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71. 发明授权

US07956189B2 Maleate, tosylate, fumarate and oxalate salts of 5-(1-(S)-amino-2-hydroxyethyl)-N-[(2,4-difluorophenyl)-methy]-2-[8-methoxy-2-(triflouromethy)-5-quinoline]-4-oxazolecarboxamide and preparation process therefore 失效
标题翻译： 5-（1-（S） - 氨基-2-羟乙基）-N - [（2,4-二氟苯基） - 甲基] -2- [8-甲氧基-2-（三氟甲基）三氟甲磺酸盐，马来酸盐，甲苯磺酸盐，富马酸盐和草酸盐）-5-喹啉] -4-氧杂二甲酰胺及其制备方法
公开(公告)号：US07956189B2
公开(公告)日：2011-06-07
申请号：US11891351
申请日：2007-08-10
申请人： Xiaoming Chen , Xiao Chen , Jianguo Yin , Xiaoyong Fu , David J. Blythin , Rongze Kuang , Ho-Jane Shue , Scott Trzaska , Chee-Wah Tang , Vincenzo Liotta , Zaher Shabani
发明人： Xiaoming Chen , Xiao Chen , Jianguo Yin , Xiaoyong Fu , David J. Blythin , Rongze Kuang , Ho-Jane Shue , Scott Trzaska , Chee-Wah Tang , Vincenzo Liotta , Zaher Shabani
IPC分类号： C07D215/38
CPC分类号： C07D413/04
摘要： Disclosed are maleate, tosylate, fumarate, and oxalate salts of the compound 5-(1(S)-Amino-2-Hydroxyethyl)-N-[(2,4-Difluorophenyl)-Methyl]-2-[8-Methoxy-2-(Trifluoromethyl)-5-Quinoline]-4-Oxazolecarboxamide, represented by Formula I, and methods of preparing the same.
摘要翻译：公开了化合物5-（1（S） - 氨基-2-羟乙基）-N - [（2,4-二氟苯基） - 甲基] -2- [8-甲氧基 - 由式I表示的2-（三氟甲基）-5-喹啉啉-4-氧杂二甲酰胺及其制备方法。

72. 发明授权

US07912830B2 Knowledge portal for accessing, analyzing and standardizing data 失效
标题翻译：访问，分析和标准化数据的知识门户
公开(公告)号：US07912830B2
公开(公告)日：2011-03-22
申请号：US12052978
申请日：2008-03-21
申请人： Xiao Chen , Erh-An Huang , Scott Milkovich , Eugene Rider
发明人： Xiao Chen , Erh-An Huang , Scott Milkovich , Eugene Rider
IPC分类号： G06F17/30
CPC分类号： G06F17/30554 , G06F17/30398 , G06F17/30569 , G06F19/00 , G06Q10/02 , G06Q40/00 , G06Q40/025 , G06Q50/22 , G06Q50/24 , G16H10/60 , G16H50/70 , Y10S128/92 , Y10S707/99933 , Y10S707/99934
摘要： A method and system is provided to access one or more historical incident databases, for example, CDC, CPSC, DTI, AAPCC and the like, for standardizing the potentially differing categories and coding among the databases. The standardizing includes recoding of the categories by providing a unified set of categories reflective of similar categories found among the one or more databases, if any. Submission of search queries allows users to obtain unified data across the databases so that incident history statistics for one or more products tracked by commonly available databases may be easily acquired. The resulting reports and statistics may be used by various entities to understand historical incidents from multiple perspectives including, for example, injury and fatality statistics as a function of age group, type of injury, time periods, diagnosis, injury outcome, severity, and the like. Data may be presented in standardized formats or in any of the native database formats.
摘要翻译：提供了一种用于访问一个或多个历史事件数据库（例如CDC，CPSC，DTI，AAPCC等）的方法和系统，用于标准化数据库中潜在的不同类别和编码。标准化包括通过提供反映在一个或多个数据库（如果有的话）中找到的类似类别的统一的一组类别来重新编码类别。提交搜索查询允许用户跨数据库获取统一的数据，以便可以轻松获取通常可用数据库跟踪的一个或多个产品的事件历史统计信息。所得到的报告和统计数据可能被各实体用于从多个角度了解历史事件，包括例如作为年龄组，伤害类型，时间段，诊断，伤害结果，严重程度的损伤和死亡统计数据，以及喜欢。数据可以以标准格式或任何本地数据库格式呈现。

73. 发明授权

US07763623B2 Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia 失效
标题翻译：杂环作为治疗血脂异常的烟酸受体激动剂
公开(公告)号：US07763623B2
公开(公告)日：2010-07-27
申请号：US11654137
申请日：2007-01-17
申请人： Anandan Palani , Jun Qin , Dong Xiao , Ying R. Huang , Xiao Chen , Zhidan Liu , Sylvia J. Degrado , Robert G. Aslanian , Xianhai Huang
发明人： Anandan Palani , Jun Qin , Dong Xiao , Ying R. Huang , Xiao Chen , Zhidan Liu , Sylvia J. Degrado , Robert G. Aslanian , Xianhai Huang
IPC分类号： C07D491/052 , A61K31/519 , A61P9/00 , A61P25/00 , A61P7/00 , A61P35/00 , A61P29/00 , A61P11/00 , A61P1/00 , A61P3/10
CPC分类号： C07D491/04
摘要： A compound having the general structure of Formula (I): or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, are useful in treating diseases, disorders, or conditions such as metabolic syndrome and dyslipidemia.
摘要翻译：具有式（I）的一般结构的化合物或其药学上可接受的盐，溶剂合物，酯或互变异构体可用于治疗疾病，病症或病症如代谢综合征和血脂异常。

74. 发明授权

US07723342B2 Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia 有权
标题翻译：杂环作为治疗血脂异常的烟酸受体激动剂
公开(公告)号：US07723342B2
公开(公告)日：2010-05-25
申请号：US11432133
申请日：2006-05-11
申请人： Anandan Palani , Jing Su , Dong Xiao , Xianhai Huang , Ashwin U. Rao , Xiao Chen , Haiqun Tang , Jun Qin , Ying Huang , Robert G. Aslanian , Brian A. McKittrick
发明人： Anandan Palani , Jing Su , Dong Xiao , Xianhai Huang , Ashwin U. Rao , Xiao Chen , Haiqun Tang , Jun Qin , Ying Huang , Robert G. Aslanian , Brian A. McKittrick
IPC分类号： C07D491/052 , A61K31/519 , A61P35/00 , A61P29/00 , A61P3/10 , A61P9/00 , A61P11/00
CPC分类号： C07D471/04 , C07D491/04 , C07D491/052
摘要： A compound having the general structure of Formula (I): or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, wherein: Q is selected from the group consisting of: and L is selected from the group consisting of: or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, are useful in treating diseases, disorders, or conditions such as metabolic syndrome and dyslipidemia.
摘要翻译：具有式（I）的通式结构的化合物或其药学上可接受的盐，溶剂化物，酯或互变异构体，其中：Q选自：和L选自：或其药学上可接受的盐可接受的盐，溶剂合物，酯或互变异构体，可用于治疗疾病，病症或病症如代谢综合征和血脂异常。

75. 发明授权

US07682940B2 Use of Cl2 and/or HCl during silicon epitaxial film formation 有权
标题翻译：在硅外延膜形成期间使用Cl2和/或HCl
公开(公告)号：US07682940B2
公开(公告)日：2010-03-23
申请号：US11227974
申请日：2005-09-14
申请人： Zhiyuan Ye , Yihwan Kim , Xiaowei Li , Ali Zojaji , Nicholas C. Dalida , Jinsong Tang , Xiao Chen , Arkadii V. Samoilov
发明人： Zhiyuan Ye , Yihwan Kim , Xiaowei Li , Ali Zojaji , Nicholas C. Dalida , Jinsong Tang , Xiao Chen , Arkadii V. Samoilov
IPC分类号： H01L21/20 , H01L21/36
CPC分类号： H01L21/02639 , H01L21/02381 , H01L21/02447 , H01L21/0245 , H01L21/02529 , H01L21/02532 , H01L21/02576 , H01L21/02579 , H01L21/0262
摘要： In a first aspect, a first method of forming an epitaxial film on a substrate is provided. The first method includes (a) providing a substrate; (b) exposing the substrate to at least a silicon source so as to form an epitaxial film on at least a portion of the substrate; and (c) exposing the substrate to HCl and Cl2 so as to etch the epitaxial film and any other films formed during step (b). Numerous other aspects are provided.
摘要翻译：在第一方面，提供了在基板上形成外延膜的第一种方法。第一种方法包括（a）提供基底; （b）将所述衬底暴露于至少硅源，以在所述衬底的至少一部分上形成外延膜; 和（c）将衬底暴露于HCl和Cl2，以蚀刻外延膜和在步骤（b）中形成的任何其它膜。提供了许多其他方面。

76. 发明授权

US07511062B2 Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors 失效
标题翻译：用作PDE4抑制剂的取代的2-喹啉基 - 恶唑
公开(公告)号：US07511062B2
公开(公告)日：2009-03-31
申请号：US11130359
申请日：2005-05-16
申请人： Rongze Kuang , David Blythin , Neng-Yang Shih , Ho-Jane Shue , Xiao Chen , Jianhua Cao , Danlin Gu , Ying Huang , John H. Schwerdt , Pauline C. Ting , Shing-Chun Wong , Li Xiao
发明人： Rongze Kuang , David Blythin , Neng-Yang Shih , Ho-Jane Shue , Xiao Chen , Jianhua Cao , Danlin Gu , Ying Huang , John H. Schwerdt , Pauline C. Ting , Shing-Chun Wong , Li Xiao
IPC分类号： C07D215/38 , A61K31/44
CPC分类号： C07D405/14 , C07D401/04 , C07D405/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14
摘要： The invention claims compounds of the formula wherein is a 5-membered heteroaryl; X is S or O; R1 is H, alkyl, cycloalkyl, cylcoalkylalkyl-, —CH2F, —CHF2, —CF3, —C(O)alkyl or —C(O)NR18R19; R3 and R4 H, alkyl, hydroxyalkyl or —C(O)Oalkyl; R5 and R6 are H, alkyl, hydroxyalkyl, alkoxyalkyl, mercaptoalkyl, —CH2F, —CHF2, —CF3, —C(O)OH or —C(O)Oalkyl; R7 is H, alkyl, alkenyl, hydroxyalkyl, cycloalkyl, alkoxyalkyl, aminoalkyl, (R17-phenyl)alkyl or —CH2—C(O)—O-alkyl; and R8 comprises alkyl, heteroaryl, phenyl or cycloalkyl, or heterocycloalkyl, all optionally substituted, or a cycloalkyl- or heterocycloalkyl-substituted amide; or R7 and R8 and the nitrogen to which they are attached together form an optionally substituted ring; and the remaining variables are as defined in the specification. Also claimed are pharmaceutical compositions, the use of the compounds as PDE4 inhibitors, and combinations with other actives.
摘要翻译：本发明要求具有下式的化合物其中是5元杂芳基; X是S或O; R 1是H，烷基，环烷基，环烷基烷基 - ， - CH 2 F，-CHF 2，-CF 3，-C（O）烷基或-C（O）NR 18 R 19; R 3和R 4 H，烷基，羟基烷基或-C（O）O烷基; R5和R6是H，烷基，羟基烷基，烷氧基烷基，巯基烷基，-CH2F，-CHF2，-CF3，-C（O）OH或-C（O） R 7是H，烷基，烯基，羟基烷基，环烷基，烷氧基烷基，氨基烷基，（R 17 - 苯基）烷基或-CH 2 -C（O）-O-烷基; 和R8包括烷基，杂芳基，苯基或环烷基，或杂环烷基，全部任意取代，或环烷基 - 或杂环烷基取代的酰胺; 或R 7和R 8，并且与它们相连的氮一起形成任选取代的环; 其余变量如本说明书中所定义。还要求保护的是药物组合物，化合物作为PDE4抑制剂的用途，以及与其它活性物质的组合。

77. 发明申请

US20050171941A1 Knowledge portal for accessing, analyzing and standardizing data 失效
标题翻译：访问，分析和标准化数据的知识门户
公开(公告)号：US20050171941A1
公开(公告)日：2005-08-04
申请号：US10923691
申请日：2004-08-24
申请人： Xiao Chen , Erh-An Huang , Scott Milkovich , Eugene Rider
发明人： Xiao Chen , Erh-An Huang , Scott Milkovich , Eugene Rider
IPC分类号： G06F17/30 , G06F19/00 , G06F7/00
CPC分类号： G06F17/30554 , G06F17/30398 , G06F17/30569 , G06F19/00 , G06Q10/02 , G06Q40/00 , G06Q40/025 , G06Q50/22 , G06Q50/24 , G16H10/60 , G16H50/70 , Y10S128/92 , Y10S707/99933 , Y10S707/99934
摘要： A method and system is provided to access one or more historical incident databases, for example, CDC, CPSC, DTI, AAPCC and the like, for standardizing the potentially differing categories and coding among the databases. The standardizing includes recoding of the categories by providing a unified set of categories reflective of similar categories found among the one or more databases, if any. Submission of search queries allows users to obtain unified data across the databases so that incident history statistics for one or more products tracked by commonly available databases may be easily acquired. The resulting reports and statistics may be used by various entities to understand historical incidents from multiple perspectives including, for example, injury and fatality statistics as a function of age group, type of injury, time periods, diagnosis, injury outcome, severity, and the like. Data may be presented in standardized formats or in any of the native database formats.
摘要翻译：提供了一种用于访问一个或多个历史事件数据库（例如CDC，CPSC，DTI，AAPCC等）的方法和系统，用于标准化数据库中潜在的不同类别和编码。标准化包括通过提供反映在一个或多个数据库（如果有的话）中找到的类似类别的统一的一组类别来重新编码类别。提交搜索查询允许用户跨数据库获取统一的数据，以便可以轻松获取通常可用数据库跟踪的一个或多个产品的事件历史统计信息。所得到的报告和统计数据可能被各个实体用于从多个角度了解历史事件，包括例如作为年龄组，伤害类型，时间段，诊断，伤害结果，严重程度的损伤和死亡统计数据，以及喜欢。数据可以以标准格式或任何本地数据库格式呈现。

78. 发明申请

US20050159840A1 System for surface finishing a workpiece 审中-公开
标题翻译：用于表面处理工件的系统
公开(公告)号：US20050159840A1
公开(公告)日：2005-07-21
申请号：US10758949
申请日：2004-01-16
申请人： Wen-Jong Lin , Xiao Chen , Zhiming Gong
发明人： Wen-Jong Lin , Xiao Chen , Zhiming Gong
IPC分类号： G05B19/416 , G06F19/00
CPC分类号： G05B19/4163 , B23P6/002 , G05B2219/37355 , G05B2219/39322 , G05B2219/42092 , G05B2219/45151
摘要： A system is provided for finishing a surface of a workpiece, for instance by abrading a brazed area or welded area to remove excess brazed or weld material during the refurbishment of the turbine blade. A real-time control system has a controlled material removal rate strategy where a computer controls the different contact or polishing forces in real-time to achieve high accuracy.
摘要翻译：提供了一种用于完成工件表面的系统，例如通过在涡轮叶片翻新期间研磨钎焊区域或焊接区域以去除多余的钎焊或焊接材料。实时控制系统具有受控的材料去除率策略，其中计算机实时控制不同的接触或抛光力以实现高精度。

79. 发明申请

US20050093847A1 Haptic response system and method of use 失效
标题翻译：触觉反应系统及使用方法
公开(公告)号：US20050093847A1
公开(公告)日：2005-05-05
申请号：US10941088
申请日：2004-09-15
申请人： Robert Altkorn , Xiao Chen , Scott Milkovich , John Owens , Brian Rider , Eugene Rider , Daniel Stool
发明人： Robert Altkorn , Xiao Chen , Scott Milkovich , John Owens , Brian Rider , Eugene Rider , Daniel Stool
IPC分类号： G06F3/00 , G06F3/01 , G09G5/00 , G09G5/08
CPC分类号： G06F3/048 , G06F3/016
摘要： An apparatus and method for assessing a hazard associated with an object are disclosed. The apparatus includes a haptic input/output device coupled to a computer with haptic modeling software and a display device. A virtual object and a virtual passageway are displayed on the display device. The virtual passageway includes a haptic layer along a surface thereof. Force applied by a user to the haptic input/output device causes a cursor on the display device to move the virtual object into the virtual passageway. An interaction of the virtual object with the haptic layer generates a virtual contact force which may be determined by the user sensing a corresponding tactile feedback force generated by the haptic input/output device and/or by the computer processor. The magnitude of the virtual contact force may be used to assess a hazard associated with the virtual object.
摘要翻译：公开了一种用于评估与物体相关的危险的装置和方法。该装置包括利用触觉建模软件和显示装置耦合到计算机的触觉输入/输出装置。在显示装置上显示虚拟对象和虚拟通道。虚拟通道包括沿其表面的触觉层。由用户施加到触觉输入/输出设备的力使得显示设备上的光标将虚拟对象移动到虚拟通道中。虚拟对象与触觉层的交互产生虚拟接触力，虚拟接触力可以由用户感测由触觉输入/输出设备和/或计算机处理器产生的对应的触觉反馈力来确定。虚拟接触力的大小可用于评估与虚拟物体相关的危险。

80. 发明申请

US20050059279A1 Electrical connector with improved grounding structure 审中-公开
标题翻译：电连接器具有改进的接地结构
公开(公告)号：US20050059279A1
公开(公告)日：2005-03-17
申请号：US10940245
申请日：2004-09-13
申请人： Jing Zu , Chun Li , Xiao Chen , Feng Zhu
发明人： Jing Zu , Chun Li , Xiao Chen , Feng Zhu
IPC分类号： H01R12/16 , H01R4/66
CPC分类号： H01R13/6597
摘要： An electronic connector (1) includes a dielectric housing (10), a number of terminals (20) received in the dielectric housing, a shell (30) mounted on the dielectric housing, a spacer (50) and a pair of ground plates (40). The dielectric housing includes a base (11), a pair of brackets (13) extending downwardly from opposite ends of the base. Each bracket has a shoulder (132) defining a retention slit (1322) extending therethrough. The ground plates are received in the retention slits. The shell has a pair of cantilever arms (33) received in the retention slits and electrically connecting with the ground plates.
摘要翻译：电子连接器（1）包括绝缘壳体（10），容纳在电介质壳体中的多个端子（20），安装在介电壳体上的壳体（30），间隔件（50）和一对接地板 40）。绝缘壳体包括基部（11），从底座的相对端向下延伸的一对托架（13）。每个支架具有限定延伸穿过其中的保持狭缝（1322）的肩部（132）。接地板被容纳在保持狭缝中。壳体具有一对接纳在保持狭缝中并与接地板电连接的悬臂（33）。

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