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61. 发明授权

US5541353A Keyboard instrument for selectively producing mechanical sounds and synthetic sounds without any mechanical vibrations on music wires 失效
标题翻译：用于选择性地产生机械声音和合成声音的键盘乐器，而不会在音乐线上产生任何机械振动
公开(公告)号：US5541353A
公开(公告)日：1996-07-30
申请号：US324685
申请日：1994-10-18
申请人： Kiyoshi Kawamura , Shinya Koseki , Nobuo Sugiyama , Masahiro Wada
发明人： Kiyoshi Kawamura , Shinya Koseki , Nobuo Sugiyama , Masahiro Wada
IPC分类号： G10C5/00 , G10H1/34 , G10D15/00
CPC分类号： G10H1/0066 , G10C5/005 , G10H1/344 , G10H1/346 , G10H2230/011 , G10H2240/056
摘要： In order to give piano-like key touch to a player in an electronically sound producing mode, a keyboard incorporated in a musical instrument is linked with key action mechanisms associated with hammer mechanisms, and a stopper blocks the hammer shanks before the hammers strike the strings so that noises are not mixed with synthesized tones.
摘要翻译：为了以电子声音产生模式给玩家提供类似钢琴般的按键触摸，结合在乐器中的键盘与与锤击机构相关联的键动作机构连接，并且止动器在琴锤击弦之前阻挡锤柄使得噪声不与合成色调混合。

62. 发明授权

US5451708A Automatic player piano equipped with monitoring system on key action for improving fidelity of reproduced music 失效
标题翻译：自动播放器钢琴配备监控系统，提高重现音乐保真度的关键动作
公开(公告)号：US5451708A
公开(公告)日：1995-09-19
申请号：US57619
申请日：1993-05-05
申请人： Yuji Fujiwara , Kiyoshi Kawamura , Tsutomu Sasaki
发明人： Yuji Fujiwara , Kiyoshi Kawamura , Tsutomu Sasaki
IPC分类号： G10C3/16 , G10F1/02 , G11B31/02
CPC分类号： G10F1/02
摘要： A controller module associated with a mechanical piano memorizes a plurality sets of parameters produced from detected trajectories of depressed keys in a floppy disk in a recording mode of operation, and restores the trajectories on the basis of the sets of parameters for driving an actuator array associated with a keyboard in a playback mode, thereby exactly reproducing a music without sacrifice of the memory capacity.
摘要翻译：与机械钢琴相关联的控制器模块在记录操作模式中存储从软盘中的按压键的检测轨迹产生的多组参数，并且基于用于驱动相关联的致动器阵列的参数集来恢复轨迹使用键盘处于回放模式，从而在不牺牲存储器容量的情况下精确地再现音乐。

63. 发明授权

US5434349A Keyboard instrument selectively entering into an acoustic mode and a silent mode through a sliding motion of a stopper 失效
标题翻译：键盘乐器通过止动器的滑动运动选择性进入声学模式和静音模式
公开(公告)号：US5434349A
公开(公告)日：1995-07-18
申请号：US215295
申请日：1994-03-21
申请人： Kiyoshi Kawamura
发明人： Kiyoshi Kawamura
IPC分类号： G10C5/00 , G10D15/00 , G10H1/34
CPC分类号： G10C5/005
摘要： A keyboard instrument selectively enters into an acoustic sound mode for producing piano tones and into an electronic sound mode for producing synthetic tones, and comprises an acoustic piano, an electronic sound generating system and a mode controlling system, wherein the mode controlling system has a stopper slidable along strings of the acoustic piano so that the strings are struck by or blocked from hammers of the acoustic depending upon the position of the stopper.
摘要翻译：键盘乐器选择性地进入用于产生钢琴音调的声音模式和用于产生合成音调的电子声音模式，并且包括原声钢琴，电子声音产生系统和模式控制系统，其中模式控制系统具有止动器可以沿着原声钢琴的弦线滑动，这样根据挡块的位置，琴弦被声音敲击或阻挡。

64. 发明授权

US5386083A Keyboard instrument having hammer stopper outwardly extending from hammer shank and method of remodeling piano into the keyboard instrument 失效
标题翻译：具有从锤柄向外延伸的锤塞的键盘乐器和将钢琴重新配置到键盘乐器中的方法
公开(公告)号：US5386083A
公开(公告)日：1995-01-31
申请号：US160606
申请日：1993-11-30
申请人： Kiyoshi Kawamura
发明人： Kiyoshi Kawamura
IPC分类号： G10C5/00 , G10H1/34 , G10C3/12 , G10D15/00
CPC分类号： G10H1/346 , G10C5/005 , Y10S84/07
摘要： A hammer stopper is moved into and outof an orbit of an extension of a hammer shank depending upon an operation mode, and the extension rebounds on the hammer stopper in an electronic sound producing mode between an escape of a jack from a butt and a strike of a hammer head at a set of strings so that a player performs a music through synthesized sounds without sacrifice of the piano key-touch.
摘要翻译：根据操作模式，锤式止动器被移入和移动锤柄的延伸部的轨道，并且延伸部在电子声音产生模式下在电子声音产生模式下在插座从屁股的逸出和罢工之间弹回以一组琴弦的锤头，使得玩家通过合成的声音执行音乐而不牺牲钢琴按键触摸。

65. 发明授权

US5359097A Process for preparation of glycidyl ether 失效
标题翻译：缩水甘油醚的制备方法
公开(公告)号：US5359097A
公开(公告)日：1994-10-25
申请号：US571543
申请日：1990-08-22
申请人： Kiyoshi Kawamura , Tomio Ota
发明人： Kiyoshi Kawamura , Tomio Ota
IPC分类号： C07D301/28 , C07D303/22 , C07D405/12 , C07D407/12 , C07D417/12 , C07D311/04
CPC分类号： C07D303/22 , C07D407/12
摘要： A process is provided for preparation of a glycidyl ether represented by the general formula ##STR1## wherein A represents an aryl group optionally having a substituent or a heteroaryl group optionally having a substituent, and the carbon atom marked with * is an asymmetric carbon,which comprises reacting an aryl alcohol represented by the general formulaA--OH (I)wherein A is as defined above,with an epihalohydrin in the presence of a quaternary ammonium salt; and, if necessary, further treating the reaction product with a base. According to the present process, it is possible to prepare by simple procedures and in a high optical purity glycidyl ethers of the above formula (II) useful as an intermediate for preparation of medicines, particularly medicines having .beta.-adrenoreceptor blocking action or the like.
摘要翻译： PCT No.PCT / JP89 / 01293 Sec。 371 1990年7月18日第 102（e）日期1990年7月18日PCT提交1989年12月25日PCT公布。出版物WO90 / 07506 日本1990年7月12日提供了一种制备由任选具有取代基的通式或由任选具有取代基的杂芳基表示的缩水甘油醚的方法，标有*的碳原子是不对称碳，其包括使由季铵盐存在下的表卤代醇，由通式A-OH（I）表示的芳基醇，其中A如上所定义; 并且如果需要，用碱进一步处理反应产物。根据本方法，可以通过简单的方法和上述式（II）的高光学纯度的缩水甘油醚制备，其可用作制备药物的中间体，特别是具有β-肾上腺素受体阻断作用的药物等。

66. 发明授权

US5256619A Heat-sensitive recording material 失效
标题翻译：热敏记录材料
公开(公告)号：US5256619A
公开(公告)日：1993-10-26
申请号：US725527
申请日：1991-07-03
申请人： Masatoshi Yoshida , Katsuyuki Kono , Kiyoshi Kawamura
发明人： Masatoshi Yoshida , Katsuyuki Kono , Kiyoshi Kawamura
IPC分类号： B41M5/28 , B41M5/30 , B41M5/337 , B41M5/40 , B41M5/42 , B41M5/44
CPC分类号： B41M5/44 , B41M5/443
摘要： A heat-sensitive recording material excelled in surface gloss and printing concentration is disclosed.The disclosed heat-sensitive recording material with a heat-sensitive color-developing layer formed on a supporting member features provision on the surface of the heat-sensitive color-developing layer of a protective coating containing crosslinked microfine particles (B) having substantially no glass transition temperature, 0.5 .mu.m or less in mean particle size and 0.05 or less in the difference in refractive index from the solid content of aqueous resin despersion which are obtainable by emulsion-polymerizing vinyl-containing monomers containing 15 weight % or more of polymeric multifunctional monomers together with the aqueous resin dispersion (A).

67. 发明授权

US5244288A Method and apparatus for braille display of information from CRT screen 失效
标题翻译：从CRT屏幕显示信息的方法和装置
公开(公告)号：US5244288A
公开(公告)日：1993-09-14
申请号：US901076
申请日：1992-06-19
申请人： Hideji Nagaoka , Shunsuke Yamagata , Joji Ando , Kiyoshi Kawamura , Koichi Urakami , Satoru Kondo
发明人： Hideji Nagaoka , Shunsuke Yamagata , Joji Ando , Kiyoshi Kawamura , Koichi Urakami , Satoru Kondo
IPC分类号： B41J2/00 , B41J3/32 , B41J5/30 , G06F3/12 , G09B21/00
CPC分类号： G09B21/003
摘要： A method and apparatus whereby information appearing on a CRT screen (410) is separately displayed in braille, using a braille web (100) in a loop form and made partly or wholly from a shape memory resin. The information from a CRT screen (410) is input to the web (100) by a braille printer (300) at a temperature within a range below the glass transition temperature of the resin. After the information has been read by the user, the displayed web portion is heated above the glass transition temperature by a heating roller (200) so that the web recovers its original, non-braille shape. The web is conveyed by a driving roller (210) along with the heating roller (200) and a driven roller (220) in the directions indicated by arrows in FIG. 1 for repeated use.

68. 发明授权

US4994520A Carbon black-graft polymer, method for production thereof, and use thereof 失效
标题翻译：炭黑接枝聚合物，其制备方法及其用途
公开(公告)号：US4994520A
公开(公告)日：1991-02-19
申请号：US533780
申请日：1990-06-06
申请人： Yoshikuni Mori , Mitsuo Kushino , Hayato Ideda , Nobuaki Urashima , Masuji Izubayashi , Shigeru Tanimori , Yoshihiro Arita , Kiyoshi Kawamura , Kenji Minami , Yoshinori Sano
发明人： Yoshikuni Mori , Mitsuo Kushino , Hayato Ideda , Nobuaki Urashima , Masuji Izubayashi , Shigeru Tanimori , Yoshihiro Arita , Kiyoshi Kawamura , Kenji Minami , Yoshinori Sano
IPC分类号： B41M5/395 , C08F292/00 , C08G83/00 , C08K3/18 , G03G9/09 , G11B5/73
CPC分类号： B41M5/395 , C08F292/00 , C08G83/001 , G03G9/0904 , G11B5/7305
摘要： A carbon black-graft polymer, produced by causing a polymer possessing within the molecular unit thereof at least one reactive group selected from the class consisting of aziridine group, oxazoline group. N-hydroxyalkylamide group, epoxy group, and thioepoxy group to react with carbon black. The polymer can be used as a toner for electrostatically charged image, resin composition, coating composition, ink for thermographic transfer, coating agent for magnetic recording medium, rubber composition, and carbon black dispersion and the like.

69. 发明授权

US4216225A Methylmethioninesulfonium compounds, process for their preparation, and pharmaceutical compositions containing them 失效
标题翻译：甲基亚氨基锍化合物，其制备方法和含有它们的药物组合物
公开(公告)号：US4216225A
公开(公告)日：1980-08-05
申请号：US906567
申请日：1978-05-16
申请人： Masami Shiratsuchi , Kiyoshi Kawamura , Hisashi Kunieda , Naoki Machida , Toshihiro Akashi , Masahiko Nagakura
发明人： Masami Shiratsuchi , Kiyoshi Kawamura , Hisashi Kunieda , Naoki Machida , Toshihiro Akashi , Masahiko Nagakura
IPC分类号： A61K31/195 , A61K31/16 , A61K31/22 , A61P1/04 , C07C67/00 , C07C325/00 , C07C381/12 , C07D213/82 , A61K31/55 , A61K31/215
CPC分类号： C07D213/82
摘要： Methylmethioninesulfonium compounds of the formula ##STR1## wherein X.crclbar. represents an anion;R.sup.1 represents a hydrogen atom or an acyl group of the formula -COR.sup.3 in which R.sup.3 represents an alkyl group with 1 to 20 carbon atoms, the group --CH.sub.2).sub.2 COOH or the group ##STR2## in which Z represents a direct bond or a methylene or vinylene linkage, Y represents C or N, R.sup.4 represents a member selected from the class consisting of a hydrogen atom, lower alkyl groups, lower alkoxy groups, di-lower-alkylamino groups and a sulfamoyl group, n is a number of 1 to 3, and two or more R.sup.4 groups may be identical or different; andR.sup.2 represents the group --COOR.sup.5 in which R.sup.5 represents a hydrogen atom, an alkyl group with 1 to 5 carbon atoms or a metal- or metal complex-forming moiety, or the group ##STR3## in which R.sup.6 groups may be identical or different, and each represent a hydrogen atom or an alkyl group with 1 to 5 carbon atoms, with the proviso that when R.sup.1 represents a hydrogen atom, R.sup.2 is not --COOH; when R.sup.1 represents a hydrogen atom and R.sup.2 represents --CONH.sub.2, X.crclbar. is not Cl.crclbar.; and when R.sup.1 is --COCH.sub.3 and R.sup.2 is --COOCH.sub.3, X.crclbar. is not I.crclbar..The compounds can be easily prepared from methionine as a starting material by a combination of known unit reactions such as methylsulfonium-forming reaction, acylation, amidation, esterification and metal salt-forming reaction. These compounds are especially useful for treating ulcers.
摘要翻译：其中X（ - ）表示阴离子的式“IMAGE”的甲基甲硫氨onium化合物; R 1表示氢原子或式-COR 3的酰基，其中R 3表示具有1至20个碳原子的烷基，基团-CH 2）2 COOH或其中Z表示直接键或基团亚甲基或亚乙烯基，Y表示C或N，R4表示选自氢原子，低级烷基，低级烷氧基，二低级烷基氨基和氨磺酰基的成员，n为1 至3个，并且两个或更多个R 4基团可以相同或不同; 并且R 2表示其中R 5表示氢原子，具有1至5个碳原子的烷基或金属或金属络合物形成部分的基团-COOR 5或其中R6基团可以相同或不同的基团并且各自表示氢原子或具有1至5个碳原子的烷基，条件是当R 1表示氢原子时，R 2不是-COOH; 当R 1表示氢原子且R 2表示-CONH 2时，X（ - ）不是Cl（ - ）; 当R1是-COCH3且R2是-COOCH3时，X（ - ）不是I（ - ）。通过已知的单元反应如甲基锍形成反应，酰化，酰胺化，酯化和金属盐形成反应的组合，可以容易地从甲硫氨酸作为原料制备化合物。这些化合物特别适用于治疗溃疡。

70. 发明授权

US08829026B2 Sulfamoyl benzoic acid heterobicyclic derivatives as TRPM8 antagonists 有权
标题翻译：磺酰氨基苯甲酸异双环衍生物作为TRPM8拮抗剂
公开(公告)号：US08829026B2
公开(公告)日：2014-09-09
申请号：US13820598
申请日：2011-10-03
申请人： Kiyoshi Kawamura , Yuji Shishido , Masashi Ohmi
发明人： Kiyoshi Kawamura , Yuji Shishido , Masashi Ohmi
IPC分类号： A61K31/44 , C07D405/00
CPC分类号： C07D471/04 , A61K31/443 , A61K31/4439 , A61K31/444 , A61K31/4709 , A61K45/06 , C07D209/08 , C07D215/12 , C07D231/56 , C07D249/18 , C07D307/79 , C07D401/12 , C07D405/04 , C07D405/12 , C07D405/14
摘要： The present invention relates to sulfamoyl benzoic acid heterobicyclic derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPMb8 receptor.
摘要翻译：本发明涉及式（I）的氨磺酰基苯甲酸异双环衍生物或其药学上可接受的盐或其前药，其制备方法，含有它们的药物组合物及其在治疗各种疾病中的用途， TRPMb8受体。

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