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61. 发明授权

US5132112A HS-142-1 compounds 失效
标题翻译： HS-142-1化合物
公开(公告)号：US5132112A
公开(公告)日：1992-07-21
申请号：US682349
申请日：1991-04-09
申请人： Yoshikazu Morishita , Mitsuru Takahashi , Koji Yamada , Tomoyuki Sano , Isao Kawamoto , Katsuhiko Ando , Hiroshi Sano , Yutaka Saito , Hiroshi Kase , Yuzuru Matsuda
发明人： Yoshikazu Morishita , Mitsuru Takahashi , Koji Yamada , Tomoyuki Sano , Isao Kawamoto , Katsuhiko Ando , Hiroshi Sano , Yutaka Saito , Hiroshi Kase , Yuzuru Matsuda
IPC分类号： A61K31/70 , A61K31/7024 , A61P9/02 , A61P13/02 , A61P15/00 , C07H13/06 , C08B37/00 , C12P19/04 , C12R1/645
CPC分类号： C08B37/0024 , C12P19/04
摘要： Compounds comprising a linear .beta.1.fwdarw.6 glucan esterified by caproic acid, the number of D-glucose residues being from 7 to 40 and the number of caproic acid residues being from 2 to 30, may be be obtained by fermentation of a microorganism of the genus Aureobasidium. These compounds are designated HS-142-1. Preferred microorganism is Aureobasidium pullulans var. melanigenum KAC-2383 (FERM-BP 2407).The compounds of the present invention exhibit excellent antagonistic activity to ANP and are capable of inhibiting the bonding of ANP to ANP receptors.

62. 发明授权

US5004833A KS-501 derivatives 失效
标题翻译： KS-501衍生物
公开(公告)号：US5004833A
公开(公告)日：1991-04-02
申请号：US408192
申请日：1989-09-15
申请人： Toru Yasuzawa , Satoshi Nakanishi , Chikara Murakata , Hiroshi Kase , Hiroshi Sano , Koji Yamada
发明人： Toru Yasuzawa , Satoshi Nakanishi , Chikara Murakata , Hiroshi Kase , Hiroshi Sano , Koji Yamada
IPC分类号： C07H15/203
CPC分类号： C07H15/203
摘要： Disclosed are KS-501 derivatives represented by the formula (I) ##STR1## wherein X represents a hydrogen atom or COOR.sub.3, Y represents hydroxy or ##STR2## and R.sub.1, R.sub.2 and R.sub.3 are the same or different and represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, provided that when R.sub.1, R.sub.2 and R.sub.3 are simultaneously hydrogen atoms, and when R.sub.1, R.sub.2 and X are simultaneously hydrogen atoms, Y does not represent ##STR3## and a pharmaceutically acceptable acid addition salt thereof. The KS-501 derivatives have a platelet aggregation-inhibiting property, and are expected to be useful as antithrombotic agent.

63. 发明授权

US4683220A Novel physiologically active substances K-26, a process for preparation thereof and a pharmaceutical composition containing the same 失效
标题翻译：新型生理活性物质K-26，其制备方法和含有它的药物组合物
公开(公告)号：US4683220A
公开(公告)日：1987-07-28
申请号：US912685
申请日：1986-09-26
申请人： Masayuki Yamato , Hiroshi Kase , Isao Kawamoto , Masaji Kasai , Kunikatsu Shirahata , Takashi Deguchi , Katsuichi Shuto , Akira Karasawa , Ryo Okachi , Kiyoshi Nakayama
发明人： Masayuki Yamato , Hiroshi Kase , Isao Kawamoto , Masaji Kasai , Kunikatsu Shirahata , Takashi Deguchi , Katsuichi Shuto , Akira Karasawa , Ryo Okachi , Kiyoshi Nakayama
IPC分类号： C12P21/00 , A61K35/74 , A61K38/00 , A61P9/12 , C07F9/38 , C07F9/40 , C07K5/06 , C07K14/005 , C07K14/195 , C07K14/41 , C12P21/02 , C12R1/01 , A61K37/64
CPC分类号： C07F9/3808 , C07F9/3882 , C07F9/4006 , C07F9/4056 , C07K5/06191 , A61K38/00
摘要： Disclosed is a novel physiologically active substance, K-26, a process for preparation thereof and a pharmaceutical composition containing the same. The composition of matter, K-26, is useful as a hypotensive agent.
摘要翻译：公开了一种新的生理活性物质K-26，其制备方法和含有该生物活性物质的药物组合物。物质的组成，K-26，作为一种降压剂是有用的。

64. 发明授权

US4564995A Composite machine tool 失效
标题翻译：复合机床
公开(公告)号：US4564995A
公开(公告)日：1986-01-21
申请号：US714055
申请日：1985-03-20
申请人： Hiroshi Kase
发明人： Hiroshi Kase
IPC分类号： B23Q7/00 , B23Q1/01 , B23Q7/14 , B23Q39/00 , B23Q39/02
CPC分类号： B23Q39/00 , B23Q1/012 , B23Q7/1431 , B23Q7/1489 , Y10T29/5107 , Y10T29/5124 , Y10T29/5136 , Y10T29/52 , Y10T409/308288 , Y10T82/2511
摘要： A composite machine tool for metal working, provided with a pair of vertical columns. On the front and rear sides of the vertical columns, there are provided a vertical lathe and a milling machine, respectively, able to be driven and operated independently of each other. Machining by these machine tools is effected on a workpiece rested on a pallet. A pallet transfer apparatus for conveying a succession of pallets with workpieces is provided between the vertical lathe and the milling machine and between the vertical columns. When each turning operation in the vertical lathe is finished, the corresponding pallet with the workpiece rested thereon is immediately conveyed into the milling machine by the pallet transfer apparatus. The composite machine tool is particularly useful in reducing the time for conveying comparatively heavy workpieces.
摘要翻译：一种用于金属加工的复合机床，具有一对垂直柱。在垂直立柱的前侧和后侧，分别设置有能够彼此独立地驱动和操作的立式车床和铣床。通过这些机床的加工在搁置在托盘上的工件上进行。在垂直车床和铣床之间以及垂直立柱之间提供用于在工件上传送一系列托盘的托盘传送装置。当垂直车床中的每个车削操作完成时，其上搁置工件的相应托盘立即通过托盘传送装置传送到铣床中。复合机床特别适用于减少输送较重工件的时间。

65. 发明授权

US4522812A Novel physiologically active substance K-4, a process for preparation thereof and a pharmaceutical composition containing the same 失效
标题翻译：新型生理活性物质K-4，其制备方法和含有它的药物组合物
公开(公告)号：US4522812A
公开(公告)日：1985-06-11
申请号：US407082
申请日：1982-08-11
申请人： Toshiro Koguchi , Hiroshi Kase , Isao Kawamoto , Masaji Kasai , Kunikatsu Shirahata , Ryo Okachi , Kiyoshi Nakayama
发明人： Toshiro Koguchi , Hiroshi Kase , Isao Kawamoto , Masaji Kasai , Kunikatsu Shirahata , Ryo Okachi , Kiyoshi Nakayama
IPC分类号： C12N1/20 , A61K35/74 , A61K38/00 , A61P9/12 , C07F9/38 , C07F9/40 , C07G99/00 , C12P1/06 , C12R1/03 , C07C103/52 , A61K37/02
CPC分类号： C07F9/4056 , C07F9/3808 , C07F9/3882 , C07F9/4006 , A61K38/00
摘要： Disclosed is a novel physiologically active substance K-4 which has a hypotensive activity, a process production thereof and a pharmaceutical composition containing the same.
摘要翻译：公开了一种具有低血压活性的新型生理活性物质K-4，其制备方法和含有它们的药物组合物。

66. 发明授权

US08661511B2 Apparatus registration method and server device 有权
标题翻译：设备注册方法和服务器设备
公开(公告)号：US08661511B2
公开(公告)日：2014-02-25
申请号：US13388127
申请日：2010-10-26
申请人： Hiroshi Kase
发明人： Hiroshi Kase
IPC分类号： H04L29/06
CPC分类号： H04N5/765 , H04N21/6334
摘要： A method registers access permission from a first device to a second device over a network. When receiving via the network a connection request from the first device of which access permission is not registered, the second device rejects connection from the first device, and shifts to the first mode. In a first mode, the second device detects user's operation on the second device, and judges whether the detected user's operation is an operation regarding viewing of a reproduction signal from the second device. If the user's operation is not the operation regarding viewing, the second device shifts to the second mode for registering access permission. If the user's operation is the operation regarding viewing, the second device does not shift to the second mode.
摘要翻译：一种方法通过网络注册从第一设备到第二设备的访问权限。当经由网络接收到来自未登记访问许可的第一设备的连接请求时，第二设备拒绝来自第一设备的连接，并转移到第一模式。在第一模式中，第二设备检测用户对第二设备的操作，并且判断检测到的用户的操作是否是关于从第二设备观看再现信号的操作。如果用户的操作不是关于观看的操作，则第二设备转移到用于注册访问许可的第二模式。如果用户的操作是关于观看的操作，则第二设备不转移到第二模式。

67. 发明授权

US08440678B2 Pharmaceutical composition 有权
标题翻译：药物组成
公开(公告)号：US08440678B2
公开(公告)日：2013-05-14
申请号：US13234355
申请日：2011-09-16
申请人： Hiroshi Kase , Minoru Kobayashi , Shizuo Shiozaki , Akihisa Mori , Naoki Seno
发明人： Hiroshi Kase , Minoru Kobayashi , Shizuo Shiozaki , Akihisa Mori , Naoki Seno
IPC分类号： A01N43/90 , A01N33/02 , A61K31/522 , A61K31/13 , C07D473/00 , C07D403/02 , C07C211/00
CPC分类号： A61K31/522 , A61K31/137 , A61K31/138 , A61K31/16 , A61K31/335 , A61K31/343 , A61K31/36 , A61K31/38 , A61K31/381 , A61K31/435 , A61K31/4525 , A61K31/496 , A61K31/52 , A61K31/5375 , A61K31/55 , A61K31/553 , A61K45/06 , A61K2300/00
摘要： The present invention provides pharmaceutical compositions, which are useful for treatment of depression and the like, and which comprises a compound having an adenosine A2A receptor antagonistic activity such as (E)-8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione or a pharmaceutically acceptable salt thereof and an antidepressant drug (for example, a tricyclic antidepressant, a tetracyclic antidepressant, a selective serotonin reuptake inhibitor, a selective noradrenalin reuptake inhibitor, a dopamine reuptake inhibitor, a serotonin-noradrenalin reuptake inhibitor, monoamine oxidase inhibitor, a 5-HT2 antagonist or the like), and the like.
摘要翻译：本发明提供了可用于治疗抑郁症等的药物组合物，其包含具有腺苷A 2A受体拮抗活性的化合物，例如（E）-8-（3,4-二甲氧基苯乙烯基）二乙基-7-甲基-3,7-二氢-1H-嘌呤-2,6-二酮或其药学上可接受的盐和抗抑郁药（例如，三环抗抑郁药，四环抗抑郁药，选择性5-羟色胺再摄取抑制剂，选择性去甲肾上腺素再摄取抑制剂，多巴胺再摄取抑制剂，5-羟色胺去甲肾上腺素再摄取抑制剂，单胺氧化酶抑制剂，5-HT2拮抗剂等）等。

68. 发明授权

US08072548B2 Output control apparatus controlling an output of video or audio by automatically switching an input of a reproduction device and an output control system, a reproduction apparatus and a television for performing the same 有权
标题翻译：输出控制装置通过自动切换再现装置和输出控制系统的输入来控制视频或音频的输出，再现装置和用于执行其的电视
公开(公告)号：US08072548B2
公开(公告)日：2011-12-06
申请号：US11661500
申请日：2006-07-11
申请人： Junji Yoshida , Masazumi Yamada , Hiroshi Kase
发明人： Junji Yoshida , Masazumi Yamada , Hiroshi Kase
IPC分类号： H04N5/268 , H04N5/783 , H04N5/775
CPC分类号： H04N5/775 , H04N5/781 , H04N5/85 , H04N9/8042
摘要： An output control apparatus capable of appropriately switching screens depending on a current situation, and a reproduction apparatus and a television performing the same. The television includes a tuner receiving a television broadcast, a data input I/F receiving video or audio from a DVD recorder, and a command input I/F receiving a command from the DVD recorder. Further, the television includes a user input unit receiving an instruction from a user, a switch selecting the tuner or the data input I/F, an output processing unit controlling an output of video or audio from the switch, and a control unit (i) switching the switch to the tuner when the switch selects the data input I/F when a first command is inputted from the command input I/F and (ii) not switching the switch when the switch does not select the data input I/F.
摘要翻译：一种能够根据当前情况适当地切换屏幕的输出控制装置，以及执行该屏幕的再现装置和电视机。电视机包括接收电视广播的调谐器，来自DVD记录器的数据输入I / F接收视频或音频，以及从DVD记录器接收命令的命令输入I / F。此外，电视机包括接收来自用户的指令的用户输入单元，选择调谐器的开关或数据输入I / F，控制来自开关的视频或音频的输出的输出处理单元，以及控制单元）当从命令输入I / F输入第一命令时，当开关选择数据输入I / F时切换开关到调谐器，以及（ii）当开关没有选择数据输入I / F时切换开关。

69. 发明授权

US07759355B2 Adenosine A2A receptor antagonists for treating restless legs syndrome or nocturnal myoclonus 有权
标题翻译：用于治疗不宁腿综合征或夜间肌阵挛的腺苷A2A受体拮抗剂
公开(公告)号：US07759355B2
公开(公告)日：2010-07-20
申请号：US10523603
申请日：2003-08-27
申请人： Hiroshi Kase , Naoki Seno , Akihisa Mori , Dayao Zhao
发明人： Hiroshi Kase , Naoki Seno , Akihisa Mori , Dayao Zhao
IPC分类号： A61K31/522 , A61P25/00 , A61P25/14
CPC分类号： A61K31/00 , A61K31/522
摘要： The present invention provides methods of treating restless legs syndrome or related disorders, comprising administering an effective amount of at least one adenosine A2A receptor antagonist to a patient in need thereof. More preferably the adenosine A2A receptor antagonist is a xanthine derivative or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供了治疗不宁腿症状或相关病症的方法，包括向有需要的患者施用有效量的至少一种腺苷A 2A受体拮抗剂。更优选地，腺苷A 2A受体拮抗剂是黄嘌呤衍生物或其药学上可接受的盐。

70. 发明申请

US20090051825A1 VIDEO/AUDIO OUTPUT DEVICE AND EXTERNAL SPEAKER CONTROL APPARATUS 有权
标题翻译：视频/音频输出设备和外部扬声器控制设备
公开(公告)号：US20090051825A1
公开(公告)日：2009-02-26
申请号：US11911697
申请日：2006-09-21
申请人： Sako Asayama , Hiroshi Kase , Mitsuteru Kataoka
发明人： Sako Asayama , Hiroshi Kase , Mitsuteru Kataoka
IPC分类号： H04N5/60
CPC分类号： H04R3/12 , H04N5/60 , H04N5/63 , H04N21/436 , H04N21/4396 , H04N21/44227 , H04N21/44231 , H04R27/00 , H04R2499/15
摘要： The invention provides an external speaker control apparatus for causing only one of an internal speaker and an external speaker to output audio when a power supply of the external speaker control apparatus which controls the external speaker changes from an off state to an on state, the external speaker being a speaker outside a video and audio output apparatus. The external speaker control apparatus includes a microcomputer for detecting the change of the power supply of an amplifier from an off state to an on state and a HDMI/CEC communication unit for outputting an instruction requesting output of information which indicates the audio output mode to the video and audio output apparatus while at the same time receiving the information indicating the audio output mode from the video and audio output apparatus in the case where the microcomputer detects the change of the power supply from an off state to an on state, wherein the microcomputer controls the output of the audio from the external speaker based on the information indicating the audio output mode.
摘要翻译：本发明提供了一种外部扬声器控制装置，用于当控制外部扬声器的外部扬声器控制装置的电源从断开状态变为接通状态时，仅使一个内部扬声器和外部扬声器中的一个输出音频，外部扬声器是视频和音频输出设备外的扬声器。外部扬声器控制装置包括：微型计算机，用于检测放大器从关闭状态到接通状态的电源的变化;以及HDMI / CEC通信单元，用于将指示音频输出模式的信息的输出的指令输出到视频和音频输出装置，同时在微型计算机检测到电源从关闭状态变为打开状态的情况下同时从视频和音频输出装置接收指示音频输出模式的信息，其中微型计算机基于指示音频输出模式的信息来控制来自外部扬声器的音频的输出。

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