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    • 65. 发明授权
    • Cryosurgical fluid supply
    • 冷冻液供应
    • US07641679B2
    • 2010-01-05
    • US11252466
    • 2005-10-17
    • James JoyeRichard S. WilliamsRonald Williams
    • James JoyeRichard S. WilliamsRonald Williams
    • A61F7/12
    • A61B18/0218A61B18/02A61B2017/00292A61B2017/22054A61B2018/0022A61B2018/0212A61B2018/0262
    • Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.
    • 用于将低温冷却流体递送到诸如冷冻手术血管内气囊导管的冷冻手术探针的改进的系统,装置和方法利用在低温流体流动的起始和终止期间的瞬变以缓和由探针接合的组织的治疗温度。 沿着低温流体路径的限流元件间歇性地中断冷却流体的流动,通常循环流体流动和处理温度。 这可以将组织处理温度保持在由稳定流动的低温流体提供的处理温度之上的预定范围内。 在另一方面,室温一次性冷却流体筒填充足够量的冷冻手术液以实现所需的血管内冷冻治疗。
    • 68. 发明授权
    • Cryosurgical fluid supply
    • 冷冻液供应
    • US06786901B2
    • 2004-09-07
    • US10105577
    • 2002-03-21
    • James JoyeRichard S. WilliamsRonald Williams
    • James JoyeRichard S. WilliamsRonald Williams
    • A61B1818
    • A61B18/0218A61B18/02A61B2017/00292A61B2017/22054A61B2018/0022A61B2018/0212A61B2018/0262
    • Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.
    • 用于将低温冷却流体递送到诸如冷冻手术血管内气囊导管的冷冻手术探针的改进的系统,装置和方法利用在低温流体流动的起始和终止期间的瞬变以缓和由探针接合的组织的治疗温度。 沿着低温流体路径的限流元件间歇性地中断冷却流体的流动,通常循环流体流动和处理温度。 这可以将组织处理温度保持在由稳定流动的低温流体提供的处理温度之上的预定范围内。 在另一方面,室温一次性冷却流体筒填充足够量的冷冻手术液以实现所需的血管内冷冻治疗。