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61. 发明申请

US20130267709A1 Bisamineazaallylic Ligands And Their Use In Atomic Layer Deposition Methods 审中-公开
标题翻译：双胺化合物配体及其在原子层沉积方法中的应用
公开(公告)号：US20130267709A1
公开(公告)日：2013-10-10
申请号：US13908359
申请日：2013-06-03
申请人： David Thompson , Jeffrey W. Anthis
发明人： David Thompson , Jeffrey W. Anthis
IPC分类号： C07F15/00 , C07F11/00 , C07C211/13 , C07F9/00 , C07F1/10 , C07F7/28 , C07F13/00
CPC分类号： C07F15/00 , C07C211/13 , C07F1/10 , C07F1/12 , C07F7/28 , C07F9/00 , C07F11/00 , C07F11/005 , C07F13/00 , C07F13/005 , C07F15/004 , C07F15/0053 , C07F15/0066 , C07F15/008 , C07F15/0093 , C23C16/18 , C23C16/45553
摘要： Methods for deposition of elemental metal films on surfaces using metal coordination complexes comprising bisamineazaallylic ligands are provided. Also provided are bisamineazaallylic ligands useful in the methods of the invention and metal coordination complexes comprising these ligands.
摘要翻译：提供了使用包含双胺基间位配体的金属配位络合物在表面上沉积元素金属膜的方法。还提供了可用于本发明方法的双胺卡巴肼配体和包含这些配体的金属配位络合物。

62. 发明申请

US20130137772A1 HYDROXYPOLYAMINE SALTS 审中-公开
标题翻译：羟丙基淀粉盐
公开(公告)号：US20130137772A1
公开(公告)日：2013-05-30
申请号：US13306980
申请日：2011-11-29
申请人： Raymond J. Bergeron
发明人： Raymond J. Bergeron
IPC分类号： A61K31/132 , C07C309/04 , A61P1/18 , A61P35/00 , A61P13/12 , A61P1/16 , C07C211/13 , A61K31/205
CPC分类号： C07C215/18
摘要： A salt of a polyamine having the formula: with a pharmaceutically acceptable organic or inorganic acid, wherein at least one of the bridging groups ALK1, ALK2 and ALK3 contains at least one —CH(OH)-group which is not alpha- to any of the nitrogen atoms.
摘要翻译：具有下式的多胺的盐与药学上可接受的有机酸或无机酸形成，其中至少一个桥接基团ALK1，ALK2和ALK3含有至少一个-CH（OH） - 基团，其不是α- 氮原子。

63. 发明授权

US08361426B2 Absorption medium and method for removing sour gases from fluid streams, in particular from flue gases 有权
标题翻译：吸收介质和从流体流中特别是从烟道气中除去酸性气体的方法
公开(公告)号：US08361426B2
公开(公告)日：2013-01-29
申请号：US12999387
申请日：2009-06-09
申请人： Ute Lichtfers , Robin Thiele , Susanna Voges , Georg Sieder , Oliver Spuhl , Hugo Rafael Garcia Andarcia
发明人： Ute Lichtfers , Robin Thiele , Susanna Voges , Georg Sieder , Oliver Spuhl , Hugo Rafael Garcia Andarcia
IPC分类号： B01D53/40 , B01D53/14 , B01D53/78 , B01D53/96 , C07D241/04 , C07C211/13 , C07C211/14
CPC分类号： C10L3/10 , B01D53/1475 , B01D53/1493 , B01D2251/80 , B01D2253/102 , B01D2257/504 , C10L3/102 , Y02C10/06
摘要： Absorption medium for acid gases comprising an oligoamine (A) of the general formula (I) and a piperazine derivative (B) of the general formula (II) in which the weight ratio of oligoamine (A) to the piperazine derivative (B) is 0.2 to 25, and also process for removing acid gases from a gas stream by contacting the gas stream at a pressure of 0.05 to 10 MPa abs with an aqueous solution of said absorption medium which is brought to and maintained at a temperature of 20 to 80° C.
摘要翻译：含有通式（I）的低聚胺（A）和通式（II）的哌嗪衍生物（B）的酸性气体的吸收介质中，其中寡胺（A）与哌嗪衍生物（B）的重量比为 0.2至25，并且还通过使压力为0.05至10MPa abs的气流与所述吸收介质的水溶液接触并将其保持在20至80℃的温度下，从气流中除去酸性气体的方法 C。

64. 发明申请

US20120107502A1 Bisamineazaallylic Ligands And Their Use In Atomic Layer Deposition Methods 失效
标题翻译：双胺化合物配体及其在原子层沉积方法中的应用
公开(公告)号：US20120107502A1
公开(公告)日：2012-05-03
申请号：US13189644
申请日：2011-07-25
申请人： David Thompson , Jeffrey W. Anthis
发明人： David Thompson , Jeffrey W. Anthis
IPC分类号： C23C16/18 , C07F11/00 , C07F9/00 , H01L21/31 , C07F1/10 , C07F13/00 , C07C211/13 , C07D401/12 , C07F7/28 , C07F15/00
CPC分类号： C07F15/00 , C07C211/13 , C07F1/10 , C07F1/12 , C07F7/28 , C07F9/00 , C07F11/00 , C07F11/005 , C07F13/00 , C07F13/005 , C07F15/004 , C07F15/0053 , C07F15/0066 , C07F15/008 , C07F15/0093 , C23C16/18 , C23C16/45553
摘要： Methods for deposition of elemental metal films on surfaces using metal coordination complexes comprising bisamineazaallylic ligands are provided. Also provided are bisamineazaallylic ligands useful in the methods of the invention and metal coordination complexes comprising these ligands.
摘要翻译：提供了使用包含双胺基间位配位体的金属配位络合物在表面上沉积元素金属膜的方法。还提供了可用于本发明方法的双胺卡巴肼配体和包含这些配体的金属配位络合物。

65. 发明授权

US07608142B2 Process for the manufacture of a bitumen-aggregate mix suitable for road paving and a polyamine compound and its use 有权
标题翻译：用于制造适用于道路铺路的沥青骨料混合物和多胺化合物及其用途的方法
公开(公告)号：US07608142B2
公开(公告)日：2009-10-27
申请号：US11795002
申请日：2005-01-19
申请人： Bengt-Arne Thorstensson , Christos Edengrim
发明人： Bengt-Arne Thorstensson , Christos Edengrim
IPC分类号： C08L95/00 , C07C211/13 , C09D195/00 , B01F17/16
CPC分类号： C07C211/14 , C08K5/17 , C08L95/00 , Y10S516/914 , C08L95/005 , C08L2666/74 , C08L2666/72
摘要： According to the invention, a slow setting bitumen-aggregate mix for cold paving is manufactured by a) preparing a cationic oil-in-water emulsion of bitumen in the presence of an emulsifier containing i) a tertiary polyamine selected from the group consisting of a di(C2-C3 alkylene)triamine, a tri(C2-C3 alkylene)tetraamine, a tetra(C2-C3 alkylene)pentaamine, a penta(C2-C3 alkylene)hexaamine, a hexa(C2 C3 alkylene)heptaamine or a mixture thereof, which amine compounds have only tertiary amine groups and contain one or two aliphatic groups with 8-22 carbon atoms, bound to a nitrogen atom, while the remaining nitrogen substituents are methyl groups and ii) an acid present in such an amount that the aqueous emulsion obtains a pH value from 1-6, preferably 1.5-5, and b) mixing the aqueous emulsion obtained with a solid aggregate. The present invention also comprises a tertiary polyamine selected from said group of tertiary polyamines or a salt thereof with an acid, a process for the production of said tertiary amine, as well as the use of the tertiary polyamine salt as an emulsifying or cohesion increasing agent.
摘要翻译：根据本发明，用于冷铺路的缓慢设定的沥青骨料混合物通过以下步骤制造：a）在乳化剂存在下制备阳离子水包油乳液，所述乳化剂包含：i）选自以下的第三种多胺：二（C 2 -C 3亚烷基）三胺，三（C 2 -C 3亚烷基）四胺，四（C 2 -C 3亚烷基）五胺，五（C 2 -C 3亚烷基）六胺，六（C 2 -C 3亚烷基）其中胺化合物仅具有叔胺基团并且含有一个或两个与氮原子结合的碳原子数为8-22个的脂族基团，而其余的氮取代基是甲基，和ii）以如下方式存在的酸：水乳液获得1-6的pH值，优选为1.5-5，和b）将获得的水性乳液与固体聚集体混合。本发明还包括选自所述叔胺多元胺或其盐与酸的叔胺，用于生产所述叔胺的方法，以及使用叔多胺盐作为乳化剂或内聚力增加剂。

66. 发明申请

US20070161059A1 N1,n12-diacetylspermine as tumor marker 审中-公开
标题翻译： N1，n12-二乙酰精胺作为肿瘤标志物
公开(公告)号：US20070161059A1
公开(公告)日：2007-07-12
申请号：US10548658
申请日：2004-03-11
申请人： Masao Kawakita , Kyoko Hiramatsu , Keiichi Takahashi , Naotaka Hamasaki , Koji Yamaguchi , Tsunehisa Kaku , Koichiro Muta , Munechika Enjoji , Seiji Naito , Jun Hayashi , Shoshu Mitsuyama , Hiroyuki Yamashita , Toru Inoue , Masato Kato
发明人： Masao Kawakita , Kyoko Hiramatsu , Keiichi Takahashi , Naotaka Hamasaki , Koji Yamaguchi , Tsunehisa Kaku , Koichiro Muta , Munechika Enjoji , Seiji Naito , Jun Hayashi , Shoshu Mitsuyama , Hiroyuki Yamashita , Toru Inoue , Masato Kato
IPC分类号： G01N33/574 , C07C211/13
CPC分类号： G01N33/574 , C07K16/30
摘要： A tumor marker comprising diacetylspermine, and a method of evaluating the state of a tumor, comprising reacting an antibody to diacetylspermine with a biological sample to thereby detect diacetylspermine and evaluating the state of the tumor using the obtained detection results as an indicator.
摘要翻译：包含二乙酰精胺的肿瘤标记物和评估肿瘤状态的方法，包括使抗体与二乙酰精胺与生物样品反应，从而检测二乙酰精胺，并使用获得的检测结果作为指标来评价肿瘤的状态。

67. 发明授权

US06949679B1 Polyamine transport inhibitors 失效
标题翻译：多胺转运抑制剂
公开(公告)号：US06949679B1
公开(公告)日：2005-09-27
申请号：US09529319
申请日：1998-04-21
申请人： Richard Poulin , Marie Audette , Rene Charest-Gaudrealt
发明人： Richard Poulin , Marie Audette , Rene Charest-Gaudrealt
IPC分类号： C07C211/13 , C07C211/22 , C07C211/23
CPC分类号： C07C211/22 , C07C211/23
摘要： The present invention describes the design, synthesis and therapeutic use of a variety of novel inhibitors of polyamine transport. The main feature of this class of transport inhibitors is to incorporate a linker or side chain that prevents the uptake of polyamines and helps to conjugate polyamine analogs to form dimers with high inhibitory potency against polyamine uptake. These new compounds incorporate features that are designed to maximize their chemical and metabolic stability and their ability to bind to the polyamine transporter, and to minimize their toxicity by preventing their absorption by the cells. The purpose of such inhibitors is to prevent the uptake or salvaging of circulating polyamines by rapidly proliferating cells such as tumor cells, in order to potentiate the effect of therapeutic inhibitors of polyamine biosynthesis such as alpha-difluoromethylornithene.
摘要翻译：本发明描述了多胺转运的各种新型抑制剂的设计，合成和治疗用途。这类运输抑制剂的主要特征是引入一个阻止多胺摄取的接头或侧链，并有助于多胺类似物的结合形成具有高多胺吸收抑制效能的二聚体。这些新化合物包含被设计为使其化学和代谢稳定性最大化的能力，以及它们与多胺转运蛋白结合的能力，并通过防止细胞吸收来最小化其毒性。这种抑制剂的目的是通过快速增殖细胞如肿瘤细胞来防止循环多胺的摄取或回收，以增强多胺生物合成的治疗抑制剂如α-二氟甲基甲锗烷酮的作用。

68. 发明申请

US20020061287A1 Process of making a compound by forming a polymer from a template drug 有权
标题翻译：通过从模板药物形成聚合物制备化合物的方法
公开(公告)号：US20020061287A1
公开(公告)日：2002-05-23
申请号：US10004763
申请日：2001-12-05
发明人： Jon A. Wolff , James E. Hagstrom , Vladimir G. Budker , Vladimir S. Trubetskoy , Paul M. Slattum , Lisa J. Hanson
IPC分类号： A61K048/00 , C07C211/13
CPC分类号： C12N15/87 , A61K47/59 , A61K47/60 , A61K47/645 , A61K48/00 , A61K48/0008 , A61K48/0025 , A61K48/0041
摘要： A method of forming polymers in the presence of nucleic acid using template polymerization. Also, a method of having the polymerization occur in heterophase systems. These methods can be used for the delivery of nucleic acids, for condensing the nucleic acid, for forming nucleic acid binding polymers, for forming supramolecular complexes containing nucleic acid and polymer, and for forming an interpolyelectrolyte complex.
摘要翻译：使用模板聚合在核酸存在下形成聚合物的方法。此外，在异相体系中发生聚合的方法。这些方法可用于递送核酸，用于冷凝核酸，用于形成核酸结合聚合物，用于形成含有核酸和聚合物的超分子复合物，并用于形成内聚电解质络合物。

69. 发明授权

US6046359A Catalysts for the amination of alkylene oxides, alcohols, aldehydes and ketones 有权
标题翻译：用于胺化环氧烷，醇，醛和酮的催化剂
公开(公告)号：US6046359A
公开(公告)日：2000-04-04
申请号：US262262
申请日：1999-03-04
申请人： Joachim Wulff-Doring , Johann-Peter Melder , Gerhard Schulz , Guido Voit , Gutshoven Frank , Wolfgang Harder
发明人： Joachim Wulff-Doring , Johann-Peter Melder , Gerhard Schulz , Guido Voit , Gutshoven Frank , Wolfgang Harder
IPC分类号： B01J23/89 , C07B61/00 , C07C209/02 , C07C209/14 , C07C209/16 , C07C209/26 , C07C211/10 , C07C211/13 , C07C213/02 , C07C215/14 , C07C209/00
CPC分类号： C07C209/16 , B01J23/8926 , B01J23/8933
摘要： A catalyst comprises, based on the total weight of the catalyst,0.1-6% by weight of cobalt, nickel or a mixture thereof,0.001-25% by weight of ruthenium,0-10% by weight of copper and0-5% by weight of promoterson a porous metal oxide carrier.It preferably comprises 0.1-3% by weight of cobalt and 0.1-3% by weight of nickel. It can be used in hydrogenation reactions, dehydrogenation reactions or hydrogenation/dehydrogenation reactions, in particular in the amination of alkylene oxides, alcohols, aldehydes or ketones with ammonia or primary or secondary amines.
摘要翻译：催化剂基于催化剂的总重量包含0.1-6重量％的钴，镍或其混合物，0.001-25重量％的钌，0-10重量％的铜和0-5重量％的多孔金属氧化物载体上的助催化剂。其优选包含0.1-3重量％的钴和0.1-3重量％的镍。它可用于氢化反应，脱氢反应或氢化/脱氢反应，特别是在用氨或伯或仲胺使环氧烷，醇，醛或酮胺化时。

70. 发明授权

US5834439A Highly packed polycationic ammonium, sulfonium and phosphonium lipids 失效
公开(公告)号：US5834439A
公开(公告)日：1998-11-10
申请号：US782783
申请日：1997-01-13
申请人： Alberto Haces , Valentina C. Ciccarone
发明人： Alberto Haces , Valentina C. Ciccarone
IPC分类号： C12N15/09 , A61K9/127 , C07C211/63 , C07C217/40 , C07C233/36 , C07C381/12 , C07F9/54 , C12N5/10 , C12N15/87 , A61K31/13 , C07C211/13
CPC分类号： C12N15/87 , A61K9/1272 , C07C211/63 , C07C217/40 , C07C233/36 , C07C381/12 , C07F9/5449 , C07F9/5463 , Y10S435/829
摘要： The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transformation of cells. Methods for their preparation and use as intracellular delivery agents are also disclosed.

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