣领处于向下位置时，铰链被暴露，并且手柄可以弯曲以减小其整体高度。随着这种降低的高度，当患者躺在CT扫描仪或MRI室中时，可以使用探头。因此，外科医生可以在手术过程中监测消融，因此避免了一方面对周围健康组织的不必要的损伤，另一方面避免了患病组织的消融不足。替代实施例使用柔性手柄而不是铰接的手柄。

83. 发明申请

US20060025764A1 Systems and methods for performing simultaneous ablation 有权
公开(公告)号：US20060025764A1
公开(公告)日：2006-02-02
申请号：US11238403
申请日：2005-09-28
申请人： Robert Rioux , Robert Garabedian , Jerry Jarrard
发明人： Robert Rioux , Robert Garabedian , Jerry Jarrard
IPC分类号： A61B18/14
CPC分类号： A61B18/148 , A61B18/1206 , A61B2018/00702 , A61B2018/00875 , A61B2018/143 , A61B2018/1475
摘要： A system for treating tissue includes first and second ablation devices each including a plurality of wire electrodes and coupled to a generator in parallel. In one embodiment, the generator includes first and second terminals coupled in parallel to one another, and the first and second ablation devices are connected to the first and second terminals, respectively. Alternatively, the first and second ablation devices are coupled to a single terminal of the generator using a “Y” cable. A ground electrode is coupled to the generator opposite the first and second ablation devices for monopolar operation. The first and second arrays of electrodes are inserted into first and second sites adjacent one another within a tissue region. Energy is simultaneously delivered to the first and second arrays to generate lesions at the first and second sites preferably such that the first and second lesions overlap.

84. 发明申请

US20060015132A1 Probe introducer with valve assembly to minimize air entry 审中-公开
标题翻译：带阀门组件的探头引导器，以最大限度地减少空气进入
公开(公告)号：US20060015132A1
公开(公告)日：2006-01-19
申请号：US10892866
申请日：2004-07-16
申请人： Robert Rioux , Kristian Dimatteo
发明人： Robert Rioux , Kristian Dimatteo
IPC分类号： A61M29/00
CPC分类号： A61B17/3462 , A61B17/3498 , A61B18/148 , A61M39/0606
摘要： A medical probe introducer includes a cannula having an axial lumen, and a valve assembly connected to the cannula. The valve assembly is configured to allow passage of a medical probe (e.g., a stylet probe, a biopsy probe, or a RF ablation probe), while substantially preventing the passage of air, through the cannula lumen.
摘要翻译：医疗探针引导器包括具有轴向内腔的插管和连接到套管的阀组件。阀组件构造成允许医疗探针（例如，探针，活检探针或RF消融探针）通过，同时基本上防止空气通过套管内腔。

85. 发明申请

US20060015098A1 Apparatus and methods for assisting ablation of tissue using magnetic beads 有权
标题翻译：使用磁珠辅助组织消融的装置和方法
公开(公告)号：US20060015098A1
公开(公告)日：2006-01-19
申请号：US11224864
申请日：2005-09-12
申请人： Robert Rioux , Robert Garabedian
发明人： Robert Rioux , Robert Garabedian
IPC分类号： A61B18/14 , A61F7/00 , A61F7/12
CPC分类号： A61N1/406 , A61N2/02
摘要： A system for treating tissue includes a source of conductive and/or magnetic beads, a first member, e.g., a catheter or cannula, coupled to the source of magnetic beads, and a second member, e.g., a catheter or cannula, carrying a magnet on its distal end. The system is used for ablating or otherwise treating tissue within a target tissue region including a blood vessel contacting or passing therethrough. Magnetic beads are introduced into the target tissue region, e.g., using the first member, and a magnetic field is generated within the target tissue region, e.g., using the second member, to cause the magnetic beads to migrate towards a wall of the vessel. Energy is delivered into the target tissue region, e.g., to heat tissue therein, and the magnetic beads may attenuate or enhance treatment of tissue adjacent to the vessel.
摘要翻译：用于治疗组织的系统包括导电和/或磁珠的源，耦合到磁珠源的第一构件，例如导管或插管，以及携带磁体的第二构件，例如导管或套管在其远端。该系统用于烧蚀或以其他方式处理包括接触或穿过其中的血管的靶组织区域内的组织。将磁珠引入目标组织区域，例如使用第一构件，并且例如使用第二构件在目标组织区域内产生磁场，使磁珠朝向容器的壁迁移。能量被递送到目标组织区域中，例如以加热其中的组织，并且磁珠可以减弱或增强对与血管相邻的组织的治疗。

86. 发明申请

US20050238870A1 Embolization 审中-公开
标题翻译：栓塞
公开(公告)号：US20050238870A1
公开(公告)日：2005-10-27
申请号：US10830195
申请日：2004-04-22
申请人： Marcia Buiser , Paul DiCarlo , Thomas Casey , Erin McKenna , Robert Rioux
发明人： Marcia Buiser , Paul DiCarlo , Thomas Casey , Erin McKenna , Robert Rioux
IPC分类号： A61K47/48 , C08J9/00 , B32B5/16
CPC分类号： A61K47/557 , Y10T428/25
摘要： Embolization, as well as related compositions and methods, are disclosed.
摘要翻译：栓塞以及相关组合物和方法被公开。

87. 发明申请

US20050171525A1 System and method for performing ablation using a balloon 有权
标题翻译：使用气球进行消融的系统和方法
公开(公告)号：US20050171525A1
公开(公告)日：2005-08-04
申请号：US10768037
申请日：2004-02-02
申请人： Robert Rioux , Paul DiCarlo
发明人： Robert Rioux , Paul DiCarlo
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/14 , A61B18/1482 , A61B2018/00166 , A61B2018/00214 , A61B2018/0022 , A61B2018/00238 , A61B2018/00255 , A61B2018/00547 , A61B2018/00559 , A61B2018/00577 , A61B2018/00702 , A61B2018/00875
摘要： An apparatus comprises a catheter, a conductive element and a balloon. The catheter has a lumen. The conductive element is disposed along the catheter. The balloon has an interior in fluid communication with the lumen of the catheter. The balloon is formed of a conductive material conductively coupled to the conductive element. The balloon has a collapsed configuration and an expanded configuration.
摘要翻译：一种装置包括导管，导电元件和气球。导管有一个内腔。导电元件沿导管设置。气囊具有与导管的内腔流体连通的内部。气球由导电性地耦合到导电元件的导电材料形成。气球具有收缩配置和扩展配置。

88. 发明申请

US20050070888A1 Medical device systems and methods 有权
标题翻译：医疗器械系统和方法
公开(公告)号：US20050070888A1
公开(公告)日：2005-03-31
申请号：US10977255
申请日：2004-10-29
申请人： Kristian Dimatteo , William Shaw , Robert Rioux
发明人： Kristian Dimatteo , William Shaw , Robert Rioux
IPC分类号： A61F2/958 , A61B18/14
CPC分类号： A61B18/1492 , A61B17/22012 , A61B17/32 , A61B2018/00214 , A61B2018/0022 , A61B2018/1467 , A61B2018/1475
摘要： Medical devices and related methods are disclosed.
摘要翻译：公开了医疗器械及相关方法。

89. 发明申请

US20050020965A1 Devices and methods for delivering agents to tissue region while preventing leakage 审中-公开
标题翻译：用于将药剂递送到组织区域同时防止泄漏的装置和方法
公开(公告)号：US20050020965A1
公开(公告)日：2005-01-27
申请号：US10926853
申请日：2004-08-25
申请人： Robert Rioux , Steve Anderson , Paul DiCarlo
发明人： Robert Rioux , Steve Anderson , Paul DiCarlo
IPC分类号： A61M25/00 , A61N1/30
CPC分类号： A61M25/007 , A61B18/1477 , A61B2018/0063 , A61M25/003 , A61M25/0084 , A61M2025/0004 , A61M2025/0039 , A61M2025/0089
摘要： An apparatus for delivering a therapeutic or diagnostic agent to a target site within a body includes an outer tubular body, an inner tubular body slidably disposed within the outer tubular body, a substance delivery port located on the inner tubular body, and an electrode secured to the outer tubular body. The delivery port can be used to deliver a medical substance to the target site, and the electrode can be used to seal an access channel leading to the treatment site, thereby substantially preventing migration of material from the delivery site. In order to minimize the profile of the apparatus, a braided conductor can extend through the wall of the outer tubular body, thereby providing a means for delivering electrical energy to the electrode, while strengthening the wall of the outer tubular body to minimize the risk of rupture during delivery of the substance.
摘要翻译：用于将治疗剂或诊断剂递送到体内的靶部位的装置包括外管状体，可滑动地设置在外管状体内的内管体，位于内管体上的物质输送口，以及固定到外管体。输送口可以用于将药物输送到目标部位，并且电极可用于密封通向治疗部位的通道，从而基本上防止材料从输送部位迁移。为了最小化装置的轮廓，编织导体可以延伸穿过外部管状体的壁，从而提供用于将电能传递到电极的装置，同时加强外部管状体的壁以最小化在物质运送过程中破裂。

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