专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

61. 发明授权

US08480866B2 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 有权
公开(公告)号：US08480866B2
公开(公告)日：2013-07-09
申请号：US12930919
申请日：2011-01-20
申请人： Shoji Miyazaki , Eriko Yamanishi
发明人： Shoji Miyazaki , Eriko Yamanishi
IPC分类号： G01N27/327
CPC分类号： G01N27/3272 , C12Q1/001 , G01N33/48771 , Y10T29/49002
摘要： A biosensor is disclosed comprising a support; a conductive layer composed of an electrical conductive material such as a noble metal, for example gold or palladium, and carbon; slits parallel to and perpendicular to the side of the support; working, counter, and detecting electrodes; a spacer which covers the working, counter, and detecting electrodes on the support; a rectangular cutout in the spacer forming a specimen supply path; an inlet to the specimen supply path; a reagent layer formed by applying a reagent containing an enzyme to the working, counter, and detecting electrodes, which are exposed through the cutout in the spacer; and a cover over the spacer. The biosensor can be formed by a simple method, and provides a uniform reagent layer on the electrodes regardless of the reagent composition.

62. 发明申请

US20130020208A1 METHOD OF MEASURING QUANTITY OF SUBSTRATE 审中-公开
标题翻译：测量基板数量的方法
公开(公告)号：US20130020208A1
公开(公告)日：2013-01-24
申请号：US13609305
申请日：2012-09-11
申请人： Shoji Miyazaki , Hiroyuki Tokunaga , Yoshinobu Tokuno , Kazuhiro Matsumoto , Yasuhiko Sawada
发明人： Shoji Miyazaki , Hiroyuki Tokunaga , Yoshinobu Tokuno , Kazuhiro Matsumoto , Yasuhiko Sawada
IPC分类号： G01N27/327
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
摘要翻译：提供了测量样品液体中所含的基板的量的方法。该方法可以减少由生物传感器引起的测量误差。生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源通过连接端子对各个电极施加电压。只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二由驱动电源施加电压引起的连接端子。

63. 发明授权

US08142629B2 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 有权
标题翻译：生物传感器，薄膜电极形成方法，定量装置和定量方法
公开(公告)号：US08142629B2
公开(公告)日：2012-03-27
申请号：US12802573
申请日：2010-06-09
申请人： Shoji Miyazaki , Hiroyuki Tokunaga , Masaki Fujiwara , Eriko Yamanishi , Yoshinobu Tokuno
发明人： Shoji Miyazaki , Hiroyuki Tokunaga , Masaki Fujiwara , Eriko Yamanishi , Yoshinobu Tokuno
IPC分类号： G01N27/327
CPC分类号： G01N27/3272 , C12Q1/001 , G01N33/48771 , Y10T29/49002
摘要： A biosensor according to the present invention comprises a support 1, a conductive layer 2 composed of an electrical conductive material such as noble metal, for example gold, palladium or the like, and carbon, slits 3a and 3b parallel to the side of the support 1, slits 4a and 4b vertical to the side of the support 1, a working electrode 5, a counter electrode 6, a detecting electrode 7, a spacer 8 which covers the working electrode 5, the counter electrode 6 and the detecting electrode 7 on the support 1, a rectangular cutout part 9 forming a specimen supply path, an inlet 9a of the specimen supply path, a reagent layer 12 formed by applying a reagent including an enzyme or the like to the working electrode 5, the counter electrode 6 and the detecting electrode 7, which is exposed from the cutout part 9 of the spacer 8, and a cover 13 which covers the spacer 8, as shown in FIG. 1. The so-constructed biosensor can be formed by a simple method, and a biosensor which is excellent in a measuring accuracy as well as a biosensor in which a reagent layer is placed uniformly on the electrodes regardless of a reagent liquid composition, and which has a uniform performance can be realized.
摘要翻译：根据本发明的生物传感器包括支撑体1，由诸如金，钯等的诸如贵金属的导电材料构成的导电层2和碳，平行于载体侧的狭缝3a和3b 如图1所示，与支撑体1侧垂直的狭缝4a，4b，工作电极5，对电极6，检测电极7，覆盖工作电极5的间隔件8，对置电极6和检测电极7 支撑体1，形成试样供给路径的矩形切口部9，试料供给路径的入口9a，通过将包含酶等的试剂涂布在工作电极5上而形成的试剂层12，对电极6和从间隔件8的切口部9暴露的检测电极7和覆盖间隔件8的盖13，如图1所示。如此构造的生物传感器可以通过简单的方法形成，并且测量精度优异的生物传感器以及试剂层均匀地放置在电极上而不考虑试剂液体组成的生物传感器，并且其中具有统一的性能可以实现。

64. 发明申请

US20110272296A1 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 有权
公开(公告)号：US20110272296A1
公开(公告)日：2011-11-10
申请号：US13135816
申请日：2011-07-15
申请人： Shoji Miyazaki , Hiroyuki Tokunaga , Masaki Fujiwara , Eriko Yamanishi , Yoshinobu Tokuno
发明人： Shoji Miyazaki , Hiroyuki Tokunaga , Masaki Fujiwara , Eriko Yamanishi , Yoshinobu Tokuno
IPC分类号： G01N27/26 , G01N33/50
CPC分类号： G01N27/3272 , C12Q1/001 , G01N33/48771 , Y10T29/49002
摘要： A biosensor according to the present invention comprises a support 1, a conductive layer 2 composed of an electrical conductive material such as noble metal, for example gold, palladium or the like, and carbon, slits 3a and 3b parallel to the side of the support 1, slits 4a and 4b vertical to the side of the support 1, a working electrode 5, a counter electrode 6, a detecting electrode 7, a spacer 8 which covers the working electrode 5, the counter electrode 6 and the detecting electrode 7 on the support 1, a rectangular cutout part 9 forming a specimen supply path, an inlet 9a of the specimen supply path, a reagent layer 12 formed by applying a reagent including an enzyme or the like to the working electrode 5, the counter electrode 6 and the detecting electrode 7, which is exposed from the cutout part 9 of the spacer 8, and a cover 13 which covers the spacer 8, as shown in FIG. 1. The so-constructed biosensor can be formed by a simple method, and a biosensor which is excellent in a measuring accuracy as well as a biosensor in which a reagent layer is placed uniformly on the electrodes regardless of a reagent liquid composition, and which has a uniform performance can be realized.

65. 发明申请

US20110147234A1 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 有权
公开(公告)号：US20110147234A1
公开(公告)日：2011-06-23
申请号：US12930957
申请日：2011-01-20
申请人： Shoji Miyazaki , Hiroyuki Tokunaga , Masaki Fujiwara , Eriko Yamanishi , Yoshinobu Tokuno
发明人： Shoji Miyazaki , Hiroyuki Tokunaga , Masaki Fujiwara , Eriko Yamanishi , Yoshinobu Tokuno
IPC分类号： G01N27/416
CPC分类号： G01N27/3272 , C12Q1/001 , G01N33/48771 , Y10T29/49002
摘要： A biosensor according to the present invention comprises a support 1, a conductive layer 2 composed of an electrical conductive material such as noble metal, for example gold, palladium or the like, and carbon, slits 3a and 3b parallel to the side of the support 1, slits 4a and 4b vertical to the side of the support 1, a working electrode 5, a counter electrode 6, a detecting electrode 7, a spacer 8 which covers the working electrode 5, the counter electrode 6 and the detecting electrode 7 on the support 1, a rectangular cutout part 9 forming a specimen supply path, an inlet 9a of the specimen supply path, a reagent layer 12 formed by applying a reagent including an enzyme or the like to the working electrode 5, the counter electrode 6 and the detecting electrode 7, which is exposed from the cutout part 9 of the spacer 8, and a cover 13 which covers the spacer 8, as shown in FIG. 1. The so-constructed biosensor can be formed by a simple method, and a biosensor which is excellent in a measuring accuracy as well as a biosensor in which a reagent layer is placed uniformly on the electrodes regardless of a reagent liquid composition, and which has a uniform performance can be realized.

66. 发明申请

US20100320097A1 Method of measuring quantity of substrate 有权
标题翻译：测量基材数量的方法
公开(公告)号：US20100320097A1
公开(公告)日：2010-12-23
申请号：US12803253
申请日：2010-06-22
申请人： Shoji Miyazaki , Hiroyuki Tokunaga , Yoshinobu Tokuno , Kazuhiro Matsumoto , Yasuhiko Sawada
发明人： Shoji Miyazaki , Hiroyuki Tokunaga , Yoshinobu Tokuno , Kazuhiro Matsumoto , Yasuhiko Sawada
IPC分类号： G01N27/26 , G01K1/00
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
摘要翻译：提供了测量样品液体中所含的基板的量的方法。该方法可以减少由生物传感器引起的测量误差。生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源通过连接端子对各个电极施加电压。只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二由驱动电源施加电压引起的连接端子。

67. 发明申请

US20080110754A1 Biosensor, measuring instrument for biosensor, and method of quantifying substrate 审中-公开
标题翻译：生物传感器，生物传感器的测量仪器和定量底物的方法
公开(公告)号：US20080110754A1
公开(公告)日：2008-05-15
申请号：US11800273
申请日：2007-05-03
申请人： Shoji Miyazaki , Hiroyuki Tokunaga , Yoshinobu Tokuno , Kazuhiro Matsumoto , Yasuhiko Sawada
发明人： Shoji Miyazaki , Hiroyuki Tokunaga , Yoshinobu Tokuno , Kazuhiro Matsumoto , Yasuhiko Sawada
IPC分类号： G01N27/26
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
摘要翻译：提供了测量样品液体中所含的基板的量的方法。该方法可以减少由生物传感器引起的测量误差。生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源通过连接端子对各个电极施加电压。只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二由驱动电源施加电压引起的连接端子。

68. 发明申请

US20070289350A1 FLAT WIRE MANUFACTURING METHOD OF MANUFACTURING FLAT WIRE FOR RING GEAR 有权
标题翻译：平面线制造扁平线的扁平线制造方法
公开(公告)号：US20070289350A1
公开(公告)日：2007-12-20
申请号：US11755520
申请日：2007-05-30
申请人： Hitoshi Kushida , Osamu Ishigami , Norio Okochi , Shoji Miyazaki
发明人： Hitoshi Kushida , Osamu Ishigami , Norio Okochi , Shoji Miyazaki
IPC分类号： B21C1/00 , B21C37/04 , B21F21/00
CPC分类号： B21C1/00
摘要： A round steel rod having a carbon content between 0.30 and 0.60% is processed by a cold working process to form a flat wire for forming a ring gear. The cold working process forms a semifinished flat wire by at least one cold rolling or cold roller drawing step and at least one two-way or four-way rolling step. The semifinished flat wire is processed by die drawing using a drawing die to obtain a finished flat wire in a last stage of the cold working process. The cold working process reduces the round steel rod at a total area reduction of 65% or below.
摘要翻译：碳含量为0.30〜0.60％的圆钢棒通过冷加工加工，形成用于形成齿圈的扁线。冷加工过程通过至少一个冷轧或冷轧辊拉伸步骤和至少一个双向或四向轧制步骤形成半成品扁线。半成品扁线通过拉丝模具进行模拉加工，在冷加工工序的最后阶段得到成品扁线。冷加工过程减少了总面积减少65％或以下的圆钢棒。

69. 发明授权

US07122111B2 Sample discriminating method 有权
标题翻译：样本识别方法
公开(公告)号：US07122111B2
公开(公告)日：2006-10-17
申请号：US10878536
申请日：2004-06-29
申请人： Hiroyuki Tokunaga , Shoji Miyazaki , Hideyuki Baba , Yoichi Inoue , Kazuo Iketaki , Katsumi Hamamoto
发明人： Hiroyuki Tokunaga , Shoji Miyazaki , Hideyuki Baba , Yoichi Inoue , Kazuo Iketaki , Katsumi Hamamoto
IPC分类号： G01N27/327 , G01N33/48 , G01N31/00
CPC分类号： G01N27/3274 , Y10T436/11
摘要： A glucose sensor system comprising the steps of using as a sample discriminating parameter a ratio (I/ΔI) of a measured current value I to the time-differential value of the current value ΔI, defining a discrimination function that discriminates whether a sample is blood or control fluid and uses the discriminating parameter as an independent variable, quantitating as a discriminating index a numeric value obtained by substituting a discriminating parameter value into this discrimination function, and automatically discriminating, based on this index, whether the sample is blood or a control fluid, whereby a kind of the sample can be automatically quantitated by measuring electric current when a sensor system is used for quantitating the concentration of an analysis object in the sample.
摘要翻译：一种葡萄糖传感器系统，包括以下步骤：将测量电流值I与当前值ΔI的时间微分值的比值（I / DeltaI）用作样本鉴别参数，所述差分值定义了鉴别样品是否为血液的鉴别功能或控制流体，并将鉴别参数用作独立变量，作为鉴别指标，将通过将鉴别参数值代入该鉴别函数而获得的数值，并根据该指标自动鉴别样品是血液还是控制流体，从而当使用传感器系统来定量样品中的分析对象的浓度时，可以通过测量电流来自动量化样品的种类。

70. 发明申请

US20060175206A1 Biosensor, measuring instrument for biosensor, and method of quantifying substrate 有权
公开(公告)号：US20060175206A1
公开(公告)日：2006-08-10
申请号：US11378682
申请日：2006-03-17
申请人： Shoji Miyazaki , Hiroyuki Tokunaga , Yoshinobu Tokuno , Kazuhiro Matsumoto , Yasuhiko Sawada
发明人： Shoji Miyazaki , Hiroyuki Tokunaga , Yoshinobu Tokuno , Kazuhiro Matsumoto , Yasuhiko Sawada
IPC分类号： C12Q1/00 , G01N33/487 , G01F1/64
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式