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71. 发明申请

US20090075287A1 METHODS FOR IDENTIFYING NOVEL PESTICIDAL GENE HOMOLOGUES 审中-公开
标题翻译：鉴定新型农药基因组学的方法
公开(公告)号：US20090075287A1
公开(公告)日：2009-03-19
申请号：US12208629
申请日：2008-09-11
申请人： Andre R. Abad , Ronald D. Flannagan , Bin Hu , Billy F. McCutchen , Xiaofeng Sean Yang , Cao Guo Yu
发明人： Andre R. Abad , Ronald D. Flannagan , Bin Hu , Billy F. McCutchen , Xiaofeng Sean Yang , Cao Guo Yu
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6809 , C12Q1/689 , C12Q2541/101
摘要： Methods and compositions for identifying novel pesticidal gene homologues are provided. Specifically, the methods of the invention comprise systematically designing oligonucleotide primers that are specific for a pesticidal gene of interest and performing successive rounds of PCR amplification of nucleic acid material from a microorganism, particularly a Bacillus thuringiensis strain, to identify novel homologues of known pesticidal genes. Oligonucleotide primers that can be used to practice the present methods are further disclosed.
摘要翻译：提供了鉴定新型杀虫基因同系物的方法和组合物。具体地说，本发明的方法包括系统地设计针对目的杀虫基因特异性的寡核苷酸引物，并对来自微生物特别是苏云金芽孢杆菌属菌株的核酸材料进行连续循环的PCR扩增，以鉴定已知杀虫基因的新型同系物。进一步公开了可用于实施本方法的寡核苷酸引物。

72. 发明授权

US07475866B2 Pulling device for container inspection system 有权
标题翻译：集装箱检查系统牵引装置
公开(公告)号：US07475866B2
公开(公告)日：2009-01-13
申请号：US11284989
申请日：2005-11-22
申请人： Bin Hu , Shangmin Sun , Guang Yang , Yucheng Wu , Zhongrong Yang , Nan Jiang , Wanquan Shen , Jianjun Su
发明人： Bin Hu , Shangmin Sun , Guang Yang , Yucheng Wu , Zhongrong Yang , Nan Jiang , Wanquan Shen , Jianjun Su
IPC分类号： B66D1/26
CPC分类号： B61J3/06 , B66D1/60 , G01N9/24 , G01N35/04 , G01N2033/0081 , G01V5/0008
摘要： The present invention discloses a pulling device for a container inspection system including a pulling vehicle (1) arranged inside an inspection passage, a winch (5) and wire tension mechanisms (6,6′). Front and rear ends of the pulling vehicle are connected to a wire rope so as to drive the pulling vehicle to move back and forth inside the inspection passage. The wire rope connected to front and rear ends of the pulling vehicle is wound around a wire tension mechanism arranged at front and rear ends of the inspection passage and is turned around by a swerving pulley (2) which is positioned at the same horizontal plane as that of the wire rope, the pulling vehicle, and the wire tension mechanisms, then the wire rope passes through the vertical pulley block, and finally it is connected to a single winding drum (4) of the winch (5) and wound around the single winding drum (4) respectively. Compared with the prior arts, the present invention is advantageous in reduction in equipment investment and decrease in area occupied by the pulling device. Further, the inspection operation can be carried out more reliably and safely.
摘要翻译：本发明公开了一种用于容器检查系统的牵引装置，其包括设置在检查通道内的牵引车辆（1），绞盘（5）和线张力机构（6,6'）。牵引车辆的前端和后端连接到钢丝绳上，以驱动牵引车辆在检查通道内前后移动。连接到牵引车辆的前端和后端的钢丝绳缠绕在布置在检查通道的前端和后端的线张力机构上，并且通过位于与水平面相同的水平面的转动滑轮（2）转动，钢丝绳，牵引车辆和钢丝张力机构，则钢丝绳穿过垂直滑轮组，最后连接到绞盘（5）的单个卷绕筒（4）上并缠绕在单卷筒（4）。与现有技术相比，本发明有利于减少设备投资并减少牵引装置占用的面积。此外，可以更加可靠和安全地进行检查操作。

73. 发明申请

US20070254964A1 Ultrapure colloidal silica for use in chemical mechanical polishing applications 审中-公开
标题翻译：超纯胶体二氧化硅用于化学机械抛光应用
公开(公告)号：US20070254964A1
公开(公告)日：2007-11-01
申请号：US11818730
申请日：2007-06-15
申请人： Deepak Mahulikar , Yuhu Wang , Ken Delbridge , Gert Moyaerts , Saeed Mohseni , Nichole Koontz , Bin Hu , Liqing Wen
发明人： Deepak Mahulikar , Yuhu Wang , Ken Delbridge , Gert Moyaerts , Saeed Mohseni , Nichole Koontz , Bin Hu , Liqing Wen
IPC分类号： B01F3/12 , B08B7/00
CPC分类号： C23F3/04 , C01B33/1435 , C01B33/1485 , C01P2004/62 , C01P2004/64 , C01P2006/80 , C09G1/02 , C09K3/1463 , C09K3/1472 , H01L21/31053 , H01L21/3212
摘要： An ultrapure colloidal silica dispersion comprising colloidal silica particles having a mean or aggregate particle size from about 10 to about 200 nm, wherein the colloidal silica dispersion has less than 200 ppb of each trace metal impurity disposed therein, excluding potassium and sodium, and have less than 2 ppm residual alcohol.
摘要翻译：一种超纯胶体二氧化硅分散体，其包含平均或聚集体粒径为约10至约200nm的胶体二氧化硅颗粒，其中所述胶体二氧化硅分散体在其中排列的不含钾和钠的痕量金属杂质少于200ppb，超过2 ppm的残留酒精。

74. 发明申请

US20070094959A1 Phase-shifting masks with sub-wavelength diffractive optical elements 有权
$Phase-shifting masks with sub-wavelength diffractive optical elements$
标题翻译：具有亚波长衍射光学元件的相移掩模
公开(公告)号：US20070094959A1
公开(公告)日：2007-05-03
申请号：US11242165
申请日：2005-09-30
申请人： Bin Hu , Vivek Singh , Yan Borodovsky
发明人： Bin Hu , Vivek Singh , Yan Borodovsky
IPC分类号： E04C2/52
CPC分类号： G03F7/70283 , G03F1/32 , G03F1/36 , G03F7/70433 , G03F7/705
摘要： The present invention discloses a method of designing a set of two tiled masks, as well as, a mask including: a first tile, the first tile being transparent to a light, the first tile having a first characteristic linear dimension that is 15% or less of a wavelength of the light; a second tile, the second tile being transparent to the light, the second tile having a second characteristic linear dimension that is 15% or less of the wavelength of the light; and a third tile, the third tile being opaque to the light, the third tile having a third characteristic linear dimension that is 15% or less of the wavelength of the light.
摘要翻译：本发明公开了一种设计一组两个平铺掩模的方法，以及掩模，包括：第一瓦片，第一瓦片对于光是透明的，第一瓦片具有15％的第一特征线性尺寸或较少的波长的光; 第二瓦片，所述第二瓦片对于所述光是透明的，所述第二瓦片具有光的波长的15％或更小的第二特征线性尺寸; 以及第三瓦片，所述第三瓦片对于所述光不透明，所述第三瓦片具有光的波长的15％以下的第三特征线性尺寸。

75. 发明申请

US20070006113A1 Determining an optimizaton for generating a pixelated photolithography mask with high resolution imaging capability 审中-公开
标题翻译：确定用于产生具有高分辨率成像能力的像素化光刻掩模的优化
公开(公告)号：US20070006113A1
公开(公告)日：2007-01-04
申请号：US11173394
申请日：2005-06-30
申请人： Bin Hu , Vivek Singh , Bikram Baidya , Kenny Toh , Srinivas Bollepalli , Yan Borodovsky
发明人： Bin Hu , Vivek Singh , Bikram Baidya , Kenny Toh , Srinivas Bollepalli , Yan Borodovsky
IPC分类号： G06F17/50
CPC分类号： G03F1/36
摘要： A pixelated photolithography mask is optimized for high resolution microelectronic processing. In one embodiment, the invention includes synthesizing a pixelated photolithography mask, applying a pixel flipping function to the mask, comparing the resulting mask to a desired result, and synthesizing an optimized pixelated binary photolithography mask using the function.
摘要翻译：像素化光刻掩模被优化用于高分辨率微电子处理。在一个实施例中，本发明包括合成像素化光刻掩模，向掩模施加像素翻转函数，将所得到的掩模与期望的结果进行比较，以及使用该功能合成优化的像素化二值光刻掩模。

76. 发明授权

US6162919A Process for preparing the d-threo isomer of methylphenidate hydrochloride 有权
标题翻译：制备哌甲酯盐酸盐的d-苏式异构体的方法
公开(公告)号：US6162919A
公开(公告)日：2000-12-19
申请号：US204460
申请日：1998-12-03
申请人： Mahavir Prashad , Bin Hu
发明人： Mahavir Prashad , Bin Hu
IPC分类号： C07D211/34 , C07D211/32
CPC分类号： C07D211/34
摘要： A process for preparing the d-threo isomer of methylphenidate hydrochloride comprising converting d,l-threo methylphenidate hydrochloride to the free base form in a first step, resolving the free base prepared in the first step with (R)-(-)-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate to obtain the phosphate salt enriched with the d-threo isomer of methylphenidate in a second step, basifying the phosphate salt to obtain the free base form of the d-threo isomer of methylphenidate in a third step, converting the free base to the hydrochloride salt form of the d-threo isomer of methylphenidate in high optical purity in a fourth step, and recrystallizing the hydrochloride salt form to obtain the desired d-threo isomer in a higher optical purity. An alternative embodiment relates to the preparation of the d-threo isomer of methylphenidate hydrochloride utilizing the hydrochloride salt form of the racemic mixture of threo-methylphenidate directly.
摘要翻译：一种制备哌甲酯盐酸盐的+ E，未d + EE-同位素异构体的方法，包括在第一步中将+ E，uns d，l + EE-所述哌甲酯盐酸盐转化为游离碱形式，（R） - （ - ） - 1,1'-联萘-2,2'-二基磷酸氢盐的第一步，以获得在第二步中富含哌甲酯的+ E，未d + EE-异构体的磷酸盐在第三步中碱化磷酸盐以获得哌甲酯的+ E，未d + EE-苏氨酸异构体的游离碱形式，将游离碱转化为+ E，非d + EE-th的盐酸盐形式在第四步中高哌嗪类异构体的高光学纯度，并重结晶盐酸盐形式，以获得更高的光学纯度的所需的+ E，非d + EE-苏式异构体。替代实施方案涉及直接用盐酸盐形式的苏氨哌甲酸酯的外消旋混合物制备哌甲酯盐酸盐的+ E，未d + EE-苏氨酸异构体。

77. 发明授权

US09291579B2 Method of estimating chordal holdup values of gas, oil and water for tomographic imaging of a three-phase flow through a volume 有权
标题翻译：估算气体，油和水的弦状滞留值用于通过体积的三相流的断层成像的方法
公开(公告)号：US09291579B2
公开(公告)日：2016-03-22
申请号：US14111772
申请日：2012-04-16
申请人： Bin Hu , Christopher John Lawrence
发明人： Bin Hu , Christopher John Lawrence
IPC分类号： G01N23/04 , G01N23/12
CPC分类号： G01N23/046 , G01N23/12 , G01N2223/419 , G01N2223/601 , G01N2223/635
摘要： A method of estimating chordal holdup values of gas, oil, and water (εG, εO, εW) for tomographic imaging of a three-phase flow through a volume, including: providing an X-ray source for irradiating through said volume and X-ray sensors for discriminating between a first and a second radiation bands, conducting first calibration measurements (IGS, IOS, IWS) of said first radiation band, conducting second calibration measurements (IGH, IOH, IWH) of said second radiation band, arranging a mixture of two or more fluids, irradiating said volume and conducting X-ray measurements (IS, IH) in said radiation bands, establishing a relationship between a function of holdup values f(εG, εW) of at least gas and water and said X-ray measurements (IS, IH), searching holdup values (εG, εW) that minimize said function of holdup values f(εG, εW) under the constraints of the sum of said holdup values is more than or equal to zero and less than or equal to one, i.e. that 0≦εG+εW≦1.
摘要翻译：一种估计气体，油和水（＆Egr; G，＆egr; O，＆egr; W）的弦状滞留值用于通过体积的三相流的断层成像的方法，包括：提供用于照射的X射线源通过所述体积和X射线传感器来区分第一和第二辐射带，进行所述第一辐射带的第一校准测量（IGS，IOS，IWS），进行所述第二辐射带的第二校准测量（IGH，IOH，IWH）辐射带，布置两种或更多种流体的混合物，照射所述体积并在所述辐射带中进行X射线测量（IS，IH），建立保持值f（＆egr; G，＆egr; W）的函数之间的关系，至少气体和水以及所述X射线测量（IS，IH），搜索在约束条件下使滞留值f（＆egr; G，＆egr; W）的所述功能最小化的保持值（＆egr; G，＆egr; W）所述保持值的总和大于或等于零且小于或等于1，即tha t 0＆nlE;＆egr; G +＆egr; W＆nlE; 1。

78. 发明授权

US09122169B2 Mask layout patterns for closely spaced primitives in phase shift photolithography masks 有权
标题翻译：在相移光刻掩模中用于紧密间隔的基元的掩模布局图案
公开(公告)号：US09122169B2
公开(公告)日：2015-09-01
申请号：US13977638
申请日：2011-12-29
申请人： Bin Hu , Vivek K. Singh , Sungwon Kim , Chulwoo Oh , Mehmet E. Yavuz
发明人： Bin Hu , Vivek K. Singh , Sungwon Kim , Chulwoo Oh , Mehmet E. Yavuz
IPC分类号： G06F17/50 , G03F1/68 , G03F1/26 , G03F1/70
CPC分类号： G03F1/68 , G03F1/26 , G03F1/70
摘要： Improved mask layout patterns are described for closely spaced primitives in phase shift photolithography masks. In one example, at least a portion of a photolithography mask layout is decomposed into primitives. Jogs are identified from among the primitives, the jogs being characterized by three adjacent corners. E-fields are determined for the identified jogs and are applied to synthesize an electric field at a substrate. The mask layout is corrected using the synthesized electric field and a printed wafer pattern is calculated.
摘要翻译：在相移光刻掩模中描述了用于紧密间隔的基元的改进的掩模布局图案。在一个示例中，光刻掩模布局的至少一部分被分解为基元。从原始图像中识别出慢跑，其特征在于三个相邻角落。为识别的点动确定电场，并且被应用于在衬底处合成电场。使用合成电场校正掩模布局，并计算印刷晶片图案。

79. 发明申请

US20150057322A1 COMPOUNDS CONTAINING S-N-VALERYL-N--VALINE AND (2R,4S)-5-BIPHENYL-4-YL-4-(3-CARBOXY-PROPIONYLAMINO)-2-METHYL-PENTANOIC ACID ETHYL ESTER MOIETIES AND CATIONS 审中-公开
标题翻译：含有S-N-戊基-N-（+） - （2R，4S）-5-联苯-4-基-4-（3-羧基 - 丙酰氨基）-2-甲基 - 戊酸乙酯的化合物和方法
公开(公告)号：US20150057322A1
公开(公告)日：2015-02-26
申请号：US14311788
申请日：2014-06-23
申请人： Li Feng , Sven Erik Godtfredsen , Paul Allen Sutton , Mahavir Prashad , Michael J. Girgis , Bin Hu , Yugang Liu , Thomas J. Blacklock , Piotr Henryk Karpinski
发明人： Li Feng , Sven Erik Godtfredsen , Paul Allen Sutton , Mahavir Prashad , Michael J. Girgis , Bin Hu , Yugang Liu , Thomas J. Blacklock , Piotr Henryk Karpinski
IPC分类号： C07D207/50
CPC分类号： A61K31/216 , A61K31/41 , A61K31/4422 , A61K31/5415 , A61K45/06 , A61K2300/00 , C07C233/47 , C07D207/50 , C07D257/04
摘要： A method for treatment of a cardiovascular or renal condition or disease with a specific combination, linked pro-drug or a compound of an angiotensin receptor antagonist and a NEPi.
摘要翻译：用于特异性组合，连接的前药或血管紧张素受体拮抗剂和NEPi的化合物治疗心血管或肾脏疾病或疾病的方法。

80. 发明授权

US08877938B2 Compounds containing S-N-valeryl-N-{[2′-(1H-tetrazole-5-yl)-biphenyl-4-yl]-methyl}-valine and (2R,4S)-5-biphenyl-4-yl-4-(3-carboxy-propionylamino)-2-methyl-pentanoic acid ethyl ester moieties and cations 有权
标题翻译：含有N-戊酰基-N - {[2' - （1H-四唑-5-基） - 联苯-4-基] - 甲基} - 缬氨酸和（2R，4S）-5-联苯-4-基-4 - （3-羧基 - 丙酰基氨基）-2-甲基 - 戊酸乙酯部分和阳离子
公开(公告)号：US08877938B2
公开(公告)日：2014-11-04
申请号：US11722360
申请日：2006-11-08
申请人： Lili Feng , Sven Erik Godtfredsen , Bin Hu , Yugang Liu , Piotr Karpinski , Paul Allen Sutton , Mahavir Prashad , Michael J. Girgis , Thomas J. Blacklock
发明人： Lili Feng , Sven Erik Godtfredsen , Bin Hu , Yugang Liu , Piotr Karpinski , Paul Allen Sutton , Mahavir Prashad , Michael J. Girgis , Thomas J. Blacklock
IPC分类号： C07D257/04 , C07C233/47 , A61K31/41 , A61K31/4422 , A61K31/5415
CPC分类号： A61K31/216 , A61K31/41 , A61K31/4422 , A61K31/5415 , A61K45/06 , A61K2300/00 , C07C233/47 , C07D207/50 , C07D257/04
摘要： A compound of an angiotensin receptor antagonist (ARB), a neutral endopeptidase inhibitor (NEPi) and one or more monovalent cations are useful for the treatment of hypertension and/or heart failure. ARB includes S—N-valeryl-N-{[2′-(1H-tetrazole-5-yl)-biphenyl-4-yl]-methyl}-valine in the anion form, NEPi includes (2R,4S)-5-biphenyl-4-yl-4-(3-carboxy-propionylamino)-2-methyl-pentanoic acid ethyl ester in the anion form and cation includes monovalent cations such as Na+. The compound includes trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl)propionate-(S)-3′-methyl-2′-(pentanoyl{2″-(tetrazol-5-ylate)biphenyl-4′-ylmethyl}amino)butyrate] hemipentahydrate.
摘要翻译：血管紧张素受体拮抗剂（ARB），中性内肽酶抑制剂（NEPi）和一种或多种一价阳离子的化合物可用于治疗高血压和/或心力衰竭。 ARB包括阴离子形式的S-N-戊酰基-N - {[2' - （1H-四唑-5-基） - 联苯-4-基] - 甲基} - 缬氨酸，NEPi包括（2R，4S）-5 - 联苯-4-基-4-（3-羧基 - 丙酰基氨基）-2-甲基 - 戊酸乙酯，包括一价阳离子如Na +。该化合物包括[3 - （（1S，3R）-1-联苯-4-基甲基-3-乙氧基羰基-1-丁基氨基甲酰基）丙酸乙酯 - （S）-3'-甲基-2' - （戊酰基{2“ （四唑-5-基）联苯-4-基甲基}氨基）丁酸乙酯]半水合物。

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