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71. 发明申请

US20090039734A1 PIEZOELECTRIC MOTOR AND CAMERA DEVICE 有权
标题翻译：压电电机和相机设备
公开(公告)号：US20090039734A1
公开(公告)日：2009-02-12
申请号：US12186882
申请日：2008-08-06
申请人： Hiroshi Takahashi , Takahiro Kokubo , Osamu Nishimura , Toshikatsu Akiba
发明人： Hiroshi Takahashi , Takahiro Kokubo , Osamu Nishimura , Toshikatsu Akiba
IPC分类号： H02N2/04 , H04N5/232
CPC分类号： H04N5/2251 , H02N2/0025 , H02N2/103 , H02N2/108
摘要： A piezoelectric motor includes: a driven member having a substantially spherical shape; a base; a support member provided on the base; a gimbal frame that is provided on a periphery of the driven member; a first bearing that couples the gimbal frame to the support member to be rotatable around a first rotation axis; a second bearing that couples the driven member to the gimbal frame to be rotatable around a second rotation axis that is orthogonal to the first rotation axis; a plurality of piezoelectric elements, each of which has one end fixed onto the base and the other end disposed to be in contact with an actuation portion that abuts the driven member; and an elastic portion that is formed on the gimbal frame, the elastic portion being displaceable in a direction orthogonal to the first rotation axis and the second rotation axis.
摘要翻译：压电马达包括：具有大致球形的从动构件; 一个基地设置在基座上的支撑构件; 设置在被驱动构件的周边上的万向架框架; 第一轴承，其将所述万向架框架联接到所述支撑构件以围绕第一旋转轴线旋转; 第二轴承，其将所述从动构件联接到所述万向架框架，以围绕与所述第一旋转轴线正交的第二旋转轴线旋转; 多个压电元件，每个压电元件的一端固定在基座上，另一端设置成与抵靠从动构件的致动部分接触; 以及形成在所述万向架框架上的弹性部分，所述弹性部分可在与所述第一旋转轴线和所述第二旋转轴线正交的方向上移位。

72. 发明授权

US07352870B2 Active sound muffler and active sound muffling method 失效
标题翻译：主动消声器和主动声音消声法
公开(公告)号：US07352870B2
公开(公告)日：2008-04-01
申请号：US10400564
申请日：2003-03-28
申请人： Akihiko Enamito , Osamu Nishimura , Tsutomu Shioyama
发明人： Akihiko Enamito , Osamu Nishimura , Tsutomu Shioyama
IPC分类号： H03B29/00 , H04B15/00 , F01N1/06
CPC分类号： G10K11/178 , G10K2210/118 , G10K2210/124 , G10K2210/128 , G10K2210/3214 , G10K2210/3224
摘要： An active sound muffler for reducing a sound to be reduced as emitted from a sound source located at one of the opposite sides of a sound insulating wall and diffracted and transmitted to the other side, the muffler comprises a control loudspeaker arranged at the front end or the other side of the sound insulating wall and adapted to output a control sound with a predetermined amplitude and a predetermined phase, a control microphone arranged above the sound insulating wall and adapted to gauge the sound pressure or the acoustic intensity of the sound to be reduced and that of the control sound and a control circuit for controlling the output of the control loudspeaker so as to minimize the sound pressure or the acoustic intensity, whichever appropriate, based on the outcome of gauging of the control microphone, and the control loudspeaker showing a line sound source characteristic.
摘要翻译：一种主动声音消音器，用于减少从位于隔音壁的相对侧中的一个声音处发射并被衍射并传播到另一侧的声源被减小的声音消音器，消声器包括设置在前端的控制扬声器或隔音墙的另一侧，适于输出具有预定振幅和预定相位的控制声音，控制麦克风布置在隔音墙上方，适用于测量声音的声压或声强度。以及用于控制控制扬声器的输出的控制电路的控制电路，以便基于控制麦克风的测量结果，以最小化声压或声强度（以适当的方式），并且控制扬声器显示为线声源特征。

73. 发明授权

US07348324B2 Cyclic amine compounds as CCR5 antagonists 有权
标题翻译：环胺化合物作为CCR5拮抗剂
公开(公告)号：US07348324B2
公开(公告)日：2008-03-25
申请号：US10273111
申请日：2002-10-18
申请人： Shinichi Imamura , Shohei Hashiguchi , Taeko Hattori , Osamu Nishimura , Naoyuki Kanzaki , Masanori Baba , Yoshihiro Sugihara
发明人： Shinichi Imamura , Shohei Hashiguchi , Taeko Hattori , Osamu Nishimura , Naoyuki Kanzaki , Masanori Baba , Yoshihiro Sugihara
IPC分类号： A61P31/18 , A61K31/535 , A61K31/4965 , A61K31/44 , A61K31/47 , C07D413/00 , C07D241/00 , C07D211/00
CPC分类号： C07D401/12 , C07D211/58 , C07D211/62 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/14
摘要： A compound of formula (I) (wherein R1 is a hydrogen atom, a hydrocarbon group which may be substituted, a non-aromatic heterocyclic group which may be substituted, R2 is a hydrocarbon group which may be substituted, a non-aromatic heterocyclic group which may be substituted, or R1 and R2 may combine to each other together with A to form a heterocyclic group which may be substituted; A is N or N+—R5.Y− (R5 is a hydrocarbon group; Y− is a counter anion); R3 is a cyclic hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; n is 0 or 1; R4 is a hydrogen atom, a hydrocarbon group which may be substituted, a heterocyclic group which may be substituted, an alkoxy group which may be substituted, an aryloxy group which may be substituted, or an amino group which may be substituted, E is a divalent aliphatic hydrocarbon group which may be substituted by group(s) other than oxo; G1 is a bond, CO or SO2; G2 is CO, SO2, NHCO, CONH or OCO; J is methine or a nitrogen atom; and each of Q and R is a bond or a divalent C1-3 aliphatic hydrocarbon which may be substituted; provided that J is methine when G2 is OCO, that one of Q and R is not a bond when the other is a bond and that each of Q and R is not substituted by oxo group(s) when G1 is a bond) or a salt thereof has a potent CCR5 antagonistic activity and can be advantageously used for the treatment or prevention of infectious disease of various HIV in human (e.g. AIDS).
摘要翻译：式（I）化合物（其中R 1为氢原子，可被取代的烃基，可被取代的非芳香族杂环基，R 2 O 2 >可以被取代的烃基，可以被取代的非芳族杂环基，或者R 1和R 2可以彼此结合形成A至形成可以被取代的杂环基; A是N或N + - - - - - - - （R 5） SUP>为烃基; Y为 - 抗衡阴离子）; R 3为可被取代的环状烃基或可被取代的杂环基; n 为0或1; R 4为氢原子，可被取代的烃基，可被取代的杂环基，可被取代的烷氧基，可被取代的芳氧基，或可以被取代的氨基，E是可以是二价脂族烃基被除氧基以外的基团取代; G 1是一个键，CO或SO 2; G 2是CO，SO 2，NHCO，CONH或OCO; J为次甲基或氮原子; 并且Q和R中的每一个是可被取代的键或二价C 1-3烷基脂族烃; 条件是当G 2 O是OCO时J为次甲基，当另一个为键并且Q和R各自不被氧代基取代时，Q和R中的一个不为键，当G 1是一个键时）或其盐具有强的CCR5拮抗活性，并且可以有利地用于治疗或预防人类各种HIV感染性疾病（如艾滋病）。

74. 发明申请

US20070112181A1 Method for enrichment/seperation of protein or peptide 审中-公开
标题翻译：蛋白质或肽的富集/分离方法
公开(公告)号：US20070112181A1
公开(公告)日：2007-05-17
申请号：US10582882
申请日：2004-12-21
申请人： Makoto Watanabe , Eiichi Matsuo , Chikako Toda , Osamu Nishimura
发明人： Makoto Watanabe , Eiichi Matsuo , Chikako Toda , Osamu Nishimura
IPC分类号： C07K1/00
CPC分类号： C07K1/24
摘要： The present invention finds a media that can highly selectively retain proteins or peptides to be enriched/separated, as well as provides a method for selectively enriching/separating proteins or peptides using such a media. A method for enrichment/separation of a protein or a peptide, comprising separating a protein or a peptide containing an amino acid residue with a π electron-containing group by using a media with a π electron-containing group. Preferably, the amino acid residue is a tryptophan residue or a tryptophan residue modified with a sulfenyl compound, and the media is a media with phenyl group.
摘要翻译：本发明找到能够高度选择性保留待富集/分离的蛋白质或多肽的培养基，以及提供使用这种培养基选择性富集/分离蛋白质或肽的方法。用于富集/分离蛋白质或肽的方法，包括通过使用具有含π电子的基团的培养基来分离含有氨基酸残基的蛋白质或含有含π电子的基团的肽。优选地，氨基酸残基是用巯基化合物修饰的色氨酸残基或色氨酸残基，并且培养基是具有苯基的培养基。

75. 发明授权

US06525670B1 In-home health care system 失效
标题翻译：家庭保健系统
公开(公告)号：US06525670B1
公开(公告)日：2003-02-25
申请号：US09318017
申请日：1999-05-25
申请人： Kenji Doi , Mitsuhide Maeda , Hitoshi Sakakibara , Masaru Hashimoto , Keiichi Yoshida , Kazuya Kitayama , Masaki Koyama , Osamu Nishimura , Yoshiko Suzuki
发明人： Kenji Doi , Mitsuhide Maeda , Hitoshi Sakakibara , Masaru Hashimoto , Keiichi Yoshida , Kazuya Kitayama , Masaki Koyama , Osamu Nishimura , Yoshiko Suzuki
IPC分类号： G08B2100
CPC分类号： G06F19/3418 , G06F19/00 , G16H10/60 , G16H40/63 , Y10S128/903
摘要： A communication system includes a transmitting device, a receiving device having receiving device for receiving data transmitted by said transmitting device and managing device for managing received data, detecting device for detecting whether or not communication of data between said transmitting device and said receiving device is permitted, said detecting device being provided with at least one of said transmitting device and said receiving device, wherein when said detecting device detects a fact that communication of data is permitted, said transmitting device starts transmitting data to said receiving device.
摘要翻译：通信系统包括发送装置，接收装置，具有接收装置，用于接收由所述发送装置发送的数据和管理接收数据的管理装置，检测装置，检测所述发送装置与所述接收装置之间的数据的通信是否被允许所述检测装置设置有所述发送装置和所述接收装置中的至少一个，其中当所述检测装置检测到允许数据通信的事实时，所述发送装置开始向所述接收装置发送数据。

76. 发明授权

US06309859B1 Method for removing N-terminal methionine 失效
标题翻译：去除N-末端甲硫氨酸的方法
公开(公告)号：US06309859B1
公开(公告)日：2001-10-30
申请号：US09436518
申请日：1999-11-09
申请人： Osamu Nishimura , Masato Suenaga , Hiroaki Ohmae , Shinji Tsuji
发明人： Osamu Nishimura , Masato Suenaga , Hiroaki Ohmae , Shinji Tsuji
IPC分类号： C12P2106
CPC分类号： C07K1/12
摘要： The present invention provides a method for chemically removing a N-terminal methionine residue selectively, specifically and efficiently from a peptide or a salt thereof having an optionally oxidized methinine residue at its N-terminal. The method reacts a peptide or a salt thereof having an optionally oxidized methinine residue at its N-terminal with an &agr;-diketone derivative, followed by hydrolysis.
摘要翻译：本发明提供了一种从其N-末端具有任选氧化的甲硫氨酸残基的肽或其盐选择性地，具体和有效地化学去除N末端甲硫氨酸残基的方法。该方法使其N-末端具有任选氧化的甲硫氨酸残基的肽或其盐与α-二酮衍生物反应，然后水解。

77. 发明授权

US06287806B1 Method for producing a biologically active recombinant cysteine-free peptide 失效
标题翻译：生产生物活性重组半胱氨酸肽的方法
公开(公告)号：US06287806B1
公开(公告)日：2001-09-11
申请号：US09108661
申请日：1998-07-01
申请人： Osamu Nishimura , Masato Kuriyama , Nobuyuki Koyama , Tsunehiko Fukuda
发明人： Osamu Nishimura , Masato Kuriyama , Nobuyuki Koyama , Tsunehiko Fukuda
IPC分类号： C12P2106
CPC分类号： C07K5/0823 , C07K14/503 , C07K14/605 , C07K14/635 , C07K2319/00 , C07K2319/41 , C07K2319/735 , C07K2319/75 , C12N15/62 , C12P21/06
摘要： A cysteine-free peptide is produced by producing a fused protein comprising a protein having cysteine at its N-terminal and a cysteine-free peptide ligated to the N-terminal and subsequently subjecting the fused protein to a reaction for cleaving the peptide linkage.
摘要翻译：通过产生包含其N-末端具有半胱氨酸的蛋白质和与N-末端连接的无半胱氨酸肽并随后使融合蛋白质进行裂解肽键的反应的融合蛋白质来产生半胱氨酸肽。

78. 发明授权

US06268354B1 Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative 失效
标题翻译：用于拮抗含有酰苯胺衍生物的CCR5的药物组合物
公开(公告)号：US06268354B1
公开(公告)日：2001-07-31
申请号：US09661320
申请日：2000-09-13
申请人： Osamu Nishimura , Masanori Baba , Hidekazu Sawada , Naoyuki Kanzaki , Ken-ichi Kuroshima , Mitsuru Shiraishi , Yoshio Aramaki
发明人： Osamu Nishimura , Masanori Baba , Hidekazu Sawada , Naoyuki Kanzaki , Ken-ichi Kuroshima , Mitsuru Shiraishi , Yoshio Aramaki
IPC分类号： A61K31165
CPC分类号： C07D407/12 , A61K31/335 , A61K31/351 , A61K31/452 , A61K31/4523 , A61K31/5377 , A61K31/665 , A61K31/67 , A61K45/06 , C07C233/62 , C07C2602/12 , C07D309/14 , C07D313/08 , C07D337/08
摘要： This invention is to provide a pharmaceutical composition for antagonizing CCR5 which comprises a compound of the formula: wherein R1 is an optionally substituted 5- to 6-membered ring; W is a divalent group of the formula: wherein the ring A is an optionally substituted 5- to 6-membered aromatic ring, X is an optionally substituted C, N or O atom, and the ring B is an optionally substituted 5- to 7-membered ring; Z is a chemical bond or a divalent group; R2 is (1) an optionally substituted amino group in which a nitrogen atom may form a quaternary ammonium, etc., or a salt thereof.
摘要翻译：本发明提供用于拮抗CCR5的药物组合物，其包含下式化合物：其中R 1为任选取代的5至6元环; W是下式的二价基团：其中环A是任选取代的5至6元芳环，X是任选取代的C，N或O原子，并且环B是任选取代的5-至7 记忆环 Z是化学键或二价基团; R2是（1）其中氮原子可以形成季铵等的任选取代的氨基或其盐。

79. 发明授权

US06235771B1 Anilide derivative, production and use thereof 失效
标题翻译：苯胺衍生物，生产和使用
公开(公告)号：US06235771B1
公开(公告)日：2001-05-22
申请号：US09463924
申请日：2000-03-27
申请人： Mitsuru Shiraishi , Masanori Baba , Masaki Seto , Naoyuki Kanzaki , Osamu Nishimura
发明人： Mitsuru Shiraishi , Masanori Baba , Masaki Seto , Naoyuki Kanzaki , Osamu Nishimura
IPC分类号： A61K3138
CPC分类号： C07D335/06 , A61K31/495 , A61K31/52 , A61K31/535 , A61K31/55 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K45/06 , C07D337/08 , C07D409/12 , C07D409/14 , C07F9/655372 , C07F9/65539 , A61K2300/00
摘要： This invention is to provide a compound of the formula: wherein R1 is an optionally substituted 5- to 6-membered ring; the ring A is an optionally substituted 6- to 7-membered ring; the ring B is an optionally substituted benzene ring; n is an integer of 1 or 2; Z is a chemical bond or a divalent group; R2 is (1) an optionally substituted amino group in which a nitrogen atom may form a quaternary ammonium, (2) an optionally substituted nitrogen-containing heterocyclic ring group which may contain a sulfur atom or an oxygen atom as ring constituting atoms and wherein a nitrogen atom may form a quaternary ammonium, (3) a group binding through a sulfur atom or (4) a group of the formula: wherein k is 0 or 1, and when k is 0, a phosphorus atom may form a phosphonium; and R5 and R6 are independently an optionally substituted hydrocarbon group, an optionally substituted hydroxy group or an optionally substituted amino group, and R5 and R6 may bind to each other to form a cyclic group together with the adjacent phosphorus atom, or a salt thereof , which is useful for antagonizing CCR5 and also for the prevention and treatment of infectious disease of HIV.
摘要翻译：本发明提供下式化合物：其中R 1为任选取代的5至6元环; 环A是任选取代的6至7元环; 环B是任选取代的苯环; n为1或2的整数; Z是化学键或二价基团; R2是（1）其中氮原子可以形成季铵的任选取代的氨基，（2）可以含有硫原子或氧原子作为构成原子的环的任选取代的含氮杂环基，其中氮原子可以形成季铵，（3）通过硫原子结合的基团或（4）下式的基团：其中k为0或1，当k为0时，磷原子可以形成鏻; R 5和R 6各自独立地为任选取代的烃基，任选取代的羟基或任选取代的氨基，并且R 5和R 6可以彼此结合形成环状基团以及相邻的磷原子或其盐，其可用于拮抗CCR5以及用于预防和治疗HIV感染性疾病。

80. 发明授权

US5774672A Data transmission system for distributing video and music data 失效
标题翻译：用于分发视频和音乐数据的数据传输系统
公开(公告)号：US5774672A
公开(公告)日：1998-06-30
申请号：US841335
申请日：1997-04-30
申请人： Yasuhiro Funahashi , Kazunori Ikami , Osamu Nishimura , Yuji Kiyohara , Yoshihiko Hibino , Yuichi Yasutomo
发明人： Yasuhiro Funahashi , Kazunori Ikami , Osamu Nishimura , Yuji Kiyohara , Yoshihiko Hibino , Yuichi Yasutomo
IPC分类号： G10K15/04 , G10H1/36 , G10K15/02 , H04H20/78 , H04H60/37 , H04H60/43 , H04H60/65 , H04N7/10 , H04N7/16 , H04N7/173 , H04N21/262 , H04L5/00
CPC分类号： H04N7/10 , G10H1/365 , H04H20/106 , H04H20/16 , H04H20/33 , H04H20/42 , H04H20/79 , H04H60/65 , H04N7/173 , G10H2220/011 , G10H2240/125 , G10H2240/241 , G10H2240/265 , H04H20/78 , H04H60/37 , H04H60/43
摘要： In the karaoke system 1, a center 3 is connected to a plurality of karaoke terminals 5 by a coaxial cable 7. The center 3 divides the karaoke song data stored in the memory device 13 over several channels and transmits all the karaoke song data within a fixed time period in succession to the karaoke terminals 5 via the coaxial cable 7. This operation is performed regardless of whether or not a song is requested from one of the karaoke terminals 5. Whether the karaoke data transmitted in succession is data of a requested song is determined by the control portion 41 of a karaoke terminal 5. If so, karaoke performance processes are performed wherein the karaoke data is reproduced and the orchestral accompaniment and lyric image is outputted.
摘要翻译：在卡拉OK系统1中，中心3通过同轴电缆7连接到多个卡拉OK终端5.中心3通过多个通道划分存储在存储装置13中的卡拉OK歌曲数据，并将所有卡拉OK歌曲数据发送到一个经由同轴电缆7连续到卡拉OK终端5的固定时间段。无论是否从卡拉OK终端5中的一个请求歌曲，都执行该操作。连续发送的卡拉OK数据是否是所请求歌曲的数据由卡拉OK终端5的控制部分41确定。如果是，则执行卡拉OK演奏处理，其中再现卡拉OK数据，并输出管弦伴奏和歌词图像。

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