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    • 65. 发明授权
    • Process for the preparation of aliphatic tertiary amides
    • 制备脂肪酸乳液的方法
    • US3674851A
    • 1972-07-04
    • US3674851D
    • 1970-03-31
    • ASAHI CHEMICAL IND
    • SENOO SABUROFUKUOKA YOHEISASAKI KATUYOSHI
    • B01D11/04C07C231/00C07C233/00C07C103/00
    • C07C231/00B01D11/04C07C233/00Y02P20/582
    • This invention discloses a process for the preparation of aliphatic tertiary amides which comprises reacting a fatty acid represented by the general formula R1COOH wherein R1 is a hydrogen atom or an alkyl group having one to six carbon atoms and ammonia directly with an alcohol represented by the general formula R2OH wherein R2 is an alkyl group having one to four carbon atoms at a temperature of 100* C. to 800* C. under pressure, said ammonia and alcohol being employed in amounts of 0.8 to five moles and 1.5 to ten moles per mole of fatty acid, respectively. In this process, there may be additionally employed a catalyst to accelerate the rate of reaction. Also, in this invention all or part of starting materials remaining unreacted and/or by-products may be recycled to the starting reaction mixture, thereby enabling the yield of the desired aliphatic tertiary amides to be remarkably improved. In addition, the removal of the water which is produced during the course of reaction assists the present process to be further improved. Thus, according to the present invention, aliphatic tertiary amides can be simply produced with excellent yields from the raw materials which are readily available at low cost, as opposed to the conventional process employing as a starting material dialkylamines which are difficult to obtain in the purified form.
    • 本发明公开了一种制备脂肪族叔酰胺的方法,该方法包括使通式为R 1 COOH(其中R 1为氢原子或具有1至6个碳原子的烷基)和氨直接与通式 式R2OH其中R2是在100℃至800℃的温度下在压力下具有1-4个碳原子的烷基,所述氨和醇的用量为每摩尔0.8至5摩尔和1.5至10摩尔 的脂肪酸。 在该方法中,可以另外使用催化剂来加速反应速率。 此外,在本发明中,保留未反应和/或副产物的原料的全部或部分可以再循环到起始反应混合物中,从而使所需脂族叔酰胺的产率显着提高。 此外,在反应过程中产生的水的去除有助于进一步改进本方法。 因此,根据本发明,与原料中使用难以获得的二烷基胺的常规方法相反,根据本发明,脂肪族叔酰胺可以简单地以低成本容易获得的原料的良好收率生产, 形成。