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71. 发明授权

US4300973A Method of adhesion of rubber to reinforcing materials 失效
标题翻译：橡胶与增强材料粘合的方法
公开(公告)号：US4300973A
公开(公告)日：1981-11-17
申请号：US162336
申请日：1980-06-23
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： C08J5/10 , C09J5/00
CPC分类号： C08J5/10 , C08J2321/00 , Y10T428/12562 , Y10T428/2944 , Y10T428/31696
摘要： A method for adhering rubber to reinforcing materials which comprises embedding a textile fiber or metal reinforcing material in a vulcanizable rubber composition comprising rubber, a vulcanizing agent and an imidazolidinone and vulcanizing said composition.
摘要翻译：一种将橡胶粘附到增强材料上的方法，包括将纺织纤维或金属增强材料包括在包含橡胶，硫化剂和咪唑啉酮的硫化橡胶组合物中并硫化所述组合物。

72. 发明授权

US4228045A Method of adhesion of rubber to reinforcing materials 失效
标题翻译：橡胶与增强材料粘合的方法
公开(公告)号：US4228045A
公开(公告)日：1980-10-14
申请号：US008204
申请日：1979-01-31
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： C08L7/00 , C07D233/40 , C08J5/10 , C08K5/07 , C08K5/3445 , C08L21/00 , C08L23/00 , C08L33/00 , C08L33/02 , C08L67/00 , C08L77/00 , C08L101/00 , C08L11/00
CPC分类号： C08J5/10 , C07D233/40 , C08K5/05 , C08K5/07 , C08K5/15 , C08K5/3445 , C08J2321/00 , Y10S524/925
摘要： A vulcanizable rubber composition comprising a rubber, a vulcanizing agent and glyoxal or a glyoxal reaction product and a method of adhering fiber or steel tire cord, are disclosed.
摘要翻译：公开了一种包含橡胶，硫化剂和乙二醛或乙二醛反应产物的可硫化橡胶组合物和粘合纤维或钢轮胎帘线的方法。

73. 发明授权

US08901347B1 Absorbable polyurethanes and methods of use thereof 有权
标题翻译：可吸收聚氨酯及其使用方法
公开(公告)号：US08901347B1
公开(公告)日：2014-12-02
申请号：US13275902
申请日：2011-10-18
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： A61K47/16 , C07C265/14 , C07C265/12 , C07C211/46 , A61K47/14
CPC分类号： C07C265/12 , A61K9/12 , A61K47/14 , A61K47/16 , A61K47/34 , A61L15/26 , A61L17/10 , A61L24/046 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/06 , A61L31/10 , A61L31/148 , C07C211/46 , C07C219/34 , C07C229/56 , C07C229/60 , C07C265/14 , C08G18/02 , C08G18/28 , C08G18/7657 , C08G63/685 , C08G69/40 , C08G69/44 , C08G2230/00 , C09D175/04 , C08L75/04 , C08L75/06 , C08L77/12 , C08L77/00
摘要： Disclosed are novel bioabsorbable and biodegradable monomer compounds, bioabsorbable and biodegradable polymers therefrom, and methods of making such monomers and polymers, which are useful in pharmaceutical delivery systems, tissue engineering applications, tissue adhesives products, implantable medical devices, foams and reticulated foams for wound healing and drug delivery, bone hemostats and bone void fillers, adhesion prevention barriers, meshes, filters, stents, medical device coatings, pharmaceutical drug formulations, consumer product and cosmetic and pharmaceutical packaging, apparel, infusion devices, blood collection tubes and devices, other medical tubes, skin care products, and transdermal drug delivery materials.
摘要翻译：公开了新的生物可吸收和可生物降解的单体化合物，其生物可吸收和可生物降解的聚合物，以及制备此类单体和聚合物的方法，其可用于药物递送系统，组织工程应用，组织粘合剂产品，可植入医疗装置，泡沫和网状泡沫用于伤口愈合和药物递送，骨止血剂和骨空隙填料，防粘连屏障，网眼，过滤器，支架，医疗器械涂层，药物制剂，消费品和化妆品和药物包装，服装，输液装置，采血管和装置医疗管，护肤品和透皮药物递送材料。

74. 发明授权

US08846845B2 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices 有权
标题翻译：用于医疗器械的生物可吸收和生物相容性聚氨酯和聚酰胺
公开(公告)号：US08846845B2
公开(公告)日：2014-09-30
申请号：US13402391
申请日：2012-02-22
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： C08G18/32 , C08G18/34 , C08G18/71 , C08G63/685 , C08G69/08
CPC分类号： A61K47/34 , A61F2/442 , A61L15/64 , A61L17/06 , A61L17/105 , A61L24/043 , A61L24/046 , A61L27/18 , A61L27/58 , A61L31/10 , A61L31/148 , C08G18/10 , C08G18/711 , C08G18/771 , C08G69/26 , C08G69/40 , C08G69/44 , C08G2230/00 , C09J175/06 , Y10T428/31681 , C08L67/04 , C08L77/00 , C08L75/04
摘要： Absorbable polyurethanes, polyamides and polyester urethanes prepared from at least one compound selected from: or the corresponding diamines or diisocyanates thereof, wherein each X independently represents —CH2COO—, —CH(CH3)COO—, —CH2CH2OCH2COO—, —CH2CH2CH2CH2CH2COO—, —(CH2)yCOO— where y is 2 to 4 or 6 to 24, or —(CH2CH2O)z′CH2COO— where z′ is 2 to 24; each Y represents —COCH2O—, —COCH(CH3)O—, —COCH2OCH2CH2O—, —COCH2CH2CH2CH2CH2O—, —CO(CH2)mO— where m is 2 to 4 or 6 to 24, or —COCH2O(CH2CH2O)n— where n is 2 to 24; R′ is hydrogen, benzyl or straight-chained or branched alkyl; p is 1 to 4; and Rn represents one or more members selected from H, alkoxy, benzyloxy, aldehyde, halogen, carboxylic acid and —NO2, which is attached directly to an aromatic ring or attached through an aliphatic chain. Absorbable polymers prepared from these compounds are useful for drug delivery, tissue engineering, tissue adhesives, adhesion prevention and other implantable medical devices.
摘要翻译：由选自以下的至少一种化合物或其相应的二胺或二异氰酸酯制备的可吸收的聚氨酯，聚酰胺和聚酯聚氨酯，其中每个X独立地表示-CH 2 COO-， - CH（CH 3）COO-， - CH 2 CH 2 OCH 2 COO-， - CH 2 CH 2 CH 2 CH 2 COO-， - （CH2）yCOO-，其中y为2至4或6至24，或 - （CH2CH2O）z'CH2COO-，其中z'为2至24; 每个Y表示-COCH 2 O-，-COCH（CH 3）O - ， - COCH 2 CH 2 CH 2 CH 2 - ， - COCH 2 CH 2 CH 2 CH 2 CH 2 O - ， - CO（CH 2）m O-，其中m为2至4或6至24，或-COCH 2 O（CH 2 CH 2 O） n为2〜24; R'是氢，苄基或直链或支链烷基; p为1〜4; 并且R n表示选自H，烷氧基，苄氧基，醛，卤素，羧酸和-NO 2中的一种或多种，其直接连接到芳环上或通过脂族链连接。由这些化合物制备的可吸收聚合物可用于药物递送，组织工程，组织粘合剂，防止粘附和其他可植入医疗器械。

75. 发明申请

US20130041045A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM 有权
标题翻译：功能性DIPHENOLICS和可吸收的聚合物
公开(公告)号：US20130041045A1
公开(公告)日：2013-02-14
申请号：US13604614
申请日：2012-09-05
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： C07C229/36 , C08G69/48 , C08G69/44 , A61K8/44 , A61K47/18
CPC分类号： A61L31/10 , A61L27/18 , A61L27/58 , A61L31/06 , A61L31/148 , C07K5/06078 , C08L67/04
摘要： The present invention relates to dephenolic compounds, an example of which is shown below, which are functionalized, and polymers formed from the same. Polymers formed from the functionalized diphenolics are expected to have controllable degradation profiles, enabling them to release an active component over a desired time range. The polymers are also expected to be useful in a variety of medical applications.
摘要翻译：本发明涉及脱模化合物，其实例如下所示，其被官能化，和由其形成的聚合物。由功能性二元酚形成的聚合物预期具有可控的降解特征，使得它们能够在期望的时间范围内释放活性组分。聚合物也预期在各种医疗应用中是有用的。

76. 发明授权

US08367108B2 Functionalized non-phenolic amino acids and absorbable polymers therefrom 有权
公开(公告)号：US08367108B2
公开(公告)日：2013-02-05
申请号：US11847042
申请日：2007-08-29
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： A61K9/00 , A61F2/00 , A61M37/00 , C07C229/02 , C08L89/00
CPC分类号： A61K47/34 , A61K9/0024 , A61L27/227 , A61L27/54 , A61L27/58 , A61L31/047 , A61L31/148 , A61L31/16 , A61L2300/00 , C07C235/12 , Y10T428/1362 , Y10T428/1397 , Y10T442/40 , Y10T442/50
摘要： The present invention relates to compound of formula I, which are functionalized, non-phenolic amino acids, and polymers formed from the same. Polymers formed from the functionalized amino acids are expected to have controllable degradation profiles, enabling them to release an active component over a desired time range. The polymers are also expected to be useful in a variety of medical applications.

77. 发明授权

US08217134B2 Controlled release of biologically active compounds 有权
标题翻译：生物活性化合物的控制释放
公开(公告)号：US08217134B2
公开(公告)日：2012-07-10
申请号：US12202939
申请日：2008-09-02
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： C08G63/02
CPC分类号： A61K47/481 , A61K8/85 , A61K8/88 , A61K31/785 , A61K45/06 , A61K47/32 , A61K47/34 , A61K2800/10 , A61L17/105 , A61L17/12 , A61L17/145 , A61L27/18 , A61L27/34 , A61L27/58 , A61L31/06 , A61L31/10 , A61L31/16 , A61Q19/00 , C07C59/70 , C07C69/63 , C07C69/736 , C07D311/36 , C08G63/16 , C08G63/672 , C08G69/40 , C08G69/44 , C08L77/12 , C08L67/04
摘要： The present invention relates to biodegradable polymers (e.g., polyesters and polyester amides) derived from functionalized biologically active compounds that can provide site specific delivery of bioactive compounds upon biodegradation in a controlled manner.
摘要翻译：本发明涉及衍生自官能化的生物活性化合物的可生物降解聚合物（例如聚酯和聚酯酰胺），其可以以受控方式在生物降解中提供生物活性化合物的位点特异性递送。

78. 发明申请

US20120094994A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM 有权
标题翻译：功能性氨基酸和可吸收的聚合物
公开(公告)号：US20120094994A1
公开(公告)日：2012-04-19
申请号：US13337074
申请日：2011-12-24
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： A61K31/5375 , A61K31/216 , C07D265/32 , C07C233/47 , C08G69/44 , C07C235/12 , A61K47/18 , A61P17/02 , A61P41/00 , C08G69/10 , C07C229/36 , A61K31/198
CPC分类号： C08G63/912 , A61L27/22 , A61L31/043 , C07C229/36 , C08G18/3821 , C08G63/685 , C08G63/6852 , C08G63/6854 , C08G63/91
摘要： The present invention relates to compounds of formula I and II, which are functionalized amino acids, and polymers formed from the same. Polymers formed from the functionalized amino acids are expected to have controllable degradation profiles, enabling them to release an active component over a desired time range. The polymers are also expected to be useful in a variety of medical applications.
摘要翻译：本发明涉及作为官能化氨基酸的式I和II化合物，以及由其形成的聚合物。由官能化氨基酸形成的聚合物预期具有可控的降解特征，使得它们能够在期望的时间范围内释放活性组分。聚合物也预期在各种医疗应用中是有用的。

79. 发明授权

US08053591B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release 有权
标题翻译：官能化生物降解三氯生单体和低聚物用于控制释放
公开(公告)号：US08053591B2
公开(公告)日：2011-11-08
申请号：US12212233
申请日：2008-09-17
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： C07C69/76
CPC分类号： C07C69/67 , A61B17/064 , A61B17/58 , A61K9/08 , A61K9/10 , A61K47/12 , A61K47/32 , A61K47/34 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/202 , A61L2300/404 , A61L2300/606 , C07C69/708 , C07C69/712 , C07C235/16
摘要： This invention relates to the discovery of functionalized triclosan monomers and oligomers that, when incorporated into a substrate of, or applied as part of a coating to, medical devices and/or consumer products may extend the duration of antimicrobial properties to the medical devices and/or consumer products.
摘要翻译：本发明涉及功能化三氯生单体和低聚物的发现，当被结合到医疗装置和/或消费品的涂层的基底中或作为涂层的一部分施加时，可以将抗微生物性能的持续时间延长到医疗装置和/ 或消费品。

80. 发明申请

US20110223254A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM 有权
标题翻译：功能性DIPHENOLICS和可吸收的聚合物
公开(公告)号：US20110223254A1
公开(公告)日：2011-09-15
申请号：US13071623
申请日：2011-03-25
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： A61K9/00 , A61K38/02 , C07C235/34 , C07K5/072 , C07K5/065 , A61K31/715 , A61K31/56 , A61K31/404 , A61P9/00 , C08G63/00 , C08G63/66 , C08G69/48 , A61F2/82
CPC分类号： A61L31/10 , A61L27/18 , A61L27/58 , A61L31/06 , A61L31/148 , C07K5/06078 , C08L67/04
摘要： The present invention relates to dephenolic compounds, an example of which is shown below, which are functionalized, and polymers formed from the same. Polymers formed from the functionalized diphenolics are expected to have controllable degradation profiles, enabling them to release an active component over a desired time range. The polymers are also expected to be useful in a variety of medical applications.
摘要翻译：本发明涉及脱模化合物，其实例如下所示，其被官能化，和由其形成的聚合物。由功能性二元酚形成的聚合物预期具有可控的降解特征，使得它们能够在期望的时间范围内释放活性组分。聚合物也预期在各种医疗应用中是有用的。

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