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61. 发明授权

US07066929B1 Selective photothermolysis 失效
标题翻译：选择性光热解
公开(公告)号：US07066929B1
公开(公告)日：2006-06-27
申请号：US10148740
申请日：1999-12-02
申请人： Zion Azar , Pinchas Shalev
发明人： Zion Azar , Pinchas Shalev
IPC分类号： A61B18/18
CPC分类号： A61B18/203 , A61B18/20 , A61B2017/0007 , A61B2017/00084 , A61B2017/00088 , A61B2018/00017 , A61B2018/00452 , A61B2018/00458 , A61B2018/00636 , A61B2018/1807 , A61B2018/208
摘要： Performing selective photothermolysis of sub-cutaneous tissue by using a plurality of beams of narrow band electro-magnetic radiation, where each of the beams have energy that is insufficient to heat the tissue that they strike to a temperature high enough to destroy such tissue, but by directing the individual beams to overlap at the target sufficient heat is generated to destroy the target tissue.
摘要翻译：通过使用多个窄带电磁辐射束来执行副皮肤组织的选择性光热解，其中每个光束具有不足以加热组织的能量，使得它们发射到足够高的温度以破坏这种组织，但是通过引导各个光束在目标处重叠，产生足够的热量以破坏目标组织。

62. 发明授权

US07022118B2 Medical energy irradiation apparatus 失效
标题翻译：医疗能量照射装置
公开(公告)号：US07022118B2
公开(公告)日：2006-04-04
申请号：US10180291
申请日：2002-06-27
申请人： Shigeki Ariura , Akira Sakaguchi , Shin Maki
发明人： Shigeki Ariura , Akira Sakaguchi , Shin Maki
IPC分类号： A61B18/20
CPC分类号： A61B1/00091 , A61B1/126 , A61B1/127 , A61B18/201 , A61B18/22 , A61B90/70 , A61B2017/00274 , A61B2018/00011 , A61B2018/00547 , A61B2018/00982 , A61B2018/208 , A61B2018/2283 , A61B2090/3937 , A61B2090/701 , G02B23/2476
摘要： To provide a medical energy irradiation apparatus which permits easy and accurate establishment of a site of tissues of a living body targeted for irradiation with energy, when doctors use the medical energy irradiation apparatus to perform a cure for a prostatic hyperplasia or the like. The doctors insert an applicator 110 of the medical energy irradiation apparatus to an urinary bladder 161 and fix an endoscope 135 near to an entrance of an urethra. In this arrangement, when observing with the endoscope (135), a seminal colliculas 144 observed through a side-observation window 130 is observed toward a lower part of an observed image (schematic diagram) displayed on a display unit, and a positioning marker 140 in an interior of the applicator is observed toward an upper part of an observed image. The doctors can accurately determine a position to be irradiated with laser light from positions of the seminal colliculas 144 and the positioning marker 140 observed, and a direction of irradiation with laser light from a position of a direction marker 142, respectively.
摘要翻译：为了提供医疗能量照射装置，其能够容易且准确地建立目标为能量照射的生物体的组织部位，医生使用医疗用能量照射装置进行前列腺增生等的治愈时。医生将医疗能量照射装置的施用器110插入到膀胱161中，并将内窥镜135固定在尿道入口附近。在这种布置中，当利用内窥镜（135）观察时，朝向显示在显示单元上的观察图像（示意图）的下部观察通过侧观察窗130观察到的精液菌落144，并且定位标记器140 在观察图像的上部观察到施用器的内部。医生可以准确地确定从被观察到的精液菌落144和定位标记物140的位置用激光照射的位置，以及分别从方向标记物142的位置照射激光的方向。

63. 发明申请

US20050143719A1 Multi-spot laser surgical apparatus and method 失效
标题翻译：多点激光手术器械及方法
公开(公告)号：US20050143719A1
公开(公告)日：2005-06-30
申请号：US10751041
申请日：2003-12-31
申请人： Robert Sink
发明人： Robert Sink
IPC分类号： A61B18/20
CPC分类号： A61B18/203 , A61B2018/00452 , A61B2018/20351 , A61B2018/2065 , A61B2018/208
摘要： An array of light beams is swept along a main scan direction and dithered in a sub-scan direction to generate a treatment pattern of spots. The array is elongated along the sub-scan direction and the dithering has a travel that is significantly less than the length of the array in the sub-scan direction.
摘要翻译：沿主扫描方向扫描光束阵列，并沿副扫描方向抖动以产生斑点的处理图案。阵列沿着副扫描方向是细长的，并且抖动具有明显小于在副扫描方向上的阵列的长度的行程。

64. 发明申请

US20030216719A1 Method and apparatus for treating skin using patterns of optical energy 审中-公开
标题翻译：用光学图案处理皮肤的方法和装置
公开(公告)号：US20030216719A1
公开(公告)日：2003-11-20
申请号：US10367582
申请日：2003-02-14
发明人： Len Debenedictis , George Voevodkin , Michael Black
IPC分类号： A61B018/18
CPC分类号： A61B5/444 , A61B5/0059 , A61B18/20 , A61B18/203 , A61B2017/00057 , A61B2018/00452 , A61B2018/20351 , A61B2018/205545 , A61B2018/2075 , A61B2018/208
摘要： A dermatological apparatus includes multiple light source and optical pathway connections. Each light source is capable of delivering an optical beam through its connected optical pathway to a targeted portion of a human skin. The dermatological apparatus also includes a control system to select and control the light sources to deliver multiple optical beams in a discontinuous pattern and a focusing element to focus the power of the delivered optical beams to multiple discrete treatment zones that are located up to 1.5 mm underneath an outer surface of the targeted portion. The discrete treatment zones have sizes in the range of 10 nullm to 1000 nullm.
摘要翻译：皮肤病学装置包括多个光源和光路连接。每个光源能够通过其连接的光学路径将光束传送到人皮肤的目标部分。皮肤病学装置还包括控制系统，用于选择和控制光源以递送不连续图案中的多个光束和聚焦元件，以将输送的光束的功率聚焦到位于下方1.5mm处的多个离散处理区目标部分的外表面。离散处理区的尺寸范围为10〜1000μm。

65. 发明授权

US06520959B1 Laser irradiation device and method for therapy of prostate gland by use thereof 失效
标题翻译：激光照射装置及其使用的前列腺治疗方法
公开(公告)号：US06520959B1
公开(公告)日：2003-02-18
申请号：US09282458
申请日：1999-03-31
申请人： Shigenobu Iwahashi , Shigeki Ariura , Shin Maki
发明人： Shigenobu Iwahashi , Shigeki Ariura , Shin Maki
IPC分类号： A61B1818
CPC分类号： A61N5/0601 , A61B2018/208 , A61B2018/2272
摘要： This invention concerns a lateral-irradiation type laser irradiation device which is capable of effectively irradiating a target site, particularly at a considerable deth, with a laser beam while infallibly and easily preventing normal tissue from injury/and a method for curing prostate gland by the use of the laser irradiation device. The laser irradiating device 1 moves either or both of the laser probes 3, 4 having the reflecting mirrors 32, 42 provided at the distal end parts of the optical fibers 31, 41 in the longitudinal direction of the sheath 2 so as to alter the interval between the reflecting mirrors 32, 42 and move the position at which the reflected laser beams are concentrated (condensed), namely the target position 5 moves, in the direction perpendicular to the longitudinal axis of the sheath 2. The method for the therapy of the prostate gland which comprises inserting the laser probes 3, 4 through the urogenital canal, suitably moving the target position 5 at which the laser beams are concentrated, irradiating the ailing site with the laser beams, and curing the ailing site by degeneration or necrosis.
摘要翻译：本发明涉及一种横向照射型激光照射装置，其能够以不可靠且容易地防止正常组织受伤的方式有效地用激光束照射目标部位，特别是相当大的deth，以及通过所述激光照射装置固定前列腺的方法使用激光照射装置。激光照射装置1使具有设置在光纤31,41的远端部的反射镜32,42的激光探针3,4中的任一个或两个沿护套的纵向移动 2，以便改变反射镜32和42之间的间隔，并且移动反射的激光束在垂直于护套2的纵向轴线的方向上集中（冷凝）的位置，即目标位置5移动的位置。用于治疗前列腺的方法，其包括将激光探针3,4穿过泌尿生殖道，适当地移动目标位置5，在该位置处，塞子束集中，用激光束照射困难部位，并通过退化或坏死来治愈困难部位。

66. 发明授权

US6162052A Medical laser handpiece 失效
标题翻译：医用激光手机
公开(公告)号：US6162052A
公开(公告)日：2000-12-19
申请号：US15435
申请日：1998-01-29
申请人： Shinji Kokubu
发明人： Shinji Kokubu
IPC分类号： A61B18/20 , A61B17/00 , A61B18/22 , A61C1/00 , A61C3/02 , A61B17/36 , A61N5/06
CPC分类号： A61C1/0046 , A61B18/22 , A61B2017/00026 , A61B2018/208
摘要： A laser handpiece is configured by a main body 13 and a laser probe 10 mounted on the tip end of the main body 13. The laser probe 10 has an emission fiber 12. A laser beam generated by a laser beam source is emitted from an emission end portion 22 of the emission fiber 12. The emission end portion 22 of the emission fiber 12 is formed into a circular conical shape. The laser beam emitted from the emission end portion 22 contains a first laser beam which is emitted in the axial direction of the emission fiber 22, and a second laser beam which is emitted in a ring-like shape in a radial direction of the emission fiber 12.
摘要翻译：激光手机由主体13和安装在主体13的前端的激光探头10构成。激光探头10具有发射光纤12.由激光束源产生的激光束从发射发射光纤12的端部22。发射光纤12的发射端部22形成为圆锥形。从发射端部22发射的激光束包含沿发射光纤22的轴向发射的第一激光束和沿发射光纤的径向发射成环状的第二激光束 12。

67. 发明授权

US6152918A Laser device with auto-piercing tip for myocardial revascularization procedures 失效
标题翻译：具有自动穿刺尖端的激光装置用于心肌血运重建手术
公开(公告)号：US6152918A
公开(公告)日：2000-11-28
申请号：US58387
申请日：1998-04-09
申请人： Henry N. Padilla , Richard L. Mueller , Stuart D. Harman
发明人： Henry N. Padilla , Richard L. Mueller , Stuart D. Harman
IPC分类号： A61B1/018 , A61B1/267 , A61B1/313 , A61B17/00 , A61B17/22 , A61B17/34 , A61B18/20 , A61B18/22 , A61B18/24 , A61B19/00 , A61B18/18
CPC分类号： A61B17/3403 , A61B18/22 , A61B18/24 , A61B2017/00172 , A61B2017/00247 , A61B2017/22074 , A61B2017/22075 , A61B2017/22077 , A61B2018/00291 , A61B2018/00392 , A61B2018/208 , A61B90/37
摘要： The apparatus for combined mechanical/laser myocardial revascularization of a human heart includes: inserting a mechanical piercing device and an elongated flexible lasing apparatus into the chest cavity of a patient; mechanically auto-piercing, micro-tearing or spreading the epicardium of the heart; and then lasing from beneath the epicardium through the myocardium. The apparatus is guided to an area exterior to a ventricle of the patient's heart, and the distal end of the energy delivery device such as an optical fiber apparatus is placed internal to the exterior wall of the heart through an opening which has been created by mechanically piercing, micro-tearing or spreading the epicardium, so that the myocardium and not the epicardium is irradiated with laser energy to allow passage of said energy delivery device such as an optical fiber distal end or said laser energy into the left ventricular cavity without causing a laser irradiation of the epicardium which might be a cause of operative bleeding and for better allowing the sealing of the epicardium after the apparatus is removed. The apparatus includes a hand-held device controllable by the physician having a removable distal head portion with an auto-piercing mechanism and can use a vacuum source to provide a suction force at the head portion. The auto-piercing mechanism is implemented by various ways such as a spring-biased actuating member in the TMR hand-held device and an electro-mechanical operated piercing mechanism. The hand-held TMR device with handle assembly can also be controlled by a computer to provide auto- sequencing of the auto-piercing needle mechanism and the laser firing with auto-fiber advancement.
摘要翻译：用于人体心脏联合机械/激光心肌血运重建的装置包括：将机械刺穿装置和细长的柔性激光装置插入患者的胸腔中; 机械自动穿刺，微撕裂或散布心脏的心外膜; 然后通过心肌从心外膜下射出。该装置被引导到患者心脏的心室的外部区域，并且诸如光纤装置的能量输送装置的远端通过已经通过机械产生的开口放置在心脏的外壁内部穿透，微裂或扩散心外膜，使得心肌而不是心外膜被激光能量照射，以允许所述能量输送装置如光纤远端或所述激光能量通过到左心室，而不引起心外膜的激光照射可能是手术出血的原因，并且在移除装置之后更好地允许密封心包膜。该装置包括由医师控制的手持式装置，其具有带有自动穿孔机构的可拆卸远端头部，并且可以使用真空源在头部提供吸力。自动穿孔机构通过各种方式实现，例如TMR手持装置中的弹簧偏压致动构件和机电操作的穿孔机构。具有手柄组件的手持式TMR装置还可以由计算机控制，以提供自动穿刺针机构的自动排序和使用自动纤维前进的激光烧制。

68. 发明授权

US5480396A Laser beam ophthalmological surgery method and apparatus 失效
标题翻译：激光束眼科手术方法及装置
公开(公告)号：US5480396A
公开(公告)日：1996-01-02
申请号：US352357
申请日：1994-12-09
申请人： Gabriel Simon , Cheng-Hao Huang
发明人： Gabriel Simon , Cheng-Hao Huang
IPC分类号： A61B18/20 , A61B17/00 , A61F9/007 , A61F9/01 , A61N5/06 , A61B17/36
CPC分类号： A61F9/008 , A61F9/00804 , A61B2017/00199 , A61B2018/208 , A61B2018/2085 , A61B2018/2095 , A61F2009/00844 , A61F2009/00872 , A61F2009/00897
摘要： A laser beam ophthalmological surgery method includes the steps of generating a laser beam and splitting the generated laser beam into multiple laser beams which are simultaneously focused onto a plurality of scanners. Each scanner in turn produces a predetermined scanning pattern focused on the cornea of a patient's eye to ablate the cornea tissue and with at least two beams simultaneously scanning and ablating the cornea tissue. Scanning is controlled from a central processing unit to perform the surgical procedure, removing a laser thickness of the cornea tissue to provide a safer and more predictable surgical procedure in the reshaping of the cornea. A laser ophthalmological surgery apparatus is provided which includes a laser generating a laser beam, a beam splitter for splitting the laser beam into a plurality of laser beams, and a plurality of scanners, each positioned for receiving one of the laser beams from the beam splitter and producing a predetermined scanning pattern from the laser beam and impinging the scanning pattern upon the cornea of a patient's eye.
摘要翻译：激光束眼科手术方法包括以下步骤：产生激光束并将生成的激光束分成多个同时聚焦到多个扫描仪上的激光束。每个扫描器又产生聚焦在患者眼睛的角膜上的预定扫描图案，以消融角膜组织，并且至少两个光束同时扫描和消融角膜组织。从中央处理单元控制扫描以执行外科手术，去除角膜组织的激光厚度，以在角膜重塑中提供更安全和更可预测的外科手术。提供了一种激光眼科手术装置，其包括产生激光束的激光，用于将激光束分成多个激光束的分束器，以及多个扫描器，每个扫描器定位成用于接收来自分束器并从激光束产生预定的扫描图案，并将扫描图案照射在患者眼睛的角膜上。

69. 发明公开

US20240366429A1 OPTHALMOLOGICAL IMAGING AND LASER DELIVERY DEVICE, SYSTEM AND METHODS 审中-公开
公开(公告)号：US20240366429A1
公开(公告)日：2024-11-07
申请号：US18671647
申请日：2024-05-22
申请人： PulseMedica Corp.
发明人： Nir Katchinskiy , Abdulhakem Elezzabi
IPC分类号： A61F9/008 , A61B18/20 , A61B34/00
CPC分类号： A61F9/008 , A61B34/25 , A61B2018/2025 , A61B2018/208 , A61F2009/00846 , A61F2009/00851 , A61F2009/00897
摘要： An ophthalmological device and system is described that allows the simultaneous imaging of an eye using both scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT). Further the device and system is capable of targeting and delivering a treatment laser for treatment of an eye condition.

70. 发明授权

US11980575B2 Multi-core fiber for a multi-spot laser probe 有权
公开(公告)号：US11980575B2
公开(公告)日：2024-05-14
申请号：US17411563
申请日：2021-08-25
申请人： Alcon Inc.
发明人： Chenguang Diao , Mark Harrison Farley , Alireza Mirsepassi , Ronald T. Smith , Dean Richardson
IPC分类号： A61F9/008 , A61B18/22 , A61B18/24 , A61B90/30 , G02B6/38 , A61B18/00 , A61B18/20 , G02B6/02 , G02B6/42
CPC分类号： A61F9/00821 , A61B18/22 , A61B18/24 , A61B90/30 , A61F9/008 , A61F9/00823 , G02B6/3843 , G02B6/3851 , G02B6/3885 , A61B2018/00779 , A61B2018/2025 , A61B2018/2065 , A61B2018/208 , A61B2018/2211 , A61B2018/2255 , A61B2018/2266 , A61B2018/2294 , A61B2090/306 , A61F2009/00863 , G02B6/02042 , G02B6/4206
摘要： The present disclosure relates to a multi-core optical fiber cable (MCF). In some embodiments, an MCF comprises a plurality of cores surrounded by a cladding and a coating surrounding the cladding, wherein a refractive index of one or more of the plurality of cores is greater than a refractive index of the cladding. The MCF further comprises a probe comprising a probe tip coupled with a distal end of the MCF and a lens located at a distal end of the probe tip. In some embodiments, the lens is configured to translate laser light from the distal end of the MCF to create a multi-spot pattern of laser beams on a target surface and a distal end of the MCF terminates at an interface with the lens.

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