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81. 发明申请

US20120015435A1 PCSK9 ANTAGONISTS 有权
公开(公告)号：US20120015435A1
公开(公告)日：2012-01-19
申请号：US13225119
申请日：2011-09-02
申请人： Hong Liang , Yasmina Noubia Abdiche , Javier Fernando Chaparro Riggers , Bruce Charles Gomes , Julie Jia Li Hawkins , Jaume Pons , Yuli Wang
发明人： Hong Liang , Yasmina Noubia Abdiche , Javier Fernando Chaparro Riggers , Bruce Charles Gomes , Julie Jia Li Hawkins , Jaume Pons , Yuli Wang
IPC分类号： C12N5/10 , C12N1/21 , C12N1/19 , C07H21/00
CPC分类号： C07K16/40 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K2299/00 , C07K2317/24 , C07K2317/33 , C07K2317/76 , C07K2317/92
摘要： The present invention provides antagonizing antibodies, antigen-binding portions thereof, and aptamers that bind to proprotein convertase subtilisin kexin type 9 (PCSK9). Also provided are antibodies directed to peptides, in which the antibodies bind to PCSK9. The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acid. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease, including treatment of hypercholesterolemia.
摘要翻译：本发明提供了与抗蛋白转化酶枯草杆菌蛋白酶Kexin 9型（PCSK9）结合的拮抗抗体，其抗原结合部分和适体。还提供了针对肽的抗体，其中抗体结合PCSK9。本发明还提供了获得这样的抗体和抗体编码核酸的方法。本发明还涉及使用这些抗体及其抗原结合部分来降低LDL-胆固醇水平和/或用于治疗和/或预防心血管疾病（包括治疗高胆固醇血症）的治疗方法。

82. 发明授权

US08004247B1 Switchable battery charger circuit 有权
标题翻译：可切换电池充电器电路
公开(公告)号：US08004247B1
公开(公告)日：2011-08-23
申请号：US12110028
申请日：2008-04-25
申请人： Hong Liang Zhang
发明人： Hong Liang Zhang
IPC分类号： H02J7/00 , H02J1/10
CPC分类号： H02J7/0055 , Y10T307/50 , Y10T307/696
摘要： In one or more embodiments, a battery charger switching circuit enables a device to automatically select between multiple device interfaces individual ones of which are connectable to different power supplies for recharging the device. In at least some embodiments, selection of a particular device interface is based upon the magnitude of the voltage associated with a particular power supply. For example, the battery charger switching circuit can ascertain charge voltages associated with individual power supplies and select a power supply having a greater magnitude of charge voltage. In at least some embodiments, the battery charger switching circuit can enable charge control circuits associated with a particular power supply and disable charge control circuits associated with unselected power supplies in a manner that reduces or eliminates leakage current associated with unselected power supplies.
摘要翻译：在一个或多个实施例中，电池充电器切换电路使得设备能够在多个设备接口之间自动选择，其中各个设备接口可连接到不同的电源以对设备再充电。在至少一些实施例中，特定设备接口的选择基于与特定电源相关联的电压的大小。例如，电池充电器开关电路可以确定与各个电源相关联的充电电压，并选择具有更大幅度的充电电压的电源。在至少一些实施例中，电池充电器开关电路可以使得与特定电源相关联的充电控制电路能够以与减少或消除与未选择的电源相关联的泄漏电流的方式禁用与未选择的电源相关联的充电控制电路。

83. 发明申请

US20110119261A1 SEARCHING USING SEMANTIC KEYS 审中-公开
标题翻译：搜索使用语义键
公开(公告)号：US20110119261A1
公开(公告)日：2011-05-19
申请号：US13012690
申请日：2011-01-24
申请人： Hong Liang Qiao
发明人： Hong Liang Qiao
IPC分类号： G06F17/30
CPC分类号： G06F16/9535 , G06F16/3338 , G06F16/36 , G06F16/951
摘要： A method, computer-readable medium, and a computer system for performing a search are disclosed. Embodiments of the present invention provide a convenient and efficient mechanism for performing a search based on search data, where the search data may include a search query and at least one semantic key. The semantic key may be used to determine at least one document. Results from the search may be filtered using the at least one document. In this manner, more relevant search results may be returned.
摘要翻译：公开了一种用于执行搜索的方法，计算机可读介质和计算机系统。本发明的实施例提供了一种用于基于搜索数据执行搜索的便利和有效的机制，其中搜索数据可以包括搜索查询和至少一个语义密钥。语义密钥可以用于确定至少一个文档。可以使用至少一个文档来过滤搜索结果。以这种方式，可以返回更相关的搜索结果。

84. 发明申请

US20110020609A1 PANEL AND METHOD OF MAKING THE SAME 审中-公开
标题翻译：面板及其制造方法
公开(公告)号：US20110020609A1
公开(公告)日：2011-01-27
申请号：US12840596
申请日：2010-07-21
申请人： Steven Lynch , Geoffrey Hardwick , Timothy Gouge , Robert Allen , Bei-Hong Liang , Michael Macdonald , Peter Moran , Michael Halton , Jonathan Pugsley , Michael Conlon
发明人： Steven Lynch , Geoffrey Hardwick , Timothy Gouge , Robert Allen , Bei-Hong Liang , Michael Macdonald , Peter Moran , Michael Halton , Jonathan Pugsley , Michael Conlon
IPC分类号： B32B3/30 , B27N3/08 , B28B11/08 , B32B9/06 , B32B7/02
CPC分类号： E04C2/16 , B27N5/00 , E04C2/328 , E06B3/7001 , Y10T428/24612 , Y10T428/24992
摘要： A panel and method of making a panel is disclosed. One described panel comprises a core comprising a flat region and a contoured region, wherein the contoured region comprises a convex feature, a first adjacent base and a second adjacent base, the apex of the convex feature has a first caliper, the first adjacent base has a second caliper smaller than the first caliper, and the second adjacent base has a third caliper smaller than the first caliper.
摘要翻译：公开了一种面板和制造面板的方法。一个描述的面板包括一个包括一个平坦区域和一个轮廓区域的芯子，其中该轮廓区域包括凸形特征，一个第一相邻基部和一个第二相邻基部，该凸形特征的顶点具有第一卡尺，第二卡尺小于第一卡钳，并且第二相邻基座具有小于第一卡钳的第三卡钳。

85. 发明申请

US20100229476A1 REVERSE MOLDED PANEL 有权
标题翻译：反向模制面板
公开(公告)号：US20100229476A1
公开(公告)日：2010-09-16
申请号：US12786887
申请日：2010-05-25
申请人： Steven K. LYNCH , Dale E. Schafernak , Karine Luetgert , Bei-Hong Liang , Lee Braddock
发明人： Steven K. LYNCH , Dale E. Schafernak , Karine Luetgert , Bei-Hong Liang , Lee Braddock
IPC分类号： E04C2/52 , B29C43/02 , B32B5/16 , E04C2/26
CPC分类号： E04F13/10 , B27N3/08 , B29K2311/14 , B44C3/046 , B44C5/043 , B44C5/0453 , B44C5/0461 , E04F13/18 , Y10T428/24066 , Y10T428/24091 , Y10T428/24479 , Y10T428/24521 , Y10T428/24529 , Y10T428/24554 , Y10T428/24595 , Y10T428/24603 , Y10T428/24736 , Y10T428/2495 , Y10T428/253 , Y10T428/31989
摘要： A reverse molded fiberboard panel; a wainscot kit comprising a plurality of differently sized reverse molded panels, and a planar finishing or spacer panel, adapted to completely cover any size wall between a wall base board and a wall chair rail; and a method of reverse molding a loose cellulosic mat, in a single pressing step, to provide one or more relatively high density, raised panels without requiring preliminary pressing, or other pre-shaping step, such as scalping. The reverse-molded panels are molded in a conventional, multi-opening fiberboard press, in a single pressing step process, while achieving excellent transfer of mold detail (embossing fidelity) without visually noticeable fiber fracture.
摘要翻译：反模压纤维板; 包括多个不同尺寸的逆模制板的壁板组件，以及适于完全覆盖壁基板和壁椅导轨之间的任何尺寸壁的平面整理或间隔板; 以及在单个压制步骤中反向模制松散的纤维素垫的方法，以提供一个或多个相对高密度的凸起面板，而不需要预先压制或其它预成型步骤，例如烫伤。反转模制板在一个单一的压制步骤中以常规的多开口纤维板压机成型，同时实现模具细节（压花保真度）的极好的转移，而没有明显的纤维断裂。

86. 发明申请

US20100222030A1 SYSTEM AND METHOD FOR SENDING AN AUDIO MESSAGE BY MOBILE PHONE DURING COMMUNICATION 审中-公开
标题翻译：用于在通信期间通过移动电话发送音频消息的系统和方法
公开(公告)号：US20100222030A1
公开(公告)日：2010-09-02
申请号：US12482047
申请日：2009-06-10
申请人： HONG-LIANG LIU , AI-TING ZHANG
发明人： HONG-LIANG LIU , AI-TING ZHANG
IPC分类号： H04M11/10
CPC分类号： H04M1/642 , H04M1/72519 , H04M1/7255
摘要： A system and method is used for transmitting an audio message by mobile phones during communication with a remote terminal. The system includes a detecting module, a storage module, a voice processing module, and an output control module. The detecting module detects whether the mobile phone is communicating with the remote terminal, and transmits a busy signal to the storage module when the mobile phone is communicating with the remote terminal. The storage module stores a plurality of digital voice signals, and transmits the corresponding digital voice signal to the voice processing module when receives the busy signal. The voice processing module converts the corresponding digital voice signal to audible voice message, and transmits the audible voice message to an output control module. The output control module transmits the audible voice message from the voice processing module to the remote terminal together with communicating voice message.
摘要翻译：系统和方法用于在与远程终端通信期间通过移动电话发送音频消息。该系统包括检测模块，存储模块，语音处理模块和输出控制模块。检测模块检测移动电话是否与远程终端通信，并且当移动电话正在与远程终端进行通信时，将忙信号发送到存储模块。存储模块存储多个数字语音信号，并且当接收到忙信号时，将对应的数字语音信号发送到语音处理模块。语音处理模块将相应的数字语音信号转换成声音语音消息，并将可听话音消息发送到输出控制模块。输出控制模块将语音处理模块的声音语音消息与通信语音消息一起发送到远程终端。

87. 发明授权

US07721499B2 Reverse molded panel 有权
公开(公告)号：US07721499B2
公开(公告)日：2010-05-25
申请号：US10285430
申请日：2002-11-01
申请人： Steven K. Lynch , Dale E. Schafernak , Karine Luetgert , Bei-Hong Liang , Lee Braddock
发明人： Steven K. Lynch , Dale E. Schafernak , Karine Luetgert , Bei-Hong Liang , Lee Braddock
IPC分类号： E06B3/08 , E06B3/72 , E06B5/00 , E06B3/10
CPC分类号： E04F13/10 , B27N3/08 , B29K2311/14 , B44C3/046 , B44C5/043 , B44C5/0453 , B44C5/0461 , E04F13/18 , Y10T428/24066 , Y10T428/24091 , Y10T428/24479 , Y10T428/24521 , Y10T428/24529 , Y10T428/24554 , Y10T428/24595 , Y10T428/24603 , Y10T428/24736 , Y10T428/2495 , Y10T428/253 , Y10T428/31989
摘要： A reverse molded fiberboard panel; a wainscot kit comprising a plurality of differently sized reverse molded panels, and a planar finishing or spacer panel, adapted to completely cover any size wall between a wall base board and a wall chair rail; and a method of reverse molding a loose cellulosic mat, in a single pressing step, to provide one or more relatively high density, raised panels without requiring preliminary pressing, or other pre-shaping step, such as scalping. The reverse-molded panels are molded in a conventional, multi-opening fiberboard press, in a single pressing step process, while achieving excellent transfer of mold detail (embossing fidelity) without visually noticeable fiber fracture.

88. 发明授权

US07699655B2 Electrical connector having a shielding shell 失效
标题翻译：具有屏蔽壳的电连接器
公开(公告)号：US07699655B2
公开(公告)日：2010-04-20
申请号：US12317825
申请日：2008-12-29
申请人： Hong-Liang Wang , Ming Zhang
发明人： Hong-Liang Wang , Ming Zhang
IPC分类号： H01R13/648
CPC分类号： H01R12/57 , H01R12/714 , H01R13/6582
摘要： An electrical connector includes an insulative housing (2), a plurality of terminals (3) received in the insulative housing (2) and a shielding shell (4) covering the insulative housing. The insulative housing (2) includes a mating opening (24) extending along a longitudinal direction and a pair of grooves (231) extending with an angle to the mating opening and opening to an exterior. The shielding shell is provided with two shielding shell (41), (42) attached to an outer periphery of the insulative housing (2), which their ends are received and retained in the grooves (231).
摘要翻译：电连接器包括绝缘壳体（2），容纳在绝缘壳体（2）中的多个端子（3）和覆盖绝缘壳体的屏蔽壳体（4）。绝缘壳体（2）包括沿着纵向方向延伸的配合开口（24）和一对与配合开口成角度延伸并向外部开口的凹槽（231）。屏蔽壳体设置有两个安装在绝缘壳体（2）的外周上的屏蔽壳（41），它们的端部被容纳并保持在凹槽（231）中。

89. 发明申请

US20090322542A1 SYSTEM AND METHOD FOR MONITORING AMBIENT TEMPERATURE AND HUMIDITY 审中-公开
标题翻译：用于监测环境温度和湿度的系统和方法
公开(公告)号：US20090322542A1
公开(公告)日：2009-12-31
申请号：US12436717
申请日：2009-05-06
申请人： HONG-LIANG DING , LI-XIA PENG , XIAO-HUI CHANG , YONG-GANG ZHANG , KUANG-YUAN CHANG
发明人： HONG-LIANG DING , LI-XIA PENG , XIAO-HUI CHANG , YONG-GANG ZHANG , KUANG-YUAN CHANG
IPC分类号： G08B17/00
CPC分类号： F24F11/30 , F24F11/52 , F24F2110/10 , F24F2110/20
摘要： A system and method for ambient monitoring temperature and humidity, includes a controller, a host and an alarm device. The controller includes a sensing module and a determining module. The sensing module senses temperature and humidity. The determining module determines whether the sensed environment temperature and humidity are abnormal according to predetermined standards, and determines howl long the environment continues to be abnormal, and outputs an abnormal signal if the abnormal environment continues to be abnormal beyond a preset time limit. The host is connected to the controller, to transmit an alarm signal according to the abnormal signal. The alarm device is connected to the host, to activate according to the alarm signal.
摘要翻译：一种用于环境温度和湿度监测的系统和方法，包括控制器，主机和报警装置。控制器包括感测模块和确定模块。感应模块感测温度和湿度。确定模块根据预定标准确定感测到的环境温度和湿度是否异常，并且确定环境持续异常的时间长度，并且如果异常环境在超出预设时间限制的情况下继续异常，则输出异常信号。主机连接到控制器，根据异常信号发送报警信号。报警装置连接到主机，根据报警信号进行激活。

90. 发明授权

US07539912B2 Method and apparatus for testing a fully buffered memory module 失效
标题翻译：用于测试完全缓冲存储器模块的方法和装置
公开(公告)号：US07539912B2
公开(公告)日：2009-05-26
申请号：US11611390
申请日：2006-12-15
申请人： Hong Liang Chan , Allen Lawrence , Sunny Chang , Joseph C. Klein , Bosco Lai
发明人： Hong Liang Chan , Allen Lawrence , Sunny Chang , Joseph C. Klein , Bosco Lai
IPC分类号： G11C29/00
CPC分类号： G11C29/56 , G11C5/04 , G11C11/401 , G11C29/1201 , G11C29/32 , G11C2029/5602
摘要： Described embodiments relate to a method of testing fully buffered memory modules that involves placing a buffer device, a test vectors generator, and a switch into a memory device tester, coupling the buffer device and the test vectors generator to the switch inside the tester, coupling the switch to an identical buffer device that is located on a memory module with plurality of DRAM devices, and testing the plurality of DRAM devices and the buffer device of the memory module. An apparatus implementing the method comprises a memory device tester, a memory bus, and a plurality of memory modules under test, the tester and the plurality of memory modules connected to the memory bus in a point-to-point manner, the tester comprising a buffer device, a test vectors generator, and a switch, the tester connected to the memory bus through the switch, each memory module under test having a plurality of DRAM devices and an identical buffer device.
摘要翻译：描述的实施例涉及一种测试完全缓冲的存储器模块的方法，该方法包括将缓冲器件，测试向量发生器和开关放置到存储器件测试器中，将缓冲器件和测试矢量发生器耦合到测试器内的开关，耦合切换到位于具有多个DRAM设备的存储器模块上的相同缓冲器件，并测试存储器模块的多个DRAM器件和缓冲器件。实现该方法的装置包括存储器件测试器，存储器总线和被测试的多个存储器模块，测试器和多个存储器模块以点到点的方式连接到存储器总线，测试器包括一个缓冲设备，测试向量生成器和开关，测试器通过开关连接到存储器总线，每个被测试的存储器模块具有多个DRAM器件和相同的缓冲器器件。

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