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61. 发明申请

US20090306673A1 KIT AND METHOD FOR FIXATING A PROSTHESIS OR PART THEREOF AND/OR FILLING OSSEOUS DEFECTS 失效
标题翻译：用于固定预处理或其部分和/或填充OSSEOUS缺陷的套件和方法
公开(公告)号：US20090306673A1
公开(公告)日：2009-12-10
申请号：US12463038
申请日：2009-05-08
申请人： Pier Buma , Berend Willem Schreurs , Nicolaas Jacobus Joseph Verdonschot , Lucas Hubert Bernard Walschot , Thomas Johannes Josephus Hubertus Slooff , Willem Cornelis Van't Wout, SR.
发明人： Pier Buma , Berend Willem Schreurs , Nicolaas Jacobus Joseph Verdonschot , Lucas Hubert Bernard Walschot , Thomas Johannes Josephus Hubertus Slooff , Willem Cornelis Van't Wout, SR.
IPC分类号： A61B17/58 , A61F2/28 , A61B17/56
CPC分类号： A61F2/468 , A61B17/7095 , A61B17/8847 , A61B17/885 , A61F2/0077 , A61F2/30723 , A61F2/30749 , A61F2/30767 , A61F2/3094 , A61F2/34 , A61F2/36 , A61F2/3662 , A61F2/3676 , A61F2/4601 , A61F2002/2835 , A61F2002/30125 , A61F2002/30588 , A61F2002/3069 , A61F2002/30726 , A61F2002/3092 , A61F2002/4602 , A61F2002/4631 , A61F2002/4677 , A61F2002/4681 , A61F2220/0008 , A61F2230/0008 , A61F2310/00023 , A61F2310/00353 , A61F2310/00592 , A61F2310/00796 , A61F2310/00928 , A61L27/04 , A61L27/16 , A61L27/56 , C23C30/00 , C08L33/12
摘要： Kit of parts, comprising: a prosthesis or prosthesis part having at least one contact surface; metal granules having an internal porosity; bone cement; and further comprising titanium granules for use in a kit of parts, which granules preferably are osteoconductive, which granules preferably are coated with a coating from the group of osteoconductive or osteoinductive coatings, or coatings comprising bioceramic, bioglass or osteoconductive or osteoinductive molecules or fluids or cells.
摘要翻译：包括：包括：具有至少一个接触表面的假体或假体部分; 具有内部孔隙率的金属颗粒; 骨水泥; 并且还包含用于试剂盒的钛颗粒，所述颗粒优选是骨传导的，所述颗粒优选地涂覆有来自骨传导或骨诱导性涂层的涂层或包含生物陶瓷，生物玻璃或骨传导或骨诱导分子或流体的涂层，或细胞。

62. 发明申请

US20090292322A1 METHOD OF REHABILITATING AN ANULUS FIBROSIS 有权
标题翻译：治疗神经纤维化的方法
公开(公告)号：US20090292322A1
公开(公告)日：2009-11-26
申请号：US12430787
申请日：2009-04-27
申请人： Gregory H. Lambrecht
发明人： Gregory H. Lambrecht
IPC分类号： A61B17/56 , A61B17/84
CPC分类号： A61B5/1076 , A61B5/4514 , A61B17/0057 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/064 , A61B17/068 , A61B17/320016 , A61B17/320708 , A61B17/3468 , A61B17/70 , A61B17/7095 , A61B2017/00261 , A61B2017/00557 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/00867 , A61B2017/044 , A61B2017/0458 , A61B2017/0488 , A61B2017/0496 , A61B2017/0647 , A61B2017/22077 , A61B2017/320044 , A61B2017/3445 , A61B2090/061 , A61B2090/062 , A61F2/2846 , A61F2/30723 , A61F2/30907 , A61F2/441 , A61F2/442 , A61F2/4601 , A61F2/4611 , A61F2/4657 , A61F2002/2817 , A61F2002/30062 , A61F2002/30075 , A61F2002/30131 , A61F2002/30224 , A61F2002/30228 , A61F2002/30291 , A61F2002/30462 , A61F2002/30571 , A61F2002/30583 , A61F2002/30589 , A61F2002/30677 , A61F2002/30777 , A61F2002/30785 , A61F2002/4435 , A61F2002/444 , A61F2002/448 , A61F2002/4627 , A61F2002/4635 , A61F2002/4658 , A61F2002/4661 , A61F2002/4662 , A61F2210/0004 , A61F2210/0061 , A61F2210/0085 , A61F2220/0075 , A61F2230/0013 , A61F2230/0069 , A61F2230/0091 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00293 , A61F2310/00365 , A61F2310/0097 , A61F2310/00976
摘要： Systems for minimally invasive disc augmentation include an anulus augmentation component and a nucleus augmentation component. Both are suited for minimally invasive deployment. The nucleus augmentation component restores disc height and/or replaces missing nucleus pulposus. The anulus augmentation component shields weakened regions of the anulus fibrosis and/or resists escape of natural nucleus pulposus and/or the nucleus augmentation component. Methods and deployment devices are also disclosed. Methods of closing a defect in an anulus fibrosus of an intervertebral disc using a barrier are also provided.
摘要翻译：用于微创椎间盘增大的系统包括增厚组件和增强核组件。两者均适用于微创部署。核增强组件恢复椎间盘高度和/或替代缺失的髓核。增强瓣膜的组件屏蔽了纤维化的弱化区域和/或抵抗天然髓核和/或增强核组分的逃逸。还公开了方法和展开装置。还提供了使用屏障来闭合椎间盘纤维的缺陷的方法。

63. 发明申请

US20090264892A1 Methods, Materials and Apparatus for Treating Bone or Other Tissue 有权
标题翻译：方法，治疗骨或其他组织的材料和装置
公开(公告)号：US20090264892A1
公开(公告)日：2009-10-22
申请号：US12485101
申请日：2009-06-16
申请人： Mordechay Beyar , Oren Globerman , Abraham Domb , Ronen Shavit , Hila Wachsler-Avrahami
发明人： Mordechay Beyar , Oren Globerman , Abraham Domb , Ronen Shavit , Hila Wachsler-Avrahami
IPC分类号： A61B17/56
CPC分类号： A61B17/8852 , A61B17/7095 , A61B17/8805 , A61B17/8811 , A61B17/8816 , A61B17/8819 , A61B17/8822 , A61B17/8833 , A61B2017/00539 , A61B2017/00734 , A61L24/06 , A61L27/16 , A61L2400/06 , A61L2430/38 , B01F7/00416 , B01F15/00006 , B01F15/00058 , B01F15/00883 , B01F15/0279 , C08L33/10
摘要： A method of treating a vertebra, comprising: (a) accessing an interior of a vertebra; and (b) introducing a sufficient amount of artificial biocompatible material which does not set to a hardened condition in storage, into said bone, with sufficient force to move apart fractured portions of said bone.
摘要翻译：一种治疗椎骨的方法，包括：（a）进入椎骨内部; 和（b）以足够的力将足量的人造生物相容性材料引入到所述骨中，所述人造生物相容性材料不会被固定在所述骨中，所述人造生物相容性材料不会被硬化。

64. 发明申请

US20090247664A1 BONE TREATMENT SYSTEMS AND METHODS 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20090247664A1
公开(公告)日：2009-10-01
申请号：US12395532
申请日：2009-02-27
申请人： Csaba Truckai , Andrew Kohm , John Shadduck , Robert Luzzi
发明人： Csaba Truckai , Andrew Kohm , John Shadduck , Robert Luzzi
IPC分类号： A61L24/04 , A61K6/08
CPC分类号： A61L24/0094 , A61B17/7095 , A61B17/8822 , A61B17/8833 , A61B17/8836 , A61B2017/00022 , A61K31/78 , A61L24/001 , A61L24/0084 , A61L24/0089 , A61L24/06 , A61L27/46 , A61L27/50 , A61L2400/06 , A61L2430/02 , C08L33/12
摘要： The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.
摘要翻译：本公开内容涉及具有用于椎体成形术程序和其它骨成形术程序的延长工作时间的骨水泥制剂以及水泥注射器，其包括用于按需控制水泥粘度和流动参数的能量输送系统。骨水泥制剂可以包括具有至少一种单体和包含聚合物颗粒和过氧化苯甲酰（BPO））的非液体组分的液体组分。非液体组分可以进一步构造成允许BPO受控地暴露于液体单体，以便能够控制骨水泥组合物的粘度。

65. 发明授权

US07510579B2 Enhanced visibility materials for implantation in hard tissue 有权
标题翻译：增强植入硬组织的可见性材料
公开(公告)号：US07510579B2
公开(公告)日：2009-03-31
申请号：US09828539
申请日：2001-04-05
申请人： Howard Preissman
发明人： Howard Preissman
IPC分类号： A61F2/02 , A61F2/04
CPC分类号： A61B17/7095 , A61F2/28 , A61F2/30965 , A61F2/44 , A61F2/4601 , A61F2002/3008 , A61F2250/0098 , A61F2310/00293 , A61F2310/00329 , A61F2310/00353 , A61L24/001 , A61L27/50
摘要： An enhanced visibility composition for implantation from a remote source, so that the composition can be readily observed under fluoroscopy or other imaging techniques is disclosed. The compositions include a biocompatible matrix, such as a hard tissue implant material for example, and radiopaque particles mixed in the matrix. The radiopaque particles have a particle size between about 120μ and 2200μ, more preferably bout 350μ and 2200μ, even more preferably between about 450μ and 1600μ, and most preferably between about 570μ and 1150μ. Preferably the hard tissue implant and the radiopaque particles are formed or prepared in a slurry. Optionally, the enhanced visibility composition may further include additional radiopaque particles or contrast particles mixed in with the composition, which have a particle size between about 120μ and 350μ, preferably between about 120μ and 250μ.
摘要翻译：提供了用于从远程源植入的增强的可见性组合物，使得可以在荧光透视或其它成像技术下容易地观察组合物。组合物包括生物相容性基质，例如硬组织植入材料和混入基质中的不透射线颗粒。不透射线的颗粒的粒径为约120μm至2200μm，更优选为350μm和2200μm，甚至更优选为约450μm至1600μm，最优选为约570μm至1150μm。优选地，硬组织植入物和不透射线的颗粒在浆液中形成或制备。任选地，增强的可见性组合物可进一步包括与组合物混合的附加的不透射线颗粒或造影剂颗粒，其具有约120μm至350μm之间，优选约120μm至250μm的粒度。

66. 发明申请

US20080269766A1 INTRAVERTEBRAL REDUCTION DEVICE WITH RETENTION BALLS 审中-公开
标题翻译：带保持杆的减速装置
公开(公告)号：US20080269766A1
公开(公告)日：2008-10-30
申请号：US11741855
申请日：2007-04-30
申请人： Jeff R. Justis
发明人： Jeff R. Justis
IPC分类号： A61B17/58 , A61B17/00
CPC分类号： A61B17/025 , A61B17/7095 , A61B17/8858 , A61B2017/0256
摘要： An intravertebral reduction device is disclosed and can include a handle assembly and a shaft assembly extending from the handle assembly. The shaft assembly can be configured to create a space within a bone and deliver one or more retention balls to the space within the bone.
摘要翻译：公开了一种椎间还原装置，并且可以包括手柄组件和从手柄组件延伸的轴组件。轴组件可以构造成在骨内产生空间并将一个或多个保留球输送到骨内的空间。

67. 发明申请

US20080051800A1 Method and device for reducing susceptibility to fractures in vertebral bodies 审中-公开
$Method and device for reducing susceptibility to fractures in vertebral bodies$
标题翻译：降低椎体骨折易感性的方法和装置
公开(公告)号：US20080051800A1
公开(公告)日：2008-02-28
申请号：US11776368
申请日：2007-07-11
申请人： Robert Diaz , David Campbell
发明人： Robert Diaz , David Campbell
IPC分类号： A61B17/58
CPC分类号： A61B17/7095 , A61B17/7098 , A61K35/32 , A61K38/1875 , A61K2300/00
摘要： The invention provides a method and a device for administering bone matrix with or without additional bone growth enhancing agents, or administering one or more bone growth enhancing agents to the interior surface of an unfractured vertebral body to enhance bone growth and strength, thus reducing susceptibility of the vertebral body to subsequent fracture.
摘要翻译：本发明提供了一种用于给予骨基质的方法和装置，所述骨基质含有或不含有另外的骨生长增强剂，或者向未断裂的椎体的内表面施用一种或多种骨生长增强剂以增强骨生长和强度，从而降低椎体随后骨折。

68. 发明申请

US20080045952A1 ANNULUS-REINFORCING BAND 审中-公开
标题翻译：神经增强带
公开(公告)号：US20080045952A1
公开(公告)日：2008-02-21
申请号：US11752059
申请日：2007-05-22
申请人： Stephen Kuslich
发明人： Stephen Kuslich
IPC分类号： A61B17/56
CPC分类号： A61F2/442 , A61B17/7095 , A61B17/7098 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61F2002/2817 , A61F2002/2821 , A61F2002/2835 , A61F2002/30092 , A61F2002/302 , A61F2002/30563 , A61F2002/30677 , A61F2002/30678 , A61F2002/30841 , A61F2002/4435 , A61F2002/444 , A61F2002/4475 , A61F2002/4495 , A61F2002/4627 , A61F2002/4631 , A61F2002/4635 , A61F2210/0014 , A61F2230/0065 , A61F2310/00017 , A61F2310/00023 , A61F2310/00071 , A61F2310/00179
摘要： A pliable band or hoop that is flexible to normal handling, but cannot stretch circumferentially once it has reached the limits of its circumferential length. The band may have a structural portal to be used for filling, or it may simply be constructed of a fabric-like material that allows a fill tube to perforate its walls to allow for filling. In the latter case, the perforated wall tends to self-seal once the fill tube is withdrawn. The band may be flat or tubular in cross-section. However, unlike a balloon, the band does not require either a bottom or a top, as we found that a top and bottom are unnecessary when using a band or hoop to enclose material injected into a reamed out intervertebral space.
摘要翻译：一种柔韧的带或箍，其柔性至正常处理，但一旦达到其圆周长度的极限，则不能沿周向拉伸。带可以具有用于填充的结构入口，或者其可以简单地由织物状材料构成，其允许填充管穿透其壁以允许填充。在后一种情况下，一旦填充管被抽出，穿孔壁就趋于自密封。带可以是平坦的或管状的横截面。然而，与气球不同，乐队不需要底部或顶部，因为我们发现当使用乐队或箍围绕注射到椎间盘的空间中时，顶部和底部是不必要的。

69. 发明申请

US20070233250A1 SYSTEMS FOR TREATING BONE 审中-公开
标题翻译：治疗骨骼的系统
公开(公告)号：US20070233250A1
公开(公告)日：2007-10-04
申请号：US11672434
申请日：2007-02-07
申请人： John Shadduck
发明人： John Shadduck
IPC分类号： A61F2/44
CPC分类号： A61B17/7095 , A61B18/02 , A61B18/08 , A61B18/1206 , A61B2017/564
摘要： The present invention relates in certain embodiments to medical devices for treating vertebral compression fractures. In one embodiment, the invention relate to systems for introducing fill material into a vertebral body that slowly expands vertebral height without explosive balloon expansion as in kyphoplasty. The system provides a fill material that infills a vertebra without flowable bone cement as used in kyphoplasty and vertebropalsty procedures. Thus, the bone fill system prevents the possibility of extravasation of material into the spinal canal which occurs in a significant number of kyphoplasty and vertebropalsty procedures. An energy source can apply energy to a substantially rigid implant material in order to soften, melt, or fracture the implant material to infill a vertebral body.
摘要翻译：本发明在某些实施例中涉及用于治疗脊椎压缩性骨折的医疗装置。在一个实施例中，本发明涉及用于将填充材料引入椎体中的系统，该椎体缓慢地扩大脊椎高度而没有爆炸性气囊膨胀，如在椎体后凸成形术中。该系统提供填充椎体的填充材料，不需要可流动的骨水泥，如在脊柱后凸成形术和椎板植入术中使用的。因此，骨填充系统防止材料外渗到脊柱管中的可能性，其发生在大量的脊柱后凸成形术和椎间盘手术中。能量源可以将能量施加到基本上刚性的植入材料上，以便软化，熔化或折断植入材料以填充椎体。

70. 发明申请

US20070191964A1 Enhanced visibility materials for implantation in hard tissue 审中-公开
标题翻译：增强植入硬组织的可见性材料
公开(公告)号：US20070191964A1
公开(公告)日：2007-08-16
申请号：US11246967
申请日：2005-10-07
申请人： Howard Preissman
发明人： Howard Preissman
IPC分类号： A61F2/28 , A61B6/12
CPC分类号： A61L24/001 , A61B17/7095 , A61F2/28 , A61F2/30965 , A61F2/44 , A61F2/4601 , A61F2002/3008 , A61F2250/0098 , A61F2310/00293 , A61F2310/00329 , A61F2310/00353 , A61L27/50
摘要： An enhanced visibility composition for implantation from a remote source, so that the composition can be readily observed under fluoroscopy or other imaging techniques is disclosed. The compositions include a biocompatible matrix, such as a hard tissue implant material for example, and radiopaque tracer particles mixed in the matrix. The radiopaque tracer particles have a particle size between about 120μ and 2200μ, more preferably about 350μ and 2200μ, even more preferably between about 450μ and 1600μ, and most preferably between about 570μ and 1150μ. Preferably the hard tissue implant and the radiopaque tracer particles are formed or prepared in a slurry. Optionally, the enhanced visibility composition may further include additional radiopaque contrast particles mixed in with the composition, which have a particle size between about 120μ and 350μ, preferably between about 120μ and 250μ.
摘要翻译：提供了用于从远程源植入的增强的可见性组合物，使得可以在荧光透视或其它成像技术下容易地观察组合物。组合物包括生物相容性基质，例如硬组织植入材料，以及混合在基质中的不透射线示踪剂颗粒。不透射线的示踪剂颗粒具有约120μm至2200μm之间的粒径，更优选约350μm和2200μm，甚至更优选约450μm至1600μm，最优选约570μm至1150μm。优选地，硬组织植入物和不透射线的示踪剂颗粒在浆液中形成或制备。任选地，增强的可见性组合物还可以包括与组合物混合的附加的不透射线造影剂颗粒，其具有在约120μm至350μm之间，优选约120μm和250μm之间的粒度。

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