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71. 发明申请

US20140302777A1 2 Channel Switched Loop-thru Microwave Switch 审中-公开
标题翻译： 2通道开关环路微波开关
公开(公告)号：US20140302777A1
公开(公告)日：2014-10-09
申请号：US13858069
申请日：2013-04-07
申请人： Mark Scott Logue
发明人： Mark Scott Logue
IPC分类号： H04B7/15
CPC分类号： H04B7/15 , H01P1/15
摘要： A five port two channel switch, with switched loop-thru inputs. The switch has DC to 5.5 GHz bandwidth, flat frequency response, excellent transient response, high isolation between channels, and 50 ohm input and output impedance when the channel is either ON or OFF. The input to a unused channel may also be used in another circuit given the loop-thru option of the switch.
摘要翻译：一个五端口双通道开关，带有交流环路输入。当通道为ON或OFF时，该开关具有DC至5.5 GHz带宽，平坦的频率响应，出色的瞬态响应，通道之间的高隔离度以及50欧姆的输入和输出阻抗。给定交换机的环通选项，也可以在另一个电路中使用未使用信道的输入。

72. 发明授权

US08652473B2 Antibodies to EGF receptor epitope peptides and uses thereof 有权
标题翻译： EGF受体表位肽的抗体及其用途
公开(公告)号：US08652473B2
公开(公告)日：2014-02-18
申请号：US12657919
申请日：2010-01-29
申请人： Terrance Grant Johns , Andrew Mark Scott , Antony Wilks Burgess , Lloyd J. Old , Timothy E. Adams , K. Dane Wittrup , Ginger Chao , Peter Anthony Hoyne
发明人： Terrance Grant Johns , Andrew Mark Scott , Antony Wilks Burgess , Lloyd J. Old , Timothy E. Adams , K. Dane Wittrup , Ginger Chao , Peter Anthony Hoyne
IPC分类号： A61K39/395 , C12P21/08 , C07K16/00
CPC分类号： C07K14/71 , A61K39/00
摘要： The present invention relates generally to growth factor receptor epitope peptides, particularly EGF family receptor epitope peptides. The invention also relates to the use of the receptor peptides in generating antibodies which have anti-tumor or anti-cancer activity or in stimulating an immunological response. The invention further relates to antibodies specifically directed against the receptor peptides. Methods for generating an immune response and for treatment of tumors and cancer are also provided.
摘要翻译：本发明一般涉及生长因子受体表位肽，特别是EGF家族受体表位肽。本发明还涉及受体肽在产生具有抗肿瘤或抗癌活性或刺激免疫应答的抗体中的用途。本发明还涉及特异性针对受体肽的抗体。还提供了产生免疫应答和治疗肿瘤和癌症的方法。

73. 发明授权

US08399234B2 Perhydrolase variant providing improved specific activity 失效
公开(公告)号：US08399234B2
公开(公告)日：2013-03-19
申请号：US13328364
申请日：2011-12-16
申请人： Robert DiCosimo , Mark Scott Payne , John Edward Gavagan
发明人： Robert DiCosimo , Mark Scott Payne , John Edward Gavagan
IPC分类号： C12N9/18 , C12P7/40 , A61L9/00
CPC分类号： C11D3/2093 , A61L2/186 , C11D3/38627 , C11D3/38636 , C11D3/3942 , C11D3/3947 , C12N9/18 , C12P7/40 , C12P7/54 , C12Y301/01
摘要： An acetyl xylan esterase variant having perhydrolytic activity is provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. More specifically, a Thermotoga maritima acetyl xylan esterase gene was modified using error-prone PCR and site-directed mutagenesis to create an enzyme catalyst characterized by an increase in specific activity. The variant acetyl xylan esterase may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, and paper pulp processing applications.

74. 发明授权

US08395451B2 Low 1/f noise high-frequency broadband amplifier (DC-12 GHz) 失效
标题翻译：低1 / f噪声高频宽带放大器（DC-12GHz）
公开(公告)号：US08395451B2
公开(公告)日：2013-03-12
申请号：US12931027
申请日：2011-01-20
申请人： Mark Scott Logue
发明人： Mark Scott Logue
IPC分类号： H03F3/16
CPC分类号： H03F1/226 , H03F1/26 , H03F1/3223 , H03F3/1935 , H03F2200/36
摘要： A N-Channel HJ-FET cascode amplifier, with a High Frequency NPN Transistor differential error amplifier, having low 1/f noise, a DC to 12 GHz bandwidth, flat frequency response, excellent transient response, high linearity, and low input and output VSWR over a wide frequency range.
摘要翻译：具有高频NPN晶体管差分放大器的N沟道HJ-FET共源共栅放大器，具有低1 / f噪声，DC至12 GHz带宽，平坦的频率响应，出色的瞬态响应，高线性度和低输入和输出 VSWR在宽频率范围内。

75. 发明授权

US08389260B2 Perhydrolase variant providing improved specific activity 失效
标题翻译：过水解酶变体提供改善的比活性
公开(公告)号：US08389260B2
公开(公告)日：2013-03-05
申请号：US13328418
申请日：2011-12-16
申请人： Robert DiCosimo , Mark Scott Payne , John Edward Gavagan
发明人： Robert DiCosimo , Mark Scott Payne , John Edward Gavagan
IPC分类号： C12N9/18 , C12P7/40 , A61L9/00
CPC分类号： C12N9/18 , C12Y301/01072
摘要： An acetyl xylan esterase variant having perhydrolytic activity is provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. More specifically, a Thermotoga maritime acetyl xylan esterase gene was modified using error-prone PCR and site-directed mutagenesis to create an enzyme catalyst characterized by an increase in specific activity. The variant acetyl xylan esterase may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, and paper pulp processing applications.
摘要翻译：提供具有过水解活性的乙酰木聚糖酯酶变体，用于从羧酸酯和过氧源产生过氧羧酸。更具体地，使用易错PCR和定点诱变来修饰Thermotoga海洋乙酰木聚糖酯酶基因，以产生特征在于比活性增加的酶催化剂。变体乙酰木聚糖酯酶可用于制备适用于各种用途的过氧羧酸，例如清洁，消毒，消毒，漂白，木浆加工和纸浆加工应用。

76. 发明授权

US08389258B2 Perhydrolase variant providing improved specific activity 失效
公开(公告)号：US08389258B2
公开(公告)日：2013-03-05
申请号：US13328336
申请日：2011-12-16
申请人： Robert DiCosimo , Mark Scott Payne , John Edward Gavagan
发明人： Robert DiCosimo , Mark Scott Payne , John Edward Gavagan
IPC分类号： C12N9/18 , C12P7/40 , A61L9/00
CPC分类号： C11D3/38636 , C11D3/3945 , C12N9/18 , C12P7/40 , C12Y301/01072
摘要： An acetyl xylan esterase variant having perhydrolytic activity is provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. More specifically, a Thermotoga maritima acetyl xylan esterase gene was modified using error-prone PCR and site-directed mutagenesis to create an enzyme catalyst characterized by an increase in specific activity. The variant acetyl xylan esterase may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, and paper pulp processing applications.

77. 发明授权

US08389255B2 Perhydrolase providing improved specific activity 失效
标题翻译：过水解酶提供更好的比活性
公开(公告)号：US08389255B2
公开(公告)日：2013-03-05
申请号：US13070135
申请日：2011-03-23
申请人： Robert Dicosimo , John Edward Gavagan , Mark Scott Payne
发明人： Robert Dicosimo , John Edward Gavagan , Mark Scott Payne
IPC分类号： C12N9/18
CPC分类号： C12N9/18 , C11D3/38636 , C12P7/40 , C12P7/54
摘要： An acetyl xylan esterase variant having perhydrolytic activity is provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. More specifically, a Thermotoga maritima acetyl xylan esterase gene was modified using error-prone PCR and site-directed mutagenesis to create an enzyme catalyst characterized by an increase in specific activity. The variant acetyl xylan esterase may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, and paper pulp processing applications.
摘要翻译：提供具有过水解活性的乙酰木聚糖酯酶变体，用于从羧酸酯和过氧源产生过氧羧酸。更具体地，使用易错PCR和定点诱变来修饰热转录海马乙酰木聚糖酯酶基因，以产生特征在于比活性增加的酶催化剂。变体乙酰木聚糖酯酶可用于制备适用于各种用途的过氧羧酸，例如清洁，消毒，消毒，漂白，木浆加工和纸浆加工应用。

78. 发明授权

US08343764B2 Genes encoding glutamine synthetase and uses for plant improvement 有权
标题翻译：编码谷氨酰胺合成酶的基因和用于植物改良的基因
公开(公告)号：US08343764B2
公开(公告)日：2013-01-01
申请号：US12459621
申请日：2009-07-02
申请人： Mark Scott Abad , Marie A. Coffin , Barry S. Goldman
发明人： Mark Scott Abad , Marie A. Coffin , Barry S. Goldman
IPC分类号： C12N15/82 , A01H5/00 , A01H5/10 , A01H1/00
CPC分类号： C12N15/8273 , C07K14/415 , C12N15/8241 , C12N15/8243 , C12N15/8247 , C12N15/8251 , C12N15/8261 , Y02A40/146
摘要： Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA in the nucleus of cells of the seed where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. The present invention provides recombinant DNA molecules for expression of a protein, including a recombinant DNA molecule for expression of a glutamine synthetase.
摘要翻译：具有改善性状的作物的转基因种子通过在种子细胞核中改良重组DNA来提供，其中与对照植物相比，从这种转基因种子生长的植物表现出一种或多种改良的性状。本发明提供用于表达蛋白质的重组DNA分子，包括用于表达谷氨酰胺合成酶的重组DNA分子。

79. 发明授权

US08296433B2 Virtualization method and apparatus for integrating enterprise applications 失效
标题翻译：用于集成企业应用程序的虚拟化方法和设备
公开(公告)号：US08296433B2
公开(公告)日：2012-10-23
申请号：US11749124
申请日：2007-05-15
申请人： Luis F. Stevens , Robert J. Petri , George Mark Scott
发明人： Luis F. Stevens , Robert J. Petri , George Mark Scott
IPC分类号： G06F15/173
CPC分类号： G06F9/5072 , H04L67/10 , H04L69/08 , H04L69/32 , H04L69/329
摘要： A method and apparatus is provided for integrating an application into a network of computing resources. Applications using this integration have a virtualized access to one or more computing resources associated with the network. Virtualization is generally assured through at least one network connection between the virtual layer and the native network. Together, the virtual access is used to generate a virtual application network capable of providing the application access to the network of computing resources. The application is created into an orchestration of operations to manipulate the one or more computing resources according to a business process. As needed, the application and orchestration can be further partitioning into components to be distributed and executed over the virtual application network using the virtualized access.
摘要翻译：提供了一种用于将应用集成到计算资源的网络中的方法和装置。使用此集成的应用程序对与网络相关联的一个或多个计算资源进行虚拟访问。虚拟化通常通过虚拟层和本机网络之间的至少一个网络连接得到保证。一起，虚拟访问用于生成能够提供应用程序访问计算资源网络的虚拟应用程序网络。该应用被创建为根据业务流程来操纵一个或多个计算资源的操作的编排。根据需要，应用程序和业务流程可以进一步划分为要使用虚拟化访问在虚拟应用程序网络上分发和执行的组件。

80. 发明申请

US20120188021A1 Low 1/f noise high-frequency broadband amplifier (DC-12 GHz) 失效
标题翻译：低1 / f噪声高频宽带放大器（DC-12 GHz）
公开(公告)号：US20120188021A1
公开(公告)日：2012-07-26
申请号：US12931027
申请日：2011-01-20
申请人： Mark Scott Logue
发明人： Mark Scott Logue
IPC分类号： H03F3/04 , H03F1/22
CPC分类号： H03F1/226 , H03F1/26 , H03F1/3223 , H03F3/1935 , H03F2200/36
摘要： A N-Channel HJ-FET cascode amplifier, with a High Frequency NPN Transistor differential error amplifier, having low 1/f noise, a DC to 12 GHz bandwidth, flat frequency response, excellent transient response, high linearity, and low input and output VSWR over a wide frequency range.
摘要翻译：具有高频NPN晶体管差分放大器的N沟道HJ-FET共源共栅放大器，具有低1 / f噪声，DC至12 GHz带宽，平坦的频率响应，出色的瞬态响应，高线性度和低输入和输出 VSWR在宽频率范围内。

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