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71. 发明申请

US20110282368A1 Fistula Repair Device with Extendable Barbs and Therapeutic Cell Delivery 审中-公开
标题翻译：瘘修补装置与可扩展的倒钩和治疗细胞递送
公开(公告)号：US20110282368A1
公开(公告)日：2011-11-17
申请号：US12778587
申请日：2010-05-12
申请人： Jeffrey S. Swayze , Foster B. Stulen , Mark H. Ransick , Steven G. Hall , John A. Hibner , Julia J. Hwang , Yolanda F. Carter , Frederick E. Shelton, IV
发明人： Jeffrey S. Swayze , Foster B. Stulen , Mark H. Ransick , Steven G. Hall , John A. Hibner , Julia J. Hwang , Yolanda F. Carter , Frederick E. Shelton, IV
IPC分类号： A61B17/22 , A61B17/00
CPC分类号： A61B17/0057 , A61B10/0283 , A61B17/00491 , A61B17/32002 , A61B17/320758 , A61B18/1492 , A61B2017/00623 , A61B2017/00641 , A61B2017/00654 , A61B2017/00867 , A61B2017/00893 , A61B2017/00969 , A61B2017/22067 , A61B2017/320064 , A61B2217/005 , A61B2217/007 , A61M1/0084
摘要： A fistula repair system includes a debriding member that may be inserted into a fistula to debride the fistula wall. The debriding member may include a plurality of selectively extendable barbs. The barbs may be hollow to deliver a medical fluid within the fistula. The debriding member may also include a plurality of openings configured to communicate the medical fluid within the fistula. The barbs may extend through the openings. The openings may include associated protrusions that are configured to debride the fistula wall. The medical fluid may include a slurry of tissue and a scaffold material. The tissue in the slurry may comprise minced tissue that was harvested from the patient afflicted with the fistula. A balloon may be used to at least temporarily seal one end of the fistula. An RF probe or mechanical hook member may be used to seal the other end of the fistula.
摘要翻译：瘘修复系统包括可以插入瘘管以清除瘘管壁的清创构件。清创构件可以包括多个可选择性地可延伸的倒钩。倒钩可以是中空的，以在瘘管内输送医用流体。解围构件还可以包括多个开口，其被构造成在瘘管内传送医用流体。倒钩可以延伸穿过开口。开口可以包括被配置为清除瘘管壁的相关联的突起。医用流体可以包括组织和支架材料的浆液。浆液中的组织可以包括从患有瘘管的患者收获的切碎的组织。可以使用气囊来至少临时密封瘘的一端。可以使用RF探针或机械钩构件来密封瘘的另一端。

72. 发明申请

US20110282337A1 Instrument for Debriding Fistula and Applying Therapeutic Cells 有权
标题翻译：用于清除瘘管和应用治疗细胞的仪器
公开(公告)号：US20110282337A1
公开(公告)日：2011-11-17
申请号：US12778671
申请日：2010-05-12
申请人： Steven G. Hall , John A. Hibner , Julia J. Hwang , Yolanda F. Carter
发明人： Steven G. Hall , John A. Hibner , Julia J. Hwang , Yolanda F. Carter
IPC分类号： A61B18/18 , A61B17/3205
CPC分类号： A61B17/00491 , A61B10/0266 , A61B10/0283 , A61B17/0057 , A61B17/32002 , A61B18/1492 , A61B2017/00398 , A61B2017/00623 , A61B2017/00641 , A61B2017/00654 , A61B2017/00893 , A61B2017/00969 , A61B2017/320004 , A61B2017/320775 , A61B2018/1472 , A61B2217/005 , A61B2217/007 , A61M1/0084
摘要： A treatment system comprises an outer sheath and an end effector. The end effector has a plurality of cutting features, at least a portion of which are configured to debride a tissue surface when the end effector is actuated. The cutting features may also be configured to harvest tissue. A medical fluid reservoir is in fluid communication with the end effector, such that the end effector may deliver a medical fluid to a target site such as a fistula. The medical fluid may include harvested tissue cells and a scaffold material. A vacuum cannula may be positioned coaxially within the interior cavity of the end effector, and an RF probe may be positioned co-axially within the interior cavity of the vacuum cannula. The vacuum cannula and RF probe may be used together to seal a fistula in which medical fluid has been dispensed.
摘要翻译：治疗系统包括外鞘和末端执行器。末端执行器具有多个切割特征，其至少一部分被配置为当端部执行器被致动时清除组织表面。切割特征也可以被配置成收获组织。医疗液体储存器与末端执行器流体连通，使得末端执行器可将医疗流体输送到诸如瘘的目标部位。医疗流体可以包括收获的组织细胞和支架材料。真空插管可以同轴地定位在端部执行器的内部空腔内，并且RF探针可以同轴地定位在真空插管的内部空腔内。真空插管和RF探针可以一起使用以密封已经分配了药液的瘘管。

73. 发明申请

US20110208087A1 Tissue Harvesting, Mincing, and Transport Device 失效
标题翻译：组织收获，挖掘和运输装置
公开(公告)号：US20110208087A1
公开(公告)日：2011-08-25
申请号：US12709738
申请日：2010-02-22
申请人： Michael J. Trezza, II , John A. Hibner , Joseph C. Hueil , Patrick A. Mescher
发明人： Michael J. Trezza, II , John A. Hibner , Joseph C. Hueil , Patrick A. Mescher
IPC分类号： A61B10/02
CPC分类号： A61B17/320016 , A61B10/0275 , A61B10/0283 , A61B2010/0208
摘要： A device comprises a needle, probe, holster, and tissue collection chamber. A motor simultaneously powers a vacuum pump, translates and rotates a cutter, and translates a plunger. The needle includes a piercing tip and an interior shelf that divides the needle into a cutter lumen and lateral lumen. The cutter and shelf include apertures configured to mince a portion of a tissue specimen that has been severed by the cutter and forced through the apertures by compressive force from the plunger as well as vacuum force. The apertures of the shelf and the apertures of the rotating cutter cooperate to shear the tissue being compressed by the plunger. The minced tissue is then transported to the tissue collection chamber under vacuum force with the assistance of a fluid flush. Collected minced tissue may then be further processed as desired for a given medical treatment or procedure.
摘要翻译：一种装置包括针，探针，皮套和组织收集室。马达同时为真空泵供电，平移和旋转切割器，并平移柱塞。针包括穿刺尖端和将针分成切割器腔和侧腔的内部搁架。切割器和搁板包括孔，该孔被构造成切割由切割器切断的组织样本的一部分，并通过来自柱塞的压力强制通过孔以及真空力。搁板的孔和旋转切割器的孔协作以剪切被柱塞压缩的组织。然后在液体冲洗的帮助下，将切碎的组织在真空力下输送到组织收集室。然后可以根据需要进一步处理收集的切碎的组织用于给定的医疗处理或程序。

74. 发明申请

US20110092848A1 MRI Biopsy Targeting Cube with Eccentric Lock 有权
标题翻译： MRI偏心锁定活检靶向立方体
公开(公告)号：US20110092848A1
公开(公告)日：2011-04-21
申请号：US12580292
申请日：2009-10-16
申请人： John A. Hibner , Anil R. Jadhav , Nitin P. Wale , Santosh G. Deshmukh , Ajay D. Pawar , Abhijit G. Kulkarni
发明人： John A. Hibner , Anil R. Jadhav , Nitin P. Wale , Santosh G. Deshmukh , Ajay D. Pawar , Abhijit G. Kulkarni
IPC分类号： A61B10/02
CPC分类号： A61B90/17 , A61B10/0275 , A61B90/11 , A61B2017/00796 , A61B2017/00911 , A61B2017/3407 , A61B2017/3411 , A61B2090/034 , A61B2090/374
摘要： A biopsy system comprises a control module, a localization assembly, a biopsy device, and a targeting cube. A probe and/or other associated components of the biopsy device are configured to selectively couple with the targeting cube, which is configured to selectively couple with a grid plate. The targeting cube may comprise an eccentric lock for securing the targeting cube within the grid plate. The targeting cube may further comprise an elastomeric insert positioned within guide holes of the targeting cube for securing the probe and/or other associated components within the guide hole of the targeting cube. The guide holes of the targeting cube may alternatively, or in addition, include an elastomeric retaining ring within the passageway of the guide hole.
摘要翻译：活检系统包括控制模块，定位组件，活检装置和靶向立方体。活检装置的探针和/或其它相关组件被配置为选择性地与靶向立方体耦合，所述靶向立方体被配置为选择性地与栅板连接。靶向立方体可以包括偏心锁，用于将瞄准立方体固定在格板内。定向立方体还可以包括定位在瞄准立方体的引导孔内的弹性体插入件，用于将探针和/或其它相关部件固定在目标立方体的引导孔内。定向立方体的引导孔可以替代地或另外在引导孔的通道内包括弹性保持环。

75. 发明申请

US20110092847A1 MRI Biopsy Targeting Cube with Snap Corners 有权
标题翻译： MRI活检靶向立方体
公开(公告)号：US20110092847A1
公开(公告)日：2011-04-21
申请号：US12580288
申请日：2009-10-16
申请人： Nitin P. Wale , Santosh G. Deshmukh , Anil R. Jadhav , Ajay D. Pawar , Abhijit G. Kulkarni , John A. Hibner
发明人： Nitin P. Wale , Santosh G. Deshmukh , Anil R. Jadhav , Ajay D. Pawar , Abhijit G. Kulkarni , John A. Hibner
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B90/11 , A61B90/17 , A61B2017/00796 , A61B2017/3407 , A61B2017/3411
摘要： A biopsy system comprises a control module, a localization assembly, a biopsy device, and a targeting cube. The biopsy device and/or other associated components are configured to selectively couple with a targeting cube that selectively couples with a grid plate having apertures for receiving the cube. The targeting cube comprises a body defined by faces. The targeting cube further comprises guide holes that originate and terminate at the faces and pass through the body of the targeting cube to provide passageways through the cube. To securely and removably fit the targeting cube within a grid plate aperture, the targeting cube also comprises deflectable projections positioned at the corners of the cube or extending from the faces of the cube. The projections are resiliently biased to extend outwardly, and are inwardly deflectable by the walls of a grid plate aperture to secure the targeting cube in position within the aperture.
摘要翻译：活检系统包括控制模块，定位组件，活检装置和靶向立方体。活检装置和/或其它相关联的部件被配置为选择性地与定向立方体耦合，所述靶向立方体选择性地与具有用于接收立方体的孔的格栅板耦合。定向立方体包括由面定义的主体。瞄准立方体还包括引导孔，其引导并终止在面部并且穿过定向立方体的主体以提供通过立方体的通道。为了将瞄准立方体可靠地并且可拆卸地装配在网格板孔内，目标立方体还包括位于立方体角部或从立方体的表面延伸的可偏转突起。突起被弹性地偏压以向外延伸，并且可由栅格板孔的壁向内偏转，以将瞄准立方体固定在孔内的适当位置。

76. 发明申请

US20110082364A1 MRI Biopsy Targeting Cube with Retention Wiper 审中-公开
标题翻译：磁共振活检靶向立方体保留雨刷
公开(公告)号：US20110082364A1
公开(公告)日：2011-04-07
申请号：US12573177
申请日：2009-10-05
申请人： John A. Hibner , Kreena Avimukta , Kevin R. Shannon
发明人： John A. Hibner , Kreena Avimukta , Kevin R. Shannon
IPC分类号： A61B5/055 , A61B10/02
CPC分类号： A61B90/17 , A61B5/055 , A61B10/0266 , A61B90/11 , A61B2017/00796 , A61B2017/3407 , A61B2017/3411
摘要： A biopsy system comprises a localization assembly, a biopsy device, and a targeting cube. At least a portion of the biopsy device is insertable through a targeting cube, which is insertable into a selected aperture of a grid plate. The targeting cube comprises a body defined by faces, with guide passageways that originate and terminate at the faces and pass through the body of the targeting cube to accommodate insertion of a part of the biopsy device. An exterior wiper retainer of the targeting cube engages the grid plate to permit insertion of the targeting cube into a selected aperture of the grid plate while resisting withdrawal of the targeting cube from the grid plate. Internal wiper retainers in the guide passageways permit insertion of part of the biopsy device through a selected guide passageway while resisting withdrawal of the inserted part from the targeting cube.
摘要翻译：活检系统包括定位组件，活检装置和靶向立方体。活检装置的至少一部分可插入通过靶向立方体，该定向立方体可插入网格板的所选择的孔中。靶向立方体包括由面限定的主体，引导通道起始并终止于面并且穿过定向立方体的主体以适应插入活检装置的一部分。瞄准立方体的外部刮水器保持器与栅格板接合，以允许将靶向立方体插入格栅板的选定的孔中，同时阻止目标立方体从格栅板中取出。引导通道中的内部刮水器保持器允许穿过所选择的引导通道插入活检装置的一部分，同时阻止插入部件从定向立方体中取出。

77. 发明申请

US20110054349A1 CLUTCH AND VALVING SYSTEM FOR TETHERLESS BIOPSY DEVICE 有权
标题翻译：用于无菌生物装置的离合器和阀门系统
公开(公告)号：US20110054349A1
公开(公告)日：2011-03-03
申请号：US12944037
申请日：2010-11-11
申请人： John A. Hibner
发明人： John A. Hibner
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B10/0266 , A61B10/0283 , A61B2010/0208 , A61B2017/00398
摘要： A biopsy device may include a needle, a cutter, and a handpiece. A vacuum pump may be provided in the handpiece for providing a vacuum to the needle and/or to the cutter. A motor may be provided in the handpiece to drive the vacuum pump and/or the cutter. A biopsy device may also include a valving mechanism within the handpiece for selectively communicating a vacuum and/or atmospheric air to the needle. A clutching mechanism may selectively provide communication between a motor and the cutter. Portions of a valving mechanism and a clutching mechanism may be integrally formed. A clutching and valving mechanism may be driven by a first motor; and a cutter and vacuum pump by a second motor. A biopsy device may include batteries for powering motors. A biopsy device may thus provide vacuum and power from within a handpiece, such that the biopsy device is tetherless.
摘要翻译：活检装置可以包括针，切割器和手持件。可以在手持件中设置真空泵，以向针和/或切割器提供真空。可以在手持件中设置电动机以驱动真空泵和/或切割器。活检装置还可以包括用于选择性地将真空和/或大气空气连通到针的手持件内的阀机构。离合机构可以选择性地提供电动机和切割器之间的连通。阀机构和离合机构的一部分可以一体地形成。离合器和阀门机构可由第一马达驱动; 以及通过第二电动机的切割器和真空泵。活检装置可以包括为电动机供电的电池。因此，活检装置可以从手持件内提供真空和动力，使得活检装置是无连接的。

78. 发明授权

US07828748B2 Vacuum syringe assisted biopsy device 有权
标题翻译：真空注射器辅助活检装置
公开(公告)号：US07828748B2
公开(公告)日：2010-11-09
申请号：US11465143
申请日：2006-08-17
申请人： John A. Hibner
发明人： John A. Hibner
IPC分类号： A61B10/00
CPC分类号： A61B10/0283 , A61B10/0275 , A61B2010/0208 , A61B2010/0225 , A61B2017/0046
摘要： A biopsy device and method are provided for obtaining a tissue sample, such as a breast tissue biopsy sample. The biopsy device includes a disposable probe assembly with an outer cannula having a distal piercing tip, a cutter lumen, and a cutter tube that rotates and translates past a side aperture in the outer cannula to sever a tissue sample. The biopsy device also includes a reusable handpiece with an integral motor and power source to make a convenient, untethered control for use with ultrasonic imaging. The reusable handpiece incorporates a probe oscillation mode to assist when inserting the distal piercing tip into tissue. The motor also actuates a vacuum syringe in coordination with movement of the cutter tube to provide vacuum assistance in prolapsing tissue and retracting tissue samples.
摘要翻译：提供活检装置和方法来获得诸如乳房组织活组织检查样本的组织样本。活检装置包括具有外插管的一次性探针组件，该外套管具有远端穿刺尖端，切割器内腔和切割管，其旋转并平移穿过外插管中的侧孔以切断组织样本。活检装置还包括具有集成电机和电源的可重复使用的手持件，以便使用于超声波成像的方便，无阻塞的控制。可重复使用的手持件包含探针振动模式，以在将远端穿刺尖端插入组织中时有助于。电动机还与切割管的运动协调地致动真空注射器，以在脱垂组织中提取真空辅助并缩回组织样本。

79. 发明申请

US20100113971A1 Biopsy Device with Translating Valve Mechanism 有权
标题翻译：具有翻转阀机构的活检装置
公开(公告)号：US20100113971A1
公开(公告)日：2010-05-06
申请号：US12685721
申请日：2010-01-12
申请人： John A. Hibner
发明人： John A. Hibner
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B10/0283 , A61B10/04 , A61B2010/0208 , A61B2010/0225 , A61B2017/0023 , A61B2017/00398 , A61B2017/0046 , A61B2017/00734 , A61B2217/005 , A61B2217/007
摘要： A biopsy device comprises a cannula having a transverse tissue receiving aperture and a cutter that is movable relative to the cannula to sever tissue protruding through the aperture. A first valve assembly comprises a first valve body and a first actuator. The first valve body has a first port, a second port, and a third port. The first port is in fluid communication with either atmospheric air or a pressurized medium. The second port is in fluid communication with the cannula. The third port is in fluid communication with a vacuum source. The first actuator is translatable relative to the first valve body to selectively couple either the first port or the third port with the second port. An optional second valve assembly is operable to selectively couple the cannula with either a source of saline or the first valve assembly.
摘要翻译：活检装置包括具有横向组织接收孔的插管和可相对于套管移动的切割器，以切断通过该孔突出的组织。第一阀组件包括第一阀体和第一致动器。第一阀体具有第一端口，第二端口和第三端口。第一个端口与大气或加压介质流体连通。第二端口与套管流体连通。第三个端口与真空源流体连通。第一致动器可相对于第一阀体平移，以选择性地将第一端口或第三端口与第二端口耦合。可选的第二阀组件可操作以选择性地将套管与盐水源或第一阀组件连接。

80. 发明申请

US20090281453A1 MRI Biopsy Apparatus Incorporating a Sleeve and Multi-Function Obturator 审中-公开
标题翻译：结合套管和多功能闭塞器的MRI活检装置
公开(公告)号：US20090281453A1
公开(公告)日：2009-11-12
申请号：US12467347
申请日：2009-05-18
申请人： Mark Tsonton , Timothy G. Dietz , John A. Hibner , Jessica M. Pyzoha , Michael J. Andreyko , Keshava Datta , Michael A. Murray
发明人： Mark Tsonton , Timothy G. Dietz , John A. Hibner , Jessica M. Pyzoha , Michael J. Andreyko , Keshava Datta , Michael A. Murray
IPC分类号： A61B10/02
CPC分类号： A61B10/02 , A61B5/055 , A61B5/0555 , A61B10/0041 , A61B10/0233 , A61B10/0275 , A61B10/0283 , A61B17/3403 , A61B17/3417 , A61B17/3421 , A61B90/11 , A61B90/17 , A61B2010/0208 , A61B2010/0225 , A61B2017/00477 , A61B2017/00796 , A61B2017/00911 , A61B2017/3411 , A61B2090/034 , A61B2090/036 , A61B2090/374 , A61B2090/3908 , A61B2090/3933 , A61B2090/3954 , A61B2090/3987
摘要： A localization mechanism, or fixture, is used in conjunction with a breast coil for breast compression and for guiding a core biopsy instrument during prone biopsy procedures in both open and closed Magnetic Resonance Imaging (MRI) machines. The localization fixture includes a three-dimensional Cartesian positionable guide for supporting and orienting an MRI-compatible biopsy instrument, and in particular a sleeve, to a biopsy site of suspicious tissues or lesions. A depth stop enhances accurate insertion, and prevents over-insertion or inadvertent retraction of the sleeve. The sleeve receives a probe of the MRI-compatible biopsy instrument and may contain various features to enhance its imageability, to enhance vacuum and pressure assist therethrough, and marker deployment etc.
摘要翻译：定位机构或夹具与乳房线圈一起用于乳房压缩，并用于在开放和闭合的磁共振成像（MRI）机器中的易行活检过程中引导核心活检仪器。定位固定装置包括一个三维笛卡尔定位指南，用于支持和定向MRI兼容的活检仪器，特别是套筒，用于可疑组织或病变的活检部位。深度限位器可以提高精确的插入，并防止套筒的过度插入或无意的收回。袖子接受MRI相容性活检仪器的探针，并且可以包含各种特征以增强其可成像性，以增强真空和通过其中的压力辅助和标记部署等。

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