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61. 发明授权

US4963128A Chest tube and catheter grid for intrathoracic afterload radiotherapy 失效
标题翻译：胸管和导管网格用于胸腔后负荷放疗
公开(公告)号：US4963128A
公开(公告)日：1990-10-16
申请号：US326733
申请日：1989-03-21
申请人： Thomas M. Daniel , Seung S. Hahn
发明人： Thomas M. Daniel , Seung S. Hahn
IPC分类号： A61M1/00 , A61M27/00 , A61M36/12 , A61N5/10
CPC分类号： A61N5/1007 , A61M1/008 , A61M27/00 , A61N2005/1012
摘要： An apparatus and method for intraoperative internal placement of an afterloading catheter tube grid for post-operative radiotherapy using a semi-rigid tube having inserted within a plurality of catheters which extends outwardly from the distal end of the semi-rigid tube for a predetermined distance and attaching these distally outward extending catheter tubes to a soft sheet so that the catheter tube maintain a parallel position to one another over the predetermined distance. The proximal ends of these catheter tubes extend outwardly from the proximal end of the semi-rigid tube and are located on the outside of the body. These proximal ends of the catheters are left open for loading of the radioactive material into these catheter tubes, while the distal ends are closed to prevent airleak and to stop the radioactive material. The soft sheet is provided with eyelets at each of the four corners, and these eyelets are used to secure the soft sheet with sutures to the inside of the cavity wall over the area intended for radiation therapy. A stiff cover cap is provided so as to cover the furled soft sheet, and this cover cap attaches to the distal end of the semi-rigid tube. This cover cap is removed when the present invention is inserted into the body cavity.
摘要翻译：一种用于术中内置放置用于术后放射治疗的后置导管管网格的装置和方法，其使用插入在从半刚性管的远端向外延伸预定距离的多个导管内的半刚性管，以及将这些远端向外延伸的导管连接到软片上，使得导管管在预定距离上保持彼此平行的位置。这些导管的近端从半刚性管的近端向外延伸并且位于身体的外侧。导管的这些近端保持开放，用于将放射性物质装载到这些导管中，而远端封闭以防止空气泄漏并停止放射性物质。软片在四个角中的每一个处设置有孔眼，并且这些孔眼用于将缝合的软片固定在用于放射治疗的区域上的腔壁内部。提供一个刚性的盖帽，以便覆盖卷发的软片，并且该盖帽附接到半刚性管的远端。当将本发明插入体腔时，该盖帽被去除。

62. 发明授权

US4815449A Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member 失效
标题翻译：用于间质放射治疗的递送系统，包括基本上非偏转的细长构件
公开(公告)号：US4815449A
公开(公告)日：1989-03-28
申请号：US031885
申请日：1987-03-30
申请人： Bruce S. Horowitz
发明人： Bruce S. Horowitz
IPC分类号： A61M36/04 , A61M36/12 , A61N5/10 , A61N5/01
CPC分类号： A61N5/1001 , A61M37/0069 , A61N2005/1012 , A61N2005/1023 , A61N2005/1024 , A61N5/1014 , A61N5/1027
摘要： A delivery system for interstitial radiation therapy comprising a substantially non-deflecting elongated member of material which is absorbable in living tissue and a plurality of radioactive seeds dispersed in a predetermined array within the member. In one form, the member comprises an elongated member having the seeds longitudinally spaced therein and forming a needle that can be inserted in the tumor to be treated.
摘要翻译：一种用于间质放射治疗的递送系统，包括可在生物体组织中吸收的基本上非偏转的细长材料元件和以该组件内预定阵列分散的多个放射性种子。在一种形式中，构件包括具有在其中纵向间隔开的种子的细长构件，并形成可插入待治疗的肿瘤中的针。

63. 发明授权

US2959166A Apparatus for applying radioactive therapy in the pelvic cavity of the body 失效
标题翻译：用于在体内盆腔施用放射治疗的装置
公开(公告)号：US2959166A
公开(公告)日：1960-11-08
申请号：US46913654
申请日：1954-11-16
申请人： CLAYTON RALPH S
发明人： CLAYTON RALPH S
IPC分类号： A61M31/00 , A61N5/10
CPC分类号： A61M31/00 , A61N5/1007 , A61N5/1014 , A61N2005/1012

64. 发明授权

US11872409B2 Radiotherapy template assembly 有权
公开(公告)号：US11872409B2
公开(公告)日：2024-01-16
申请号：US17925838
申请日：2021-10-27
申请人： ALPHA TAU MEDICAL LTD.
发明人： Ofer Magen , Niv Dana , Sagy Tal , Amnon Gat , Robert Den
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61N5/1014 , A61N2005/1012 , A61N2005/1018
摘要： A template assembly including a first grid (22) for placement on a first side of a body organ, defining a plurality of apertures (329) adapted to receive elongate applicators (410), a second grid (24) for placement on a second side of a body organ, defining a plurality of apertures (34), adapted to receive applicators passing through apertures of the first grid and the body organ and at least one frame (26) defining a large hole (72), positioned between the first and second grids and configured to grasp the body organ.

65. 发明授权

US09808649B2 Immobilization system to support an in vivo medical device 有权
公开(公告)号：US09808649B2
公开(公告)日：2017-11-07
申请号：US15399805
申请日：2017-01-06
申请人： Medical Tool & Technology, LLC
发明人： Richard David Helmig , John Scott Wheeler
IPC分类号： A61N5/10 , A61F5/37
CPC分类号： A61N5/10 , A61F5/3776 , A61N5/1016 , A61N2005/1012 , A61N2005/1097
摘要： The problem of securing the position of an internally placed medical device that extends out of the body during targeted high-dose-rate (HDR) brachytherapy is solved by a uniquely configured immobilization system that can be utilized to stabilize medical devices placed, for example, within the uterus or cervix. During the process of transporting a patient from the location where the HDR applicator is emplaced, for example, where the tandem and ring is placed within the cervix of a patient, to the location where the treatment is actually applied to the tissue, the medical device can move out of place and in so doing cause discomfort, pain, or an ineffective treatment for the patient. The embodiments of this immobilization system can include a strap apparatus, a straddling girdle, and bracket that can be attached to a patient. This immobilization system ensures the position of an internally placed medical device during targeted HDR brachytherapy.

66. 发明授权

US09320915B2 Brachytherapy tandem and ovoid implantation devices and methods 有权
标题翻译：近距离放射治疗串联和卵形植入装置及方法
公开(公告)号：US09320915B2
公开(公告)日：2016-04-26
申请号：US14613038
申请日：2015-02-03
申请人： Mark A. D'Andrea
发明人： Mark A. D'Andrea
IPC分类号： A61N5/10 , A61B18/04 , A61B18/00
CPC分类号： A61N5/1016 , A61B18/04 , A61B2017/22051 , A61B2017/22054 , A61B2017/22055 , A61B2017/22061 , A61B2017/22062 , A61B2017/22068 , A61B2017/22069 , A61B2018/00273 , A61B2018/00285 , A61B2018/00559 , A61B2018/046 , A61B2090/033 , A61B2090/0445 , A61B2090/0481 , A61N5/1067 , A61N5/1071 , A61N2005/1003 , A61N2005/1012 , A61N2005/1094
摘要： Intracavitary brachytherapy tandem and ovoid oncology treatment systems and methods are provided. One such system and method employs a multi-part tandem having a detachable distal section suitable for retaining within a body cavity such as the uterus, both during radiation treatment and during recovery time between radiation treatments. This distal portion can be intended for single-patient use and be disposed of after completion of a radiation treatment session having multiple radiation dose treatment times. One or both of real time in vivo detection and monitoring and hypertherapy features can be included. One or more of the system tandem or ovoid colpostats feature bendability to tailor the system to the specific body and patient being treated. The method includes having a tandem distal section inserted into a body cavity such as a uterus and remaining within the body cavity in between treatment times. Other systems and methods incorporate balloon devices that assist in spacing radiation doses away from body sites at which radiation treatment is not intended. Balloon devices also can be provided for adjusting and maintaining separation spacing between two ovoid colpostats while intracavitary.
摘要翻译：提供腔内近距离放射治疗系统和卵巢肿瘤治疗系统和方法。一种这样的系统和方法采用多部分串联，其具有适于在放射治疗期间和在放射治疗之间的恢复时间期间保持在诸如子宫的体腔内的可分离远端部分。该远端部分可以用于单次患者使用，并且在完成具有多个辐射剂量治疗时间的放射治疗会话之后进行处置。可以包括实时体内检测和监测和超治疗特征中的一个或两个。一个或多个系统串联或卵巢粘滞剂具有弯曲性，可以将系统定制到被治疗的特定身体和患者。该方法包括将串联远端部分插入到诸如子宫的体腔中并在治疗时间之间保留在体腔内。其他系统和方法包括气球装置，其有助于将辐射剂量与远离身体部位的辐射处理隔开。还可以提供气球装置用于在腔内调节和保持两个卵状粘液瓶之间的间隔。

67. 发明申请

US20150157878A1 BRACHYTHERAPY TANDEM AND OVOID IMPLANTATION DEVICES AND METHODS 审中-公开
公开(公告)号：US20150157878A1
公开(公告)日：2015-06-11
申请号：US14613038
申请日：2015-02-03
申请人： Mark A. D'Andrea
发明人： Mark A. D'Andrea
IPC分类号： A61N5/10
CPC分类号： A61N5/1016 , A61B18/04 , A61B2017/22051 , A61B2017/22054 , A61B2017/22055 , A61B2017/22061 , A61B2017/22062 , A61B2017/22068 , A61B2017/22069 , A61B2018/00273 , A61B2018/00285 , A61B2018/00559 , A61B2018/046 , A61B2090/033 , A61B2090/0445 , A61B2090/0481 , A61N5/1067 , A61N5/1071 , A61N2005/1003 , A61N2005/1012 , A61N2005/1094
摘要： Intracavitary brachytherapy tandem and ovoid oncology treatment systems and methods are provided. One such system and method employs a multi-part tandem having a detachable distal section suitable for retaining within a body cavity such as the uterus, both during radiation treatment and during recovery time between radiation treatments. This distal portion can be intended for single-patient use and be disposed of after completion of a radiation treatment session having multiple radiation dose treatment times. One or both of real time in vivo detection and monitoring and hypertherapy features can be included. One or more of the system tandem or ovoid colpostats feature bendability to tailor the system to the specific body and patient being treated. The method includes having a tandem distal section inserted into a body cavity such as a uterus and remaining within the body cavity in between treatment times. Other systems and methods incorporate balloon devices that assist in spacing radiation doses away from body sites at which radiation treatment is not intended. Balloon devices also can be provided for adjusting and maintaining separation spacing between two ovoid colpostats while intracavitary.
摘要翻译：提供腔内近距离放射治疗系统和卵巢肿瘤治疗系统和方法。一种这样的系统和方法采用多部分串联，其具有适于在放射治疗期间和在放射治疗之间的恢复时间期间保持在诸如子宫的体腔内的可分离远端部分。该远端部分可以用于单次患者使用，并且在完成具有多个辐射剂量治疗时间的放射治疗会话之后进行处置。可以包括实时体内检测和监测和超治疗特征中的一个或两个。一个或多个系统串联或卵巢粘滞剂具有弯曲性，可以将系统定制到被治疗的特定身体和患者。该方法包括将串联远端部分插入到诸如子宫的体腔中并在治疗时间之间保留在体腔内。其他系统和方法包括气球装置，其有助于将辐射剂量与远离身体部位的辐射处理隔开。还可以提供气球装置用于在腔内调节和保持两个卵状粘液瓶之间的间隔。

68. 发明授权

US08979725B2 Brachytherapy tandem and ovoid implantation devices and methods 有权
标题翻译：近距离放射治疗串联和卵形植入装置及方法
公开(公告)号：US08979725B2
公开(公告)日：2015-03-17
申请号：US13478794
申请日：2012-05-23
申请人： Mark A. D'Andrea
发明人： Mark A. D'Andrea
IPC分类号： A61N5/00 , A61M36/00 , A61M36/04 , A61M36/10 , A61M36/12 , A61N5/10
CPC分类号： A61N5/1016 , A61B18/04 , A61B2017/22051 , A61B2017/22054 , A61B2017/22055 , A61B2017/22061 , A61B2017/22062 , A61B2017/22068 , A61B2017/22069 , A61B2018/00273 , A61B2018/00285 , A61B2018/00559 , A61B2018/046 , A61B2090/033 , A61B2090/0445 , A61B2090/0481 , A61N5/1067 , A61N5/1071 , A61N2005/1003 , A61N2005/1012 , A61N2005/1094
摘要： Intracavitary brachytherapy tandem and ovoid oncology treatment systems and methods are provided. One such system and method employs a multi-part tandem having a detachable distal section retained within a body cavity during and between radiation treatments. This can be for single-patient use and disposed of after completion of a multiple-dose radiation treatment session. Real time in vivo detection and monitoring and hytpertherapy features can be included. Tandem or ovoid colpostats can feature bendability to tailor the system to the specific body and patient being treated. Other systems and methods incorporate balloon devices that assist in spacing radiation doses away from chosen body sites. Balloon devices also can be provided for adjusting and maintaining separation spacing between two ovoid colpostats.
摘要翻译：提供腔内近距离放射治疗系统和卵巢肿瘤治疗系统和方法。一种这样的系统和方法采用多部分串联，其中在放射治疗期间和之间具有保持在体腔内的可分离远端部分。这可以用于单次患者使用，并在多剂量放射治疗会话完成后进行处置。可以包括实时的体内检测和监测和疗法特征。串联或卵球蛋白凝块可以具有弯曲性，可以将系统定制到特定身体和被治疗的患者。其他系统和方法包括有助于将辐射剂量与所选择的身体部位隔开的球囊装置。还可以提供气球装置用于调节和保持两个卵巢凝块体之间的间隔。

69. 发明申请

US20150051861A1 QUALITY ASSURANCE SYSTEM AND METHOD FOR NAVIGATION-ASSISTED PROCEDURES 审中-公开
标题翻译：质量保证系统和导航辅助程序的方法
公开(公告)号：US20150051861A1
公开(公告)日：2015-02-19
申请号：US14388325
申请日：2013-03-26
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Jochen Kruecker , Shyam Bharat , Cynthia Ming-Fu Kung
IPC分类号： G01D18/00 , G01N29/04 , G01B7/00 , G01H17/00 , A61B5/06 , A61N5/10
CPC分类号： G01D18/00 , A61B5/061 , A61B17/3403 , A61B34/20 , A61B2017/00725 , A61B2017/3411 , A61N5/1007 , A61N2005/1012 , G01B7/003 , G01H17/00 , G01N29/04
摘要： A calibration system includes a channel block (102) having a plurality of channels (104) formed therein. The channels are configured to correspond to locations where treatment devices are inserted for treatment of a patient. The channels are dimensioned to restrict motion of the treatment devices. A tracking system (128) is configured to monitor a position of a treatment device (108) inserted in one or more of the channels. The tracking system is configured to generate tracking data for the at least one treatment device for comparison with an expected position for the treatment device.
摘要翻译：校准系统包括其中形成有多个通道（104）的通道块（102）。通道被配置为对应于处理装置被插入以治疗患者的位置。通道的尺寸被限制以限制治疗装置的运动。跟踪系统（128）被配置为监视插入在一个或多个通道中的治疗装置（108）的位置。跟踪系统被配置为产生用于至少一个治疗装置的跟踪数据，用于与治疗装置的预期位置进行比较。

70. 发明申请

US20140275971A1 Automatic Needle Insertion Location Identification 有权
标题翻译：自动针插入位置识别
公开(公告)号：US20140275971A1
公开(公告)日：2014-09-18
申请号：US13833593
申请日：2013-03-15
申请人： NEOCOIL, LLC
发明人： Brian Brown , Emad Abdelsalam , Paul Ropella , Steven Wolff
IPC分类号： A61B19/00 , G01R33/28
CPC分类号： A61B90/17 , A61B10/0275 , A61B17/3403 , A61B34/20 , A61B2017/00221 , A61B2017/3411 , A61B2090/0811 , A61M5/427 , A61N2005/1012 , G01R33/28 , G01R33/3692
摘要： A system for automatically identifying a needle insertion location from a medical diagnostic image, such as an MRI image, and providing a visual indication of the needle insertion location is disclosed. A grid plate is located proximate to an anatomical region and is preferably incorporated in an MRI support structure utilized to immobilize the anatomical region. An MRI scanner obtains an MRI image of the anatomical region, and an MRI technician places a marker on the MRI image, identifying the needle insertion location. The MRI image and the marker are transferred from the MRI scanner to another device, such as a tablet computer, which is configured to convert the MRI image and the marker to coordinates and an insertion depth. A visual indicator is located proximate to or integrated with the grid plate that provides the needle insertion coordinates and insertion depth to the MRI technician.
摘要翻译：公开了一种用于从医学诊断图像（例如MRI图像）自动识别针插入位置并提供针插入位置的视觉指示的系统。格栅板位于解剖区域附近，并且优选地并入用于固定解剖区域的MRI支撑结构中。 MRI扫描器获得解剖区域的MRI图像，并且MRI技术人员将标记放置在MRI图像上，识别针插入位置。 MRI图像和标记从MRI扫描器传送到另一个设备，例如平板计算机，其被配置为将MRI图像和标记转换为坐标和插入深度。视觉指示器位于栅格板附近或与栅板一体化，其向MRI技术人员提供针插入坐标和插入深度。

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