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61. 发明授权

US07678740B2 Avermectin and avermectin monosaccharide derivatives substituted in the 4″-or 4′-position having pesticidal properties 有权
标题翻译：在4“ - 或4”位取代的具有杀虫性的阿维菌素和阿维菌素单糖衍生物
公开(公告)号：US07678740B2
公开(公告)日：2010-03-16
申请号：US10543637
申请日：2004-01-30
申请人： Thomas Pitterna , Fiona Murphy Kessabi , Peter Maienfisch , Jerome Cassayre , Laura Quaranta , Pierre Jung
发明人： Thomas Pitterna , Fiona Murphy Kessabi , Peter Maienfisch , Jerome Cassayre , Laura Quaranta , Pierre Jung
IPC分类号： A01N25/26 , A01N43/02 , A01N43/04 , C07H17/08
CPC分类号： A01N43/90 , C07H17/08
摘要： What is described are a compound of the formula (I) Wherein U is —N(R2)OR3 or —N+(O−)═C(RE)RZ); n is 0 or 1; X—Y is —CH═CH— or —CH2—CH2—; R1 is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; R2 and R3 are, for example; independently from each other, —Q, —C(═O)—Z—Q or —CN; RZ and RE are, independently from each other, —Q, —C(═O)—Z—Q or —CN; or RZ and RE together are a three- to seven membered alkylene or alkenylene bridge, which is unsubstituted or mono- to tri-substituted; Z is a bond, O or —NR4—; Q is H, C1-C12alkyl, C2-C12alkenyl, C2-C12alkynyl, C3-C12-Cycloalkyl, C5-C12-cycloalkenyl, aryl, or heterocyclyl, which are unsubstituted or mono- to pentasubstituted; R4 is for example H, C1-C8alkyl, hydroxy-C1-C8alkyl, C3-C8cycloalkyl or C2-C8alkenyl; or, if appropriate, an E/Z isomer, E/Z isomer mixture and/or tautomer thereof; a process for preparing these compounds, their isomers and tautomers and the use of these compounds, their isomers and tautomers; pesticidal compositions whose active compound is selected from these compounds and their tautomers; intermediates for the preparation of the said compounds of the formula (I), methods for the preparation of the compounds of the formula (I), and a method for controlling pests using these compositions.
摘要翻译：描述的是式（I）的化合物，其中U是-N（R 2）OR 3或-N +（O-）= C（RE）R Z）; n为0或1; X-Y是-CH = CH-或-CH 2 -CH 2 - ; R1是C1-C12烷基，C3-C8环烷基或C2-C12链烯基; R2和R3例如是：独立地为-Q，-C（= O）-Z-Q或-CN; RZ和RE彼此独立地为-Q，-C（= O）-Z-Q或-CN; 或RZ和RE一起是三至七元的亚烷基或亚烯基桥，其是未取代的或一至三取代的; Z是O或-NR4-键; Q是未被取代或被一取代或五取代的H，C 1 -C 12烷基，C 2 -C 12烯基，C 2 -C 12炔基，C 3 -C 12环烷基，C 5 -C 12 - 环烯基，芳基或杂环基， R4是例如H，C1-C8烷基，羟基-C1-C8烷基，C3-C8环烷基或C2-C8链烯基; 或者，如果合适的话，E / Z异构体，E / Z异构体混合物和/或其互变异构体; 制备这些化合物，其异构体和互变异构体的方法以及这些化合物，其异构体和互变异构体的用途; 活性化合物选自这些化合物及其互变异构体的杀虫组合物; 用于制备所述式（I）化合物的中间体，式（I）化合物的制备方法和使用这些组合物来控制害虫的方法。

62. 发明授权

US07674474B2 Pesticidal agents on the basis of 1-aryl-aminopyrrol 有权
标题翻译：基于1-芳基 - 氨基吡咯的杀虫剂
公开(公告)号：US07674474B2
公开(公告)日：2010-03-09
申请号：US11615679
申请日：2006-12-22
申请人： David Chou , Werner Knauf , Michael Maier , Michael James Malaska , Don McIntyre , Friederike Lochhaas , Scot Kevin Huber
发明人： David Chou , Werner Knauf , Michael Maier , Michael James Malaska , Don McIntyre , Friederike Lochhaas , Scot Kevin Huber
IPC分类号： A01N43/36 , C07D207/36 , C07D401/02
CPC分类号： C07D207/36 , A01N43/36 , A01N43/40
摘要： Pesticidal Compounds The invention relates to 1-aryl-5-disubstituted-aminopyrrole derivatives of formula (I) or salts thereof: wherein the various symbols are as defined in the description, to processes for their preparation, to compositions thereof, and to their use for the control of pests (including arthropods and helminths).
摘要翻译：杀虫化合物本发明涉及式（I）的1-芳基-5-二取代 - 氨基吡咯衍生物或其盐：其中各种符号如说明书中所定义，其制备方法，组合物及其用途用于控制害虫（包括节肢动物和蠕虫）。

63. 发明授权

US07662961B2 N-phenylpyrazole derivatives as pesticides 有权
标题翻译： N-苯基吡唑衍生物作为农药
公开(公告)号：US07662961B2
公开(公告)日：2010-02-16
申请号：US11615668
申请日：2006-12-22
申请人： Stefan Schnatterer , Michael Maier , Friederike Lochhaas , Werner Knauf , Karl Seeger
发明人： Stefan Schnatterer , Michael Maier , Friederike Lochhaas , Werner Knauf , Karl Seeger
IPC分类号： C07D241/02 , C07D401/04 , C07D403/04
CPC分类号： C07D231/44
摘要： The invention relates to bis-5-pyrazolyl derivatives of formula (I) or salts thereof: wherein the various symbols are as defined in the description, to processes for their preparation, to compositions thereof, and to their use for the control of pests (including arthropods and helminths).
摘要翻译：本发明涉及式（I）的双-5-吡唑基衍生物或其盐：其中各种符号如说明书中所定义，其制备方法，组合物及其用于防治害虫的用途（包括节肢动物和蠕虫）。

64. 发明授权

US07655440B2 DNA molecules encoding ligand gated ion channels from Dermacentor variabilis 有权
标题翻译：编码来自Dermacentor variabilis的配体门控离子通道的DNA分子
公开(公告)号：US07655440B2
公开(公告)日：2010-02-02
申请号：US11840542
申请日：2007-08-17
申请人： Doris F. Cully , Yingcong Zheng
发明人： Doris F. Cully , Yingcong Zheng
IPC分类号： C12N15/00 , C12N15/85 , C12N5/06 , C07H21/04 , C07K14/00
CPC分类号： C07K14/43531 , C07K14/705
摘要： The present invention relates in part to isolated nucleic acid molecules (polynucleotides) which encode Dermacentor variabilis ligand gated ion channel proteins. The present invention also relates to recombinant vectors and recombinant hosts which contain a DNA fragment encoding D. variabilis LGIC/GluCl channels, substantially purified forms of associated D. variabilis channel proteins and recombinant membrane fractions comprising these proteins, associated mutant proteins, and methods associated with identifying compounds which modulate associated Dermacentor variabilis LGIC/GluCl, which will be useful as insecticides and acaracides.
摘要翻译：本发明部分涉及编码Dermacentor variabilis配体门控离子通道蛋白的分离的核酸分子（多核苷酸）。本发明还涉及含有编码变形杆菌LGIC / GluCl通道的DNA片段的重组载体和重组宿主，基本纯化形式的相关变异型通道蛋白和包含这些蛋白质，相关突变型蛋白质和相关方法的重组膜级分鉴定化合物，其调节可能作为杀虫剂和杀螨剂使用的相关Dermacentor variabilis LGIC / GluCl的化合物。

65. 发明授权

US07582302B2 Needle-free administration of FeLV vaccines 有权
标题翻译：无针管的FeLV疫苗
公开(公告)号：US07582302B2
公开(公告)日：2009-09-01
申请号：US11146299
申请日：2005-06-06
申请人： Tesfai Tseggai , Maria Camila Pardo , Alton Timothy Leard
发明人： Tesfai Tseggai , Maria Camila Pardo , Alton Timothy Leard
IPC分类号： A61K39/12 , A61K39/21 , A61K39/42 , A61K39/275 , C12P19/34 , C12N15/00 , C12N15/64
CPC分类号： A61K39/21 , A61K39/12 , A61K2039/54 , A61K2039/545 , A61M2250/00 , C07K14/005 , C12N2710/16643 , C12N2710/24043 , C12N2740/13022 , C12N2740/13034
摘要： The invention provides a novel method of vaccination of an animal of the felidae family against feline leukemia. The FeLV recombinant vaccine based on viral vector with the aid of a liquid jet needle-free injector can result in distribution of the vaccine essentially in the dermis and the hypodermis of the animal.
摘要翻译：本发明提供了一种针对猫白血病疫苗接种fellidae家族的动物的新方法。基于病毒载体的FeLV重组疫苗借助于液体射针无针注射器可导致疫苗基本上分布在动物的真皮和皮下组织中。

66. 发明授权

US07563773B2 Anthelmintic oral homogeneous veterinary pastes 有权
标题翻译：驱虫药口服同类兽药
公开(公告)号：US07563773B2
公开(公告)日：2009-07-21
申请号：US11107048
申请日：2005-04-15
申请人： Keith Freehauf , Maryam Moaddeb
发明人： Keith Freehauf , Maryam Moaddeb
IPC分类号： A01N43/04 , A61K31/70 , A61K31/495
CPC分类号： A61K31/498 , A61K9/0056 , A61K31/7048 , A61K2300/00
摘要： This invention provides for, inter alia, oral homogeneous veterinary pastes for the treating, controlling and preventing of endo- and ectoparasite infections in warm-blooded animals or birds, such as horses and household pets. This invention further provides for a process of preparing these veterinary pastes and for a method for increasing the bioavailability of the anthelmintic agents contained in the paste in the warm-blooded animal or bird. The inventive oral homogeneous anthelmintic pastes comprise a first anthelmintic agent, for example, prazequantel and/or pyrantel, and at least one marcrolide anthelmintic compound, a solvent, which dissolves both the first anthelmintic agent and second the macrolide anthelmintic compound, and a thickening agent. The inventive oral homogeneous pastes achieve a better bioavailability of the two active anthelmintic agents than when the two actives are in suspension and not dissolved
摘要翻译：本发明特别提供了用于治疗，控制和预防温血动物或鸟类如马和家庭宠物中的内寄生虫和外寄生虫感染的口腔同质兽药。本发明进一步提供了制备这些兽用糊剂的方法和用于增加包含在温血动物或鸟类中的糊剂中的驱肠剂的生物利用度的方法。本发明的口腔均匀驱肠药膏包括第一驱肠虫剂，例如赞夸酮和/或吡柔比星，以及至少一种扑灭姜黄素的驱肠虫化合物，溶解第一驱肠虫剂和第二大环内酯类驱虫剂化合物的溶剂，以及增稠剂。与两种活性物质悬浮并不溶解时相比，本发明的口服均质膏实现了两种活性驱肠虫剂的更好的生物利用度

67. 发明授权

US07541432B2 L-glutamate-gated chloride channel proteins from Rhipicephalus sanguineus 有权
标题翻译：来自Rhipicephalus sanguineus的L-谷氨酸氯化物通道蛋白
公开(公告)号：US07541432B2
公开(公告)日：2009-06-02
申请号：US11620347
申请日：2007-01-05
申请人： Jeffrey W. Warmke , Youfeng Yang , Doris F. Cully , Michel J. Hamelin
发明人： Jeffrey W. Warmke , Youfeng Yang , Doris F. Cully , Michel J. Hamelin
IPC分类号： C07K14/00 , C12N15/63 , C12N5/16 , C12N1/19
CPC分类号： C07K14/43527 , C07K14/705 , G01N33/6872 , G01N2333/43556
摘要： The present invention relates in part to isolated nucleic acid molecules (polynucleotides) which encode Rhipicephalus sanguineus glutamate gated chloride channels. The present invention also relates to recombinant vectors and recombinant hosts which contain a DNA fragment encoding R. sanguineus glutamate gated chloride channels, substantially purified forms of associated R. sanguineus glutamate gated chloride channels and recombinant membrane fractions comprising these proteins, associated mutant proteins, and methods associated with identifying compounds which modulate associated Rhipicephalus sanguineus glutamate gated chloride channels, which will be useful as insecticides.
摘要翻译：本发明部分涉及编码Rigicephalus sanguineus glutamate门控氯化物通道的分离的核酸分子（多核苷酸）。本发明还涉及重组载体和重组宿主，其含有编码雷神酵母谷氨酸盐门控氯化物通道的DNA片段，基本上纯化形式的相关的谷氨酸谷氨酸盐化氯化物通道和包含这些蛋白质的重组膜级分，相关突变蛋白质，和与鉴定调节相关联的Rhipicephalus sanguineus glutamate门控氯化物通道的化合物相关的方法，其将用作杀虫剂。

68. 发明授权

US07531186B2 Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz 有权
标题翻译：包含1-N-芳基吡唑衍生物和氨基拉唑的局部制剂
公开(公告)号：US07531186B2
公开(公告)日：2009-05-12
申请号：US10783459
申请日：2004-02-20
申请人： Albert Boeckh , Luiz Gustavo Cramer , Mark D. Soll
发明人： Albert Boeckh , Luiz Gustavo Cramer , Mark D. Soll
IPC分类号： A01N25/32
CPC分类号： A01N43/56 , A01N47/02 , A01N2300/00 , A01N37/52
摘要： The present invention provides for, inter alia, novel topical formulations comprising at least one 1-N-arypyrazole derivative and amitraz and to methods for treating, controlling, or preventing parasite infestations on mammals or birds The inventive formulations include spot-on, pour-on or spray formulations and may include a further ectoparasiticide, such as an IGR compound, an avermectin or milbemycin derivative, or a pyrethroid insecticides, and anthelmintics, such as benzimidazoles and imidazothiazoles. The inventive formulation provides a larger duration of parasite control at a faster rate of control. The inventive formula remains effective up to three months from the first application. Moreover, the inventive formulations prevent tick attachment to the animal, thereby providing protection against tick borne diseases. The ectoparasites which may be controlled, treated or prevented by the present invention includes ticks, fleas, mites, mange, lice, mosquitoes, flies and cattle grubs.
摘要翻译：本发明特别提供了包含至少一种1-N-阿吡唑衍生物和氨喋啶的新型局部制剂，以及用于治疗，控制或预防哺乳动物或鸟类寄生虫侵袭的方法。本发明的制剂包括点状，可以包括另外的外寄生物杀虫剂，例如IGR化合物，除虫菌素或米尔倍霉素衍生物，拟除虫菊酯杀虫剂，以及驱肠虫药如苯并咪唑和咪唑并噻唑。本发明的配方以更快的控制速率提供更大的寄生虫控制持续时间。本发明的公式从第一次申请至多三个月仍然有效。此外，本发明的制剂防止蜱附着于动物，从而提供防止蜱携带疾病的保护。本发明可以控制，治疗或预防的外寄生虫包括蜱，跳蚤，螨虫，虱子，虱子，蚊子，苍蝇和牛。。。

69. 发明授权

US07531182B2 Vaccine against foot-and-mouth disease 有权
标题翻译：疫苗针对口蹄疫
公开(公告)号：US07531182B2
公开(公告)日：2009-05-12
申请号：US10327481
申请日：2002-12-20
申请人： Andrew Maurice Quatermain King , Alison Jane Burman , Jean-Christophe Francis Audonnet , Michel Francois Antoine Lombard
发明人： Andrew Maurice Quatermain King , Alison Jane Burman , Jean-Christophe Francis Audonnet , Michel Francois Antoine Lombard
IPC分类号： A61K39/135 , A61K39/235 , A61K39/245 , A61K39/275 , A61K39/285
CPC分类号： C07K14/005 , A61K39/12 , A61K39/135 , A61K2039/5258 , A61K2039/53 , A61K2039/552 , A61K2039/55522 , C12N2710/24143 , C12N2770/32122 , C12N2770/32134
摘要： A vaccine against foot-and-mouth disease, using as antigen an efficient amount of empty capsids of the foot-and-mouth virus. The empty capsids are obtained by expressing, in eukaryotic cells, cDNA of the P1 region of the foot-and-mouth virus genome coding for the capsid and cDNA of the region of the foot-and-mouth virus genome coding for protease 3C. The vaccine further includes a carrier or excipient pharmaceutically acceptable in veterinary medicine.
摘要翻译：一种针对口蹄疫的疫苗，作为抗原使用有效量的口蹄疫病毒空衣壳。通过在真核细胞中表达编码针对蛋白酶3C的口蹄疫病毒基因组区域的衣壳和cDNA的口蹄疫病毒基因组的P1区的cDNA，获得空的衣壳。该疫苗还包括兽药中药学上可接受的载体或赋形剂。

70. 发明授权

US07514561B2 Pesticidal 5-(acylamino) pyrazole derivatives 有权
标题翻译：杀虫剂5-（酰氨基）吡唑衍生物
公开(公告)号：US07514561B2
公开(公告)日：2009-04-07
申请号：US10537547
申请日：2003-11-12
申请人： Stefan Schnatterer , David William Hawkins , Daniela Jans , Michael Maier , Anke Kuhlmann , Erich Friedrich Sanwald , Maria-Theresia Thönessen , Karl Seeger
发明人： Stefan Schnatterer , David William Hawkins , Daniela Jans , Michael Maier , Anke Kuhlmann , Erich Friedrich Sanwald , Maria-Theresia Thönessen , Karl Seeger
IPC分类号： A61K31/4439 , A61K31/4152 , C07D231/28
CPC分类号： C07D401/12 , A01N43/56 , C07D231/44
摘要： Substituted-acylaminopyrazole derivatives of formula (I): or salts thereof, wherein the various symbols are as defined in the description, processes for their preparation, compositions thereof and methods for their use for the control of pests, such as arthropods (e.g. insects and arachnids) and helminths (including nematodes).
摘要翻译：式（I）的取代的酰基氨基吡唑衍生物或其盐，其中各种符号如说明书中所定义，其制备方法，组合物及其用于控制害虫的方法，例如节肢动物（例如昆虫和蛛形纲）和蠕虫（包括线虫）。

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