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    • 75. 发明授权
    • Hydrolysis resistant vinyl lactam amino acrylamide polymers
    • 耐水解乙烯基内酰胺氨基丙烯酰胺聚合物
    • US4923694A
    • 1990-05-08
    • US236395
    • 1988-08-25
    • Jenn S. ShihTerry E. Smith
    • Jenn S. ShihTerry E. Smith
    • A61K8/72A61K8/00A61K8/81A61Q5/00A61Q5/02A61Q5/06A61Q5/12C08F20/52C08F26/10C08F220/60C08F226/06C08F226/10
    • C08F220/60A61K8/8182A61Q5/02A61Q5/12C08F226/06Y10S424/02
    • The invention relates to a hydrolysis resistant, high molecular weight polymer represented by the formula ##STR1## wherein R is alkylene having from 3 to 8 carbon atoms which is optionally substituted with lower alkyl; R.sub.1 and R.sub.2 are each hydrogen or methyl; wherein R.sub.7 and R.sub.8 are each alkylene having from 1 to 18 carbon atoms and are optionally substituted with alkyl; the sum of r and t is one or two; R.sub.4 and R.sub.5 are each independently lower alkyl; R.sub.6 is alkyl, aralkyl or alkaryl having from 1 to 8 carbon atoms or N-alkylene lactam having from 3 to 8 carbon atoms; X.sup.- is an anion derived from the group of halogen, SO.sub.3, SO.sub.4, HSO.sub.4 and R.sub.6 SO.sub.4 ; M is a copolymerizable vinyl monomer; n has a value of from 10 to 99 mole %; m has a value of from 1 to 90 mole %; p has a value of from 0 to 20 mole % and the sum of m+n+p is 100; q and q' have the same value which is 0 or 1; s is the reciprocal of the number of negative charges in X; and the total amount of monomer represented by subscript m can be from 1% to 100% quaternized. The invention also relates to a process for the preparation of the polymer containing low residual monomer and to uses of the polymer.
    • 本发明涉及由下式表示的耐水解高分子量聚合物:其中R是具有3至8个碳原子的亚烷基,其任选被低级烷基取代; R1和R2各自为氢或甲基; 其中R 7和R 8各自是具有1至18个碳原子的亚烷基并且任选被烷基取代; r和t的和为1或2; R4和R5各自独立地为低级烷基; R6是具有1至8个碳原子的烷基,芳烷基或烷芳基或具有3至8个碳原子的N-亚烷基内酰胺; X-是衍生自卤素,SO 3,SO 4,HSO 4和R 6 SO 4的阴离子的阴离子; M是可共聚的乙烯基单体; n的值为10〜99摩尔%。 m的值为1〜90摩尔%。 p的值为0〜20摩尔%,m + n + p的和为100。 q和q'具有相同的值,即0或1; s是X中的负电荷数的倒数; 并且由下标m表示的单体的总量可以为1%至100%的季铵化。 本发明还涉及制备含有低残留单体的聚合物和聚合物的用途的方法。