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71. 发明授权

US08119777B2 Ink jet dye design 有权
标题翻译：喷墨染色设计
公开(公告)号：US08119777B2
公开(公告)日：2012-02-21
申请号：US12237340
申请日：2008-09-24
申请人： Larrie A Deardurff
发明人： Larrie A Deardurff
IPC分类号： C07D231/46 , C07D487/04
CPC分类号： C09D11/32 , C09B29/30 , C09B55/009 , C09B69/00 , C09D11/328 , C09D11/40
摘要： Magenta chromophore dyes which are stabilized by adding steric hindering groups to protect the imino carbons; nonlimiting examples of the steric hindering groups being phenyl, methyl, ethyl, isopropyl, fluoride, chloride, bromide and iodide groups.
摘要翻译：通过加入空间阻碍基团保护亚氨基碳而稳定的洋红色发色团染料; 空间位阻基团的非限制性实例是苯基，甲基，乙基，异丙基，氟化物，氯化物，溴化物和碘化物基团。

72. 发明申请

US20080214640A1 Thrombopoietin mimetics 有权
公开(公告)号：US20080214640A1
公开(公告)日：2008-09-04
申请号：US11650651
申请日：2007-01-08
申请人： Kevin J. Duffy , Connie Erickson-Miller , Daniel F. Eppley , Julian Jenkins , Juan I. Luengo , Nannan Liu , Alan T. Price , Antony N. Shaw , Sophie Visonneau , Kenneth Wiggall
发明人： Kevin J. Duffy , Connie Erickson-Miller , Daniel F. Eppley , Julian Jenkins , Juan I. Luengo , Nannan Liu , Alan T. Price , Antony N. Shaw , Sophie Visonneau , Kenneth Wiggall
IPC分类号： A61K31/4152 , C07D231/46 , A61P7/02
CPC分类号： C07D403/12 , C07D231/48 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D417/04 , C07D417/12
摘要： Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.

73. 发明申请

US20050244349A1 Methods for stabilizing ingredients within cosmetics, personal care and household products 有权
标题翻译：在化妆品，个人护理和家庭用品中稳定成分的方法
公开(公告)号：US20050244349A1
公开(公告)日：2005-11-03
申请号：US11115395
申请日：2005-04-27
申请人： Ratan Chaudhuri , Germain Puccetti , Francois Marchio , Zoia Lascu
发明人： Ratan Chaudhuri , Germain Puccetti , Francois Marchio , Zoia Lascu
IPC分类号： C07D215/14 , A61K8/30 , A61K8/33 , A61K8/35 , A61K8/37 , A61K8/40 , A61K8/42 , A61K8/46 , A61K8/49 , A61Q1/00 , A61Q1/04 , A61Q1/06 , A61Q1/12 , A61Q3/02 , A61Q5/02 , A61Q5/06 , A61Q5/10 , A61Q5/12 , A61Q11/00 , A61Q15/00 , A61Q17/02 , A61Q17/04 , A61Q19/00 , A61Q19/04 , A61Q19/10 , C07D231/46 , C07D311/72 , C08B37/00 , C09K15/24 , C11B5/00 , C11B9/00 , C11D7/22 , C11D7/26 , C11D7/32 , C11D11/00 , A61K7/42 , A61K7/021
CPC分类号： A61K8/37 , A61K8/42 , A61K2800/52 , A61Q1/04 , A61Q1/06 , A61Q3/02 , A61Q5/02 , A61Q5/06 , A61Q5/065 , A61Q5/12 , A61Q11/00 , A61Q15/00 , A61Q17/02 , A61Q17/04 , A61Q19/00 , A61Q19/04 , A61Q19/10 , C11D3/0084 , C11D3/2093 , C11D3/26 , C11D3/32 , C11D3/40 , C11D3/50 , C11D7/266 , C11D7/3254 , C11D7/3263
摘要： The present invention relates to methods and compositions for using photostabilizer compounds for stabilizing formulation ingredients, like flavors, fragrances, colors, antioxidants, polymers, within cosmetics, personal care and household products, against degradation from sun light, heat and air oxidation resulting in improvement in storage stability, viscosity, and maintenance of color of the formulated products.
摘要翻译：本发明涉及使用光稳定剂化合物来稳定制剂成分（如香料，香料，颜色，抗氧化剂，聚合物，化妆品，个人护理和家用产品）中的防晒剂，防止太阳光降解，导致改善的热和空气氧化的方法和组合物在储存稳定性，粘度和维护配方产品的颜色。

74. 发明申请

US20050166335A1 Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative 有权
标题翻译：用于染色包含至少一种二氨基-N，N-二氢吡喃酮衍生物的角质纤维的组合物
公开(公告)号：US20050166335A1
公开(公告)日：2005-08-04
申请号：US10999999
申请日：2004-12-01
申请人： Laurent Vidal , Aziz Fadli
发明人： Laurent Vidal , Aziz Fadli
IPC分类号： C07D231/16 , A61K8/00 , A61K8/20 , A61K8/22 , A61K8/33 , A61K8/40 , A61K8/41 , A61K8/49 , A61K8/66 , A61Q5/10 , C07D231/38 , C07D231/46 , C07D231/54 , C07D487/04 , C09B57/00 , D06P1/32 , D06P3/04 , A61K7/13
CPC分类号： C07D487/04 , A61K8/494 , A61Q5/10
摘要： Disclosed herein are a composition for dyeing keratinous fibers, for example, human keratinous fibers such as hair, comprising at least one oxidation base chosen from diamino-N,N-dihydropyrazolone derivative and a method using the composition. Further disclosed herein are amino-N,N-dihydropyrazolone derivatives and the addition salts thereof and diamino-N,N-dihydropyrazolone derivatives and the addition salts thereof, as well as the methods for preparing these compounds.
摘要翻译：本文公开了用于染色角质纤维的组合物，例如人角质纤维如毛发，其包含至少一种选自二氨基-N，N-二氢吡喃酮衍生物的氧化碱和使用该组合物的方法。本文进一步公开的是氨基-N，N-二氢吡喃酮衍生物及其加成盐和二氨基-N，N-二氢吡喃酮衍生物及其加成盐以及这些化合物的制备方法。

75. 发明授权

US4784668A Novel heterocycle-containing trisazo dyes 失效
标题翻译：含新杂环的三偶氮染料
公开(公告)号：US4784668A
公开(公告)日：1988-11-15
申请号：US49225
申请日：1987-05-13
申请人： Walter Breitschaft , Udo Mayer , Guenther Seybold
发明人： Walter Breitschaft , Udo Mayer , Guenther Seybold
IPC分类号： C09B31/28 , C07D209/40 , C07D209/88 , C07D213/84 , C07D213/85 , C07D215/38 , C07D231/46 , C07D233/88 , C07D239/62 , C07D277/20 , C07D277/50 , C07D333/38 , C09B35/46 , C09D11/328 , D06P3/32 , D06P5/00 , C09D11/00
CPC分类号： C09D11/328 , C09B35/467 , D06P3/3226
摘要： Compounds which, in the form of the free acid, are of the general formula I ##STR1## where D is phenyl which unsubstituted or substituted by fluorine, chlorine, bromine, nitro, cyano, C.sub.1 -C.sub.4 -alkylsulfonyl, C.sub.1 -C.sub.8 -alkyl, C.sub.1 -C.sub.4 -alkoxy, carboxyl, C.sub.1 -C.sub.4 -alkoxycarbonyl or hydroxysulfonyl or by unsubstituted or substituted carbamyl or sulfamyl, andK is a radical of a heterocyclic coupling component, and the rings A and E may furthermore be substituted by methyl, methoxy, chlorine or hydroxysulfonyl.
摘要翻译：游离酸形式的化合物为通式Ⅰ的化合物，其中D为未被取代或被氟，氯，溴，硝基，氰基，C 1 -C 4 - 烷基磺酰基，C 1 -C 8 - 烷基，C 1 -C 4 - 烷氧基，羧基，C 1 -C 4 - 烷氧基羰基或羟基磺酰基，或未取代或取代的氨基甲酰基或亚磺酰基，K是杂环偶合组分的基团，并且环A和E可进一步被甲基，甲氧基，氯或羟基磺酰基。

76. 发明授权

US4711963A 4-amino-2-methyl-3-phenyl-1-(2,4,6-trichlorophenyl)-3-pyrazolin-5-one 失效
标题翻译： 4-氨基-2-甲基-3-苯基-1-（2,4,6-三氯苯基）-3-吡唑啉-5-酮
公开(公告)号：US4711963A
公开(公告)日：1987-12-08
申请号：US858830
申请日：1986-04-29
申请人： Yoshio Inagaki , Tadao Shishido
发明人： Yoshio Inagaki , Tadao Shishido
IPC分类号： C07D231/20 , C07D231/22 , C07D231/26 , C07D231/46 , C12Q1/28 , G01N33/52
CPC分类号： C07D231/46 , C07D231/26
摘要： Compounds are disclosed which are 4-amino-2,3-di-substituted-1-(mono- or trichlorophenyl)-3-pyrazolin-5-ones represented by the following formulae (1) to (3): ##STR1## and acid addition salts thereof. The compounds can be easily produced and are useful for qualitative analysis or quantitative analysis of hydrogen peroxide when used as a component of a color indicator composition for detecting hydrogen peroxide.
摘要翻译：公开了由下式（1）至（3）表示的4-氨基-2,3-二取代-1-（单或三氯苯基）-3-吡唑啉-5-酮的化合物：（（3）及其酸加成盐。当用作检测过氧化氢的颜色指示剂组合物的组分时，化合物可以容易地产生并且可用于定性分析或定量分析过氧化氢。

77. 发明授权

US4567139A Chromogen for measuring the formation of hydrogen peroxide based on 1-substituted-aminoantipyrin compounds 失效
标题翻译：用于测量基于1-取代 - 氨基脒基化合物的过氧化氢形成的色原体
公开(公告)号：US4567139A
公开(公告)日：1986-01-28
申请号：US469492
申请日：1983-02-24
申请人： Hans-George Batz
发明人： Hans-George Batz
IPC分类号： G01N33/48 , C07D231/26 , C07D231/46 , C12Q1/28
CPC分类号： C07D231/26 , C07D231/46 , C12Q1/28 , C12Q2326/00 , C12Q2326/50 , C12Q2326/96 , Y10S436/904 , Y10T436/206664
摘要： Compounds of the general formula ##STR1## wherein R represents an alkyl group of 1 to 3 carbon atoms or the group N(R.sub.2).sub.2, in which R.sub.2 represents a hydrogen atom, an alkyl group of 1 to 3 carbon atoms, or an acyl group of 1 to 3 carbon atoms, and R.sub.1 has the same meaning as R or is a hydrogen atom, are new and are suitable as chromogens for measuring H.sub.2 O.sub.2 formation in enzymatic reactions.
摘要翻译：其中R表示1至3个碳原子的烷基或基团N（R 2）2的化合物，其中R 2表示氢原子，1至3个碳原子的烷基或酰基 1至3个碳原子的基团，并且R 1具有与R相同的含义或氢原子，是新的并且适合作为用于测量酶反应中的H 2 O 2形成的色原体。

78. 发明授权

US4555479A Color photographic light-sensitive material 失效
标题翻译：彩色摄影感光材料
公开(公告)号：US4555479A
公开(公告)日：1985-11-26
申请号：US614091
申请日：1984-05-25
申请人： Nobuo Sakai , Masaki Okazaki , Yoshio Inagaki
发明人： Nobuo Sakai , Masaki Okazaki , Yoshio Inagaki
IPC分类号： G03C7/26 , C07D231/46 , C07D231/48 , C07D235/30 , C07D239/42 , C07D251/46 , C07D251/50 , C07D251/70 , C07D253/06 , C07D263/46 , G03C7/30 , G03C7/38 , G03C7/384 , G03C7/392 , G03C7/40
CPC分类号： C07D231/48 , C07D251/50 , C07D251/70 , G03C7/3012 , G03C7/38 , G03C7/3924
摘要： A silver halide color photographic light-sensitive material comprising a support having coated thereon at least one silver halide emulsion layer, the color photographic light-sensitive material having at least one layer containing at least one 2-equivalent magenta coupler of the 5-pyrazolone type represented by the following general formula (I): ##STR1## wherein W represents a phenyl group substituted with at least one substituent selected from the group consisting of a halogen atom, an alkyl group, an alkoxy group, an alkoxycarbonyl group and a cyano group; Y represents an acylamino group or an anilino group; and Z represents a group capable of being released upon coupling, and at least one compound represented by the following general formula (II): ##STR2## wherein R.sup.1 and R.sup.2, which may be the same or different, each represents a hydrogen atom, an alkyl group or an aryl group, provided that both R.sup.1 and R.sup.2 do not represent hydrogen atoms at the same time; Z.sup.1 represents a methine group, a substituted machine group or the group --N.dbd.; and Q represents an atomic group which contains a nitrogen atom, a sulfur atom or an oxygen atom and is necessary to form a 5-membered or a 6-membered heterocyclic ring together with the group ##STR3## The silver halide color photographic light-sensitive material can provide an excellent magenta color image without the occurrence of stain, even when the color photographic material is processed in a processing solution under the running condition.
摘要翻译：一种卤化银彩色摄影感光材料，其包含在其上涂覆有至少一个卤化银乳剂层的载体，所述彩色照相感光材料具有至少一层含有5-吡唑啉酮型至少一种2-当量品红成色剂由以下通式（I）表示：其中W表示被至少一个选自卤素原子，烷基，烷氧基，烷氧基羰基和氰基的取代基取代的苯基 ; Y代表酰氨基或苯胺基; Z表示能够在偶合时释放的基团，以及至少一种由以下通式（II）表示的化合物：其中R 1和R 2可以相同或不同，各自表示氢原子，烷基或芳基，条件是R 1和R 2不同时表示氢原子; Z 1表示次甲基，取代的基团或基团-N =; 并且Q表示含有氮原子，硫原子或氧原子的原子团，并且与基团一起形成5元或6元杂环是必需的。卤化银彩色照相感光即使在运行状态下在处理溶液中处理彩色照相材料，材料也可以提供优异的品红色图像而不发生污点。

79. 发明授权

US4438128A Cardioactive aryloxypropanolamines 失效
公开(公告)号：US4438128A
公开(公告)日：1984-03-20
申请号：US273543
申请日：1981-06-15
申请人： Fritz Wiedemann , Wolfgang Kampe , Karl Dietmann , Gisbert Sponer
发明人： Fritz Wiedemann , Wolfgang Kampe , Karl Dietmann , Gisbert Sponer
IPC分类号： A61K31/38 , A61K31/045 , A61K31/135 , A61K31/138 , A61K31/40 , A61K31/41 , A61K31/415 , A61K31/435 , A61K31/47 , A61K31/472 , A61K31/473 , A61K31/495 , A61K31/498 , A61K31/50 , A61K31/505 , A61K31/52 , A61K31/522 , A61P9/00 , A61P9/04 , C07C217/32 , C07C217/72 , C07C217/78 , C07C219/06 , C07C219/08 , C07C219/14 , C07D209/48 , C07D213/74 , C07D215/46 , C07D217/22 , C07D219/12 , C07D231/06 , C07D231/20 , C07D231/32 , C07D231/38 , C07D231/46 , C07D231/52 , C07D231/56 , C07D237/20 , C07D239/42 , C07D239/54 , C07D239/545 , C07D239/557 , C07D239/56 , C07D239/84 , C07D239/95 , C07D241/44 , C07D249/18 , C07D333/36 , C07D473/16 , C07D473/32 , C07D473/34 , C07D487/00 , C07D487/04 , C07D231/54
CPC分类号： C07D473/16 , C07D209/48 , C07D213/74 , C07D215/46 , C07D217/22 , C07D219/12 , C07D231/06 , C07D231/20 , C07D231/32 , C07D231/38 , C07D231/52 , C07D231/56 , C07D237/20 , C07D239/42 , C07D239/545 , C07D239/557 , C07D239/56 , C07D239/84 , C07D239/95 , C07D333/36 , C07D473/34 , C07D487/04
摘要： The present invention provides aryloxypropanolamines of the general formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be the same or different, are hydrogen or halogen atoms or lower alkyl, cyano, carboxamido, hydroxyl, lower acyloxy, lower alkoxy, lower alkenyloxy or aryl lower alkoxy radicals, R.sub.5 and R.sub.6, which may be the same or different, are hydrogen atoms or lower alkyl radicals, X is a straight or branched alkylene chain containing 2 to 6 carbon atoms, A is a mono-, bi- or tricyclic heteroaromatic or hydroheteroaromatic radical or, when at least one of the symbols R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is other than a hydrogen atom, may also be a phenyl radical, with the proviso that when A is a uracil-6-yl radical, the 5-position of the uracil moiety does not contain a hydrogen atom, R.sub.7, R.sub.8, R.sub.9, R.sub.10 and R.sub.11, which may be the same or different, are mono- or divalent substituents selected from hydrogen, halogen, nitro, hydroxylamino, amino, lower acylamino, lower alkylamino, di-(lower alkyl)-amino, hydroxyethylamino, di-(hydroxyethyl)-amino, hydroxyl, lower alkoxy, allyloxy, methoxy lower alkoxy, cyano, carboxamido, carboxy, lower alkoxycarbonyl, hydroxymethyl, lower alkoxymethyl, halomethyl, aminomethyl, lower acylaminomethyl, di-(lower alkyl)-aminomethyl, pyrrolidinomethyl, piperidinomethyl, di-(hydroxyethyl)-aminomethyl, morpholinomethyl, piperazinomethyl, 4-lower acylpiperazinomethyl, 4-lower alkylpiperazinomethyl, lower alkyl, lower alkenyl, 2-cyanoethyl, 2-(lower alkoxycarbonyl)-ethyl, 2-carboxyethyl, 2-hydroxyethyl, phenyl lower alkyl and phenyl, the phenyl radicals being optionally substituted with 1 or 2 hydroxyl or methoxy radicals, or from oxygen or sulphur; the optically-active forms and the racemic mixtures thereof, and the pharmacologically compatible salts thereof.The present invention also provides processes for the preparation of these compounds and pharmaceutical compositions containing them.

80. 发明授权

US4273855A Photographic diffusion transfer process and material for the production of color images and suitable compounds therefor 失效
标题翻译：摄影扩散转移过程和用于生产彩色图像的材料及其合适的化合物
公开(公告)号：US4273855A
公开(公告)日：1981-06-16
申请号：US19582
申请日：1979-03-12
申请人： Jan Jaeken , Andre Verhecken , Hans Vetter , Paul Marx
发明人： Jan Jaeken , Andre Verhecken , Hans Vetter , Paul Marx
IPC分类号： G03C7/00 , C07C205/37 , C07D209/14 , C07D209/42 , C07D231/46 , G03C8/10 , G03C8/14 , G03C1/40 , G03C1/10 , G03C5/54
CPC分类号： G03C8/10 , C07C205/37 , C07D209/42 , C07D231/46
摘要： A compound of the following formula and use of this compound in a photographic material and a photographic diffusion transfer process for the production of color images: ##STR1## wherein R represents a hydrogen atom or an alkyl group with 1 to 4 C atoms;A represents an oxyalkylene group, such as --CH.sub.2 --CH.sub.2 --O--;n represents 1 or 2;X represents a residue of a dye or a dye precursor, which either directly or by means of an intermediate link Z is linked to the SO.sub.2 -group;Z represents an alkylene group of 1 to 6 C atoms, an arylene group, or a heterocyclic group, which is linked to the residue X either directly or by means of --O--, --S--, --SO.sub.2 --, --NR-- (R being hydrogen or an alkyl group), --CO--, --CO--NH--, or --SO.sub.2 --NH--;R.sup.1 represents --OR.sup.2, --SR.sup.2 or ##STR2## R.sup.2 being hydrogen, an alkyl group with 1 to 22 C atoms, a cycloalkyl group or an aryl group wherein said alkyl, cycloalkyl and aryl groups may be further substituted, R.sup.3 being one of the residues defined under R.sup.2 or being an acyl residue, which is derived from an aliphatic or aromatic carboxylic or sulphonic acid, and R.sup.4 being hydrogen or optionally a substituted alkyl group with 1 to 22 C atoms.
摘要翻译：下列化合物和该化合物在照相材料中的用途以及用于制备彩色图像的照相扩散转移方法：其中R表示氢原子或具有1至4个C原子的烷基; A表示氧化烯基，例如-CH 2 -CH 2 -O-; n表示1或2; X表示染料或染料前体的残基，其直接地或通过中间链接Z连接到SO 2基团; Z表示1〜6个碳原子的亚烷基，亚芳基或杂环基，其直接或通过-O - ， - S - ， - SO 2 - ， - NR-（ R为氢或烷基），-CO - ， - CO-NH-或-SO 2 -NH-; R 1表示-OR 2，-SR 2或R 2为氢，具有1至22个C原子的烷基，环烷基或芳基，其中所述烷基，环烷基和芳基可以被进一步取代，R 3是在R2下定义的或作为酰基残基的残基，其衍生自脂族或芳族羧酸或磺酸，R4为氢或任选取代的具有1至22个C原子的烷基。

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