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81. 发明授权

US08346333B2 Systems and methods for estimating values of a continuous wavelet transform 有权
公开(公告)号：US08346333B2
公开(公告)日：2013-01-01
申请号：US12512132
申请日：2009-07-30
申请人： James Nicholas Watson , Paul Stanley Addison , Braddon M. Van Slyke
发明人： James Nicholas Watson , Paul Stanley Addison , Braddon M. Van Slyke
IPC分类号： A61B5/1455 , A61B5/00 , G01N33/48
CPC分类号： A61B5/726 , A61B5/0205 , A61B5/1455 , A61B5/14551 , A61B5/7203 , G06F17/148 , G06K9/00523
摘要： According to embodiments, techniques for estimating scalogram energy values in a wedge region of a scalogram are disclosed. A pulse oximetry system including a sensor or probe may be used to receive a photoplethysmograph (PPG) signal from a patient or subject. A scalogram, corresponding to the obtained PPG signal, may be determined. In an arrangement, energy values in the wedge region of the scalogram may be estimated by calculating a set of estimation locations in the wedge region and estimating scalogram energy values at each location. In an arrangement, scalogram energy values may be estimated based on an estimation scheme and by combining scalogram values in a vicinity region. In an arrangement, the vicinity region may include energy values in a resolved region of the scalogram and previously estimated energy values in the wedge region of the scalogram. In an arrangement, one or more signal parameters may be determined based on the resolved and estimated values of the scalogram.

82. 发明授权

US08255029B2 Method of analyzing and processing signals 有权
标题翻译：信号分析处理方法
公开(公告)号：US08255029B2
公开(公告)日：2012-08-28
申请号：US10547430
申请日：2004-02-27
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/00
CPC分类号： A61B5/726 , A61B5/0002 , A61B5/0082 , A61B5/02416 , A61B5/02438 , A61B5/0816 , A61B5/14551 , A61B5/14552 , A61B5/4818 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6896 , A61B5/7207 , A61B5/7214 , A61B5/7278 , A61B5/7282 , A61B5/742 , A61B2503/06 , G01N21/3151 , G06F19/00
摘要： A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system can be used as a general monitor, or more specifically, to for infant or adult apnea, and to guard against sudden infant death syndrome. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component.
摘要翻译：公开了一种生理测量系统，其可以从患者获取诸如光谱体积图的脉搏血氧测定信号，然后分析该信号以测量生理参数，包括呼吸，脉搏，氧饱和度和运动。该系统可以用作一般监视器，或者更具体地用于婴儿或成人呼吸暂停，并且防止突然的婴儿死亡综合征。该系统包括脉搏血氧计，其包括发光装置和可附接到对象的光电检测器，以获得脉搏血氧饱和度信号; 模拟数字转换器装置，被布置成将所述脉搏血氧测定信号转换成数字脉搏血氧饱和度信号; 信号处理装置，适于接收所述数字脉搏血氧饱和度信号，并被布置成通过小波变换装置分解该信号; 特征提取装置，被布置成从分解信号中导出生理信息; 分析器组件，被布置成从特征提取装置收集信息; 以及数据输出装置，被布置成与分析器组件通信。

83. 发明授权

US08235911B2 Methods and systems for filtering a signal according to a signal model and continuous wavelet transform techniques 有权
标题翻译：根据信号模型和连续小波变换技术对信号进行滤波的方法和系统
公开(公告)号：US08235911B2
公开(公告)日：2012-08-07
申请号：US12245356
申请日：2008-10-03
申请人： James Nicholas Watson , Paul Stanley Addison
发明人： James Nicholas Watson , Paul Stanley Addison
IPC分类号： A61B5/026 , G06F19/00 , G06F15/00 , G11C17/00
CPC分类号： A61B5/726 , A61B5/14551 , A61B5/7203
摘要： According to embodiments, systems and methods are provided for filtering a signal. A first reference signal may be generated according to a signal model and a second reference signal may be generated by analyzing a continuous wavelet transform of a signal. The first and second reference signals may then both be applied to an input signal to filter the input signal according to the components of both of the reference signals.
摘要翻译：根据实施例，提供了用于过滤信号的系统和方法。可以根据信号模型生成第一参考信号，并且可以通过分析信号的连续小波变换来生成第二参考信号。然后可以将第一和第二参考信号都应用于输入信号，以根据两个参考信号的分量对输入信号进行滤波。

84. 发明授权

US08082110B2 Low perfusion signal processing systems and methods 有权
标题翻译：低灌注信号处理系统和方法
公开(公告)号：US08082110B2
公开(公告)日：2011-12-20
申请号：US12249325
申请日：2008-10-10
申请人： James Nicholas Watson , Paul Stanley Addison , Edward M. McKenna
发明人： James Nicholas Watson , Paul Stanley Addison , Edward M. McKenna
IPC分类号： G01N33/48
CPC分类号： G06F19/10 , A61B5/0261 , A61B5/1455 , A61B5/726 , G01N33/48
摘要： In some embodiments, systems and methods for identifying a low perfusion condition are provided by transforming a signal using a wavelet transform to generate a scalogram. A pulse band and adjacent marker regions in the scalogram are identified. Characteristics of the marker regions are used to detect the existence of a lower perfusion condition. If such a condition is detected, an event may be triggered, such as an alert or notification.
摘要翻译：在一些实施例中，用于识别低灌注条件的系统和方法通过使用小波变换变换信号以产生缩放图来提供。识别出标尺中的脉冲带和相邻的标记区域。标记区域的特征用于检测较低灌注条件的存在。如果检测到这种情况，则可能触发事件，例如警报或通知。

85. 发明申请

US20110004069A1 Systems And Methods For Processing Physiological Signals In Wavelet Space 有权
标题翻译：小波空间处理生理信号的系统与方法
公开(公告)号：US20110004069A1
公开(公告)日：2011-01-06
申请号：US12497822
申请日：2009-07-06
申请人： James P. Ochs , Paul Stanley Addison , James Nicholas Watson
发明人： James P. Ochs , Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/00
CPC分类号： A61B5/7235 , A61B5/024 , A61B5/02416 , A61B5/14542 , A61B5/14551 , A61B5/7203 , A61B5/7207 , A61B5/7225 , A61B5/726 , A61B5/7264 , G06F19/00
摘要： Methods and systems are disclosed for analyzing multiple scale bands in the scalogram of a physiological signal in order to obtain information about a physiological process. An analysis may be performed to identify multiple scale bands that are likely to contain the information sought. Each scale band may be assessed to determine a band quality, and multiple bands may be combined based on the band quality. Information about a physiological process may determined based on the combined band. In an embodiment, analyzing multiple scale bands in a scalogram arising from a wavelet transformation of a photoplethysmograph signal may yield clinically relevant information about, among other things, the blood oxygen saturation of a patient.
摘要翻译：公开了用于分析生理信号的标尺中的多个尺度带以获得关于生理过程的信息的方法和系统。可以执行分析以识别可能包含所寻求信息的多个尺度带。可以评估每个标度带以确定带质量，并且可以基于带质量来组合多个频带。关于生理过程的信息可以基于组合的带来确定。在一个实施例中，分析由光体积描记信号的小波变换产生的标尺中的多个尺度带可产生关于患者的血氧饱和度的临床相关信息。

86. 发明申请

US20100324431A1 Determining Disease State Using An Induced Load 审中-公开
标题翻译：使用感应负荷确定疾病状态
公开(公告)号：US20100324431A1
公开(公告)日：2010-12-23
申请号：US12487470
申请日：2009-06-18
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/02
CPC分类号： A61B5/02007 , A61B5/02416 , A61B5/14551 , A61B5/4884 , A61B5/726
摘要： The present disclosure relates to determining a patient's disease state based at least in pail on obtaining or determining certain underlying characteristics, such as vasotone, venous compliance, or ability of the vascular system to drain venous blood, of the patient's vascular system. The characteristics may be obtained by analyzing changes to a patient signal, such as the overall signal change, the rate of change, the shape of the change, changes in signal energy, or changes in the baseline and/or the amplitude of the signal, and/or the time period(s) over which the signal changes, that are caused by inducing a load on the vascular system. In some embodiments, the signal changes may be analyzed by transforming the signal using, for example, a continuous wavelet transform. The patient's health status or disease state may be determined using the one or more vascular system characteristics that influenced the signal change.
摘要翻译：本公开涉及至少在桶中获得或确定患者血管系统的某些潜在特征（例如血管舒张，静脉顺应性或血管系统排出静脉血的能力）来确定患者的疾病状态。可以通过分析患者信号的变化（例如整体信号变化，变化率，变化的形状，信号能量的变化，或基线的变化和/或信号的幅度）来获得特征，和/或通过在血管系统上引起负载而引起的信号变化的时间段。在一些实施例中，可以使用例如连续小波变换来变换信号来分析信号变化。可以使用影响信号变化的一种或多种血管系统特征来确定患者的健康状况或疾病状态。

87. 发明申请

US20100081898A1 Detecting A Probe-Off Event In A Measurement System 有权
标题翻译：在测量系统中检测探测事件
公开(公告)号：US20100081898A1
公开(公告)日：2010-04-01
申请号：US12242894
申请日：2008-09-30
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/1455
CPC分类号： G06K9/527 , A61B5/14551 , A61B5/6843 , A61B5/726
摘要： According to embodiments, techniques for detecting probe-off events are disclosed. A sensor or probe may be used to obtain a plethysmograph or photoplethysmograph (PPG) signal from a subject. A wavelet transform of the signal may be performed and a scalogram may be generated based at least in part on the wavelet transform. One or more characteristics of the scalogram may be determined. The determined characteristics may include, for example, an energy decrease, a broadscale high-energy cone, a regular, repeated high-scale pattern, a low-scale information pattern; and a pulse band. The absence or presence of these and other characteristics, along with information about the characteristics, may be analyzed to detect a probe-off event. A confidence indicator may be calculated in connection with probe-off event detections and alarms may be generated when probe-off events occur.
摘要翻译：根据实施例，公开了用于检测探测事件的技术。可以使用传感器或探针来获得来自受试者的体积描记器或光电体积描记器（PPG）信号。可以执行信号的小波变换，并且可以至少部分地基于小波变换来生成缩放图。可以确定缩放图的一个或多个特征。确定的特性可以包括例如能量减少，大尺度高能量锥，规则的，重复的高比例图案，低比例的信息图案; 和脉冲带。可以分析这些和其他特征的缺失或存在以及关于特征的信息以检测探测事件。可以结合探测事件检测计算置信指标，并且可以在发生探测事件时生成报警。

88. 发明申请

US20100014724A1 SIGNAL PROCESSING SYSTEMS AND METHODS USING BASIS FUNCTIONS AND WAVELET TRANSFORMS 有权
标题翻译：信号处理系统和使用基函数和小波变换的方法
公开(公告)号：US20100014724A1
公开(公告)日：2010-01-21
申请号：US12245435
申请日：2008-10-03
申请人： James Nicholas Watson , Paul Stanley Addison
发明人： James Nicholas Watson , Paul Stanley Addison
IPC分类号： G06K9/00
CPC分类号： A61B5/00 , A61B5/14551 , A61B5/7203 , A61B5/726 , G06F19/00 , G06K9/00516
摘要： According to embodiments, systems and methods are provided that use continuous wavelet transforms and basis functions to provide an optimized system for the determination of physiological information. In an embodiment, the basis functions may be used to refine an area of interest in the signal in frequency or in time, and the continuous wavelet transform may be used to identify a maxima ridge in the scalogram at scales with characteristic frequencies proximal to the frequency or frequencies of interest. In another embodiment, a wavelet transform may be used to identify regions of a signal with the morphology of interest while basis functions may be used to focus on these regions to determine or filter information of interest. In yet another embodiment, basis functions and continuous wavelet transforms may be used concurrently and their results combined to form optimized information or a confidence metric for determined physiological information.
摘要翻译：根据实施例，提供了使用连续小波变换和基函数来提供用于确定生理信息的优化系统的系统和方法。在一个实施例中，基函数可以用于在频率或时间上细化信号中的感兴趣区域，并且连续小波变换可以用于在具有接近频率的特征频率的标度上识别标尺中的最大值脊或兴趣频率。在另一个实施例中，可以使用小波变换来识别具有感兴趣形态的信号的区域，而基函数可用于集中在这些区域上以确定或滤除感兴趣的信息。在又一个实施例中，可以同时使用基函数和连续小波变换，并将其结果组合以形成用于确定的生理信息的优化信息或置信度量。

89. 发明申请

US20090324033A1 Signal Processing Systems and Methods for Determining Slope Using an Origin Point 审中-公开
标题翻译：使用原点确定坡度的信号处理系统和方法
公开(公告)号：US20090324033A1
公开(公告)日：2009-12-31
申请号：US12242881
申请日：2008-09-30
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： G06K9/00
CPC分类号： A61B5/14551 , A61B5/7203 , A61B5/7225 , A61B5/726
摘要： The present disclosure relates to signal processing and, more particularly, relates to determining the slope of a signal. In embodiments, slopes between an origin point of the plot and at least two points in the signal may be determined. The slopes may be used to generate a histogram, and a desired slope of the signal corresponding to a preferred value in the histogram may be selected. In an embodiment, a two-dimensional Lissajous figure may be selected from a three-dimensional Lissajous figure and a histogram of the slopes within the selected Lissajous figure may be created to determine the desired slope. The desired slope may have clinical relevance (e.g., it may be used to determine a patient's blood oxygen saturation level). The three-dimensional Lissajous figure may be derived from surface signals related to two scalograms. Each scalogram may be the result of performing a continuous wavelet transform on a signal. A confidence measure may be generated with respect to determining the desired slope.
摘要翻译：本公开涉及信号处理，更具体地涉及确定信号的斜率。在实施例中，可以确定绘图的原点与信号中的至少两个点之间的斜率。可以使用斜率来生成直方图，并且可以选择与直方图中的优选值对应的信号的期望斜率。在一个实施例中，可以从三维李萨如图中选择二维李萨如图，并且可以创建所选择的李萨如图中的斜率的直方图以确定期望的斜率。期望的斜率可能具有临床相关性（例如，其可以用于确定患者的血氧饱和度水平）。三维李萨如图可能来自与两个标尺相关的表面信号。每个标尺可能是对信号执行连续小波变换的结果。可以产生相对于确定期望斜率的置信度量度。

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