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71. 发明申请

US20050080093A1 Methods of reducing risk of infection from pathogens 失效
标题翻译：降低病原体感染风险的方法
公开(公告)号：US20050080093A1
公开(公告)日：2005-04-14
申请号：US10920484
申请日：2004-08-18
申请人： Michael Johnson , Samuel Hopkins
发明人： Michael Johnson , Samuel Hopkins
IPC分类号： A61K31/00 , A61K31/4965
CPC分类号： C07D241/30 , A61K31/00 , A61K31/4965 , C07D253/07 , Y02A50/402 , Y02A50/406 , Y02A50/463
摘要： Prophylactic treatment methods are provided for protection of individuals and/or populations against infection from airborne pathogens. In particular, prophylactic treatment methods are provided comprising administering a sodium channel blocker or pharmaceutically acceptable salts thereof to one or more members of a population at risk of exposure to or already exposed to one or more airborne pathogens, either from natural sources or from intentional release of pathogens into the environment.
摘要翻译：提供预防性治疗方法以保护个体和/或群体免受空气传播病原体的感染。特别地，提供了预防性治疗方法，其包括将钠通道阻断剂或其药学上可接受的盐给予暴露于或已经暴露于一种或多种空气传播病原体的风险的群体的一个或多个成员，所述病原体来自天然来源或有意释放的病原体进入环境。

72. 发明申请

US20050075333A1 CXCR3 antagonists 有权
标题翻译： CXCR3拮抗剂
公开(公告)号：US20050075333A1
公开(公告)日：2005-04-07
申请号：US10946935
申请日：2004-09-21
申请人： Julio Medina , Michael Johnson , An-Rong Li , Jiwen Liu , Alan Huang , Liusheng Zhu , Andrew Marcus
发明人： Julio Medina , Michael Johnson , An-Rong Li , Jiwen Liu , Alan Huang , Liusheng Zhu , Andrew Marcus
IPC分类号： C07D235/10 , C07D235/14 , C07D239/91 , C07D249/12 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/04 , C07D413/14 , C07D471/04 , C07D417/02 , A61K31/496 , A61K31/5377 , A61K31/541 , C07D413/02
CPC分类号： C07D401/04 , C07D235/14 , C07D239/91 , C07D249/12 , C07D401/12 , C07D403/12 , C07D405/04 , C07D413/14 , C07D471/04
摘要： Compounds, compositions and methods that are useful in the treatment of inflammatory and immune conditions and diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of a chemokine receptor. The subject methods are useful for the treatment of inflammatory and immunoregulatory disorders and diseases, such as multiple sclerosis, rheumatoid arthritis and type I diabetes.
摘要翻译：本文提供了可用于治疗炎症和免疫疾病和疾病的化合物，组合物和方法。特别地，本发明提供调节趋化因子受体的表达和/或功能的化合物。本发明的方法可用于治疗炎性和免疫调节性疾病和疾病，例如多发性硬化，类风湿性关节炎和I型糖尿病。

73. 发明申请

US20050070083A1 Wafer-level moat structures 有权
标题翻译：晶圆级护城河结构
公开(公告)号：US20050070083A1
公开(公告)日：2005-03-31
申请号：US10672165
申请日：2003-09-26
申请人： Michael Johnson , Peter Elenius , Deok Kim
发明人： Michael Johnson , Peter Elenius , Deok Kim
IPC分类号： H01L20060101 , H01L21/44 , H01L21/60 , H01L21/66 , H01L23/31 , H01L23/485
CPC分类号： H01L24/13 , H01L23/3114 , H01L23/3171 , H01L23/3192 , H01L24/03 , H01L24/05 , H01L2224/0401 , H01L2224/05567 , H01L2224/10126 , H01L2224/10145 , H01L2224/11334 , H01L2224/13007 , H01L2224/13022 , H01L2224/13099 , H01L2224/131 , H01L2924/0002 , H01L2924/01005 , H01L2924/01006 , H01L2924/01013 , H01L2924/0102 , H01L2924/01023 , H01L2924/01024 , H01L2924/01029 , H01L2924/01033 , H01L2924/01057 , H01L2924/01075 , H01L2924/01079 , H01L2924/014 , H01L2924/12042 , H01L2924/14 , H01L2224/05552 , H01L2924/00
摘要： A wafer-level CSP (200) includes at least one die (202) from a wafer. The wafer-level CSP has a plurality of solder ball pads (206), a solder ball (308) at each solder ball pad and a polymer collar (310) around each solder ball. A moat (204) is formed in the surface of a polymer layer (412) disposed on the wafer during manufacturing of the wafer-level CSP. A temporarily liquified residual (502) from the polymer collar, which occurs while the wafer is heated to the reflow temperature of the solder ball, flows from the polymer collar. The moat acts as a barrier to material flow, limiting the distance that the residual spreads while liquified. The residual from the polymer collar remains within a region (314) defined by the moat. A full-depth moat (312) extends completely through the polymer layer. Alternatively, a partial-depth moat (712 and 912) extends partially through the polymer layer. The abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims pursuant to 37 C.F.R. §1.72(b).
摘要翻译：晶片级CSP（200）包括来自晶片的至少一个管芯（202）。晶片级CSP具有多个焊球垫（206），每个焊球垫处的焊球（308）和围绕每个焊球的聚合物环（310）。在晶片级CSP的制造期间，在设置在晶片上的聚合物层（412）的表面中形成护城河（204）。当晶片被加热到焊球的回流温度时，从聚合物套环的临时液化残余物（502）从聚合物套环流出。护城河充当材料流动的障碍，限制了液化时残留物扩散的距离。来自聚合物套环的残余物保留在由护城河限定的区域（314）内。全深的护城河（312）完全延伸穿过聚合物层。或者，部分深度护城河（712和912）部分地延伸穿过聚合物层。提交摘要的理解是，根据37 C.F.R.不会将其用于解释或限制权利要求的范围或含义。 §1.72（b）。

74. 发明申请

US20050069782A1 Forming partial-depth features in polymer film 有权
标题翻译：在聚合物膜中形成部分深度特征
公开(公告)号：US20050069782A1
公开(公告)日：2005-03-31
申请号：US10672201
申请日：2003-09-26
申请人： Peter Elenius , Michael Johnson
发明人： Peter Elenius , Michael Johnson
IPC分类号： G03C5/00 , G03F20060101 , G03F1/14 , G03F9/00 , G21K5/00
CPC分类号： G03F1/50
摘要： A photomask (1900) for producing partial-depth features (712 and 912) in a photo-imageable polymer layer (412) on a wafer of a chip scale package (200) using exposure tools capable of resolving sizes of a critical dimension or larger, has a plurality of chrome lines (2101-2103). Each chrome line has a width (2105) that is less than the critical dimension, and each chrome line of the plurality of chrome lines is spaced apart less than the critical dimension. The plurality of chrome lines produces a single partial-depth feature, such as a via, through part of a thickness of the polymer layer. Alternatively, the photomask has a plurality of chrome circles (2206), each chrome circle having a diameter less than the critical dimension and being spaced apart less than the critical dimension, which produces the partial-depth feature. The photomask may also have chrome of width greater than the critical dimension and spaced from other chrome by a distance greater than the critical dimension, which produces a full-depth feature through the entire thickness of the polymer film. The partial-depth feature and the full-depth feature are produced substantially simultaneously during a single series of photo-imaging steps. By preselecting a size, shape and distance between the chrome, the photomask is capable of inscribing discernable markings on the polymer layer, of changing the thickness of the polymer layer, and of changing an optical property of the surface of the polymer layer. The abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims pursuant to 37 C.F.R. §1.72(b).
摘要翻译：一种光掩模（1900），用于使用能够分辨关键尺寸或更大尺寸的曝光工具在芯片级封装（200）的晶片上的可光成像聚合物层（412）中产生部分深度特征（712和912）具有多条铬线（2101-2103）。每个铬线具有小于临界尺寸的宽度（2105），并且多个铬线的每个铬线间隔开小于临界尺寸。多条铬线通过聚合物层的厚度的一部分产生单一部分深度特征，例如通孔。或者，光掩模具有多个铬圆（2206），每个铬圆的直径小于临界尺寸，并且间隔开小于临界尺寸，产生部分深度特征。光掩模还可以具有大于临界尺寸的宽度的铬，并且与其它铬隔开大于临界尺寸的距离，其通过聚合物膜的整个厚度产生全深度特征。部分深度特征和全深度特征在单个系列的光成像步骤期间基本上同时产生。通过预先选择铬之间的尺寸，形状和距离，光掩模能够在聚合物层上刻划可辨别的标记，改变聚合物层的厚度和改变聚合物层的表面的光学性质。提交摘要的理解是，根据37 C.F.R.不会将其用于解释或限制权利要求的范围或含义。 §1.72（b）。

75. 发明申请

US20050065508A1 Medical device having integral traces and formed electrodes 有权
标题翻译：具有整体痕迹和形成电极的医疗器械
公开(公告)号：US20050065508A1
公开(公告)日：2005-03-24
申请号：US10668843
申请日：2003-09-22
申请人： Michael Johnson , Kirk Honour
发明人： Michael Johnson , Kirk Honour
IPC分类号： A61B5/042 , A61B18/14 , A61N1/05 , A61B18/18 , A61B5/04
CPC分类号： A61B5/6852 , A61B5/0422 , A61B18/1492 , A61B2018/00839 , A61B2562/227 , A61N1/05
摘要： A catheter or lead having electrically conductive traces and external electrical contacts. Each trace may be in electrical connection with one or more external electrical contacts. More specifically, each trace is typically electrically connected to a single contact. The traces and contacts may assist in diagnosis and/or detection of bio-electrical signals emitted by organs, and may transmit such signals to a connector or diagnostic device affixed to the catheter. The external electrical contacts may detect bioelectric energy or may deliver electrical energy to a target site.
摘要翻译：具有导电迹线和外部电触头的导管或导线。每个迹线可以与一个或多个外部电触点电连接。更具体地，每个迹线通常电连接到单个接触。迹线和触点可以有助于诊断和/或检测由器官发射的生物电信号，并且可以将这些信号传输到固定到导管的连接器或诊断装置。外部电触点可以检测生物电能或者可以将电能传递到目标部位。

76. 发明申请

US20050060837A1 SURFACE CLEANER WITH FOLDING UPRIGHT HANDLE AND METHOD OF PACKAGING SAME 失效
标题翻译：带有折叠手柄的表面清洁器及其包装方法
公开(公告)号：US20050060837A1
公开(公告)日：2005-03-24
申请号：US10707392
申请日：2003-12-10
申请人： Michael Johnson , Kevin Breuker
发明人： Michael Johnson , Kevin Breuker
IPC分类号： A47L9/00 , A47L9/32 , A47L9/10 , A47L9/20
CPC分类号： A47L9/0009 , A47L9/325
摘要： A portable surface cleaner comprises a cleaner base and an upright handle assembly pivotably connected to the cleaner base. A lower portion of the handle comprises an upper, pivot section and a lower, base section joined by a horizontal pivot axis so that the pivot section can rotate downwardly to fold against the base section to form a compact configuration for packaging, shipment, and display and pivot upwardly for assembly of the upright handle assembly prior to use.
摘要翻译：便携式表面清洁器包括清洁器基座和可枢转地连接到清洁器基座的直立手柄组件。手柄的下部包括上部枢转部分和下部基部，其由水平枢转轴线连接，使得枢转部分可向下旋转以折叠抵靠基部以形成用于包装，装运和展示的紧凑构型并且在使用之前向上枢转以组装直立手柄组件。

77. 发明申请

US20050043381A1 Aminopyrazole compounds 审中-公开
标题翻译：氨基吡唑化合物
公开(公告)号：US20050043381A1
公开(公告)日：2005-02-24
申请号：US10897849
申请日：2004-07-22
申请人： Michael Johnson , Min Teng , Jinjiang Zhu
发明人： Michael Johnson , Min Teng , Jinjiang Zhu
IPC分类号： A61P35/00 , C07D231/38 , C07D401/12 , C07D403/12 , C07D417/12 , A61K31/425 , C07D275/02
CPC分类号： C04B35/632 , C07D231/38 , C07D401/12 , C07D403/12 , C07D417/12
摘要： Described herein are aminopyrazole compounds of formula I: wherein R1, R2, L and Ar are as defined in the specification. Such compounds are capable of modulating the activity of a checkpoint kinase and methods for utilizing such modulation to treat cell proliferative disorders. Also described are pharmaceutical compositions containing such compounds. Also described are the therapeutic or prophylactic use of such compounds and compositions, and methods of treating cancer as well as other diseases associated with unwanted cellular proliferation, by administering effective amounts of such compounds in combination with anti-neoplastic agents.
摘要翻译：本文描述的是式I的氨基吡唑化合物：其中R 1，R 2，L和Ar如说明书中所定义。这些化合物能够调节检查点激酶的活性和利用这种调节来治疗细胞增殖性疾病的方法。还描述了含有这些化合物的药物组合物。还描述了这样的化合物和组合物的治疗或预防用途，以及通过与抗肿瘤剂组合施用有效量的这种化合物来治疗癌症以及与不想要的细胞增殖相关的其它疾病的方法。

78. 发明申请

US20050027646A1 METHOD AND SYSTEM FOR FINANCING ACQUISITION OF VEHICLES 有权
标题翻译：资助车辆收购的方法和系统
公开(公告)号：US20050027646A1
公开(公告)日：2005-02-03
申请号：US10604536
申请日：2003-07-29
申请人： Christopher Hall , Bradley Gayton , Bernie Johnson , John Polizzi , Michael Johnson
发明人： Christopher Hall , Bradley Gayton , Bernie Johnson , John Polizzi , Michael Johnson
IPC分类号： G06F17/60
CPC分类号： G06Q40/02 , G06Q40/00 , G06Q40/025 , G06Q40/04 , G06Q40/06
摘要： In one embodiment of the present invention, a method for financing acquisition of a vehicle is disclosed. The method comprises receiving a future interest in a vehicle in consideration for a future interest price upon transfer of a legal title in the vehicle in consideration for a legal title price.
摘要翻译：在本发明的一个实施例中，公开了一种用于融资车辆购置的方法。该方法包括在考虑合法所有权价格的车辆中转移合法所有权后，考虑到未来利息价格来考虑车辆的未来利益。

79. 发明授权

US06667606B2 Power regulation and thermal management circuit 有权
标题翻译：电源调节和热管理电路
公开(公告)号：US06667606B2
公开(公告)日：2003-12-23
申请号：US10077355
申请日：2002-02-15
申请人： John Wendell Oglesbee , Chris Hanchana Thongsouk , Robert Michael Johnson, Jr.
发明人： John Wendell Oglesbee , Chris Hanchana Thongsouk , Robert Michael Johnson, Jr.
IPC分类号： G05F140
CPC分类号： G05F1/565 , H02M3/157
摘要： This invention provides a means of protecting power dissipating pass elements from exceeding their predetermined thermal limits. In one preferred embodiment, the circuit protects a pass element in a battery charging circuit from exceeding its threshold junction temperature by predicting temperature based upon the voltage across the pass element and the current flowing through it. From this predicted temperature, current is reduced to provide charging of a battery at a constant power. The circuit includes a voltage sensing circuit and a plurality of comparators for selecting a predetermined current based upon the output of the voltage sensing circuit. The circuit provides a piecewise linear approximation of proper pass element voltage and current values to maintain a suitable threshold junction temperature.
摘要翻译：本发明提供了一种保护功率耗散通过元件超过其预定热限制的方法。在一个优选实施例中，电路通过基于通过元件上的电压和流过它的电流预测温度来保护电池充电电路中的通过元件超过其阈值结温度。根据该预测温度，降低电流以使电池以恒定的功率进行充电。电路包括电压检测电路和用于基于电压检测电路的输出来选择预定电流的多个比较器。该电路提供适当的通过元件电压和电流值的分段线性近似，以保持合适的阈值结温。

80. 发明授权

US06588266B2 Monitoring of downhole parameters and tools utilizing fiber optics 有权
公开(公告)号：US06588266B2
公开(公告)日：2003-07-08
申请号：US09872591
申请日：2001-06-01
申请人： Paulo Tubel , Brian Bidigare , Michael Johnson , John Harrell , Benn Voll
发明人： Paulo Tubel , Brian Bidigare , Michael Johnson , John Harrell , Benn Voll
IPC分类号： E21B4710
CPC分类号： G01V11/002 , E21B23/03 , E21B33/1275 , E21B37/06 , E21B41/0035 , E21B41/02 , E21B43/12 , E21B43/122 , E21B43/123 , E21B43/16 , E21B43/20 , E21B43/25 , E21B43/26 , E21B47/00 , E21B47/011 , E21B47/06 , E21B47/065 , E21B47/10 , E21B47/101 , E21B47/1015 , E21B47/102 , E21B47/123 , E21B49/00 , E21B49/006 , E21B49/008 , E21B49/08 , G01D5/268 , G01N21/31 , G01V1/40 , G01V1/42 , G01V1/46 , G01V1/52 , G01V7/08 , G01V7/16 , G01V8/02 , G01V11/00 , G01V2210/6163 , G01V2210/6167
摘要： The present invention provides systems utilizing fiber optics for monitoring downhole parameters and the operation and conditions of downhole tools. In one system fiber optics sensors are placed in the wellbore to make distributed measurements for determining the fluid parameters including temperature, pressure, fluid flow, fluid constituents and chemical properties. Optical spectrometric sensors are employed for monitoring chemical properties in the wellbore and at the surface for chemical injection systems. Fiber optic sensors are utilized to determine formation properties including resistivity and acoustic properties compensated for temperature effects. Fiber optic sensors are used to monitor the operation and condition of downhole devices including electrical submersible pumps and flow control devices. In one embodiment, a common fluid line is used to monitor downhole parameters and to operate hydraulically-operated devices. Fiber optic sensors are also deployed to monitor the physical condition of power lines supplying high electric power to downhole equipment. A light cell disposed downhole is used to generate electric power in the wellbore, which is used to charge batteries.

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