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71. 发明申请

US20140112843A1 AUTOMATED PELLETIZED SAMPLE DECANTING APPARATUS AND METHODS 有权
标题翻译：自动化样品取样装置及方法
公开(公告)号：US20140112843A1
公开(公告)日：2014-04-24
申请号：US13657633
申请日：2012-10-22
申请人： QIAGEN GAITHERSBURG, INC.
发明人： Bradley Scott Thomas , Brian Austin Self , Andrew Leonard , Bert Jungheim , Eric Schneider , Franklin Regan , Bowen Cui , Shubing Liu
IPC分类号： G01N1/28
CPC分类号： G01N1/28 , B01L3/50851 , B01L3/50853 , B01L3/50855 , B01L7/00 , B01L9/06 , B01L2300/046 , B01L2300/0829 , B01L2300/1805 , G01N1/2813 , G01N35/026 , G01N2001/282 , G01N2035/00495 , G01N2035/1051
摘要： An automated sample tube decanting system having one or more decanting grippers, a decant waste receptacle, a transporter, and means for rotating the decanting gripper. Each decanting gripper has a respective holder configured to selectively mate with a respective interface on a tube strip. The one or more decanting grippers are rotatable between a first position in which the tube strip is upright and a second position in which the tube strip is inverted. The transporter is configured to move the one or more decanting grippers in a lateral direction from a starting location to a location above the decant waste receptacle.
摘要翻译：具有一个或多个倾析夹具的自动化样品管倾析系统，倾析废物容器，运输器以及用于旋转倾析夹具的装置。每个倾析夹具具有相应的保持器，其被配置为选择性地与管条上的相应接口配合。一个或多个倾析夹具可在其中管条竖立的第一位置和管条倒置的第二位置之间旋转。输送器被构造成使一个或多个倾析夹持器在从开始位置到倾析废物容器上方的位置的横向方向上移动。

72. 发明授权

US08685712B2 Apparatus for performing biochemical processing using a container with a plurality of wells and the container for the apparatus 有权
标题翻译：用于使用具有多个井的容器进行生化处理的装置和用于该装置的容器
公开(公告)号：US08685712B2
公开(公告)日：2014-04-01
申请号：US11540568
申请日：2006-10-02
申请人： Hideaki Okamoto
发明人： Hideaki Okamoto
IPC分类号： C12M1/34 , B01L7/00
CPC分类号： B01L7/00 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L2200/10 , B01L2200/142 , B01L2300/043 , B01L2300/0829 , G01N35/028 , G01N2035/0405
摘要： A biochemical processing apparatus for performing biochemical processing in a container having a plurality of wells capable of holding liquid includes an opening/closing mechanism configured to open or close a lid capable of hermetically and selectively sealing the plurality of wells.
摘要翻译：在具有能够保持液体的多个孔的容器中进行生物化学处理的生化处理装置包括：开闭机构，其构造成打开或关闭能够气密地且选择性地密封多个孔的盖。

73. 发明授权

US08658419B2 Heat transfer baffle system and uses thereof 有权
标题翻译：传热挡板系统及其用途
公开(公告)号：US08658419B2
公开(公告)日：2014-02-25
申请号：US12605329
申请日：2009-10-24
申请人： Cameron Knight
发明人： Cameron Knight
IPC分类号： C12M1/00 , C12M3/00 , F28D7/00 , F28F9/22 , B01L7/00
CPC分类号： C12M41/24 , B01J8/008 , B01J8/20 , B01J19/006 , B01J19/18 , B01J19/2405 , B01J2208/00212 , B01J2208/0084 , B01J2219/00074 , B01J2219/00085 , B01J2219/00765 , B01J2219/00768 , B01L7/00 , B01L2300/1805 , B01L2300/1838 , C12M27/20 , F28D9/0006 , F28D9/0025 , F28D2021/0022 , F28F3/005 , F28F9/0246 , F28F9/22 , F28F13/12 , F28F2009/224 , F28F2265/06
摘要： This disclosure describes an improved heat transfer system for use in reaction vessels used in chemical and biological processes. In one embodiment, a heat transfer baffle comprising two sub-assemblies adjoined to one another is provided.
摘要翻译：本公开描述了用于化学和生物过程中使用的反应容器中的改进的传热系统。在一个实施例中，提供了包括彼此相邻的两个子组件的传热挡板。

74. 发明申请

US20140011289A1 ARRANGEMENT FOR PRESERVATION OF BIOLOGICAL SAMPLES 有权
标题翻译：保存生物样本的安排
公开(公告)号：US20140011289A1
公开(公告)日：2014-01-09
申请号：US14005909
申请日：2012-03-15
申请人： Michael John Smith , Stevan Paul Tortorella
发明人： Michael John Smith , Stevan Paul Tortorella
IPC分类号： G01N1/31
CPC分类号： G01N1/312 , B01L3/5029 , B01L3/5055 , B01L7/00 , B01L2200/0678 , B01L2300/0822 , G01N1/2813 , G01N1/44 , G01N2001/2826 , G01N2001/4027 , Y10T436/2525
摘要： The invention relates to an arrangement for drying of biological samples on a sample storage substrate, comprising at least one sample storage substrate holder and at least one chemical heat pad.
摘要翻译：本发明涉及用于干燥样品存储基底上的生物样品的装置，其包括至少一个样品存储基底保持器和至少一个化学加热垫。

75. 发明授权

US08596340B1 Apparatus for heating liquid samples for analysis 有权
标题翻译：用于加热液体样品进行分析的装置
公开(公告)号：US08596340B1
公开(公告)日：2013-12-03
申请号：US12925089
申请日：2010-10-13
申请人： Jack Delaney Horn, Jr. , Ricky Wayne Barber
发明人： Jack Delaney Horn, Jr. , Ricky Wayne Barber
IPC分类号： F28D15/00 , G01N1/22 , G01N1/00
CPC分类号： G01N1/42 , B01L7/00 , B01L99/00 , B01L2300/1805 , B01L2300/1822 , B01L2300/1827 , B01L2400/0487 , F28D2021/0028 , G01N1/28 , G01N35/1009 , G01N2001/002
摘要： Heat sinks for use in assemblies for preheating liquid samples prior to their introduction into an analytical stream. The heater assemblies have a heat sink having a metallic heater block and a heating element for heating the block. The block has a basin for receiving a liquid sample and allowing heat to be transmitted from the block to the sample. A drain at the lower end of the basin allows sample in the basin to flow out of the basin. A passageway extends through the block from the drain to an exterior surface of the block and provides a conduit for sample flowing from the drain, A temperature sensor is mounted in a cavity in the block and extends into the basin to measure the temperature of sample in the basin. A temperature sensor is mounted in a cavity in the block and measures the temperature of the block.
摘要翻译：散热器用于在将液体样品引入分析流之前预热液体样品的组件。加热器组件具有散热器，其具有金属加热器块和用于加热块的加热元件。该块具有用于接收液体样品并允许热从块传输到样品的盆。盆底下的排水沟允许盆中的样品流出盆地。通道从排水口延伸穿过块体的外部表面，并提供用于样品从排水口流出的导管。温度传感器安装在块体中的空腔中并延伸到盆中以测量样品的温度盆地。温度传感器安装在块体中的空腔中，并测量块体的温度。

76. 发明授权

US08574516B2 Apparatus for insulated isothermal polymerase chain reaction 有权
标题翻译：绝缘等温聚合酶链反应装置
公开(公告)号：US08574516B2
公开(公告)日：2013-11-05
申请号：US13324383
申请日：2011-12-13
申请人： Ping-Hua Teng , Cheng Su
发明人： Ping-Hua Teng , Cheng Su
IPC分类号： B01L9/06 , C12M1/36 , C12M1/38 , C12M3/00
CPC分类号： B01L7/04 , B01L7/00 , B01L9/06
摘要： An apparatus for holding a test tube in which insulated isothermal polymerase chain reaction is performed includes a heat sink and a tube rack. The heat sink has a main body with a through hole for insertion of the test tube. The through hole has a relatively big diameter section and a relatively small diameter section located below the relatively big diameter section. The tube rack is mounted on the heat sink for insertion of the test tube. The apparatus can ensure that the temperature at the liquid level of the reaction mixture is lower than the temperature suitable for conducting the primer annealing step in the polymerase chain reaction process.
摘要翻译：用于保持绝缘等温聚合酶链式反应的试管的装置包括散热器和管架。散热器具有主体，其具有用于插入试管的通孔。通孔具有相对较大的直径部分和位于较大直径部分下方的相对小的直径部分。管架安装在散热器上，用于插入试管。该装置可以确保反应混合物的液面温度低于聚合酶链反应过程中适合进行引物退火步骤的温度。

77. 发明申请

US20130266948A1 Apparatus and Methods for Integrated Sample PReparation, Reaction and Detection 审中-公开
标题翻译：综合样本检测，反应和检测的装置和方法
公开(公告)号：US20130266948A1
公开(公告)日：2013-10-10
申请号：US13759557
申请日：2013-02-05
申请人： Dylan Hilmer Bird , Jesus Ching , Bruce A. Johnson , Keith E. Moravick , Bruce Richardson
发明人： Dylan Hilmer Bird , Jesus Ching , Bruce A. Johnson , Keith E. Moravick , Bruce Richardson
IPC分类号： C12Q1/68
CPC分类号： B01L7/52 , B01F5/12 , B01F11/0071 , B01F15/0203 , B01F15/0237 , B01F2015/0221 , B01F2215/0037 , B01L3/502 , B01L3/502715 , B01L3/50851 , B01L3/523 , B01L3/527 , B01L7/00 , B01L2200/025 , B01L2200/026 , B01L2200/028 , B01L2200/0647 , B01L2200/10 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/0627 , B01L2300/0654 , B01L2300/0672 , B01L2300/0829 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2400/0406 , B01L2400/043 , B01L2400/0478 , B01L2400/0481 , B01L2400/0622 , B01L2400/0633 , B01L2400/0644 , B01L2400/0683 , C12Q1/6806 , C12Q1/686 , G01N1/38 , G01N35/1079 , G01N2035/0436 , Y10T436/118339 , Y10T436/25375 , Y10T436/255
摘要： Cartridges for the isolation of a biological sample and downstream biological assays on the sample are provided, as are methods for using such cartridges. In one embodiment, a nucleic acid sample is isolated from a biological sample and the nucleic acid sample is amplified, for example by the polymerase chain reaction. The cartridges provided herein can also be used for the isolation of non-nucleic acid samples, for example proteins, and to perform downstream reactions on the proteins, for example, binding assays. Instruments for carrying out the downstream biological assays and for detecting the results of the assays are also provided.
摘要翻译：还提供了用于分离生物样品和样品上的下游生物测定的柱，以及使用这种盒的方法。在一个实施方案中，从生物样品中分离核酸样品，并且例如通过聚合酶链式反应扩增核酸样品。本文提供的盒还可用于分离非核酸样品，例如蛋白质，并对蛋白质进行下游反应，例如结合测定。还提供了用于进行下游生物测定和检测测定结果的仪器。

78. 发明申请

US20130266946A1 Condensate Prevention Hood 审中-公开
标题翻译：冷凝防护罩
公开(公告)号：US20130266946A1
公开(公告)日：2013-10-10
申请号：US13643948
申请日：2011-05-03
申请人： Matthias Baumgartner , Gerrit Walter , Florian Dürr , Janine Röhrs , Arne Schafrinski
发明人： Matthias Baumgartner , Gerrit Walter , Florian Dürr , Janine Röhrs , Arne Schafrinski
IPC分类号： B01F9/00 , H05B6/10 , B23P19/00 , H05B6/06
CPC分类号： B01F9/0016 , B01L7/00 , B01L2300/1805 , B23P19/00 , H05B6/06 , H05B6/10 , Y10T29/49826
摘要： The invention relates to a device for controlling the temperature of laboratory vessels, comprising at least one vessel receptacle for receiving the laboratory vessels, at least one removably designed peripheral unit, and a base unit which has a temperature control device and a mounting for placing the at least one removable peripheral unit in a defined position, characterised in that the base unit and the at least one peripheral unit each have at least one coupling element, with said elements, when the peripheral unit is placed onto the base unit in the defined position, forming at least one releasable coupled pair by which the electrical power and/or at least one signal can be transmitted.
摘要翻译：本发明涉及一种用于控制实验室容器的温度的装置，包括至少一个用于接收实验室容器的容器容器，至少一个可拆卸设计的外围单元和具有温度控制装置和安装件的基座单元，至少一个可移除的外围单元处于限定的位置，其特征在于，当所述外围单元被放置在所述基座单元上的限定位置时，所述基座单元和所述至少一个外围单元各自具有至少一个与所述元件的联接元件形成至少一个可释放的耦合对，通过该对可以传输电功率和/或至少一个信号。

79. 发明授权

US08541244B2 In situ heat induced antigen recovery and staining apparatus and method 有权
标题翻译：原位热诱导抗原回收染色装置及方法
公开(公告)号：US08541244B2
公开(公告)日：2013-09-24
申请号：US13117971
申请日：2011-05-27
申请人： Lee Angros , Thomas Lee Byers
发明人： Lee Angros , Thomas Lee Byers
IPC分类号： G01N33/566
CPC分类号： G01N1/30 , A61F7/0085 , A61F7/12 , A61F2007/0063 , A61F2007/126 , B01L7/00 , B01L7/52 , B01L2200/16 , B01L2300/0822 , B01L2300/14 , B01L2400/0478 , G01N1/28 , G01N1/312 , G01N1/44 , G01N35/00029 , G01N35/026 , G01N2035/00138 , G01N2035/0412 , Y10T436/25
摘要： Contemplated herein is an automated microscope slide antigen recovery and staining apparatus and method that features a plurality of individually operable miniaturized pressurizable reaction compartments for individually and independently processing a plurality of individual microscope slides. The apparatus preferably features independently movable slide support elements each having an individually heatable heating plate. Each slide support element preferably supports a single microscope slide. Each microscope slide can be enclosed within an individual pressurizable reaction compartment. Pressures exceeding 1 atm or below 1 atm can be created and maintained in the reaction compartment prior to, during or after heating of the slide begins. Because of the ability to pressurize and regulate pressure within the reaction compartment, and to individually heat each slide, each slide and a liquid solution or reagent thereon can be heated to temperatures that could not be obtained without the enclosed pressurized environment of the reaction compartment. A reagent dispensing strip having a plurality of reconfigurable reagent modules may also be used.
摘要翻译：本文考虑的是自动显微镜载玻片抗原恢复和染色装置和方法，其特征在于具有多个单独可操作的小型可加压反应室，用于单独和独立地处理多个单独的显微镜载玻片。该装置优选地具有各自具有可单独加热的加热板的可独立移动的滑动支撑元件。每个滑动支撑元件优选地支撑单个显微镜载玻片。每个显微镜载玻片可以封闭在单独的可加压反应室内。超过1 atm或低于1 atm的压力可以在滑块开始加热之前，期间或之后产生并保持在反应室中。由于能够对反应室内的压力进行加压和调节，并且单独地加热每个载玻片，所以每个载玻片及其上的液体溶液或试剂可被加热到在没有反应室的封闭加压环境的情况下无法获得的温度。还可以使用具有多个可重新配置的试剂模块的试剂分配条。

80. 发明申请

US20130243667A1 MULTI-SAMPLE HOLDER FOR DECOMPOSITION OR EXTRACTION 有权
标题翻译：用于分解或提取的多样品支架
公开(公告)号：US20130243667A1
公开(公告)日：2013-09-19
申请号：US13874989
申请日：2013-05-01
申请人： SCP SCIENCE
发明人： George FEILDERS , Arthur ROSS , Ghiocel POPA
IPC分类号： B01L9/00
CPC分类号： B01L9/00 , B01J19/126 , B01J2219/1209 , B01J2219/1215 , B01J2219/1218 , B01L3/5082 , B01L7/00 , B01L9/06 , B01L2300/1866 , G01N1/4044 , G01N1/44 , H05B6/806 , Y10T436/25125
摘要： There is described a sample holder for decomposition or extraction of a sample material, the sample holder comprising: a frame adapted to receive at least two open-ended sample recipients thereon for holding the sample material; and a rack cover releasably securable to the frame and comprising at least two compression caps to be positioned above the at least two open-ended sample recipients to form pressure-relief valves thereon.
摘要翻译：描述了用于分解或提取样品材料的样品架，样品架包括：适于在其上容纳至少两个用于保持样品材料的开放式样品接收器的框架; 以及可释放地固定到所述框架并且包括至少两个压缩盖的齿条盖，所述至少两个压缩帽位于所述至少两个开放式样品接收器上方以在其上形成减压阀。

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