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71. 发明授权

US08861391B1 Channel feedback for TDM scheduling in heterogeneous networks having multiple cell classes 有权
标题翻译：具有多个小区类的异构网络中TDM调度的信道反馈
公开(公告)号：US08861391B1
公开(公告)日：2014-10-14
申请号：US13409130
申请日：2012-03-01
申请人： Yan Zhang , Krishna Srikanth Gomadam
发明人： Yan Zhang , Krishna Srikanth Gomadam
IPC分类号： H04L1/00 , H04B7/06
CPC分类号： H04L1/0007 , H04B7/0619 , H04L1/0026 , H04L25/03949 , Y02D70/00 , Y02D70/1262 , Y02D70/444
摘要： A method includes receiving in a communication terminal a sequence of downlink frames from a communication network that includes multiple cells arranged in first and second layers. The first layer corresponds to a first class of cells selected from a group of classes consisting of macro-cells, micro-cells, pico-cells, femto-cells and low-power nodes (LPN). The second layer corresponds to a second class of cells, different from the first class. One or more cross-layer frames in which at least a first cell in the first layer and at least a second cell in the second layer transmit data, and one or more same-layer frames in which only one or more of the cells in a single layer that currently serves the terminal transmit the data, are identified in the sequence. Cross-layer channel feedback is calculated over the cross-layer frames, and same-layer channel feedback is calculated over the same-layer frames.
摘要翻译：一种方法包括在通信终端中接收包括布置在第一和第二层中的多个小区的通信网络的下行链路帧序列。第一层对应于从由宏小区，微小区，微微小区，毫微微小区和低功率节点（LPN）组成的组中选择的第一类小区。第二层对应于与第一类不同的第二类单元格。一个或多个跨层帧，其中第一层中的至少第一小区和第二层中的至少第二小区发送数据，以及一个或多个相同层帧，其中一个或多个单元当前服务于终端的单层发送数据，按顺序标识。在跨层帧上计算跨层信道反馈，并在相同层帧上计算同层信道反馈。

72. 发明申请

US20140243258A1 METHODS AND COMPOSITIONS FOR TARGETING ADIPOSE CELLS IN MAMMALS 有权
标题翻译：用于在哺乳动物中测定ADIPOSE细胞的方法和组合物
公开(公告)号：US20140243258A1
公开(公告)日：2014-08-28
申请号：US14007836
申请日：2012-03-30
申请人： Mikhail G. Kolonin , Alexes Daquinag , Yan Zhang
发明人： Mikhail G. Kolonin , Alexes Daquinag , Yan Zhang
IPC分类号： A61K47/48 , A61K38/10 , C07K7/06 , C07K7/64
CPC分类号： A61K47/48246 , A61K38/00 , A61K38/10 , A61K47/64 , C07K7/06 , C07K7/64 , C07K2319/00 , C07K2319/33
摘要： Methods and compositions are presented for use in diagnostic, imaging or targeting of therapeutic agents to treat obesity/adiposity-associated disorders, where such as compositions and methods identify and use peptides to selectively target adipose tissue stromal cells in mammals, both in vitro and in vivo.
摘要翻译：呈现方法和组合物用于诊断，成像或靶向治疗剂以治疗肥胖/肥胖相关疾病，其中例如组合物和方法鉴定和使用肽来选择性地靶向哺乳动物中的脂肪组织基质细胞，体外和体内。

73. 发明授权

US08761289B2 MIMO feedback schemes for cross-polarized antennas 有权
标题翻译：交叉极化天线的MIMO反馈方案
公开(公告)号：US08761289B2
公开(公告)日：2014-06-24
申请号：US12965878
申请日：2010-12-12
申请人： Adoram Erell , Krishna Srikanth Gomadam , Yan Zhang , Ezer Melzer
发明人： Adoram Erell , Krishna Srikanth Gomadam , Yan Zhang , Ezer Melzer
IPC分类号： H04B7/02 , H04L1/02
CPC分类号： H04B7/10 , H04B7/063 , H04B7/0641 , H04B7/0663
摘要： A method includes receiving a Multiple-Input Multiple Output (MIMO) signal over multiple communication channels from an antenna array including a first set of antennas having a first polarization and a second set of the antennas having a second polarization that is orthogonal to the first polarization. First feedback information is calculated relating to first interrelations between the antennas within either the first set or the second set. Second feedback information is calculated relating at least to second interrelations between the first set and the second set of the antennas. The first feedback information is transmitted at a first time/frequency granularity, and the second feedback information is transmitted at a second time/frequency granularity that is finer than the first time/frequency granularity.
摘要翻译：一种方法包括：从包括具有第一偏振的第一组天线的天线阵列的多个通信信道上接收多输入多输出（MIMO）信号，并且所述天线的第二组具有与第一极化正交的第二极化。计算与第一组或第二组内的天线之间的第一相互关系的第一反馈信息。计算第二反馈信息至少与第一组和第二组天线之间的第二相互关系。以第一时间/频率粒度发送第一反馈信息，并且以比第一时间/频率粒度更精细的第二时间/频率粒度发送第二反馈信息。

74. 发明申请

US20140128384A1 TUMOR TARGETED DRUG COMBRETASTATIN A4 DERIVATIVE 有权
标题翻译：肿瘤靶向药物组合A4衍生物
公开(公告)号：US20140128384A1
公开(公告)日：2014-05-08
申请号：US14127847
申请日：2012-07-04
申请人： Yong Wang , Cang Zhang , Xiaorong Liu , Yan Zhang , Yunyun Wang , Wenping Zhang
发明人： Yong Wang , Cang Zhang , Xiaorong Liu , Yan Zhang , Yunyun Wang , Wenping Zhang
IPC分类号： C07D413/04 , C07D277/24 , C07D263/32 , C07D233/64 , C07C251/24
CPC分类号： C07D413/04 , C07C251/24 , C07D233/64 , C07D263/32 , C07D277/22 , C07D277/24
摘要： The present invention relates to imidazole, oxazole and thiazole derivatives of tumor-targeted drug combretastatin A4, and phosphate esters, sulfonate esters or pharmaceutically acceptable salts, glycoside derivatives, solvates thereof, wherein the A-ring comprises a 3,5-dimethoxyphenyl group having a substituent at the 4-position. The pharmacological activity assays have demonstrated that the compounds of the present invention have good in vitro anti-tumor activity and excellent tubulin inhibitory effect.
摘要翻译：本发明涉及肿瘤靶向药物考布他汀A4的咪唑，恶唑和噻唑衍生物，以及磷酸酯，磺酸酯或其药学上可接受的盐，糖苷衍生物，溶剂合物，其中A环包含3,5-二甲氧基苯基， 4位的取代基。药理活性试验表明本发明化合物具有良好的体外抗肿瘤活性和优异的微管蛋白抑制作用。

75. 发明授权

US08692017B2 Carbon linked modulators of gamma-secretase 失效
标题翻译： γ-分泌酶的碳连接调节剂
公开(公告)号：US08692017B2
公开(公告)日：2014-04-08
申请号：US12253264
申请日：2008-10-17
申请人： Chih Yung Ho , Yan Zhang , Svenja Burckhardt , Alison Jones
发明人： Chih Yung Ho , Yan Zhang , Svenja Burckhardt , Alison Jones
IPC分类号： C07C63/33 , A01N43/40 , A61K31/435
CPC分类号： C07C59/88 , C07C57/42 , C07C57/58 , C07C57/60 , C07C59/56 , C07C255/57 , C07D213/61
摘要： The present invention relates to compounds of Formula I as shown below, wherein the definitions of A, X, R1, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.
摘要翻译：本发明涉及如下所示的式I化合物，其中A，X，R 1，R 3，R 4，R 5，R 6，R 7，R 8和R 9的定义在说明书中提供。式I化合物可用于治疗与γ-分泌酶活性相关的疾病，包括阿尔茨海默氏病。

76. 发明授权

US08680089B2 Fused pyridine derivatives 有权
标题翻译：融合吡啶衍生物
公开(公告)号：US08680089B2
公开(公告)日：2014-03-25
申请号：US13522304
申请日：2011-01-17
申请人： Zhenhua Huang , Yan Zhang , Yuntao Song
发明人： Zhenhua Huang , Yan Zhang , Yuntao Song
IPC分类号： C07D471/04 , A61K31/437 , A61K31/4545 , A61K31/4745 , A61K31/496 , A61K31/5377 , A61K31/55 , A61K31/551 , A61P3/06 , A61P3/08 , A61P3/10 , C07D498/04 , C07D513/04
CPC分类号： C07D471/04 , C07D498/04 , C07D513/04
摘要： Fused pyridine derivatives shown as the general formula (I), and their pharmaceutically acceptable salts, stereoisomers or solvates thereof are disclosed, which belong to the technical field of medicines. The R1, R2, R3, Q, X and Y substituents in formula (I) are defined as in the description. Also disclosed are the preparation methods, pharmaceutical compositions comprising the compounds and uses of the compounds in the manufacture of the medicine for the treatment and/or prevention of noninsulin-dependent diabetes, hyperglycemia, hyperlipidemia and insulin resistance.
摘要翻译：公开了以通式（I）表示的稠合吡啶衍生物及其药学上可接受的盐，立体异构体或溶剂化物，属于药物技术领域。式（I）中的R 1，R 2，R 3，Q，X和Y取代基如描述中所定义。还公开了制备方法，包含该化合物的药物组合物和该化合物在制备用于治疗和/或预防非胰岛素依赖型糖尿病，高血糖，高脂血症和胰岛素抵抗的药物中的用途。

77. 发明授权

US08466624B2 Electrohydrodynamic fluid accelerator device with collector electrode exhibiting curved leading edge profile 失效
标题翻译：电流动力学流体加速器装置，具有呈现弯曲前缘轮廓的收集器电极
公开(公告)号：US08466624B2
公开(公告)日：2013-06-18
申请号：US12553688
申请日：2009-09-03
申请人： Nels Jewell-Larsen , Kenneth A. Honer , Matt Schwiebert , Hongyu Ran , Piyush Savalia , Yan Zhang
发明人： Nels Jewell-Larsen , Kenneth A. Honer , Matt Schwiebert , Hongyu Ran , Piyush Savalia , Yan Zhang
IPC分类号： H05B31/26
CPC分类号： F28F13/16 , F28D15/02 , F28F2250/08 , H02N11/006
摘要： Performance of an electrohydrodynamic fluid accelerator device may be improved and adverse events such as sparking or arcing may be reduced based, amongst other things, on electrode geometries and/or positional interrelationships of the electrodes. For example, in a class of EHD devices that employ a longitudinally elongated corona discharge electrode (often, but not necessarily, a wire), a plurality of generally planar, collector electrodes may be positioned so as to present respective leading surfaces toward the corona discharge electrode. The generally planar collector electrodes may be oriented so that their major surfaces are generally orthogonal to the longitudinal extent of the corona discharge electrode. In such EHD devices, a high intensity electric field can be established in the “gap” between the corona discharge electrode and leading surfaces of the collector electrodes.
摘要翻译：电子流体动力学流体加速器装置的性能可以被改善，并且可以基于电极的电极几何形状和/或位置相互关系来减少不利的事件，例如火花或电弧。例如，在采用纵向长度电晕放电电极（通常但不一定是导线）的一类EHD装置中，可以将多个大体上平面的集电极定位成使得各自的前表面朝向电晕放电电极。大致平面的集电极可以被定向成使得它们的主表面大致垂直于电晕放电电极的纵向延伸。在这样的EHD装置中，可以在电晕放电电极和集电极的前表面之间的“间隙”中建立高强度电场。

78. 发明申请

US20130124753A1 FAIR QUANTIZED CONGESTION NOTIFICATION (FQCN) TO MITIGATE TRANSPORT CONTROL PROTOCOL (TCP) THROUGHPUT COLLAPSE IN DATA CENTER NETWORKS 有权
标题翻译：公平的量化协议通知（FQCN）在数据中心网络中减少运输控制协议（TCP）通过吞吐量
公开(公告)号：US20130124753A1
公开(公告)日：2013-05-16
申请号：US13297101
申请日：2011-11-15
申请人： Nirwan Ansari , Yan Zhang
发明人： Nirwan Ansari , Yan Zhang
IPC分类号： G06F15/16
CPC分类号： H04L47/263 , H04L47/30 , Y02D50/10
摘要： Technologies are generally described for an enhanced Quantized Congestion Notification (QCN) congestion control approach, referred to as Fair QCN (FQCN) for enhancing fairness of multiple flows sharing link capacity in a high bandwidth, low latency data center network. QCN messages may be fed back to flow sources (e.g., servers) which send packets with a sending rate over their share of the bottleneck link capacity. By enabling the flow sources to regulate their data traffic based on the QCN messages from a congestion control component, the queue length at the bottleneck link may converge to an equilibrium queue length rapidly and TCP throughput performance may be enhanced substantially in a TCP incast circumstance.
摘要翻译：技术通常被描述用于增强的量化拥塞通知（QCN）拥塞控制方法，称为公平QCN（FQCN），用于增强在高带宽，低延迟数据中心网络中共享链路容量的多个流的公平性。 QCN消息可以被反馈到以发送速率超过其瓶颈链路容量的份额发送分组的流源（例如，服务器）。通过使流量源能够根据来自拥塞控制组件的QCN消息来调节其数据流量，瓶颈链路上的队列长度可以快速收敛到平衡队列长度，并且TCP吞吐量性能可能在TCP恶劣情况下显着提高。

79. 发明授权

US08277986B2 Bipolar plate with microgrooves for improved water transport 有权
标题翻译：具有微槽的双极板，用于改善水的输送
公开(公告)号：US08277986B2
公开(公告)日：2012-10-02
申请号：US11772406
申请日：2007-07-02
申请人： Thomas A. Trabold , Gayatri Vyas Dadheech , Mahmoud H. Abd Elhamid , Yan Zhang , Keith E. Newman , Jeffrey A. Rock , Steven J. Spencer
发明人： Thomas A. Trabold , Gayatri Vyas Dadheech , Mahmoud H. Abd Elhamid , Yan Zhang , Keith E. Newman , Jeffrey A. Rock , Steven J. Spencer
IPC分类号： H01M8/02
CPC分类号： H01M8/026 , H01M8/0245 , H01M8/04171 , H01M8/04291 , H01M2008/1095 , Y10T29/49108
摘要： One embodiment of the invention comprises a fuel cell bipolar plate comprising a substrate comprising a first face, a reactant gas flow field defined in the first face, the reactant gas flow field comprising a plurality of lands and channels, and a plurality of microgrooves formed in the first face.
摘要翻译：本发明的一个实施例包括燃料电池双极板，其包括基板，该基板包括第一面，在第一面中限定的反应气体流场，反应物气流场包括多个平台和通道，以及多个微槽，第一张脸。

80. 发明授权

US08252935B2 Piperidinyl and piperazinyl modulators of γ-secretase 有权
标题翻译： γ-分泌酶的哌啶基和哌嗪基调节剂
公开(公告)号：US08252935B2
公开(公告)日：2012-08-28
申请号：US12251521
申请日：2008-10-15
申请人： Chih Yung Ho , Yan Zhang , Umar S. M. Maharoof , Jeremy Major , John Harrison
发明人： Chih Yung Ho , Yan Zhang , Umar S. M. Maharoof , Jeremy Major , John Harrison
IPC分类号： C07D211/08 , C07D237/00 , A61K31/497 , A61K31/445
CPC分类号： C07D295/155 , C07D211/18 , C07D211/38 , C07D241/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D417/06
摘要： The present invention relates to compounds of Formula I as shown below, wherein the definitions of Het, R0, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.
摘要翻译：本发明涉及如下所示的式I化合物，其中Het，R0，R1R2，R3，R4，R5，R6，R7，R8和R9的定义在说明书中提供。式I化合物可用于治疗与γ-分泌酶活性相关的疾病，包括阿尔茨海默氏病。

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