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71. 发明授权

US08670814B2 Low-noise optical probes for reducing ambient noise 失效
标题翻译：用于降低环境噪声的低噪声光学探头
公开(公告)号：US08670814B2
公开(公告)日：2014-03-11
申请号：US12360828
申请日：2009-01-27
申请人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , David R. Tobler , Thomas J. Gerhardt , Eugene E. Mason , Mike A. Mills
发明人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , David R. Tobler , Thomas J. Gerhardt , Eugene E. Mason , Mike A. Mills
IPC分类号： A61B5/1455
CPC分类号： A61B5/14552 , A61B5/02427 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B2562/08 , A61B2562/12 , H05K1/189
摘要： An optical probe, which is particularly suited to reduce noise in measurements taken on an easily compressible material, such as a finger, a toe, a forehead, an earlobe, or a lip, measures characteristics of the material. A neonatal and adult disposable embodiment of the probe include adhesive coated surfaces to securely affix the probe onto the patient. In addition, the surface of the probe is specially constructed to reduce the effect of ambient noise.
摘要翻译：光学探头特别适用于减少在容易压缩的材料（例如手指，脚趾，额头，耳垂或唇部）上进行的测量中的噪音，测量材料的特性。探针的新生儿和成人一次性实施例包括粘合剂涂覆的表面以牢固地将探针附接到患者身上。此外，探头的表面是特别构造的，以减少环境噪声的影响。

72. 发明申请

US20080036752A1 SIGNAL PROCESSING APPARATUS AND METHOD 有权
标题翻译：信号处理装置和方法
公开(公告)号：US20080036752A1
公开(公告)日：2008-02-14
申请号：US11842128
申请日：2007-08-20
申请人： Mohamed Diab , Rex McCarthy
发明人： Mohamed Diab , Rex McCarthy
IPC分类号： G09G5/00
CPC分类号： A61B5/7257 , A61B5/0205 , A61B5/02416 , A61B5/02433 , A61B5/1455 , A61B5/14551 , A61B5/14552 , A61B5/6826 , A61B5/7203 , A61B5/7214 , A61B5/7225 , A61B5/726 , A61B5/7278 , A61B5/742 , G06K9/0051
摘要： A method and an apparatus to analyze two measured signals that are modeled as containing desired and undesired portions such as noise, FM and AM modulation. Coefficients relate the two signals according to a model defined in accordance with the present invention. In one embodiment, a transformation is used to evaluate a ratio of the two measured signals in order to find appropriate coefficients. The measured signals are then fed into a signal scrubber which uses the coefficients to remove the unwanted portions. The signal scrubbing is performed in either the time domain or in the frequency domain. The method and apparatus are particularly advantageous to blood oximetry and pulserate measurements. In another embodiment, an estimate of the pulserate is obtained by applying a set of rules to a spectral transform of the scrubbed signal. In another embodiment, an estimate of the pulserate is obtained by transforming the scrubbed signal from a first spectral domain into a second spectral domain. The pulserate is found by identifying the largest spectral peak in the second spectral domain.
摘要翻译：一种用于分析被建模为包含期望和不期望的部分（例如噪声，FM和AM调制）的两个测量信号的方法和装置。系数根据根据本发明定义的模型关联两个信号。在一个实施例中，使用变换来评估两个测量信号的比率以找到适当的系数。然后将测量的信号馈送到信号洗涤器中，该信号洗涤器使用系数去除不需要的部分。信号擦除在时域或频域中进行。该方法和装置对于血氧饱和度测量和脉动测量是特别有利的。在另一个实施例中，通过将一组规则应用于经擦除的信号的频谱变换来获得脉冲发生器的估计。在另一个实施例中，通过将擦除的信号从第一光谱域变换成第二光谱域来获得脉冲发生器的估计。通过识别第二个光谱域中最大的光谱峰值来发现脉冲发生器。

73. 发明申请

US20070225581A1 SIGNAL PROCESSING APPARATUS 有权
标题翻译：信号处理装置
公开(公告)号：US20070225581A1
公开(公告)日：2007-09-27
申请号：US11754238
申请日：2007-05-25
申请人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , Ibrahim Elfadel , Rex McCarthy , Walter Weber , Robert Smith
发明人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , Ibrahim Elfadel , Rex McCarthy , Walter Weber , Robert Smith
IPC分类号： A61B5/145 , G06F17/00
CPC分类号： A61B5/14551 , A61B5/021 , A61B5/02154 , A61B5/024 , A61B5/029 , A61B5/0402 , A61B5/0476 , A61B5/0816 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/4821 , A61B5/7203 , A61B5/7207 , A61B5/7214 , A61B5/7225 , A61B5/7239 , A61B5/7253 , A61B5/7257 , A61B5/726 , A61B6/00 , A61B8/00 , A61B8/5276 , G01N2021/3144 , G06K9/0051 , H04B1/123
摘要： The present invention involves a method and an apparatus for analyzing measured signals, including the determination of a measurement of correlation in the measured signals during a calculation of a physiological parameter of a monitored patient. Use of this invention is described in particular detail with respect to blood oximetry measurements.
摘要翻译：本发明涉及一种用于分析测量信号的方法和装置，包括在计算被监测患者的生理参数期间确定测量信号中的相关性的测量。关于血液测碘法测量，特别详细地描述了本发明的用途。

74. 发明申请

US20070112260A1 Manual and automatic probe calibration 失效
标题翻译：手动和自动探头校准
公开(公告)号：US20070112260A1
公开(公告)日：2007-05-17
申请号：US11640077
申请日：2006-12-15
申请人： Mohamed Diab , Massi Kiani , Charles Ragsdale , James Lepper
发明人： Mohamed Diab , Massi Kiani , Charles Ragsdale , James Lepper
IPC分类号： A61B5/00
CPC分类号： A61B5/1495 , A61B5/0205 , A61B5/02427 , A61B5/14552 , A61B5/6826 , A61B5/6838 , A61B2562/08 , G01J3/02 , G01J3/0254 , G01J3/027 , G01J3/0275 , G01J3/0291 , G01J3/10 , G01J2003/2866 , G01N21/255 , G01N21/274 , G01N21/31 , G01N21/3151 , G01N21/39 , G01N2021/3144 , G01N2201/0627
摘要： Embodiments of the present disclosure include an optical probe capable of communicating identification information to a patient monitor in addition to signals indicative of intensities of light after attenuation by body tissue. The identification information may indicate operating wavelengths of light sources, indicate a type of probe, such as, for example, that the probe is an adult probe, a pediatric probe, a neonatal probe, a disposable probe, a reusable probe, or the like. The information could also be utilized for security purposes, such as, for example, to ensure that the probe is configured properly for the oximeter, to indicate that the probe is from an authorized supplier, or the like. In one preferred embodiment, coding resistors could be provided across the light sources to allow additional information about the probe to be coded without added leads. However, any device could be used without it being used in parallel.
摘要翻译：本公开的实施例还包括能够向身体组织衰减之后除了表示光强度的信号之外，向患者监视器传送识别信息的光学探针。识别信息可以指示光源的操作波长，指示探针的类型，例如探针是成人探针，儿科探针，新生儿探针，一次性探针，可重复使用的探针等。该信息也可以用于安全目的，例如，以确保探针被适当地配置用于血氧计，以指示探针来自授权供应商等。在一个优选实施例中，编码电阻器可以跨越光源提供，以允许关于探针的附加信息被编码而没有添加引线。但是，任何设备都可以在没有并行使用的情况下使用。

75. 发明申请

US20060217609A1 Signal processing apparatus 失效
公开(公告)号：US20060217609A1
公开(公告)日：2006-09-28
申请号：US11432278
申请日：2006-05-11
申请人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , Ibrahim Elfadel , Rex McCarthy , Walter Weber , Robert Smith
发明人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , Ibrahim Elfadel , Rex McCarthy , Walter Weber , Robert Smith
IPC分类号： A61B5/00
CPC分类号： A61B5/14551 , A61B5/021 , A61B5/02154 , A61B5/024 , A61B5/029 , A61B5/0402 , A61B5/0476 , A61B5/0816 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/4821 , A61B5/7203 , A61B5/7207 , A61B5/7214 , A61B5/7225 , A61B5/7239 , A61B5/7253 , A61B5/7257 , A61B5/726 , A61B6/00 , A61B8/00 , A61B8/5276 , G01N2021/3144 , G06K9/0051 , H04B1/123
摘要： The present invention involves a method and an apparatus for analyzing measured signals, including the determination of a measurement of correlation in the measured signals during a calculation of a physiological parameter of a monitored patient. Use of this invention is described in particular detail with respect to blood oximetry measurements.

76. 发明申请

US20060206021A1 Plethysmograph pulse recognition processor 有权
标题翻译：体积描记脉冲识别处理器
公开(公告)号：US20060206021A1
公开(公告)日：2006-09-14
申请号：US11418328
申请日：2006-05-03
申请人： Mohamed Diab
发明人： Mohamed Diab
IPC分类号： A61B5/00 , A61B5/02
CPC分类号： A61B5/14551 , A61B5/02416 , A61B5/7264
摘要： A time domain rule-based processor provides recognition of individual pulses in a pulse oximeter-derived waveform.
摘要翻译：基于时域规则的处理器提供了脉冲血氧计衍生波形中各个脉冲的识别。

77. 发明申请

US20050065417A1 Dual-mode pulse oximeter 有权
标题翻译：双模脉搏血氧仪
公开(公告)号：US20050065417A1
公开(公告)日：2005-03-24
申请号：US10911391
申请日：2004-08-03
申请人： Ammar Ali , Don Carothers , David Dalke , Mohamed Diab , Julian Goldman , Massi Kiani , Michael Lee , Jerome Novak , Robert Smith , Val Vaden
发明人： Ammar Ali , Don Carothers , David Dalke , Mohamed Diab , Julian Goldman , Massi Kiani , Michael Lee , Jerome Novak , Robert Smith , Val Vaden
IPC分类号： A61B5/00
CPC分类号： A61B5/14551 , A61B5/0002 , A61B5/1495 , A61B5/742 , A61B2560/0271 , A61B2560/0456 , A61B2562/085 , G06F19/00
摘要： A pulse oximeter has an integrated mode in which it operates as a plug-in module for a multiparameter patient monitoring system (MPMS). The pulse oximeter also has a portable mode in which operates separately from the MPMS as a battery-powered handheld or standalone instrument. The pulse oximeter has a sensor port that receives a photo-plethysmographic signal as input to an internal processor. The pulse oximeter processes this sensor signal to derive oxygen saturation and pulse rate measurements. In the portable mode, this information is provided on its display, and stored in memory for trend capability. In the integrated mode, the pulse oximeter provides oxygen saturation and pulse rate measurements to the MPMS through a docking station to be displayed on a MPMS monitor. In the integrated mode, the portable pulse oximeter docks to the docking station, which in turn is inserted in one or more MPMS slots. The docking station can function as a simple electrical pass-through device between the docked portable pulse oximeter and the MPMS or it can provide a MPMS communications interface.
摘要翻译：脉搏血氧计具有集成模式，其作为用于多参数病人监测系统（MPMS）的插件模块。脉搏血氧计还具有便携式模式，其中与MPMS分开操作，作为电池供电的手持或独立仪器。脉搏血氧计具有传感器端口，其接收作为对内部处理器的输入的光学体积描记信号。脉冲血氧计处理该传感器信号以导出氧饱和度和脉搏率测量。在便携式模式中，该信息在其显示器上提供，并存储在存储器中用于趋势能力。在集成模式中，脉搏血氧计通过对接站向MPMS提供氧饱和度和脉搏率测量，以在MPMS监视器上显示。在集成模式中，便携式脉搏血氧仪停靠在对接站，对接站又插入一个或多个MPMS槽中。对接站可以作为对接便携式脉搏血氧计与MPMS之间的简单电气穿越装置，或者可以提供MPMS通信接口。

78. 发明申请

US20050043600A1 Low-noise optical probes for reducing ambient noise 失效
标题翻译：用于降低环境噪声的低噪声光学探头
公开(公告)号：US20050043600A1
公开(公告)日：2005-02-24
申请号：US10957843
申请日：2004-10-04
申请人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , David Tobler , Thomas Gerhardt , Eugene Mason , Mike Mills
发明人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , David Tobler , Thomas Gerhardt , Eugene Mason , Mike Mills
IPC分类号： A61B5/022 , A61B5/00 , A61B5/024 , A61B5/0245 , A61B5/145 , A61B5/1455 , G01N21/17 , G01N21/59 , H05K1/18
CPC分类号： A61B5/14552 , A61B5/02427 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B2562/08 , A61B2562/12 , H05K1/189
摘要： An optical probe, which is particularly suited to reduce noise in measurements taken on an easily compressible material, such as a finger, a toe, a forehead, an earlobe, or a lip, measures characteristics of the material. A neonatal and adult disposable embodiment of the probe include adhesive coated surfaces to securely affix the probe onto the patient. In addition, the surface of the probe is specially constructed to reduce the effect of ambient noise.
摘要翻译：光学探头特别适用于减少在容易压缩的材料（例如手指，脚趾，额头，耳垂或唇部）上进行的测量中的噪音，测量材料的特性。探针的新生儿和成人一次性实施例包括粘合剂涂覆的表面以牢固地将探针附接到患者身上。此外，探头的表面是特别构造的，以减少环境噪声的影响。

79. 发明申请

US20050020893A1 Optical spectroscopy pathlength measurement system 有权
标题翻译：光谱光程测量系统
公开(公告)号：US20050020893A1
公开(公告)日：2005-01-27
申请号：US10695405
申请日：2003-10-28
申请人： Mohamed Diab
发明人： Mohamed Diab
IPC分类号： A61B5/00 , G01N21/21 , G01N21/49
CPC分类号： A61B5/6826 , A61B5/14558 , A61B5/6838 , G01N21/21 , G01N21/49
摘要： A physiological monitor utilizes Faraday rotation measurements to estimate mean photon pathlengths through tissue. These pathlength estimates, along with corresponding optical spectroscopy measurements allow the noninvasive monitoring of blood constituent concentrations. The technique is particularly applicable to noninvasive blood glucose measurements. The physiological monitor has a polarized light source for illuminating tissue and a magnetic field generator which creates a magnetic field within the tissue during illumination. The magnetic field imparts a Faraday rotation in the plane of polarization of the incident light beam as it propagates through the tissue and emerges as a transmitted light beam. A polarimeter is used to measure the rotation of the transmitted light. A signal processor then computes an estimate of the mean pathlength from the polarimeter output. The polarized light source has a multiple wavelength optical emitter and, in conjunction with the polarimeter detector, also functions as a spectrometer. The signal processor combines spectroscopic measurements at various wavelengths with corresponding mean pathlength estimates to compute blood constituent concentrations.
摘要翻译：生理监测器利用法拉第旋转测量来估计通过组织的平均光子路径长度。这些光程长度估计以及相应的光学光谱测量可以对血液成分浓度进行非侵入性监测。该技术特别适用于无创血糖测量。生理监视器具有用于照射组织的偏振光源和在照明期间在组织内产生磁场的磁场发生器。当入射光束传播通过组织时，磁场在入射光束的偏振平面中施加法拉第旋转，并作为透射光束出射。使用偏光计来测量透射光的旋转。然后，信号处理器从偏振计输出计算平均路径长度的估计。偏振光源具有多波长光发射器，并且与偏振仪检测器一起也用作光谱仪。信号处理器将各种波长的光谱测量结合相应的平均光程长度估计来计算血液成分浓度。

80. 发明申请

US20090143657A1 LOW-NOISE OPTICAL PROBES FOR REDUCING AMBIENT NOISE 失效
标题翻译：低噪声光学探头，用于减少环境噪声
公开(公告)号：US20090143657A1
公开(公告)日：2009-06-04
申请号：US12360828
申请日：2009-01-27
申请人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , David R. Tobler , Thomas J. Gerhardt , Eugene E. Mason , Mike A. Mills
发明人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , David R. Tobler , Thomas J. Gerhardt , Eugene E. Mason , Mike A. Mills
IPC分类号： A61B5/1455
CPC分类号： A61B5/14552 , A61B5/02427 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B2562/08 , A61B2562/12 , H05K1/189
摘要： An optical probe, which is particularly suited to reduce noise in measurements taken on an easily compressible material, such as a finger, a toe, a forehead, an earlobe, or a lip, measures characteristics of the material. A neonatal and adult disposable embodiment of the probe include adhesive coated surfaces to securely affix the probe onto the patient. In addition, the surface of the probe is specially constructed to reduce the effect of ambient noise.
摘要翻译：光学探头特别适用于减少在容易压缩的材料（例如手指，脚趾，额头，耳垂或唇部）上进行的测量中的噪音，测量材料的特性。探针的新生儿和成人一次性实施例包括粘合剂涂覆的表面以牢固地将探针附接到患者身上。此外，探头的表面是特别构造的，以减少环境噪声的影响。

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