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71. 发明申请

US20110212050A1 SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS 有权
标题翻译：用于医疗应用的侧链可结晶聚合物
公开(公告)号：US20110212050A1
公开(公告)日：2011-09-01
申请号：US13101499
申请日：2011-05-05
申请人： Donald K. Brandom , Joan Zeltinger , Eric V. Schmid , Joseph J. Mallon
发明人： Donald K. Brandom , Joan Zeltinger , Eric V. Schmid , Joseph J. Mallon
IPC分类号： A61K31/785 , C08G77/24 , C08F212/14 , C08G63/685 , A61P29/00 , A61P17/02 , A61P35/00
CPC分类号： C08G64/10 , A61B17/12022 , A61B17/12036 , A61B17/12145 , A61B17/12186 , A61K31/74 , A61K33/18 , A61K45/06 , A61K49/0442 , A61K49/0476 , A61L24/0042 , A61L31/148 , A61L31/18 , C08F220/18 , C08G63/68 , C08G63/6826 , C08G63/6856 , C08G63/6886 , C08G63/916 , C08G64/12 , C08G64/42 , C08G65/40 , C08G77/24 , C08G2261/126 , A61K2300/00
摘要： Inherently radiopaque side-chain crystallizable polymers (IRSCCP's) are useful in various medical applications. An example of a IRSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer, the heavy atoms being present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes a IRSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product.
摘要翻译：固有的不透射线的侧链可结晶聚合物（IRSCCP）可用于各种医疗应用。 IRSCCP的实例是包含主链，多个可结晶侧链和连接到聚合物上的多个重原子的聚合物，重原子以有效使聚合物不透射线的量存在。包括IRSCCP的聚合物材料可以制造成用于至少部分地封闭体腔的医疗装置。例如，这种医疗装置可以是电疗产品。

72. 发明授权

US08008405B2 Method of stabilizing metal pigments against gassing 有权
标题翻译：稳定金属颜料对气体的方法
公开(公告)号：US08008405B2
公开(公告)日：2011-08-30
申请号：US12190279
申请日：2008-08-12
申请人： Cathy A. Taylor , Daniel Rardon , Paul Lamers , Kapiappa G. Ragunathan , Shanti Swarup , Michael Hart
发明人： Cathy A. Taylor , Daniel Rardon , Paul Lamers , Kapiappa G. Ragunathan , Shanti Swarup , Michael Hart
IPC分类号： C08G59/14 , C08G63/685 , C08G63/692
CPC分类号： C08G59/4071 , C08G59/4014 , C08G59/423 , C09D5/103 , C09D163/00 , Y10T428/2998
摘要： The present invention is directed to a passivating material suitable for passivating a metal surface. The passivating material comprises a polymer which comprises (a) at least one nitro group, and/or pyridine group, and/or phenolic hydroxyl group; and (b) at least one group selected from a phosphorous-containing group and/or a carboxylic acid group, wherein the at least one phosphorous-containing group is selected from a phosphate, a phosphite, or a non-nitrogen substituted phosphonate.
摘要翻译：本发明涉及一种适用于钝化金属表面的钝化材料。钝化材料包括聚合物，其包含（a）至少一个硝基和/或吡啶基和/或酚羟基; 和（b）选自含磷基团和/或羧酸基团中的至少一个基团，其中所述至少一种含磷基团选自磷酸酯，亚磷酸酯或非氮取代的膦酸酯。

73. 发明申请

US20110160426A1 HYDROLYTICALLY DECOMPOSABLE IONIC COPOLYMERS 有权
标题翻译：水解非离子型离子共聚物
公开(公告)号：US20110160426A1
公开(公告)日：2011-06-30
申请号：US12937631
申请日：2009-04-09
申请人： Andreas Greiner , Seema Agarwal , Thomas Kissel , Liqun Ren
发明人： Andreas Greiner , Seema Agarwal , Thomas Kissel , Liqun Ren
IPC分类号： C08G63/685 , C08G63/68 , C08G75/24 , C08G63/692 , C09J167/00 , B82Y40/00
CPC分类号： C08L101/16 , C08F8/44 , C08F216/38 , C08F220/14 , C08F220/34 , C08F2800/10 , C08F120/34
摘要： The invention at hand provides hydrolytically degradable ionic copolymers. These ionic copolymerizates are composed of one cyclic ketene acetal A, one anionic or cationic methacrylic acid derivative B, selected from 2-methyl-methacrylate, [2-(2-methyl-1-methylene-allyloxy)]ethanesulfonate, [2-(2-methyl-1-methylene-allyloxy)ethyl]phosphonate or a quaternary amine of the N,N-dimethylaminoethylmethacrylic acid (DMAEMA) and, optionally, a neutral methacrylic acid derivative C.The hydrolytically degradable anionic copolymers according to the present invention are produced by polymerizing the components A, B and C in the presence of a radical initiator under inert gas atmosphere and subsequent purification.All copolymers according to the present invention are hydrolytically degradable. Copolymers comprising a maximum of 40 mol-% of ester groups in the backbone are additionally biodegradable, wherein in the case of cationic copolymers a maximum of 20 mol-% of quaternized DMAEMA is allowed to be available.Cationic copolymers comprising at least 50 mol-% of the component B are antimicrobial.Both anionic as well as cationic copolymers are suitable for producing nanoparticles. Cationic copolymers are suitable for being used as superhydrophobic materials as well as adhesives. Anionic copolymers are suitable for biodegradable thermoplastic elastomers and for biodegradable ionomers.
摘要翻译：本发明提供了可水解降解的离子共聚物。这些离子共聚物由选自2-甲基 - 甲基丙烯酸酯，[2-（2-甲基-1-亚甲基 - 烯丙氧基）]乙磺酸酯，[2-（2-甲基-1-亚甲基 - 烯丙氧基）]乙磺酸的一种环状烯酮缩醛A，一种阴离子或阳离子甲基丙烯酸衍生物B组成， 2-甲基-1-亚甲基 - 烯丙氧基）乙基]膦酸酯或N，N-二甲基氨基乙基甲基丙烯酸（DMAEMA）和任选的中性甲基丙烯酸衍生物C的季胺。根据本发明的可水解降解的阴离子共聚物是通过在惰性气体气氛下在自由基引发剂的存在下将组分A，B和C聚合并随后纯化而制备。根据本发明的所有共聚物都是可水解降解的。在主链中包含最多40mol％的酯基的共聚物另外是可生物降解的，其中在阳离子共聚物的情况下，允许最多20mol％的季铵化DMAEMA可用。包含至少50mol％的组分B的阳离子共聚物是抗微生物剂。阴离子和阳离子共聚物都适用于生产纳米颗粒。阳离子共聚物适合用作超疏水材料以及粘合剂。阴离子共聚物适用于可生物降解的热塑性弹性体和可生物降解的离聚物。

74. 发明授权

US07928180B2 Biodegradable polymer, production method thereof, molded product thereof, and use thereof 有权
标题翻译：可生物降解聚合物及其制备方法及其用途
公开(公告)号：US07928180B2
公开(公告)日：2011-04-19
申请号：US11988008
申请日：2006-06-28
申请人： Manabu Shimoda , Tomoyuki Kawabata , Tadahito Nobori , Makoto Sukegawa
发明人： Manabu Shimoda , Tomoyuki Kawabata , Tadahito Nobori , Makoto Sukegawa
IPC分类号： C08G18/08 , C08G18/28 , C08G63/685
CPC分类号： C08G63/91 , C08G63/912 , C08G73/02 , C08G73/0206 , C08G73/028 , C08L101/16 , Y10T442/60
摘要： The problem of the invention is to provide a novel biodegradable polymer without water solubility (hygroscopicity), but with moldability and excellent water disintegratability and biodegradability, a production method thereof, a molded product thereof and applications thereof. The biodegradable polymer of the invention is a biodegradable polymer having one or more imine bonds within a molecule, characterized in that the imine bond constitutes part of a main chain structure of the biodegradable polymer. The biodegradable polymer preferably comprises a biodegradable unit and an imine unit having one or more imine bonds and has a chemical structure, in which the biodegradable units are linked by the imine unit.
摘要翻译：本发明的问题是提供一种不具有水溶性（吸湿性）但具有成型性和优异的水分解性和生物降解性的新型可生物降解聚合物，其制备方法，其成型产品和应用。本发明的可生物降解的聚合物是在分子内具有一个或多个亚胺键的可生物降解的聚合物，其特征在于亚胺键构成可生物降解的聚合物的主链结构的一部分。生物可降解聚合物优选包含可生物降解的单元和具有一个或多个亚胺键并具有化学结构的亚胺单元，其中可生物降解单元通过亚胺单元连接。

75. 发明申请

US20110027379A1 Oligo-Ethylene Glycol-Based Polymer Compositions and Methods of Use 审中-公开
标题翻译：低聚 - 乙二醇基聚合物组合物和使用方法
公开(公告)号：US20110027379A1
公开(公告)日：2011-02-03
申请号：US12746500
申请日：2008-12-04
申请人： Chih-Chang Chu , Ramaz Katsarava , Zaza D. Gomurashvili , William G. Turnell
发明人： Chih-Chang Chu , Ramaz Katsarava , Zaza D. Gomurashvili , William G. Turnell
IPC分类号： A61K9/14 , A61K47/34 , C08G63/685 , B32B5/00 , A61P35/00 , A61P29/00 , B82Y5/00
CPC分类号： A61K9/19 , A61K9/0024 , A61K9/006 , A61K9/10 , A61K9/1075 , A61K9/5146 , A61K9/7007 , A61K47/34 , A61K47/59 , A61K47/593 , A61K47/595 , C08G69/40 , C08G69/44 , C08L77/06 , C08L77/12 , Y10T428/2982
摘要： The invention provides biodegradable PEAs, PEURs and PEUs that are synthesized by solution polycondensation to include α-amino acids and oligo-ethylene ether segments in the polymer backbone. The polymers can be obtained by substituting oligo-ethylene glycol (OEG) for aliphatic di-acid and diols during their fabrication. Also provided are compositions in which bioactive agents are dispersed in the polymers. The compositions biodegrade by enzymatic action to release incorporated bioactive agents and oligo-ethylene glycol segments, which are fully biodegradable at a molecular weight less than 400 Da. Due to their comparatively rapid surface enzymatic hydrolysis, the compositions can be used to deliver bioactive agents in a controlled manner within a relatively rapid delivery time, such as about 18 to 24 hours.
摘要翻译：本发明提供通过溶液缩聚合成的可生物降解PEAs，PEUR和PEU，以在聚合物主链中包括α-氨基酸和低聚乙烯醚链段。聚合物可以通过在其制备过程中用低聚乙二醇（OEG）代替脂族二酸和二醇来获得。还提供了生物活性剂分散在聚合物中的组合物。组合物通过酶促作用生物降解以释放引入的生物活性剂和低聚乙二醇片段，其在分子量小于400Da时是完全可生物降解的。由于其相对快速的表面酶水解，组合物可用于以相对快速的递送时间（例如约18至24小时）以受控的方式递送生物活性剂。

76. 发明申请

US20090291222A1 Ethylene tetrafluoroethylene (meth)acrylate copolymers 失效
标题翻译：乙烯四氟乙烯（甲基）丙烯酸酯共聚物
公开(公告)号：US20090291222A1
公开(公告)日：2009-11-26
申请号：US12154082
申请日：2008-05-20
申请人： Weiming Qiu , Anilkumar Raghavanpillai , Peter Michael Murphy , Jessica Louise Flatter
发明人： Weiming Qiu , Anilkumar Raghavanpillai , Peter Michael Murphy , Jessica Louise Flatter
IPC分类号： B05D1/02 , C08G16/00 , C08G63/06 , C08G12/00 , C08G18/71 , C08G75/00 , C08G63/682 , B05D1/18 , B05D1/28 , C08F214/18 , C08L75/06 , C08G63/685 , C08L33/04 , C08L77/00
CPC分类号： C08F14/18 , C08F220/24 , C08F220/34 , C08F220/36 , C08F220/38 , C09D133/16 , C09D133/26 , Y10T428/2395 , Y10T428/23986 , Y10T428/3154
摘要： A copolymer composition comprising monomers copolymerized in the following percentages by weight: (a) from about 20% to about 95% of a monomer, or mixture of monomers, of formula (I): CnF2n+1(CH2)x[(CF2CF2)y(CH2CH2)z]m-L-C(O)—C(R)═CH2 (I) wherein R is H, Cl, F or CH3, L is O, S, NH, S—(CH2)rO, S—(CH2)rNH, OC(O)NH—CH2CH2O, NHC(O)NHCH2CH2O, S—(CH2)rOC(O)NHCH2CH2O, or S(CH2)rNHC(O)NHCH2CH2O, and (b) from about 5% to about 80% of at least one of: (i) an alkyl (meth)acrylate monomer having a linear, branched or cyclic alkyl group of from about 6 to about 18 carbons; or (II) a monomer of formula (II) (R2)2N—R3—O—C(O)—C(R)═CH2 (II) wherein R is H, Cl, F or CH3, each R2 is independently a C1 to C4 alkyl; and R3 is a divalent linear or branched C1 to C4 alkylene; and wherein the nitrogen is from about 40% to 100% salinized; or (iii) a mixture thereof.
摘要翻译：共聚物组合物，其包含以以下重量百分比共聚的单体：（a）约20％至约95％的式（I）的单体或单体混合物：CnF2n + 1（CH2）x [（CF2CF2）其中R为H，Cl，F或CH 3，L为O，S，NH，S-（CH 2）r O，S-（CH 2））R NH，OC（O）NH-CH 2 CH 2 O，NHC（O）NHCH 2 CH 2 O，S-（CH 2）r OC（O）NHCH 2 CH 2 O或S（CH 2）r NHC（O）NHCH 2 CH 2 O，和（b）约5％％的至少一种：（i）具有约6至约18个碳原子的直链，支链或环状烷基的（甲基）丙烯酸烷基酯单体; 或（II）式（II）的单体（R2）2N-R3-OC（O）-C（R）-CH2（Ⅱ）其中R是H，Cl，F或CH3，每个R2独立地是C1至 C4烷基; 并且R 3是二价直链或支链C1至C4亚烷基; 并且其中所述氮为约40％至100％盐碱化; 或（iii）其混合物。

77. 发明申请

US20090286904A1 POLYAMIC ACIDS DOPE COMPOSITION, PREPARATION METHOD OF HOLLOW FIBER USING THE SAME AND HOLLOW FIBER PREPARED THEREFROM 审中-公开
标题翻译：聚酰亚胺组合物，使用其的中空纤维的制备方法和其制备的中空纤维
公开(公告)号：US20090286904A1
公开(公告)日：2009-11-19
申请号：US12248294
申请日：2008-10-09
申请人： Young-Moo LEE , Sang-Hoon Han , Chul-Ho Jung , Ho-Bum Park
发明人： Young-Moo LEE , Sang-Hoon Han , Chul-Ho Jung , Ho-Bum Park
IPC分类号： C08L5/08 , C08G63/685 , C08L5/02 , C08G73/10 , C08G16/00 , C08K3/00 , C08K5/05
CPC分类号： B01D69/08 , B01D53/22 , B01D63/021 , B01D69/087 , B01D71/64 , B01D2256/12 , B01D2256/16 , B01D2256/18 , B01D2256/22 , B01D2257/102 , B01D2257/702 , B01D2325/02 , C08G73/1039 , C08G73/1042 , C08G73/1046 , C08G73/105 , C08G73/1053 , C08G73/1067 , C08G73/1071 , C08G73/22 , C08G75/32 , C08L79/04 , C08L79/08 , C08L81/00 , C08L2205/05 , D01D5/06 , D01D5/24 , D01D10/02 , D01F6/74 , Y02C20/20 , Y10T428/2938 , Y10T428/2969 , Y10T428/2975
摘要： Disclosed herein are a polyamic acid dope solution composition, a method for preparing a hollow fiber using the composition and a hollow fiber prepared by the method. More specifically, disclosed are a method for preparing a hollow fiber, comprising preparing a polyamic acid dope solution composition comprising polyhydroxyamic acid, polythiolamic acid or polyaminoamic acid, spinning the composition to prepare a hollow fiber, and imidizing and thermally rearranging the hollow fiber, and the hollow fiber prepared by the method.In accordance with the method, a hollow fiber made of a high free volume polymer membrane can be prepared by spinning the dope solution composition to prepare a hollow fiber and thermally rearranging the hollow fiber via thermal treatment. The hollow fiber thus prepared exhibits excellent gas permeability and selectivity, thus being suitable for use as a gas separation membrane.
摘要翻译：本文公开了聚酰胺酸涂料溶液组合物，使用该组合物制备中空纤维的方法和通过该方法制备的中空纤维。更具体地，公开了一种中空纤维的制备方法，其包括制备包含聚羟基胺酸，多硫代胺酸或聚氨基酰胺酸的聚酰胺酸涂料溶液组合物，纺丝所述组合物以制备中空纤维，以及中空纤维的酰亚胺化和热重排，以及通过该方法制备的中空纤维。根据该方法，可以通过纺丝掺杂溶液组合物制备中空纤维并通过热处理热中和重新排列中空纤维，由高自由体聚合物膜制成的中空纤维。由此制备的中空纤维具有优异的气体渗透性和选择性，因此适合用作气体分离膜。

78. 再颁专利

USRE40840E1 System for the contained transfer of particulates 有权
标题翻译：包含颗粒物转移系统
公开(公告)号：USRE40840E1
公开(公告)日：2009-07-07
申请号：US11280932
申请日：2005-11-17
申请人： Steven M. Lloyd , Craig R. Scheir , Lewis R. Dickerson , Donald R. Cohee , David S. Burnham , Tony R. McKee , Charles R. Sandy
发明人： Steven M. Lloyd , Craig R. Scheir , Lewis R. Dickerson , Donald R. Cohee , David S. Burnham , Tony R. McKee , Charles R. Sandy
IPC分类号： C08G63/685
CPC分类号： B65B1/28 , B65B31/024 , B65B39/007 , B65B69/0083 , B65D88/1668 , B65G69/183
摘要： An economical and reliable system for the contained transfer of particulates by means of a series of transfer containers facilitates the particulate transfer without either exposure of the operating personnel and the environment to the particulate, or environmental contamination of the particulate itself. The system employs a multiple o-ring canister assembly which can be attached to either the discharging port or charging port of a piece of processing equipment. The canister has a series of circumferential o-ring grooves which allows the attachment of a series of individual transfer containers. In a charging mode, once the particulate is charged to the processing equipment, a first transfer container is collapsed and a second transfer container is placed in the next o-ring groove, thereby containing the remaining contaminated section of the first transfer container. The first transfer container is removed through a bag-out sleeve which is an integral part of the second transfer container. The process is repeated in a stepwise fashion by moving to the next groove in the canister until the process equipment is completely charged in a particulate contained manner.
摘要翻译：用于通过一系列转移容器容纳的颗粒物转移的经济可靠的系统有助于颗粒物转移，而不会将操作人员和环境暴露于颗粒状物或颗粒本身的环境污染。该系统采用多个O形环罐组件，其可以附接到一件加工设备的排放口或装料口。罐具有一系列周向O形环槽，其允许连接一系列单独的转运容器。在充电模式中，一旦颗粒物被装入处理设备中，第一转移容器就被折叠并且第二转移容器被放置在下一个O形环槽中，从而容纳第一转移容器的剩余污染部分。第一转移容器通过作为第二转移容器的组成部分的袋出口套筒移除。通过移动到罐中的下一个槽，以逐步的方式重复该过程，直到过程设备以包含粒子的方式完全充电。

79. 发明申请

US20090068124A1 NOVEL HETEROCYCLIC SUBSTITUTED CONDENSATION POLYMERS 有权
标题翻译：新型杂环取代聚合聚合物
公开(公告)号：US20090068124A1
公开(公告)日：2009-03-12
申请号：US12281063
申请日：2007-02-23
申请人： Raphael Beumer , Franciscus Derks , Christine Mendrok
发明人： Raphael Beumer , Franciscus Derks , Christine Mendrok
IPC分类号： A61K8/88 , C08G63/685 , A61Q17/04 , A61Q11/00 , A61Q15/00 , A61Q19/10 , A61Q5/02
CPC分类号： A61K8/046 , A61K8/85 , A61K8/88 , A61K2800/5426 , A61K2800/57 , A61Q1/02 , A61Q3/02 , A61Q5/006 , A61Q5/008 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q19/00 , C08G69/44 , C11D3/3719
摘要： The invention relates to novel optionally quaternized or protonated condensation polymers having at least one heterocyclic end-group connected to the polymer backbone through a unit derived from an alkylamide, the connection comprising an optionally substituted ethylene group and to the use thereof in body care products and household products.
摘要翻译：本发明涉及新颖的具有季铵化或质子化的缩合聚合物，其具有通过衍生自烷基酰胺的单元连接至聚合物主链的至少一个杂环端基，该连接包含任选取代的亚乙基以及其在身体护理产品中的用途，以及家庭用品。

80. 发明申请

US20080262192A1 Amino Group-Containing Water-Soluble Copolymer 有权
标题翻译：含氨基的水溶性共聚物
公开(公告)号：US20080262192A1
公开(公告)日：2008-10-23
申请号：US11721768
申请日：2005-12-13
申请人： Atsuro Yoneda
发明人： Atsuro Yoneda
IPC分类号： C08G63/685 , C08G73/02 , C08G75/00
CPC分类号： C02F1/56 , C02F5/10 , C08F216/1458 , C08F220/06 , C11D3/0036 , C11D3/3769 , C11D3/3773 , D06M15/347
摘要： To provide an amino group-containing water-soluble copolymer having a high chelating performance and clay dispersancy and a method of producing the amino-group containing water-soluble copolymer efficiently and with high productivity. A water-soluble polymer containing an amino group-containing monomer unit, wherein the water-soluble polymer has a molecular weight distribution of 12 or less, and a method of producing the water-soluble polymer according to any one of claims 1 to 4, wherein the method comprises a step of polymerizing an amino group-containing allyl monomer using an initiator containing a heavy metal ion and sulfurous acid (sulfite), hydrogensulfite or hydrogen peroxide.
摘要翻译：提供具有高螯合性能和粘土分散性的含氨基的水溶性共聚物和有效且高生产率地制备含氨基的水溶性共聚物的方法。 4.一种含有氨基单体单元的水溶性聚合物，其中所述水溶性聚合物的分子量分布为12以下，以及权利要求1〜4中任一项所述的水溶性聚合物的制造方法，其中所述方法包括使用含有重金属离子和亚硫酸（亚硫酸盐），亚硫酸氢盐或过氧化氢的引发剂使含氨基的烯丙基单体聚合的步骤。

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