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61. 发明授权

US07288617B2 Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof 有权
标题翻译：含有螺二芴单元和芴单元的共轭聚合物及其用途
公开(公告)号：US07288617B2
公开(公告)日：2007-10-30
申请号：US10472736
申请日：2002-03-22
申请人： Kevin Treacher , Heinrich Becker , Philipp Stossel , Hubert Spreitzer , Aurelie Falcou , Amir Parham , Arne Busing
发明人： Kevin Treacher , Heinrich Becker , Philipp Stossel , Hubert Spreitzer , Aurelie Falcou , Amir Parham , Arne Busing
IPC分类号： C08G61/02 , C08G61/12
CPC分类号： H01L51/0039 , C07C17/2632 , C07C25/22 , C07C43/225 , C07C2603/18 , C07C2603/94 , C08G61/02 , C08G61/12 , H01L51/0036 , H01L51/0043 , H01L51/0059 , H01L51/0508 , H01L51/5012 , Y02E10/549 , Y10S428/917
摘要： The present invention relates to novel polymers which comprise spirobifluorene and fluorine units of the formulae (I) and (II) and may further comprise additional structural elements which may have charge transport properties, hole transport properties and/or electron transport properties.Such materials display a significantly improved property profile in electronic components, particularly when used in a PLED, in particular as electroluminescence material, in organic integrated circuits (O-ICs), organic field effect transistors (OFETs), organic thin film transistors (OTFTs), organic solar cells (O-SCs) or organic laser diodes (O lasers).
摘要翻译：本发明涉及包含式（I）和（II）的螺二芴和氟单元的新型聚合物，并且还可以包含可具有电荷传输性质，空穴传输性质和/或电子传输性质的其它结构元件。特别是当在有机集成电路（O-IC），有机场效应晶体管（OFET），有机薄膜晶体管（OTFT））中用作PLED，特别是作为电致发光材料时，这些材料显示出显着改善的电子元件特性。有机太阳能电池（O-SC）或有机激光二极管（O激光器）。

62. 发明授权

US06979566B2 Method of treatment of viral infection including HIV using water soluble fullerenes—III 失效
标题翻译：使用水溶性富勒烯治疗病毒感染包括HIV的方法III
公开(公告)号：US06979566B2
公开(公告)日：2005-12-27
申请号：US10355365
申请日：2003-02-01
申请人： Simon H. Friedman , Raymond F. Schinazi , Fred Wudl , Craig L. Hill , Diane L. DeCamp , Rintje P. Sijbesma , George L. Kenyon
发明人： Simon H. Friedman , Raymond F. Schinazi , Fred Wudl , Craig L. Hill , Diane L. DeCamp , Rintje P. Sijbesma , George L. Kenyon
IPC分类号： C07C13/64 , C07C49/255 , C07C55/00 , C07C57/50 , C07C211/27 , C07C211/42 , C07C211/50 , C07C233/36 , C07D231/56 , C07D233/54 , C07D239/26 , C07D261/08 , C07D471/10 , C07D487/10 , C07C229/37
CPC分类号： C07C57/50 , C07C13/64 , C07C49/255 , C07C55/00 , C07C211/27 , C07C211/42 , C07C211/50 , C07C233/36 , C07C2601/00 , C07C2601/14 , C07C2603/18 , C07C2603/94 , C07D231/56 , C07D233/64 , C07D239/26 , C07D261/08 , C07D471/10 , C07D487/10 , Y10S977/904
摘要： A water soluble derivative of buckministerfullerene (C50) having antiviral and virucidal properties is used to inhibit human retroviral replication and infections. The derivatized fullerene is symmetrically substituted with polar organic moieties containing 1 to 20 carbon atoms and optionally further containing oxygen or nitrogen.
摘要翻译：使用具有抗病毒和杀病毒性质的buckministerfullerene（C 50 S）的水溶性衍生物来抑制人类逆转录病毒复制和感染。衍生的富勒烯被含有1至20个碳原子的极性有机部分对称地取代，并且任选地还含有氧或氮。

63. 发明申请

US20050233165A1 Anthracene derivatives and organic electroluminescent devices made by using the same 审中-公开
标题翻译：蒽衍生物和使用它们的有机电致发光器件
公开(公告)号：US20050233165A1
公开(公告)日：2005-10-20
申请号：US10519934
申请日：2003-07-29
申请人： Motohisa Ido , Masakazu Funahashi , Hiroshi Tokairin
发明人： Motohisa Ido , Masakazu Funahashi , Hiroshi Tokairin
IPC分类号： H01L51/50 , C07C13/567 , C07C13/573 , C07C13/60 , C07C13/66 , C07C13/72 , C07C15/28 , C07C17/12 , C07C46/00 , C07C49/665 , C07F7/08 , C09K11/06 , H01L51/00 , H01L51/30 , H05B33/14 , H05B33/12
CPC分类号： C07C13/72 , C07C13/567 , C07C13/60 , C07C13/66 , C07C15/28 , C07C17/12 , C07C46/00 , C07C49/665 , C07C2602/10 , C07C2603/18 , C07C2603/24 , C07C2603/26 , C07C2603/50 , C07C2603/94 , C07C2603/97 , C07F7/0807 , C09K11/06 , C09K2211/1011 , H01L51/0052 , H01L51/0058 , H01L51/0059 , H01L51/006 , H01L51/0081 , H01L51/5012 , H01L2251/308 , H05B33/14 , C07C25/22 , C07C50/16
摘要： An anthracene derivative represented by the following general formula (1) which enables an organic electroluminescence device to exhibit a great efficiency of light emission and uniform light emission even at high temperatures since crystallization is suppressed and no thermal decomposition takes place during vapor deposition and an organic electroluminescence device utilizing the derivative, are provided. [Ar represents a group represented by the following general formula (2): (L1 and L2 each represent a substituted or unsubstituted methylene group, ethylene group or the like, and at least one of them is present), Ar′ represents a substituted or unsubstituted aryl group having 6 to 50 nuclear carbon atoms, X represent an alkyl group or the like, a and b each represent an integer of 0 to 4, and n represents an integer of 1 to 3.]
摘要翻译：由下述通式（1）表示的蒽衍生物，即使在高温下也能使有机电致发光元件显示出高的发光效率和均匀的发光，因为抑制结晶，并且在气相沉积期间不发生热分解，并且有机提供了使用该衍生物的电致发光器件。 [Ar表示由以下通式（2）表示的基团：（L 1和L 2）各自表示取代或未取代的亚甲基，亚乙基等，并且其中至少有一个存在），Ar'表示具有6至50个核碳原子的取代或未取代的芳基，X表示烷基等，a和b各自表示0〜4的整数，n 表示1〜3的整数。]

64. 发明申请

US20050067955A1 Compound derived from cyclopentadienone, preparation method thereof and EL element using the same 审中-公开
标题翻译：衍生自环戊二烯酮的化合物，其制备方法和使用其的EL元件
公开(公告)号：US20050067955A1
公开(公告)日：2005-03-31
申请号：US10937906
申请日：2004-09-10
申请人： Hyun-Nam Cho , Sung Jung , Seok-Jin Park , Seung-Eun Lee
发明人： Hyun-Nam Cho , Sung Jung , Seok-Jin Park , Seung-Eun Lee
IPC分类号： H01L51/50 , C07C2/00 , C07C13/32 , C07C13/547 , C07C13/567 , C07C13/72 , C07C41/30 , C07C43/205 , C07C43/21 , C07C209/68 , C07C211/54 , C07C249/16 , C07C251/84 , C07D209/86 , C07D333/10 , C07D333/16 , C07D413/14 , C09K11/06 , H05B33/14 , C07D49/14
CPC分类号： C07D209/86 , C07C13/567 , C07C13/72 , C07C43/2055 , C07C49/683 , C07C49/753 , C07C49/792 , C07C211/54 , C07C251/84 , C07C2601/10 , C07C2603/18 , C07C2603/40 , C07C2603/42 , C07C2603/94 , C07D333/08 , C09K11/06 , C09K2211/1007 , C09K2211/1011 , C09K2211/1014 , C09K2211/1029 , C09K2211/1048 , C09K2211/1088 , C09K2211/1092 , H01L51/005 , H01L51/0052 , H01L51/0058 , H01L51/0059 , H01L51/0068 , H01L51/0071 , H01L51/0072
摘要： Disclosed are a compound represented by the following formula (1), which is derived from cyclopentadienone and can be used as a core material for an organic electroluminescence element or other optical devices, and preparation method thereof, and an EL element using the same.
摘要翻译：公开了由下式（1）表示的化合物，其衍生自环戊二烯酮，可用作有机电致发光元件或其它光学器件的芯材及其制备方法，以及使用该化合物的EL元件。

65. 发明授权

US06844368B1 Compounds useful in pain management 失效
标题翻译：化合物可用于疼痛管理
公开(公告)号：US06844368B1
公开(公告)日：2005-01-18
申请号：US09460723
申请日：1999-12-14
申请人： Edward Roberts , Tiechao Li , Dilip Dixit , Krzysztof Bednarski , Jean-Francois Lavallée , Dick Storer , Wuyi Wang
发明人： Edward Roberts , Tiechao Li , Dilip Dixit , Krzysztof Bednarski , Jean-Francois Lavallée , Dick Storer , Wuyi Wang
IPC分类号： A61K31/135
CPC分类号： C07C217/52 , C07C2602/10 , C07C2603/94
摘要： The present invention relates to novel oxo-aminotetralin compounds of the formula (I) wherein X, R1, R2, R3, R4, R5, and R6 are defined herein. The compounds of formula (I) are useful in pain management.
摘要翻译：本发明涉及式（I）的新型氧代 - 氨基四氢化萘化合物，其中X，R 1，R 2，R 3，R 4，R 5和R 6在本文中定义。式（I）化合物可用于疼痛管理。

66. 发明授权

US06717017B2 Total synthesis of antitumor acylfulvenes 失效
标题翻译：全合成抗肿瘤酰胆碱
公开(公告)号：US06717017B2
公开(公告)日：2004-04-06
申请号：US10231575
申请日：2002-08-30
申请人： Trevor C. McMorris
发明人： Trevor C. McMorris
IPC分类号： C07C3537
CPC分类号： C07D493/08 , C07C35/37 , C07C49/737 , C07C2603/94 , Y02P20/55 , Y02P20/582
摘要： The present invention provides a method of synthesizing compounds of formula (I) or (II): wherein R1 is hydrogen, R′ is (C1-C4)alkyl and X is a hydroxyl protecting group.
摘要翻译：本发明提供合成式（I）或（II）化合物的方法：其中R 1是氢，R'是（C 1 -C 4）烷基，X是羟基保护基。

67. 发明申请

US20020169336A1 Phenylalanine enamide derivatives 失效
标题翻译：苯丙氨酸烯酰胺衍生物
公开(公告)号：US20020169336A1
公开(公告)日：2002-11-14
申请号：US10081072
申请日：2002-02-22
发明人： Stephen Brand , Stuart Bailey , Julien A. Brown , James A. Johnson , John R. Porter , John C. Head
IPC分类号： C07C255/45 , C07C229/46 , C07C061/16
CPC分类号： C07D213/81 , C04B35/632 , C07C229/10 , C07C229/46 , C07C233/81 , C07C233/82 , C07C323/30 , C07C2601/04 , C07C2603/94 , C07C2603/96 , C07D213/79 , C07D213/89 , C07D311/96 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D471/04
摘要： Phenylalanine enamide derivatives of formula (1) are described: 1 wherein R1 is a group Ar1L2Ar2Alk- in which: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a covalent bond or a linker atom or group; Ar2 is an optionally substituted arylene or heteroarylene group; and Alk is a chain nullCH2nullCH(R)13 , nullCHnullC(R)null or 2 nullin which R is a carboxylic acid (nullCO2H) or a derivative or biostere thereof; X is an nullOnull or nullSnull atom or nullN(R2)null group in which: Rx, Ry and Rz which may be the same or different is each a hydrogen atom or an optional substituent; or Rz is an atom or group as previously defined and Rx and Ry are joined together to form an optionally substituted spiro linked cycloaliphatic or heterocycloaliphatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells.
摘要翻译：描述式（1）的苯丙氨酸烯酰胺衍生物：其中R1是Ar1L2Ar2Alk-基团，其中：Ar1是任选取代的芳族或杂芳族基团; L2是共价键或连接原子或基团; Ar 2是任选取代的亚芳基或亚杂芳基; 并且Alk是链-CH 2 -CH（R）13，-CH = C（R） - 或其中R是羧酸（-CO 2 H）或其衍生物或生物试剂; X是-O-或-S-原子或-N（R 2） - 基团，其中：可以相同或不同的R x，R y和R z各自为氢原子或任选的取代基; 或R z是如先前定义的原子或基团，并且R x和R y连接在一起以形成任选取代的螺环连接的脂环族或杂环脂族基团; 及其盐，溶剂合物，水合物和N-氧化物。这些化合物能够抑制整联蛋白与其配体的结合，并且可用于预防和治疗涉及细胞不适当生长或迁移的免疫或炎性疾病或病症

68. 发明授权

US06252093B1 Total synthesis of antitumor acylfulvenes 失效
标题翻译：全合成抗肿瘤酰胆碱
公开(公告)号：US06252093B1
公开(公告)日：2001-06-26
申请号：US09679831
申请日：2000-10-05
申请人： Trevor C. McMorris
发明人： Trevor C. McMorris
IPC分类号： C07D30793
CPC分类号： C07D493/08 , C07C35/37 , C07C49/737 , C07C2603/94 , Y02P20/55 , Y02P20/582
摘要： A compound of formula (IV): wherein R′ and R9 are each independently (C1-C4)alkyl.
摘要翻译：式（IV）的化合物：其中R'和R 9各自独立地为（C 1 -C 4）烷基

69. 发明授权

US06242413B1 Bicyclic aldehyde and ketone odorants 失效
标题翻译：双环醛和酮气味剂
公开(公告)号：US06242413B1
公开(公告)日：2001-06-05
申请号：US09324335
申请日：1999-06-02
申请人： Georg Frater , Philip Kraft
发明人： Georg Frater , Philip Kraft
IPC分类号： A61K746
CPC分类号： C11B9/0049 , C07C13/72 , C07C45/69 , C07C47/445 , C07C49/553 , C07C2602/14 , C07C2602/26 , C07C2603/94
摘要： The invention relates to bicyclic aldehydes and ketones of formula (I): wherein n is 1 or 2; R1 and R4 are independently H or CH3; and R2 and R3 are independently H, CH3 or CH2CH3 The invention also provides odorant compositions containing at least one compound of formula (I). A process for the manufacture of R1-methyl substituted compounds of formula (I) having a bridgehead-positioned double bond, as well as intermediates thereof is also provided.
摘要翻译：本发明涉及式（I）的双环醛和酮：其中n为1或2; R 1和R 4独立地为H或CH 3; 并且R 2和R 3独立地为H，CH 3或CH 2 CH 3。本发明还提供含有至少一种式（I）化合物的气味组合物。还提供了制备具有桥头定位双键的式（I）的R1-甲基取代的化合物及其中间体的方法。

70. 发明授权

US3706756A Aminoalkyl-spirocycloalkanes 失效
标题翻译：氨基酸 - 螺旋藻
公开(公告)号：US3706756A
公开(公告)日：1972-12-19
申请号：US3706756D
申请日：1969-02-03
申请人： CIBA GEIGY CORP
发明人： WERNER LINCOLN HARVEY
IPC分类号： C07C47/453 , C07C49/675 , C07C49/755 , C07C205/04 , C07D211/22 , C07C87/28 , C07D27/56 , C07D31/44
CPC分类号： C07D211/22 , C07C47/453 , C07C49/675 , C07C49/755 , C07C213/02 , C07C2603/94 , C07C217/60 , C07C215/52 , C07C217/62
摘要： 1-AMINOALKYL-BENZCYCLOALKANE-2-SPIROCYCLOALIPHATIC COMPOUNDS, E.G. THOSE OF THE FORMULA

(-B-)>C
ALK=LOWER ALKYLENE AM=AN AMINO GROUP R=H OR OH; M=1-3 B=LOWER ALKYLENE OR ALKENYLENE ACYL AND 1-DEHYDRO DERIVATIVES, N-OXIDES, QUARTERMARIES AND SALT THEREOF EXHIBIT ANALGETIC EFFECTS.

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