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71. 发明授权

US06315717B1 Surgical instruments for stabilizing the beating heart during coronary artery bypass graft surgery 有权
标题翻译：用于在冠状动脉旁路移植手术期间稳定跳动心脏的手术器械
公开(公告)号：US06315717B1
公开(公告)日：2001-11-13
申请号：US09550447
申请日：2000-04-17
申请人： Federico J. Benetti , Charles S. Taylor , Ivan Sepetka , Amr Salahieh , Robert C. Glines , William N. Aldrich , Brent Regan , John J. Frantzen
发明人： Federico J. Benetti , Charles S. Taylor , Ivan Sepetka , Amr Salahieh , Robert C. Glines , William N. Aldrich , Brent Regan , John J. Frantzen
IPC分类号： A61B132
CPC分类号： A61B17/0218 , A61B17/00234 , A61B17/02 , A61B17/0206 , A61B17/0642 , A61B17/12 , A61B17/3421 , A61B17/3423 , A61B90/00 , A61B2017/00243 , A61B2017/00557 , A61B2017/00703 , A61B2017/00858 , A61B2017/0243 , A61B2017/1139 , A61B2017/2825 , A61B2017/2913 , A61B2017/2929 , A61B2017/306 , A61B2017/349
摘要： Methods and devices used to stabilize a beating heart during a surgical procedure on the heart are disclosed. The stabilizing device is introduced through an opening through the chest and brought into contact with the beating heart, and by exerting a stabilizing force on the device, the motion of the heart caused by the contractions of the heart muscles is effectively eliminated. Accordingly, the heart is stabilized and movement of the site of the surgery is minimized. Typically, in separate steps, a surgeon contacts the heart with the stabilizing device, assesses the degree of movement of the anastomosis site, and exerts a force with a stabilizing device such that the contractions of the beating heart causes only minimal excess motion at the surgery site. The stabilizing device may be attached to a rigid support or may be attached to a semi-rigid support which is rendered motionless mechanically, chemically or by human intervention.
摘要翻译：公开了用于在外科手术中心脏稳定跳动心脏的方法和装置。稳定装置通过穿过胸部的开口被引入与打心的心脏接触，并且通过在装置上施加稳定力，有效地消除了由心脏肌肉收缩引起的心脏运动。因此，心脏稳定并且手术部位的运动被最小化。通常，在单独的步骤中，外科医生将心脏与稳定装置接触，评估吻合部位的移动程度，并用稳定装置施加力，使得跳动心脏的收缩在手术时仅引起极小的过度运动现场。稳定装置可以附接到刚性支撑件或者可以附接到半刚性支撑件，其通过机械地，化学地或通过人为干预使其静止。

72. 发明授权

US06190311B1 Retractor and instrument platform for a less invasive cardiovascular surgical procedure 失效
标题翻译：牵引器和仪器平台，用于低侵入性心血管外科手术
公开(公告)号：US06190311B1
公开(公告)日：2001-02-20
申请号：US08850150
申请日：1997-05-02
申请人： Robert C. Glines , Ivan Sepetka
发明人： Robert C. Glines , Ivan Sepetka
IPC分类号： A61B130
CPC分类号： A61B17/0293 , A61B17/0206 , A61B2017/0237
摘要： An instrument platform and retractor, for holding and organizing cannulas, instruments and sutures during a surgical procedure, wherein the instrument platform has a platform body which is mountable to the retractor and includes a central opening and cannula notches formed therein adjacent to the central opening for securing cannulas during a surgical procedure. The platform body also includes suture grips and instrument mounts for securing surgical instruments and sutures during a surgical procedure. The retractor includes a pair of blades and a spreader mechanism detachably mounted to blade arms.
摘要翻译：一种用于在手术过程中保持和组织插管，器械和缝合线的仪器平台和牵开器，其中所述仪器平台具有可安装到所述牵开器的平台体，并且包括邻近所述中心开口形成的中心开口和套管凹口，在外科手术过程中确保插管。平台体还包括缝合夹和仪器座，用于在手术过程中固定手术器械和缝合线。牵开器包括一对刀片和可拆卸地安装到刀臂上的吊架机构。

73. 发明授权

US5944736A Access platform for internal mammary dissection 失效
公开(公告)号：US5944736A
公开(公告)日：1999-08-31
申请号：US903516
申请日：1997-07-30
申请人： Charles S. Taylor , William N. Aldrich , Federico J. Benetti , Richard S. Ginn , Dwight P. Morejohn , Brent Regan , Eugene E. Reis , Ivan Sepetka , William F. Witt
发明人： Charles S. Taylor , William N. Aldrich , Federico J. Benetti , Richard S. Ginn , Dwight P. Morejohn , Brent Regan , Eugene E. Reis , Ivan Sepetka , William F. Witt
IPC分类号： A61B17/02 , A61B17/34 , A61B19/00
CPC分类号： A61B17/3423 , A61B17/0206 , A61B90/50 , A61B17/025 , A61B17/3476 , A61B2017/349
摘要： An access platform having a first and a second blade interconnected to a spreader member that laterally drives the blades apart or together and a sternal pad interconnected to a blade. The superior blade is pivotally coupled to the spreader member such that it naturally rises as the blades are separated. Alternatively, a vertical displacement member is operably interconnected to a blade and the spreader member and is used to vertically displace the interconnected superior blade and, thus, increase a surgeon's working space and visual access for the dissection of an internal mammary artery. A tissue retractor is interconnected to the blades to draw the soft tissue around an incision away from the surgeon's working area.

74. 发明授权

US5871496A Surgical instrument for facilitating the detachment of an artery and the like 失效
公开(公告)号：US5871496A
公开(公告)日：1999-02-16
申请号：US835675
申请日：1997-04-10
申请人： Richard S. Ginn , Hani Shennib , Charles S. Taylor , Ivan Sepetka
发明人： Richard S. Ginn , Hani Shennib , Charles S. Taylor , Ivan Sepetka
IPC分类号： A61B17/00 , A61B17/02 , A61B17/28 , A61B17/32 , A61B18/14
CPC分类号： A61B17/00008 , A61B17/02 , A61B17/00234 , A61B17/320016 , A61B2017/00867 , A61B2017/00969 , A61B2017/2905 , A61B2017/2927 , A61B2018/00916 , A61B2018/1253 , A61B2018/1407 , A61B2018/1435
摘要： A surgical instrument is configured to aid in performing a procedure of detaching an internal mammary artery (IMA) and the like, from the connecting tissues and side branch vessels which surround the artery in its native location, wherein the detaching procedure is preliminary to the performing of a coronary artery bypass grafting procedure and wherein the IMA is detached via a minimally invasive thoracotomy. To this end, an elongated slender rod includes a handle at its proximal end and an artery engaging loop, arc, fork configuration, or hook at its distal working end. Embodiments may incorporate electrosurgical capability or electrical insulation. A surgeon thus has means for harvesting an intact and undamaged graft vessel from its native location through a minimally invasive incision with enhanced speed, visibility, and freedom of motion.

75. 发明授权

US5776154A Surgical instruments for making precise incisions in a cardiac vessel 失效
标题翻译：用于在心脏血管中进行精确切口的手术器械
公开(公告)号：US5776154A
公开(公告)日：1998-07-07
申请号：US603329
申请日：1996-02-20
申请人： Charles S. Taylor , John J. Frantzen , Ivan Sepetka
发明人： Charles S. Taylor , John J. Frantzen , Ivan Sepetka
IPC分类号： A61B17/00 , A61B17/28 , A61B17/32
CPC分类号： A61B17/32 , A61B17/320016 , A61B2017/00243 , A61B2017/00703 , A61B2017/00778 , A61B2017/2925 , A61B2017/320052
摘要： Surgical instruments and methods for making substantially linear incisions, especially through the wall of vessels, such as arteries, specifically designed for coronary artery bypass graft procedures (CABG) on the beating heart. The invention is particularly useful to create the incision in the artery to which a bypass graft is sewn, typically the left anterior descending artery (LAD). The instruments allow incisions to be rapidly made, precisely measured, and cleanly formed so that a bypass graft can be rapidly sewn in place, without undue trauma to surrounding tissue and excessive loss of blood. In one embodiment, a hand-held instrument has a cutting edge formed on the interior edge of a curved blade fixed near the end of the instrument. The tip of the blade has a point for penetrating the vessel wall which may have several alternate shapes to facilitate penetration of the vessel wall while minimizing trauma to the surrounding tissue. In another embodiment the hand-held instrument includes a moveable member which creates an incision by engaging a cutting blade against a stop, cutting tissue therebetween, the stop including a pointed tip similar to the previous embodiment. In another embodiment, the instrument features a motion-canceling member which compensates for the movement of the target surface to be incised. This embodiment has a cutting blade which is manipulated from a handle which is isolated from the movement of the tissue containing or proximate to the target of the incision.
摘要翻译：用于进行基本上线性切口的手术器械和方法，特别是通过专门设计用于搏动心脏上的冠状动脉旁路移植手术（CABG）的诸如动脉的血管壁。本发明特别有用于在缝合旁路移植物的动脉中产生切口，通常为左前降支动脉（LAD）。这些仪器允许快速地进行切割，精确测量和清洁地形成，使得旁路移植物可以快速缝合就位，而不会对周围组织造成过度的创伤和过度的血液损失。在一个实施例中，手持式仪器具有形成在靠近仪器端部的弯曲刀片的内边缘上的切割刃。叶片的尖端具有穿透血管壁的点，该点可以具有若干替代形状，以促进血管壁的穿透，同时最小化对周围组织的创伤。在另一个实施例中，手持式仪器包括可移动构件，其通过将切割刀片接合止挡件而形成切口，在其间切割组织，止动件包括类似于先前实施例的尖端。在另一个实施例中，仪器具有补偿待切割的目标表面的移动的运动消除构件。该实施例具有从手柄操纵的切割刀片，该手柄与包含或接近切口目标的组织的运动隔离。

76. 发明授权

US5730757A Access platform for internal mammary dissection 失效
标题翻译：内部乳腺切开手术平台
公开(公告)号：US5730757A
公开(公告)日：1998-03-24
申请号：US604161
申请日：1996-02-20
申请人： Federico J. Benetti , Charles S. Taylor , William N. Aldrich , Ivan Sepetka , Robert G. Matheny , Eugene E. Reis , Brent Regan , Richard M. Ferrari
发明人： Federico J. Benetti , Charles S. Taylor , William N. Aldrich , Ivan Sepetka , Robert G. Matheny , Eugene E. Reis , Brent Regan , Richard M. Ferrari
IPC分类号： A61B17/02 , A61B17/34 , A61B19/00
CPC分类号： A61B17/3423 , A61B17/0206 , A61B90/50 , A61B17/025 , A61B2017/3427 , A61B2017/349
摘要： An access platform having a first and a second blade interconnected to a spreader member that laterally drives the blades apart or together and support pads interconnected to the first blade. A torsional member is operably interconnected to the first blade and the spreader member and is used to vertically displace the first blade in either direction and, thus, increase a surgeon's working space and visual access for the dissection of an internal mammary artery. A tissue retractor interconnected to the blades is used to draw the soft tissue around an incision away from the surgeon's working area.
摘要翻译：一种进入平台，其具有与扩展构件相互连接的第一和第二叶片，所述第一和第二叶片横向地驱动叶片彼此分离或一起，并且支撑与第一叶片互连的垫。扭转构件可操作地连接到第一叶片和展开构件，并且用于沿任一方向垂直地移位第一叶片，并且因此增加外科医生的工作空间和用于内部乳房动脉解剖的视觉进入。使用与叶片互连的组织牵开器将软组织围绕切口远离外科医生的工作区域。

77. 发明授权

US5429605A Microballoon catheter 失效
标题翻译：微血管导管
公开(公告)号：US5429605A
公开(公告)日：1995-07-04
申请号：US188382
申请日：1994-01-26
申请人： Richling: Bernd , Ivan Sepetka , Uriel H. Chee , Liem Ho , Phong Pham
发明人： Richling: Bernd , Ivan Sepetka , Uriel H. Chee , Liem Ho , Phong Pham
IPC分类号： A61M25/00 , A61F2/958 , A61M29/00
CPC分类号： A61M25/1006 , A61M25/0054 , A61M25/1025
摘要： This invention is a microballoon tipped catheter. The catheter has a shaft which is of varying flexibility with the most flexible portion towards the distal tip. The balloon, located near the distal tip of the catheter, is typically of an elastic material, is quite flexible in its own right when deflated, and is quite small. The catheter shaft has a main lumen extending from the proximal end to the distal end so to allow the use of a guidewire in placing the catheter's distal tip in remote regions of the vasculature and for delivery of drugs, diagnostics, and other biologics to those regions. The catheter shaft has a wall that desirably is of a multilayer construction. The wall preferably includes an independent lumen, which may be formed from a small diameter tubing that is placed between layers of the wall, for the inflation and deflation of the microballoon. The inflation lumen proceeds from the proximal end of the catheter and terminates near the distal end of the catheter but within the microballoon. This catheter is especially useful in treating disease within the high pressure vessels of the brain with drugs or other therapeutic agents and permits temporary blockage of blood flow and thereby allow better absorption of those active agents.
摘要翻译：本发明是一种微气囊导管。该导管具有一个具有不同柔性的轴，朝向远侧末端具有最柔韧的部分。位于导管远侧末端附近的气囊通常是弹性材料，当放气时本身是相当灵活的，并且相当小。导管轴具有从近端延伸到远端的主腔，以便允许使用导丝将导管的远侧末端放置在脉管系统的偏远区域中并用于将药物，诊断和其它生物制剂递送至那些区域。导管轴具有期望地具有多层结构的壁。壁优选地包括独立的内腔，其可以由放置在壁的层之间的小直径管形成，用于微气泡的充气和放气。膨胀腔从导管的近端延伸，并在导管的远端附近终止，但在微球内。该导管特别适用于用药物或其它治疗剂治疗脑高压血管内的疾病，并允许临时阻塞血流，从而允许更好地吸收那些活性剂。

78. 发明授权

US5312356A Catheter with low-friction distal segment 失效
标题翻译：导管与低摩擦远端段
公开(公告)号：US5312356A
公开(公告)日：1994-05-17
申请号：US527200
申请日：1990-05-22
申请人： Erik T. Engelson , Ivan Sepetka
发明人： Erik T. Engelson , Ivan Sepetka
IPC分类号： A61M25/00 , A61M25/01 , A61M25/09 , A61M5/178 , A61M5/32
CPC分类号： A61M25/01 , A61M25/0052 , A61M25/0054 , A61M2025/0046 , A61M2025/0047 , A61M2025/09091 , A61M25/0012 , A61M25/0053 , A61M25/09
摘要： A catheter for accessing a target site along a tortuous, small-vessel pathway. The catheter includes a flexible distal segment which is composed of a flexible polymer tube and a low-friction internal tubular surface. The surface allows the catheter to be advanced over sharp bends and small-diameter loops in a guidewire, in advancing the catheter along a small-vessel pathway. Various embodiments of the catheter are disclosed wherein the internal tubular surface of a distal portion of the catheter include a variety of different constructions and are comprised of a variety of different materials so as to best avoid the jamming, sticking or locking of the distal end or any part of the guidewire against the surface. Braided sleeve-like constructions, surfaces embedded with a plurality of small particles and surfaces comprised of various anti-friction materials are used in order to obtain the object of the invention.
摘要翻译：用于沿着曲折的小血管途径进入目标部位的导管。导管包括柔性远端段，其由柔性聚合物管和低摩擦内部管状表面组成。表面允许导管在导丝中的尖锐弯曲和小直径环上前进，沿着小血管通路推进导管。公开了导管的各种实施例，其中导管的远端部分的内部管状表面包括各种不同的结构，并且由各种不同的材料组成，以便最好地避免远端的卡住，粘附或锁定导丝的任何部分抵靠表面。为了获得本发明的目的，使用编织的套筒状结构，嵌入多个小颗粒的表面和由各种抗摩擦材料组成的表面。

79. 发明授权

US4832047A Guide wire device 失效
标题翻译：导线装置
公开(公告)号：US4832047A
公开(公告)日：1989-05-23
申请号：US132924
申请日：1987-12-15
申请人： Ivan Sepetka , Erik T. Engelson
发明人： Ivan Sepetka , Erik T. Engelson
IPC分类号： A61B17/00 , A61B17/22
CPC分类号： A61M25/09033 , A61B2017/00526 , A61B2017/22001 , A61M2025/09175
摘要： A guide wire formed with a distal tapered segment and having a distal-end coil carried over a portion of the tapered segment. The strand forming the helical wrappings of the coil is reduced in thickness in the region of proximal attachment to the wire, to reduce the difference in diameter between the wire and the coil. Also disclosed is a method of producing the coil.
摘要翻译：导丝，其形成有远端锥形段，并且具有承载在锥形段的一部分上的远端线圈。形成线圈的螺旋形包装的线材在近端连接到线材的区域中的厚度减小，以减少线材和线圈之间的直径差。还公开了一种制造线圈的方法。

80. 发明授权

US08298257B2 Systems, methods and devices for removing obstructions from a blood vessel 有权
公开(公告)号：US08298257B2
公开(公告)日：2012-10-30
申请号：US11250190
申请日：2005-10-13
申请人： Ivan Sepetka , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Tran Ngo
发明人： Ivan Sepetka , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Tran Ngo
IPC分类号： A61M29/00
CPC分类号： A61B17/221 , A61B17/22 , A61B17/22031 , A61B2017/00336 , A61B2017/22034 , A61B2017/22094 , A61B2017/2212 , A61B2017/2215 , A61B2017/2217 , A61F2/013 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0091 , A61F2250/0065
摘要： Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction.

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