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    • 67. 发明申请
    • Metabolic Syndrome-Improving Agent and Medicine, Supplement, Functional Food and Food Additive Containing the Same
    • 代谢综合征改善剂和药物,补充剂,功能性食品和食品添加剂含有它
    • US20080132566A1
    • 2008-06-05
    • US11795638
    • 2006-01-20
    • Takao SasakiMasamichi Yano
    • Takao SasakiMasamichi Yano
    • A61K31/352C07D493/02A61P3/00
    • A61K36/752A23L33/105A61K31/37
    • A metabolic syndrome relieving agent that is free from a problem of side effects and can be taken for a long term is provided. Bergamottin is used as an agent for relieving a metabolic syndrome. Since bergamottin has functions of activating PPARα and PPARγ, promoting the secretion of adiponectin in adipocytes and inhibiting the generation of VLDLs in hepatic cells, it is possible to prevent or treat diseases such as insulin resistance, hyperinsulinism, type 2 diabetes, obesity, visceral fat obesity, hypertension, hyperlipemia, arteriosclerosis and the like and thus prevent or treat the metabolic syndrome. Also, as understood from the fact that citrus fruits such as a grapefruit or the like containing bergamottin have been eaten for many years, they have no problems in terms of safety and have a low calorie content, and therefore, they can be taken for a long term. Further, since bergamottin is tasteless and odorless, it does not impair the unique taste of a food when added to this food, so that it can be added to foods and taken.
    • 提供了不存在副作用问题并可长期服用的代谢综合征缓解剂。 使用博加莫汀作为缓解代谢综合征的药物。 由于bergamottin具有激活PPARα和PPARγ的功能,促进脂肪细胞中脂联素的分泌和抑制肝细胞中VLDL的产生,可以预防或治疗诸如胰岛素抵抗,胰岛素抵抗,2型糖尿病,肥胖,内脏脂肪 肥胖症,高血压,高脂血症,动脉硬化等,从而预防或治疗代谢综合征。 另外,由于柑橘类水果例如葡萄柚等含有万古霉素已被吃掉多年,因此在安全性方面没有问题,并且卡路里含量低,因此可以将其用于 长期。 此外,由于香柠檬醇是无味无味的,因此当添加到食物中时,它不会损害食物的独特味道,从而可以将其加入到食物中并服用。
    • 68. 发明申请
    • Metabolic Syndrome-Improving Agent and Medicine, Supplement, Functional Food and Food Additive Containing the Same
    • 代谢综合征改善剂和药物,补充剂,功能性食品和食品添加剂含有它
    • US20080119417A1
    • 2008-05-22
    • US11795774
    • 2006-01-20
    • Takao Sasaki
    • Takao Sasaki
    • A61K31/7048A61K31/353
    • A61K36/752A23L33/105A23V2002/00A61K8/498A61K31/37A61K2800/92A61Q19/00A23V2200/304A23V2200/328A23V2200/326A23V2200/318
    • A metabolic syndrome relieving agent that is free from a problem of side effects and can be taken for a long term is provided. Aurapten is used as an agent for relieving a metabolic syndrome. Since aurapten has functions of activating PPARα and PPARγ, promoting the secretion of adiponectin in adipocytes and inhibiting the generation of VLDLs in hepatic cells, it is possible to prevent or treat diseases such as insulin resistance, hyperinsulinism, type 2 diabetes, obesity, visceral fat obesity, hypertension, hyperlipemia, arteriosclerosis and the like and thus prevent or treat the metabolic syndrome. Also, as understood from the fact that citrus fruits such as a hassaku orange, a sweet summer orange or the like containing aurapten have been eaten for many years, they have no problems in terms of safety and have a low calorie content, and therefore, they can be taken for a long term. Further, since aurapten is tasteless and odorless, it does not impair the unique taste of a food when added to this food, so that it can be added to foods and taken.
    • 提供了不存在副作用问题并可长期服用的代谢综合征缓解剂。 Aurapten用作缓解代谢综合征的药物。 由于aurapten具有激活PPARαα和PPARγ的功能,促进脂肪细胞中脂联素的分泌并抑制肝细胞中VLDL的产生,因此可以预防或治疗诸如胰岛素抵抗,高胰岛素血症, 2型糖尿病,肥胖症,内脏脂肪肥胖症,高血压,高脂血症,动脉硬化等,从而预防或治疗代谢综合征。 另外,由于柑橘类水果如橙子,含有刺槐的甜夏夏等已经吃了多年,因此在安全性方面没有问题,卡路里含量低, 他们可以长期服用。 此外,由于无纺布是无味无味的,因此当添加到食品中时不会损害食品的独特味道,从而可以将其加入到食品中并被摄取。