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    • 64. 发明申请
    • Dispensing Apparatus
    • 点胶装置
    • US20070246041A1
    • 2007-10-25
    • US11587665
    • 2005-04-27
    • Richard Warby
    • Richard Warby
    • A61M15/00
    • A61M15/009A61M15/008A61M15/0081A61M15/0091A61M2205/0288A61M2205/3317A61M2205/8243A61M2206/14
    • A pressurised metered dose inhaler (1) comprising: a reservoir (2) for containing pressurised product, a valve (9) having an inlet (11) communicating with the reservoir and an outlet (14) through which product is dispensed in use, a piece of magnetisable material (5), an armature (8) extending into proximity with the valve, and an electromagnet (7) surrounding at least a portion of the armature. Wherein the armature is coupled to, or forms part of, the valve such that controlled energisation of the electromagnet causes the armature to be either attracted to or repelled from the piece of magnetisable material one or more times to operate the valve for a controlled time period to effect dispensation of a metered dose of pressurised product from the reservoir through the valve outlet.
    • 一种加压计量剂量吸入器(1),包括:用于容纳加压产品的储存器(2),具有与储存器连通的入口(11)的阀(9)和在使用中通过其分配产品的出口(14) 可磁化材料片(5),延伸到阀附近的电枢(8)以及围绕电枢的至少一部分的电磁体(7)。 其中电枢联接到阀门或形成阀的一部分,使得电磁体的受控通电使衔铁被吸引或者从可磁化材料排出一次或多次,以在可控制的时间段内操作阀门 以通过阀出口从储存器分配计量剂量的加压产品。
    • 66. 发明申请
    • Integrated nebulizer and particle dispersion chamber for nasal delivery of medicament to deep nasal cavity and paranasal sinuses
    • 集成雾化器和颗粒分散室,用于鼻腔输送药物到深鼻腔和鼻旁窦
    • US20070131224A1
    • 2007-06-14
    • US10570724
    • 2004-09-03
    • Marc Giroux
    • Marc Giroux
    • A61M11/00
    • A61M15/08A61M2206/14
    • Particular aspects provide a novel integrated nebulizer and particle dispersion chamber (12), and novel methods of using same. Preferably, the particle dispersion chamber (12) provides for delivery of a vortical flow of nebulized particles to the notrils. The inventive integrated nebulizer, delivery methods and breathing techniques allow for delivering medicament into the deep nasal cavity and paranasal sinuses of a user. Significantly, the inventive devices and methods allow for systemic and topical delivery of medicaments via the membranes of the nasal cavity and paranasal sinuses. Additional preferred embodiments provide complementary cartridge docking system that allows for user-specific nebulized drug delivery.
    • 具体方面提供了一种新型的一体化雾化器和颗粒分散室(12),以及使用它的新颖方法。 优选地,颗粒分散室(12)提供将雾化颗粒的涡旋流输送到该清洁体。 本发明的一体化雾化器,递送方法和呼吸技术允许将药物输送到使用者的深鼻腔和鼻旁窦。 重要的是,本发明的装置和方法允许通过鼻腔和鼻旁窦的膜全身和局部递送药物。 附加的优选实施例提供允许用户特异性雾化药物递送的补充盒对接系统。
    • 69. 发明申请
    • Drug delivery apparatus
    • 药物输送装置
    • US20050087189A1
    • 2005-04-28
    • US10992920
    • 2004-11-19
    • David CrockfordJohn Denyer
    • David CrockfordJohn Denyer
    • A61M11/00A61M11/06A61M15/00A61M16/00B05D7/14
    • A61M11/06A61M11/002A61M11/005A61M15/0018A61M15/008A61M15/0086A61M15/0088A61M15/009A61M2016/0021A61M2016/0024A61M2016/0036A61M2205/43A61M2206/14
    • A drug delivery apparatus comprising: a drug delivery device for selectively delivering drug-laden air or air not laden with the drug; a sensor for monitoring the breathing pattern of a patient; a controller arranged to control the drug delivery device to deliver drug-laden air in pulses which begin when the patient is monitored by the sensor to begin inhalation, the pulses having a duration which is adjusted by the controller on the basis of the monitored breathing pattern of the patient; a feedback indicator which indicates to a patient whether the monitored breathing pattern is effective for inhaling drug-laden air or not a dose calculator which calculates the dose delivered to the patient; and an indicator which indicates to the patient when a desired dose has been delivered, whereby the apparatus is configured to deliver the full amount of the desired dose in at least 80% of treatments.
    • 一种药物输送装置,包括:药物输送装置,用于选择性地输送不含药物的载药空气或空气; 用于监测患者的呼吸模式的传感器; 控制器,其布置成控制药物递送装置以脉冲传送载药的空气,当患者被传感器监测以开始吸入时,该脉冲具有由控制器基于所监测的呼吸模式调节的持续时间 的病人 反馈指示器,其向患者指示所监测的呼吸模式是否对吸入载药空气有效,而不是计算递送给患者的剂量的剂量计算器; 以及当所需剂量已经递送时向患者指示的指示器,由此该装置构造成在至少80%的治疗中递送所需剂量的全部量。