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71. 发明授权

US06875184B2 Method and apparatus for noninvasive intraductal fluid diagnostic screen 有权
标题翻译：无创性导管内液体诊断屏的方法和装置
公开(公告)号：US06875184B2
公开(公告)日：2005-04-05
申请号：US10072538
申请日：2002-02-08
申请人： Kevin B. Morton , Rex O. Bare , Jeffrey C. Smith , Timothy J. Payne , Paul Gleason
发明人： Kevin B. Morton , Rex O. Bare , Jeffrey C. Smith , Timothy J. Payne , Paul Gleason
IPC分类号： A61B10/00 , A61B10/02 , A61M1/06 , A61B5/00 , B65D81/00
CPC分类号： A61B5/6834 , A61B10/0041 , A61B10/0045 , A61B10/0283 , A61M1/06 , A61M1/064 , A61M1/066 , A61M2205/3653
摘要： Disclosed is a method and apparatus for accomplishing a noninvasive screen for breast disease markers, including breast cancer markers and cytologically abnormal cells. Intraductal fluid is noninvasively aspirated using compression, heating and suction cycles. The removed sample is thereafter assayed for the presence of cytologically abnormal cells and/or one or more breast disease markers. In addition to the diagnostic applications of the disclosed method and apparatus, a therapeutic application is also contemplated wherein intraductal fluids are noninvasively aspirated using compression, heating and suction cycles to remove toxic buildups within the fluid.
摘要翻译：公开了一种用于完成乳腺疾病标志物（包括乳腺癌标志物和细胞学异常细胞）的非侵入性筛查的方法和装置。使用压缩，加热和抽吸循环非导管式吸入导管内液体。然后检测去除的样品是否存在细胞学异常细胞和/或一种或多种乳腺疾病标记物。除了所公开的方法和装置的诊断应用之外，还考虑了治疗应用，其中使用压缩，加热和抽吸循环非侵入式吸入导管内流体以去除流体内的毒性积聚。

72. 发明授权

US5806515A Supplemental oxygen adapter for tracheostomy speaking valves 失效
标题翻译：用于气管切开术的补充氧气适配器
公开(公告)号：US5806515A
公开(公告)日：1998-09-15
申请号：US828429
申请日：1997-03-28
申请人： Rex O. Bare , Andrew J. Scherer
发明人： Rex O. Bare , Andrew J. Scherer
IPC分类号： A61F2/20 , A61M16/04 , A61M16/10 , A61M16/00
CPC分类号： A61F2/203 , A61M16/0463 , A61M16/0468 , A61M16/10
摘要： An oxygen adapter for delivering low volume supplemental oxygen to a tracheostomized patient using a conventional tracheostomy speaking valve is provided, the adapter including a tube fitting for receiving conventional tubing thereon, and an outlet section attached to the tube fitting and defining a channel communicating between the tube fitting and an outlet end of the outlet section. The outlet section preferably extends axially from the tube fitting along the outer wall of a speaking valve to which the adapter is connected, the outlet end being located adjacent an inlet of the speaking valve, thereby delivering oxygen from the tubing received on the tube fitting to the inlet of the speaking valve. The adapter may be detachably connectable to the cylindrical wall of the speaking valve, preferably by a pair of semi-rigid gripping flanges adapted to peripherally engage the cylindrical wall of the speaking valve. The adapter preferably comprises injection-molded plastic, such as polycarbonate.
摘要翻译：提供了一种氧传感器，用于使用传统的气管切开口语阀向气管造影患者输送低体积的补充氧气，适配器包括用于接收其上常规管道的管接头和连接到管接头的出口部分，并且限定通道管接头和出口部分的出口端。出口部分优选地从管接头沿着适配器连接的说话阀的外壁轴向延伸，出口端邻近说话阀的入口定位，从而将从管接头上接收的管道输送氧气说话阀的入口。适配器可以可拆卸地连接到说话阀的圆柱形壁，优选地通过一对半刚性的夹紧凸缘，其适合于周向接合说话阀的圆柱形壁。适配器优选地包括注射成型的塑料，例如聚碳酸酯。

73. 发明授权

US5577995A Spinal and soft tissue mobilizer 失效
标题翻译：脊髓和软组织移动
公开(公告)号：US5577995A
公开(公告)日：1996-11-26
申请号：US77323
申请日：1993-06-14
申请人： Grace L. Walker , Rex O. Bare
发明人： Grace L. Walker , Rex O. Bare
IPC分类号： A61H15/00
CPC分类号： A61H15/0092 , A61H2015/0007 , A61H2015/005 , A61H2201/1253 , A61H2201/1284 , A61H2201/1623 , A61H2201/1669 , A61H2201/1695 , A61H2203/0406 , A61H2203/0456 , A61H2205/081
摘要： A therapeutic device to mobilize the spinal joints and soft tissues surrounding the human spine. The device includes two substantially solid spherical balls mounted on a shaft for independent rotation. In one embodiment, the balls have a spherical to elliptical configuration and comprise an inner ball portion of a variable density synthetic plastic material and with an outer covering or portion comprised of a flexible material. The balls have a confronting area forming a substantially elliptical shape extending from a major spherical ball portion. Another embodiment comprises two spherical rubber balls having an inner ball formed of hard material to assist in the mobilizing operation and an outer flexible rubber cover. In either embodiment, the balls may be mounted on the shaft via suitable sleeves disposed through the inner ball portions. The device may be used in self-treatment or may be applied by another person.
摘要翻译：一种用于动员脊柱关节和围绕人类脊柱的软组织的治疗装置。该装置包括安装在轴上用于独立旋转的两个基本上实心的球形球。在一个实施例中，球具有球形至椭圆形构造，并且包括可变密度合成塑料材料的内球部分以及由柔性材料构成的外覆盖物或部分。球具有形成从主球形部分延伸的基本上椭圆形的面对区域。另一个实施例包括两个球形橡胶球，其具有由硬质材料形成的内球以协助动员操作和外部柔性橡胶盖。在任一实施例中，球可以通过穿过内球部分设置的合适的套筒安装在轴上。该装置可以用于自我治疗或者可以被另一个人使用。

74. 发明授权

US5054480A Personal air filtration and control system 失效
标题翻译：个人空气过滤和控制系统
公开(公告)号：US5054480A
公开(公告)日：1991-10-08
申请号：US537700
申请日：1990-06-14
申请人： Rex O. Bare , David R. Millar , Harry N. Herbert
发明人： Rex O. Bare , David R. Millar , Harry N. Herbert
IPC分类号： A41D13/00 , A41D13/11 , A61G10/00 , A62B18/04
CPC分类号： A62B18/045 , A41D13/11 , A42B3/286
摘要： An air flow and filtration control system in the form of a headgear which is worn by a physician during a surgical procedure, a technician during an assembly process, or any other user wherein a controlled air flow and air filtration is required or desired. The flow through system includes a relatively rigid, open frame, skeleton headgear structure which substantially surrounds the head of the wearer. The structure includes ductwork and is adjustably attached to a headband formed of straps which are adapted to snugly engage the head of the wearer.A plurality of fans or other air moving devices are mounted in the structure. The fans are positioned to move air through the integral ducts in the structure. A shroud (or hood) is draped over and attached to the structure in such a fashion as to completely cover the structure and to cover at least a portion of the wearer in order to maintain sterile or controlled conditions. A relatively planar transparent screen or "window" is provided at the front of the apparatus for substantially undistorted viewing. Typically, the transparent screen is mounted in the shroud and is removable therewith. Filtration devices are formed or mounted in the shroud so as to be disposed adjacent to the fans when the shroud is placed over the structure. A suitable power supply, such as a battery pack or the like, is used to selectively power the fans. It is anticipated that at least the shroud (and the components mounted thereto) will be disposable.

75. 发明授权

US4522211A Medical electrode construction 失效
标题翻译：医用电极结构
公开(公告)号：US4522211A
公开(公告)日：1985-06-11
申请号：US310118
申请日：1981-10-09
申请人： Rex O. Bare , Earl F. Robinson
发明人： Rex O. Bare , Earl F. Robinson
IPC分类号： A61B5/0408 , A61B5/04
CPC分类号： A61B5/04087 , A61B2562/125
摘要： There is disclosed an electrode construction of the type including a terminal arrangement and support structure for said terminal arrangement, said support structure adapted for the transcutaneous application of the electrode to a patient. The support structure may be fabricated from a layer of foam or microporous material, or plural layer employing a combination of both, or from a layer of conductive adhesive. The terminal arrangement may be of single terminal or multi-terminal design, and is provided by a conductive pattern printed on a semi-flexible plastic-like sheet, wherein said pattern is printed with a conductive ink of the type employing a conductive metal, such as silver, in a binder composition. The disclosure also contemplates novel structure for connection of the electrode to a lead wire, as well as several novel, overall designs for the construction of the electrode support means.
摘要翻译：公开了一种类型的电极结构，其包括用于所述端子装置的端子装置和支撑结构，所述支撑结构适于经由电极施加到患者身上。支撑结构可以由泡沫或微孔材料层或采用两者的组合的多层或由导电粘合剂层制成。端子布置可以是单端子或多端子设计，并且由印刷在半柔性塑料片上的导电图案提供，其中所述图案印刷有使用导电金属的导电油墨，例如作为银，在粘合剂组合物中。本公开还考虑了用于将电极连接到引线的新颖结构，以及用于构造电极支撑装置的几种新颖的整体设计。

76. 发明授权

US4126126A Non-metallic pregelled electrode 失效
标题翻译：非金属预胶电极
公开(公告)号：US4126126A
公开(公告)日：1978-11-21
申请号：US709140
申请日：1976-07-27
申请人： Rex O. Bare , Earl F. Robinson , Kevin R. Smith
发明人： Rex O. Bare , Earl F. Robinson , Kevin R. Smith
IPC分类号： A61B5/0408 , A61B5/04
CPC分类号： A61B5/0408 , Y10S439/909
摘要： An electrode pad, an electrical lead wire connector, and an electrode system composed of the pad and connector which exhibits a DC offset of about 1mV, an AC impedance of less than 100.OMEGA., and a stable rectification of less than 0.2mV.The electrode pad of the system, for attachment to the skin for detecting biological or physiological electrical potentials, includes an electrically non-conductive disc, an electrolyte saturated porous matrix in the disc and integral provision for attaching an electrical connector, the pad having no metal components.The electrical connector has an electrically conductive probe at one end composed of a non-conductive plastic with a conductive silver and silver chloride coating thereover.
摘要翻译：电极焊盘，电引线连接器以及由焊盘和连接器组成的电极系统，其表现出约1mV的DC偏移，小于100欧姆的AC阻抗，以及小于0.2mV的稳定整流。

77. 发明授权

US09194877B2 Systems for bioagent indentification 有权
标题翻译：生物识别系统
公开(公告)号：US09194877B2
公开(公告)日：2015-11-24
申请号：US12837191
申请日：2010-07-15
申请人： Steven A. Hofstadler , Jose R. Gutierrez , James C. Hannis , Jared J. Drader , Rex O. Bare , Jeffrey C. Smith , Paul J. Gleason , Jared Nathanson , Ronald K. Bergold , Robert D. Miller , Kevin S. Oberkramer
发明人： Steven A. Hofstadler , Jose R. Gutierrez , James C. Hannis , Jared J. Drader , Rex O. Bare , Jeffrey C. Smith , Paul J. Gleason , Jared Nathanson , Ronald K. Bergold , Robert D. Miller , Kevin S. Oberkramer
IPC分类号： C12M1/34 , C12M3/00 , G01N35/00 , B01L7/00
CPC分类号： C12Q1/686 , B01L7/52 , C12Q1/6806 , G01N27/72 , G01N35/00871 , G01N35/0092 , G01N35/0095 , G01N35/0098 , G01N35/025 , G01N35/026 , G01N2035/00534
摘要： The present invention provides systems and methods for analysis of samples, particularly biological and environmental sample to detect biomolecules of interest contained therein. A variety of system components are described herein, including, but not limited to, components for sample handling, mixing of materials, sample processing, transfer of materials, and analysis of materials. The invention further provides mechanisms for combining and integrating the different components and for housing, moving, and storing system components or the system as a whole. The systems may include any one or more or all of these components. The system finds particular use when employed for analysis of nucleic acid molecule using mass spectrometry, however, the invention is not limited such specific uses.
摘要翻译：本发明提供用于分析样品，特别是生物和环境样品以检测其中所含感兴趣的生物分子的系统和方法。本文描述了各种系统组件，包括但不限于用于样品处理，材料混合，样品处理，材料转移和材料分析的组件。本发明还提供了用于组合和集成不同部件并且用于整体地容纳，移动和存储系统部件或系统的机构。这些系统可以包括这些组件中的任何一个或多个或全部。当使用质谱法分析核酸分子时，该系统特别有用，但本发明不限于此。

78. 发明授权

US08950604B2 Lift and mount apparatus 有权
标题翻译：提升和安装设备
公开(公告)号：US08950604B2
公开(公告)日：2015-02-10
申请号：US12837245
申请日：2010-07-15
申请人： Jared J. Drader , Steven A. Hofstadler , Jose R. Gutierrez , Paul J. Gleason , Andrew J. Scherer , Rex O. Bare
发明人： Jared J. Drader , Steven A. Hofstadler , Jose R. Gutierrez , Paul J. Gleason , Andrew J. Scherer , Rex O. Bare
IPC分类号： B66C19/00 , B66C5/04 , B01L9/02 , B01L9/00
CPC分类号： B66C5/04 , B01L9/00 , B01L9/02
摘要： The present invention provides devices, apparatuses, and systems for lifting and mounting of clinical- and research-related equipment. In particular, the present invention provides a lift and mount system for mass spectrometers (e.g., for time of flight (TOF) mass spectrometers (MS)).
摘要翻译：本发明提供用于提升和安装临床和研究相关设备的装置，装置和系统。特别地，本发明提供用于质谱仪的提升和安装系统（例如，对于飞行时间（TOF）质谱仪（MS））。

79. 发明授权

US08609430B2 Sample processing units, systems, and related methods 失效
公开(公告)号：US08609430B2
公开(公告)日：2013-12-17
申请号：US13595189
申请日：2012-08-27
申请人： Steven A. Hofstadler , Jared J. Drader , Jose R. Gutierrez , Paul J. Gleason , Rex O. Bare , Robert D. Miller , Jeffrey C. Smith
发明人： Steven A. Hofstadler , Jared J. Drader , Jose R. Gutierrez , Paul J. Gleason , Rex O. Bare , Robert D. Miller , Jeffrey C. Smith
IPC分类号： G01N9/00 , G01N33/00
CPC分类号： G01N1/10 , G01N1/02 , G01N35/0098 , G01N35/025 , G01N2035/00524
摘要： Sample processing units useful for mixing and purifying materials, such as fluidic materials are provided. A sample processing unit typically includes a container configured to contain a sample comprising magnetically responsive particles, and one or more magnets that are in substantially fixed positions relative to the container. A sample processing unit also generally includes a conveyance mechanism configured to convey the container to and from a position that is within magnetic communication with the magnet, e.g., such that magnetically responsive particles with captured analytes can be retained within the container when other materials are added to and/or removed from the container. Further, a sample processing unit also typically includes a rotational mechanism that is configured to rotate the container, e.g., to effect mixing of sample materials disposed within the container. Related carrier mechanisms, sample processing stations, systems, and methods are also provided.

80. 发明申请

US20130296996A1 Transdermal Medical Patch 有权
标题翻译：透皮医疗贴片
公开(公告)号：US20130296996A1
公开(公告)日：2013-11-07
申请号：US13464634
申请日：2012-05-04
申请人： Stephen Wahlgren , Martin J. Nohilly , Anthony R. DiUbaldi , Rex O. Bare , Bradley Sargent , Michael W. Ammerman , Jeffrey C. Smith , Kathryn M. Kukulka
发明人： Stephen Wahlgren , Martin J. Nohilly , Anthony R. DiUbaldi , Rex O. Bare , Bradley Sargent , Michael W. Ammerman , Jeffrey C. Smith , Kathryn M. Kukulka
IPC分类号： A61N1/04
CPC分类号： A61N1/303 , A61N1/0428 , A61N1/0456 , A61N1/0492 , A61N1/36014
摘要： A medical patch having a multi-piece bottom liner including a central liner sequentially removable independently of two outer perimeter liners. The multi-piece liner covering two adhesives of different peel force. Removal of the central liner exposes a first temporary/repositionable adhesive. Once properly positioned, the outer perimeter liners are removed to expose a second stronger adhesive. A foam cushioning layer is disposed beneath and extends beyond a footprint of every printed circuit board to prevent skin irritation. The medical patch may be designed specifically for stimulation of the sacral (S3 foramen) spinal nerve without the use of a separate mechanical placement tool or assistance by another.
摘要翻译：一种具有多片底部衬垫的医疗贴片，其包括独立于两个外周边衬垫顺序地移除的中心衬垫。多片衬里覆盖两种不同剥离力的粘合剂。去除中心衬垫露出第一个临时/可重新定位的粘合剂。一旦正确定位，移除外周衬里以露出第二较强的粘合剂。泡沫缓冲层设置在每个印刷电路板的下方并延伸超过每个印刷电路板的印迹，以防止皮肤刺激。医疗补片可以专门设计用于刺激骶骨（S3孔）脊神经，而不使用单独的机械放置工具或由另一机械辅助。

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