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61. 发明授权

US5589402A Process for manufacturing a package for mating with a bare semiconductor die 失效
标题翻译：用于制造与裸半导体管芯配合的封装的工艺
公开(公告)号：US5589402A
公开(公告)日：1996-12-31
申请号：US550416
申请日：1995-10-30
申请人： Kenneth C. Ramsey , William J. Miller , William M. Strom
发明人： Kenneth C. Ramsey , William J. Miller , William M. Strom
IPC分类号： H01L23/04 , G02B6/42 , H01L21/00 , H01L21/56 , H01R43/20 , H01L21/60 , H01L21/70
CPC分类号： H01L21/67121 , H01L21/56 , H01R43/20 , H01L2924/0002 , Y10T29/49121
摘要： A method for interconnecting electrical system components. A leadframe (10) having leads (11) is encapsulated within a molding compound to form a first section (36) of the interconnect package (35). The first section (36) optionally includes channels (54). A leadframe (20) having leads (22, 23) is encapsulated within a molding compound to form a second section (37) of the interconnect package (35). The first and second sections (36 and 37, respectively) are coupled together with an adhesive material (43). An end (44) is removed from the interconnect package (35) forming an edge (50). A bare semiconductor chip (51) is coupled to the edge (50).
摘要翻译：一种用于互连电气系统部件的方法。具有引线（11）的引线框架（10）被封装在模制化合物内以形成互连封装（35）的第一部分（36）。第一部分（36）可选地包括通道（54）。具有引线（22,23）的引线框架（20）被封装在模制化合物内以形成互连封装（35）的第二部分（37）。第一和第二部分（36和37分别）用粘合剂材料（43）联接在一起。从形成边缘（50）的互连封装（35）移除端（44）。裸半导体芯片（51）耦合到边缘（50）。

62. 发明授权

US5547812A Composition for eliminating microbridging in chemically amplified photoresists comprising a polymer blend of a poly(hydroxystyrene) and a copolymer made of hydroxystyrene and an acrylic monomer 失效
标题翻译：用于消除化学放大光致抗蚀剂中的微桥接的组合物，其包含聚（羟基苯乙烯）和由羟基苯乙烯制成的共聚物和丙烯酸单体的聚合物共混物
公开(公告)号：US5547812A
公开(公告)日：1996-08-20
申请号：US464229
申请日：1995-06-05
申请人： James P. Collins , Judy Dorn , James T. Fahey , Leo Linehan , William J. Miller , Wayne Moreau , Erik A. Puttlitz , Randolph Smith , Gary Spinillo
发明人： James P. Collins , Judy Dorn , James T. Fahey , Leo Linehan , William J. Miller , Wayne Moreau , Erik A. Puttlitz , Randolph Smith , Gary Spinillo
IPC分类号： G03F7/004 , C08F12/22 , C08F212/00 , C08L25/00 , C08L25/18 , C08L33/04 , G03F7/038 , H01L21/027
CPC分类号： G03F7/038 , Y10S430/11 , Y10S430/111
摘要： Microbridge formation in chemically amplified negative tone photoresists based on poly(hydroxystyrene) (PHS) is avoided when the PHS is blended together with a co-polymer of PHS and an acrylic polymer such as poly(methyl methacrylate) (PMMA). The blend should include at least 10% by weight of the co-polymer. In operation, hydrogen bonding between the hydroxystyrene sub-units and the methacrylate sub-units decreases the availability of sites for crosslinking, and this reduction in crosslinking sites makes the blend less susceptible to formation of polymer resist microbridges. The invention is practicable with a polymers having a wide range of molecular weights (2000-50000 daltons), and development can be achieved using the industry standard 2.38 wt % trimethylammonium hydroxide (TMAH) developer without any adverse impact on the photoresist.
摘要翻译：当PHS与PHS的共聚物和聚（甲基丙烯酸甲酯）（PMMA）等丙烯酸聚合物共混时，避免了基于聚（羟基苯乙烯）（PHS）的化学放大负色调光致抗蚀剂中的微桥形成。共混物应包含至少10重量％的共聚物。在操作中，羟基苯乙烯亚单元和甲基丙烯酸酯亚单位之间的氢键结合降低了用于交联的位点的可用性，并且交联位置的这种减少使得共混物不易形成聚合物抗蚀剂微桥。本发明对于具有广泛分子量（2000-50000道尔顿）的聚合物是可行的，并且可以使用工业标准的2.38重量％的三甲基氢氧化铵（TMAH）显影剂实现显影，而对光致抗蚀剂没有任何不利影响。

63. 发明授权

US5351323A Optical fiber for coupling to elliptically-shaped source 失效
标题翻译：用于耦合到椭圆形源的光纤
公开(公告)号：US5351323A
公开(公告)日：1994-09-27
申请号：US148291
申请日：1993-11-08
申请人： William J. Miller , Robert A. Modavis , Thomas W. Webb
发明人： William J. Miller , Robert A. Modavis , Thomas W. Webb
IPC分类号： G02B6/14 , G02B6/255 , G02B6/28 , G02B6/42 , G02B6/26
CPC分类号： G02B6/4202 , G02B6/14 , G02B6/2551 , G02B6/2835
摘要： An optical system for coupling a laser radiation source to a circularly symmetric single-mode optical fiber. The laser radiation source produces a beam of light having an elliptical mode field. The input end of a coupling fiber, which has a core that is elliptically-shaped in cross-section, is situated in light receiving relationship with respect to the source. The coupling fiber is oriented with respect to the source such that the mode field of the source is aligned with the coupling fiber core to provide the most efficient coupling of light from the source to the fiber. Means such as an evanescent coupler couples light from the output end of the fiber to the circularly symmetric fiber.
摘要翻译：一种用于将激光辐射源耦合到圆形对称单模光纤的光学系统。激光辐射源产生具有椭圆模场的光束。具有椭圆形截面的芯的耦合光纤的输入端相对于光源处于光接收关系。耦合光纤相对于源定向，使得源的模场与耦合光纤芯对准，以提供来自光源的光的最有效的耦合。诸如消逝耦合器的装置将来自光纤的输出端的光耦合到圆形对称光纤。

64. 发明授权

US5091300A Radio-immuno assay for hepatitis B virus PreS2 antibodies 失效
标题翻译：丙型肝炎病毒免疫球蛋白B病毒PRES2抗体
公开(公告)号：US5091300A
公开(公告)日：1992-02-25
申请号：US389207
申请日：1989-08-03
申请人： William M. Hurni , William J. Miller
发明人： William M. Hurni , William J. Miller
IPC分类号： G01N33/569 , G01N33/576 , G01N33/577
CPC分类号： G01N33/5764 , Y10S435/81 , Y10S435/948 , Y10S436/804 , Y10S436/808 , Y10S436/82
摘要： Anti-hepatitis B virus surface protein (anti-HBS) antibody is adsorbed onto the surface of a substratum. Hepatitis B virus PreS2+S (PreS2+S) protein is then adsorbed onto the same surface through the interaction of the anti-HBS antibody with the "S" portion of the PreS2+S protein. The coated surface is then incubated concomitantly with the test sample and a radiolabelled antibody specific for the "PreS2" portion of the PreS2+S protein.

65. 发明授权

US4902323A Method of making fiber optic coupler 失效
标题翻译：制造光纤耦合器的方法
公开(公告)号：US4902323A
公开(公告)日：1990-02-20
申请号：US261693
申请日：1988-10-24
申请人： William J. Miller , Eric H. Urruti
发明人： William J. Miller , Eric H. Urruti
IPC分类号： C03B37/15 , G02B6/28
CPC分类号： G02B6/2835 , C03B37/15
摘要： A fiber optic coupler is formed as follows. Glass optical fibers, each having a core, cladding and coating are disposed within the longitudinal aperture of a capillary tube, the fibers extending beyond each end thereof. The fibers are preferably held taut to effect a tension therein. The coating is removed from that portion of the fibers in the midregion of the tube by oxidation, depolymerization or the like. The coating remains on those portions of the fibers extending into the ends of the apertures to precisely orient the fibers within the tube. The midregion of the tube is heated, collapsed about the fibers, and drawn to reduce the diameter thereof.
摘要翻译：如下形成光纤耦合器。每个具有芯，包层和涂层的玻璃光纤布置在毛细管的纵向孔内，纤维延伸超过其每端。纤维优选保持拉紧以在其中产生张力。通过氧化，解聚等方法从管的中间部分的纤维部分除去涂层。涂层保留在延伸到孔的端部中的纤维的那些部分上，以精确地定向管内的纤维。管的中间区被加热，围绕纤维折叠，并被拉伸以减小其直径。

66. 发明授权

US3997176A Expansible mandrel 失效
标题翻译：可扩展心轴
公开(公告)号：US3997176A
公开(公告)日：1976-12-14
申请号：US614999
申请日：1975-09-19
申请人： James A. Wyckoff , William J. Miller
发明人： James A. Wyckoff , William J. Miller
IPC分类号： B23B31/40
CPC分类号： B23B31/406 , Y10T279/1058
摘要： An expansible mandrel constructed to radially expand equally comprising a generally truncated polyhedron-shaped core member and a plurality of wedge members defining a cylinder, the core member being axially movable relative to the wedge members. Elastic means surrounding the wedge members maintain the wedge members in position relative to the core member.
摘要翻译：可扩展心轴被构造为径向膨胀，包括大体截面的多面体形状的芯构件和限定圆柱体的多个楔形构件，所述芯构件可相对于楔构件轴向移动。围绕楔形构件的弹性装置将楔形构件保持在相对于芯构件的位置。

67. 发明申请

US20100105148A1 MULTI-CHANNEL SWEPT WAVELENGTH OPTICAL INTERROGATION SYSTEM AND METHOD FOR USING SAME 失效
标题翻译：多信道切换波长光学系统及其使用方法
公开(公告)号：US20100105148A1
公开(公告)日：2010-04-29
申请号：US12256852
申请日：2008-10-23
申请人： Stephen J. Caracci , Michael J. Dailey, JR. , William J. Miller , Robert A. Modavis , Deepti J. Mudaliar , David A. Pastel , Michael B. Webb , Qi Wu
发明人： Stephen J. Caracci , Michael J. Dailey, JR. , William J. Miller , Robert A. Modavis , Deepti J. Mudaliar , David A. Pastel , Michael B. Webb , Qi Wu
IPC分类号： G01N21/00 , G01N21/45 , G01N21/41
CPC分类号： G01N21/253 , G01N21/39 , G01N21/45
摘要： A multi-channel swept wavelength optical interrogation system and a method are described herein that enable the interrogation of one or more biosensors which for example could be located within the wells of a microplate. In one embodiment, the optical interrogation system comprises: (a) a tunable laser that emits an optical beam which has a predetermined sequence of distinct wavelengths over a predetermined time period; (b) a distribution unit that splits the optical beam into a plurality of interrogation beams; (c) an array of optical interrogation units that receive and direct the interrogation beams towards an array of biosensors; (d) the array of optical interrogation units receive a plurality of reflected interrogation beams from the array of biosensors; (e) a data processing device that receives and processes information associated with the reflected interrogation beams to determine for example whether or not there was a biochemical interaction on anyone of the biosensors.
摘要翻译：本文描述了多通道扫频波长光询问系统和方法，其能够询问一个或多个生物传感器，例如其可位于微板的孔内。在一个实施例中，光学询问系统包括：（a）可调激光器，其在预定时间段内发射具有预定的不同波长序列的光束; （b）分配单元，其将光束分成多个询问光束; （c）光学询问单元的阵列，其接收并将询问光束定向到生物传感器的阵列; （d）光学询问单元的阵列从生物传感器阵列接收多个反射询问光束; （e）数据处理装置，其接收和处理与所反映的询问光束相关联的信息，以确定例如生物传感器中任何一个生化交互是否存在。

68. 发明申请

US20090202205A1 Adjustable optical tap 有权
公开(公告)号：US20090202205A1
公开(公告)日：2009-08-13
申请号：US12069213
申请日：2008-02-08
申请人： Mark E. Conner , David R. Kozischek , Frances D. Carter , Daniel A. Nolan , William J. Miller , William T. Sawyer
发明人： Mark E. Conner , David R. Kozischek , Frances D. Carter , Daniel A. Nolan , William J. Miller , William T. Sawyer
IPC分类号： G02B6/26
CPC分类号： G02B6/4201 , G02B6/4287 , G02B6/4291
摘要： An adjustable optical tap for adjusting input power, output power and drop power in a communications network includes an enclosure having a plurality of connector assemblies being configured for interconnecting input and output cables; a cover attachable to the enclosure, the cover including a plurality of drop cable ports; and a tunable splitter disposed in the enclosure in communication with the input cable and the drop cable ports, the tunable splitter being configured for adjustment to affect attenuation in a broad wavelength band.

69. 发明授权

US07492998B2 Fiber bundles and methods of making fiber bundles 有权
标题翻译：纤维束和纤维束的制造方法
公开(公告)号：US07492998B2
公开(公告)日：2009-02-17
申请号：US10930294
申请日：2004-08-31
申请人： William J. Miller , M. Heath Rasmussen , Luis A. Zenteno
发明人： William J. Miller , M. Heath Rasmussen , Luis A. Zenteno
IPC分类号： G02B6/04 , G02B6/06
CPC分类号： G02B6/06 , C03C25/1061 , G02B6/04
摘要： The present invention relates to fiber bundles and methods for making fiber bundles. According to one embodiment of the invention, at the endface of the fused fiber bundle, the ratio of the cross-sectional area of the endface to the cross sectional area of the plurality of optical fibers is at least about 2.5. According to another embodiment of the invention, a fused fiber bundle includes a plurality of optical fibers, and a glass tube surrounding the terminal segments of the optical fibers, wherein the refractive index of the glass tube is less than the refractive index of the claddings of the optical fibers. Other embodiments of the present invention provide methods for making fused bundles.
摘要翻译：本发明涉及纤维束和纤维束的制造方法。根据本发明的一个实施例，在熔融纤维束的端面处，端面的横截面积与多根光纤的横截面积之比至少为2.5。根据本发明的另一个实施例，熔融纤维束包括多个光纤，以及围绕光纤的端子段的玻璃管，其中玻璃管的折射率小于玻璃管的折射率光纤。本发明的其它实施方案提供了制备熔融束的方法。

70. 发明申请

US20080003147A1 Fluid handling system for flow-through assay 审中-公开
标题翻译：用于流通测定的流体处理系统
公开(公告)号：US20080003147A1
公开(公告)日：2008-01-03
申请号：US11824420
申请日：2007-06-29
申请人： William J. Miller , Mark L. Morrell , Todd M. Roswech , Po Ki Yuen
发明人： William J. Miller , Mark L. Morrell , Todd M. Roswech , Po Ki Yuen
IPC分类号： B01L3/02
CPC分类号： G01N35/1072 , B01L3/5027 , G01N35/1074
摘要： A fluid handling system for transferring fluids is disclosed. The fluid handling system incorporates a plurality of transfer units for dispensing and/or collecting fluids as part of a closed analytical system. The plurality of transfer units are capable of functioning independently and/or collectively when assembled in a unitary array format. Methods of making and using the fluid handling system are also disclosed. The fluid handling system allows a sub-array of transfer units to shift in a vertical direction independent from a position of another sub-array of transfer units that are assembled within the same fluid head. Therefore, the fluid handling system facilitates multi-port fluid delivery and collection in an array format. Further, the fluid handling system aligned with a sensing surface enables label-free detection assays to be performed in an analytical system.
摘要翻译：公开了一种用于输送流体的流体处理系统。流体处理系统包括用于分配和/或收集流体作为封闭分析系统的一部分的多个转运单元。当以单一阵列格式组装时，多个传送单元能够独立地和/或共同地起作用。还公开了制造和使用流体处理系统的方法。流体处理系统允许传送单元的子阵列在垂直方向上移动，独立于组装在同一流体头内的另一传送单元子阵列的位置。因此，流体处理系统便于以端口流体输送和以阵列格式收集。此外，与感测表面对准的流体处理系统使得能够在分析系统中进行无标记检测分析。

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