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61. 发明授权

US08301265B2 Selective depth electrode deployment for electrical stimulation 失效
标题翻译：用于电刺激的选择性深度电极部署
公开(公告)号：US08301265B2
公开(公告)日：2012-10-30
申请号：US11852766
申请日：2007-09-10
申请人： Warren L. Starkebaum
发明人： Warren L. Starkebaum
IPC分类号： A61N1/00
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/0509 , A61N1/0558 , A61N1/36007 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： The invention is directed toward stimulation of a selected tissue layer. A device is attached to a target tissue by applying vacuum pressure to a vacuum cavity of the device and advancing a needle into tissue within the vacuum cavity. The depth on the vacuum cavity is selected to permit deployment at the selected tissue layer. In one embodiment, the invention is directed toward an implantable medical device comprising a device housing defining a vacuum cavity, and a vacuum port for application of vacuum pressure to draw tissue into the vacuum cavity, an electrode that is movable into the vacuum cavity of the device housing to contact at least a portion of the tissue drawn into the vacuum cavity, and a lead comprising at least one conductor coupled to the electrode.
摘要翻译：本发明涉及刺激所选择的组织层。通过将真空压力施加到装置的真空腔并将针推进到真空腔内的组织中，将装置附接到目标组织。选择真空腔上的深度以允许在选定的组织层处展开。在一个实施例中，本发明涉及可植入医疗装置，其包括限定真空腔的装置壳体和用于施加真空压力以将组织拉入真空腔的真空端口，可移动到真空腔的真空腔中的电极装置外壳以接触被抽吸到真空腔中的组织的至少一部分，以及包括至少一个连接到电极的导体的引线。

62. 发明申请

US20110224768A1 SURGICAL WEIGHT CONTROL SYSTEMS AND METHODS 失效
标题翻译：手术重量控制系统和方法
公开(公告)号：US20110224768A1
公开(公告)日：2011-09-15
申请号：US13114146
申请日：2011-05-24
申请人： STUART D. EDWARDS
发明人： STUART D. EDWARDS
IPC分类号： A61N1/00
CPC分类号： A61F5/0026 , A61B18/1485 , A61B18/1492 , A61B2018/00029 , A61B2018/00065 , A61B2018/00214 , A61B2018/00232 , A61B2018/00238 , A61B2018/00261 , A61B2018/00482 , A61B2018/00654 , A61B2018/00797 , A61B2018/1467 , A61B2218/002 , A61B2218/007 , A61M25/1011 , A61M2025/105 , A61M2210/1053 , A61N1/0509 , A61N1/06 , A61N1/36007 , A61N1/36014
摘要： An obesity treatment system has a first treatment region sized and configured for deployment in a duodenum and a second treatment region sized and configured for deployment in a stomach. The first and second treatment regions are spaced apart a distance sized and configured to permit simultaneous deployment of the first treatment region in the duodenum and deployment of the second treatment region in the stomach. The first and second treatment regions each carry at least one electrode, which can deliver energy to ablate tissue in and the duodenum.
摘要翻译：肥胖症治疗系统具有第一治疗区域，其尺寸和构造用于部署在十二指肠中，第二治疗区域的尺寸和构造适于部署在胃中。第一和第二治疗区域间隔一定距离，其尺寸和构造允许在十二指肠中同时部署第一治疗区域并且部署第二治疗区域在胃中。第一和第二处理区域各自携带至少一个电极，其可以传送能量以消融十二指肠内的组织和十二指肠。

63. 发明授权

US08019422B2 Gastric device and endoscopic delivery system 有权
标题翻译：胃装置和内镜递送系统
公开(公告)号：US08019422B2
公开(公告)日：2011-09-13
申请号：US11281049
申请日：2005-11-16
申请人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake
发明人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake
IPC分类号： A61N1/18
CPC分类号： A61B5/6882 , A61B5/4238 , A61B17/3421 , A61B17/3478 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00477 , A61B2017/306 , A61B2017/3488 , A61F5/0003 , A61M25/02 , A61M2025/0233 , A61M2025/028 , A61N1/0509 , A61N1/0517 , A61N1/36007 , A61N1/372 , G01N27/126 , G06F19/00
摘要： A system is provided for endoscopically attaching a functional device to a stomach wall wherein the functional device is configured to perform a therapeutic or diagnostic function at the stomach.
摘要翻译：提供了一种用于将功能装置内窥镜地附接到胃壁的系统，其中功能装置构造成在胃处执行治疗或诊断功能。

64. 发明申请

US20110087337A1 APPARATUS FOR CONTROLLING FLOW IN A BODILY ORGAN 有权
标题翻译：控制一个机器人流动的装置
公开(公告)号：US20110087337A1
公开(公告)日：2011-04-14
申请号：US12758684
申请日：2010-04-12
申请人： Peter FORSELL
发明人： Peter FORSELL
IPC分类号： A61N1/36 , A61N1/05 , A61N1/08 , A61F2/04 , A61F7/12 , A61F6/20
CPC分类号： A61B17/12 , A61F2/0036 , A61F2/004 , A61F7/02 , A61F2002/045 , A61F2250/0002 , A61N1/0509 , A61N1/0551 , A61N1/36007 , A61N1/36564 , A61N1/36578 , A61N1/403
摘要： An apparatus for controlling a flow of fluid and/or other bodily matter in a lumen formed by a tissue wall of a patient's organ comprises an implantable constriction device for gently constricting (i.e. without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the flow in the lumen, and a stimulation device for stimulating the wall portion of the tissue wall. A control device controls the stimulation device to stimulate the wall portion, as the constriction device constricts the wall portion, to cause contraction of the wall portion constricted by the constriction device to further influence the flow in the lumen. The apparatus can be used for restricting or stopping the flow in the lumen, or for actively moving the fluid in the lumen, with a low risk of injuring the organ. Such an organ may be the esophagus, stomach, intestines, urine bladder, urethra, ureter, renal pelvis, aorta, corpus cavernosum, exit veins of erectile tissue, uterine tube, vas deference or bile duct, or a blood vessel.
摘要翻译：用于控制由患者器官的组织壁形成的内腔中的流体和/或其他身体物质的流动的装置包括用于轻轻收缩（即基本上不妨碍组织壁内的血液循环）的可植入收缩装置至少一个组织壁的部分以影响管腔中的流动，以及用于刺激组织壁的壁部分的刺激装置。当收缩装置收缩壁部分时，控制装置控制刺激装置刺激壁部分，以引起由收缩装置收缩的壁部分的收缩，以进一步影响内腔中的流动。该装置可以用于限制或停止内腔中的流动，或用于主动地移动内腔中的流体，并且以较低的器官损伤风险。这样的器官可以是食道，胃，肠，尿膀胱，尿道，输尿管，肾盂，主动脉，海绵体，勃起出血组织，子宫管，血管或胆管或血管。

65. 发明申请

US20100305656A1 Gastric Simulation Anchor and Method 审中-公开
标题翻译：胃模拟锚和方法
公开(公告)号：US20100305656A1
公开(公告)日：2010-12-02
申请号：US12795389
申请日：2010-06-07
申请人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman
发明人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/36007 , A61B5/4238 , A61B5/6882 , A61B17/3421 , A61B17/3478 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00477 , A61B2017/306 , A61B2017/3488 , A61F5/0003 , A61M25/02 , A61M2025/0233 , A61M2025/028 , A61N1/0509 , A61N1/0517 , A61N1/372 , G01N27/126
摘要： A device, system and method for electrically stimulating the stomach is provided. A device system and method for attaching a stimulating device to the stomach wall is also provided.
摘要翻译：提供了用于电刺激胃的装置，系统和方法。还提供了一种用于将刺激装置附接到胃壁的装置系统和方法。

66. 发明授权

US07778704B2 Electrical stimulation of the sympathetic nerve chain 有权
标题翻译：电刺激交感神经链
公开(公告)号：US07778704B2
公开(公告)日：2010-08-17
申请号：US10495766
申请日：2002-10-23
申请人： Ali Rezai
发明人： Ali Rezai
IPC分类号： A61N1/365
CPC分类号： A61N1/0553 , A61N1/05 , A61N1/0509 , A61N1/326 , A61N1/36007 , A61N1/36017 , A61N1/36021 , A61N1/36071
摘要： The present invention provides a method of affecting physiological disorders by stimulating a specific location along the sympathetic nerve chain. Preferably, the present invention provides a method of affecting a variety of physiological disorders or pathological conditions by placing an electrode adjacent to or in communication with at least one ganglion along the sympathetic nerve chain and stimulating the at least one ganglion until the physiological disorder or pathological condition has been affected.
摘要翻译：本发明提供通过刺激交感神经链的特定位置来影响生理障碍的方法。优选地，本发明提供了通过将电极与交感神经链邻近或与至少一个神经节连通并且与至少一个神经节连通并刺激至少一个神经节直到生理障碍或病理学的方式来影响多种生理紊乱或病理状况的方法情况受到影响

67. 发明申请

US20100094373A1 METHOD AND APPARATUS FOR STIMULATING THE VASCULAR SYSTEM 审中-公开
标题翻译：用于刺激血管系统的方法和装置
公开(公告)号：US20100094373A1
公开(公告)日：2010-04-15
申请号：US12575713
申请日：2009-10-08
申请人： Virender K. Sharma
发明人： Virender K. Sharma
IPC分类号： A61N1/36
CPC分类号： A61N1/36007 , A61N1/0509 , A61N1/36 , A61N1/36114 , A61N1/36117
摘要： The present invention provides methods of treating a gastrointestinal condition. In some embodiments, the method generally includes administering a chemical or electrical stimulus to an artery of the gastrointestinal vasculature of the subject, a vein of the gastrointestinal vasculature of the subject, a nerve supplying an artery of the gastrointestinal vasculature of the subject, and/or a nerve supplying a vein of the gastrointestinal vasculature of the subject, wherein the chemical or electrical stimulus is effective for treating a gastrointestinal condition.
摘要翻译：本发明提供治疗胃肠道病症的方法。在一些实施方案中，该方法通常包括向受试者的胃肠脉管系统的动脉施用化学或电刺激，受试者的胃肠脉管系统的静脉，供应受试者的胃肠脉管系统的动脉的神经和/ 或供应受试者的胃肠脉管系统静脉的神经，其中所述化学或电刺激对于治疗胃肠道病症是有效的。

68. 发明授权

US07590452B2 Endoscopic system for attaching a device to a stomach 有权
标题翻译：用于将装置附接到胃的内窥镜系统
公开(公告)号：US07590452B2
公开(公告)日：2009-09-15
申请号：US10888622
申请日：2004-07-09
申请人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake
发明人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake
IPC分类号： A61N1/02
CPC分类号： A61B5/6882 , A61B5/4238 , A61B17/3421 , A61B17/3478 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00477 , A61B2017/306 , A61B2017/3488 , A61F5/0003 , A61M25/02 , A61M2025/0233 , A61M2025/028 , A61N1/0509 , A61N1/0517 , A61N1/36007 , A61N1/372 , G01N27/126 , G06F19/00
摘要： A method for diagnosing and treating gastric disorders is provided. A functional device resides within the patient?s stomach and is secured to the stomach wall by an attachment device. The functional device may be a sensor for sensing various parameters of the stomach or stomach environment, or may be a therapeutic delivery device. The functional device in one embodiment provides a method for gastric electrical stimulation where stimulating electrodes are secured to the wall of the stomach by the attachment device or otherwise. A preferred device includes: at least one stimulating electrode in electrical contact with the stomach wall; an electronics unit containing the electronic circuitry of the device; and an attachment mechanism for attaching the device to the stomach wall. The functional devices may be programmed to respond to sensed information or signals. An endoscopic delivery system delivers the functional device through the esophagus and into the stomach where it is attached the stomach wall. The endoscopic instruments attach or remove the attachment devices and functional devices from the stomach and may be used to assist in determining the optimal attachment location.
摘要翻译：提供了一种用于诊断和治疗胃疾病的方法。功能性装置位于患者胃内，并通过附接装置固定在胃壁上。功能装置可以是用于感测胃或胃环境的各种参数的传感器，或者可以是治疗递送装置。一个实施例中的功能装置提供了一种用于胃电刺激的方法，其中刺激电极通过附接装置或其它方式固定到胃的壁。优选的装置包括：与胃壁电接触的至少一个刺激电极; 包含该装置的电子电路的电子单元; 以及用于将装置附接到胃壁的附接机构。功能设备可以被编程为响应感测的信息或信号。内窥镜递送系统通过食管将功能装置输送到胃中，在胃附着胃壁。内窥镜器械将附接装置和功能装置从胃附接或移除，并且可以用于帮助确定最佳的附接位置。

69. 发明申请

US20090222057A1 Gastrointestinal Anchor In Optimal Surface Area 有权
标题翻译：胃肠锚在最佳表面积
公开(公告)号：US20090222057A1
公开(公告)日：2009-09-03
申请号：US12435278
申请日：2009-05-04
申请人： Mir A. Imran
发明人： Mir A. Imran
IPC分类号： A61N1/36 , A61B17/00
CPC分类号： A61F5/0003 , A61B5/4238 , A61B5/6882 , A61B17/3421 , A61B17/3478 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00477 , A61B2017/306 , A61B2017/3488 , A61M25/02 , A61M2025/0233 , A61M2025/028 , A61N1/0509 , A61N1/0517 , A61N1/36007 , A61N1/372 , G01N27/126
摘要： A device, system and method for anchoring a device to a stomach is provided. The device may be, among other things, a sensor for sensing various parameters of the stomach or stomach environment, or may be a therapeutic delivery device. The anchor of the device is constructed to resist pull out forces. An anchor has an optimal weight to surface area ratio.
摘要翻译：提供了一种用于将装置固定到胃的装置，系统和方法。该装置可以是用于感测胃或胃环境的各种参数的传感器，或者可以是治疗递送装置。该装置的锚固件被构造成抵抗拉出力。锚具具有最佳的表面积重量比。

70. 发明申请

US20090187230A1 Method and apparatus for programming of autonomic neuromodulation for the treatment of obesity 审中-公开
标题翻译：用于治疗肥胖的自主神经调节的方法和装置
公开(公告)号：US20090187230A1
公开(公告)日：2009-07-23
申请号：US12291685
申请日：2008-11-12
申请人： Daniel J. Dilorenzo
发明人： Daniel J. Dilorenzo
IPC分类号： A61N1/36
CPC分类号： A61N1/36007 , A61B5/00 , A61B5/4035 , A61B5/4041 , A61B5/407 , A61B5/41 , A61B5/4238 , A61B5/4866 , A61N1/0509 , A61N1/37247
摘要： The present invention teaches methods and apparatus for user control and operation of physiological modulation, including neural and gastrointestinal modulation, for the purposes of treating several disorders, including obesity. This includes programming of neuromodulatory signal for the modulation of autonomic neural and neuromuscular modulators, used to modulate tissues, including the afferent neurons of the sympathetic nervous system to induce satiety and efferent neurons to modulate metabolism.
摘要翻译：本发明教导用于控制和操作生理调节的方法和装置，包括神经和胃肠调节，用于治疗包括肥胖在内的几种疾病。这包括用于调节自主神经和神经肌肉调节剂的神经调节信号的编程，其用于调节组织，包括交感神经系统的传入神经元以诱导饱腹感和传出神经元调节代谢。

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