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61. 发明授权

US08892061B2 Methods, devices, and computer program products for tracking receipt and determining effectiveness of radio broadcast signals 有权
标题翻译：用于跟踪无线电广播信号的收据和确定有效性的方法，设备和计算机程序产品
公开(公告)号：US08892061B2
公开(公告)日：2014-11-18
申请号：US13070538
申请日：2011-03-24
申请人： James Gordon Beattie, Jr. , Stephen J. Griesmer , Shiv Kumar
发明人： James Gordon Beattie, Jr. , Stephen J. Griesmer , Shiv Kumar
IPC分类号： H03C1/62 , H04W24/08
CPC分类号： H04W24/08
摘要： Receipt of a radio broadcast signal by a mobile communication device is tracked based on a signal strength measurement signal and location information. The signal strength measurement signal indicate a signal strength of the radio broadcast signal, received via a communication channel and measured at the mobile communication device, over a particular time period. The location information indicates a location of the mobile communication device within a geographic area over the particular time period. Effectiveness of the radio broadcast signal is determined with respect to receipt of the radio broadcast signal by a plurality of mobile communication devices within the geographic area over the particular time period.
摘要翻译：基于信号强度测量信号和位置信息跟踪由移动通信设备接收的无线电广播信号。信号强度测量信号指示在特定时间段内通过通信信道接收并在移动通信设备测量的无线电广播信号的信号强度。位置信息指示在特定时间段内的地理区域内的移动通信设备的位置。无线电广播信号的有效性是针对特定时间段内的地理区域内的多个移动通信设备接收无线电广播信号而确定的。

62. 发明申请

US20120151549A1 User Assistance Via Customer Premises Equipment Media Files 失效
标题翻译：用户协助通过客户驻地设备媒体文件
公开(公告)号：US20120151549A1
公开(公告)日：2012-06-14
申请号：US12964540
申请日：2010-12-09
申请人： Shiv Kumar , Paritosh Bajpay , John Michael Donovan , Narendra Ravi
发明人： Shiv Kumar , Paritosh Bajpay , John Michael Donovan , Narendra Ravi
IPC分类号： H04N7/173
CPC分类号： H04N21/6547 , H04N17/004 , H04N17/04 , H04N21/23614 , H04N21/478 , H04N21/6582
摘要： A particular customer premises equipment (CPE) device includes a display interface, a processor, and a memory accessible to the processor. The memory includes a plurality of media files that include user assistance information. The memory also includes instructions executable by the processor to access a media file of the plurality of media files and, in response to a user request for assistance, send content of the media file to a display device via a display interface.
摘要翻译：特定的客户驻地设备（CPE）设备包括显示接口，处理器和处理器可访问的存储器。存储器包括包括用户辅助信息的多个媒体文件。存储器还包括可由处理器执行以访问多个媒体文件的媒体文件的指令，并且响应于用户的帮助请求，经由显示接口将媒体文件的内容发送到显示设备。

63. 发明申请

US20120052857A1 SYSTEM AND METHOD FOR REPORTING LOSS OF BROADBAND CONNECTIVITY 有权
标题翻译：报告宽带连接损失的系统和方法
公开(公告)号：US20120052857A1
公开(公告)日：2012-03-01
申请号：US12868206
申请日：2010-08-25
申请人： Shiv Kumar , Paritosh Bajpay , Jackson Liu , Narendra Ravi
发明人： Shiv Kumar , Paritosh Bajpay , Jackson Liu , Narendra Ravi
IPC分类号： H04W24/00 , H04W4/12
CPC分类号： H04W24/08 , H04L12/2898 , H04W24/10 , H04W84/045
摘要： The subject disclosure provides a system and methods for a central network monitoring authority to be automatically alerted upon loss of broadband connectivity at a residential gateway. In connection with detecting a connectivity loss in a residential gateway, traceable alert data is created, a mobile device is located within range of an associated femto cell, the traceable alert data is provided to the mobile device; and the mobile device is then employed to transmit the traceable alert data to a central network monitoring authority.
摘要翻译：主题公开提供了一种用于中央网络监视机构在家庭网关的宽带连接丢失时自动警报的系统和方法。结合检测住宅网关中的连通性损失，创建可跟踪的警报数据，移动设备位于相关联的毫微微小区的范围内，可追踪警报数据被提供给移动设备; 然后使用移动设备将可跟踪的警报数据发送到中央网络监视机构。

64. 发明授权

US07827987B2 Ball joint for providing flexibility to a gas delivery pathway 有权
标题翻译：用于为气体输送路径提供灵活性的球形接头
公开(公告)号：US07827987B2
公开(公告)日：2010-11-09
申请号：US11155807
申请日：2005-06-17
申请人： Brian Woodard , Ngee Lee , Edward M. Geiselhart , Chris Houghton , Benjamin K. Sun , Shiv Kumar
发明人： Brian Woodard , Ngee Lee , Edward M. Geiselhart , Chris Houghton , Benjamin K. Sun , Shiv Kumar
IPC分类号： A61M16/08 , A61M16/00
CPC分类号： A61M16/08 , A61M16/06 , A61M16/0633 , A61M16/0655 , A61M16/0683 , A61M16/0825 , Y10S128/912 , Y10T403/31 , Y10T403/315 , Y10T403/32729
摘要： A system for adjusting a gas delivery mask is provided. The system may include a first housing portion, a first rim flexibly coupled to the first housing portion by a flexible member, a second housing portion coupled to the first housing portion, a second rim associated with the second housing portion, and a ball rotatably disposed between the first and second rims and having a gas passageway extending therethrough. The ball may be maintained in contact with both the first and second rims by a resiliency of the flexible member.
摘要翻译：提供了一种用于调节气体输送掩模的系统。该系统可以包括第一壳体部分，通过柔性构件柔性地联接到第一壳体部分的第一轮缘，联接到第一壳体部分的第二壳体部分，与第二壳体部分相关联的第二轮缘和可旋转地设置的球在第一和第二边缘之间并且具有延伸穿过其中的气体通道。可以通过柔性构件的弹性将球保持与第一和第二边缘两者接触。

65. 发明授权

US07393640B2 Terminal-phosphate-labeled nucleotides with new linkers 有权
标题翻译：末端磷酸酯标记的核苷酸与新的接头
公开(公告)号：US07393640B2
公开(公告)日：2008-07-01
申请号：US10772996
申请日：2004-02-05
申请人： Shiv Kumar , Mark McDougall , Anup Sood , John Nelson , Carl Fuller , John Macklin , Paul Mitsis
发明人： Shiv Kumar , Mark McDougall , Anup Sood , John Nelson , Carl Fuller , John Macklin , Paul Mitsis
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C07H19/10 , C07H19/20 , C07H21/00 , C12P19/34
摘要： The present invention describes methods of using terminal-phosphate-labeled nucleotides in the presence of a manganese salt to enhance their substrate properties towards various enzymes. Particularly described are methods of detecting a nucleic acid in a sample, based on the use of terminal-phosphate-labeled nucleotides as substrates for nucleic acid polymerases, in the presence of a manganese salt. Further provided are manganese complexes of terminal-phosphate-labeled nucleotides as well as terminal-phosphate-labeled nucleotides with new linkers with enhanced substrate properties.
摘要翻译：本发明描述了在锰盐存在下使用末端磷酸酯标记的核苷酸以增强其对各种酶的底物性质的方法。特别描述的是在锰盐存在的情况下，基于使用末端磷酸酯标记的核苷酸作为核酸聚合酶的底物，检测样品中的核酸的方法。还提供了末端磷酸酯标记的核苷酸的锰络合物以及具有增强的底物性质的新接头的末端磷酸酯标记的核苷酸。

66. 发明授权

US07359875B1 Method for strucuring an equity issue utilizing a closed block business entity 有权
标题翻译：使用封闭式业务实体结构化股权的方法
公开(公告)号：US07359875B1
公开(公告)日：2008-04-15
申请号：US09900554
申请日：2001-07-06
申请人： Michael Millette , Michael Rotter , Shiv Kumar , Omar Javed Chaudhary , Cliff Brokaw , David Govrin
发明人： Michael Millette , Michael Rotter , Shiv Kumar , Omar Javed Chaudhary , Cliff Brokaw , David Govrin
IPC分类号： G06Q40/00
CPC分类号： G06Q40/08 , G06Q40/00 , G06Q40/04 , G06Q40/06
摘要： A method for structuring an equity issue comprising: (a) establishing a holding company as an owner of a closed block business entity, wherein the holding company is a subsidiary of a parent company and further wherein an on-going business is a subsidiary of the parent company; (b) representing an on-going business by a first class of common stock issued from the parent company; (c) issuing a second class of common stock in the parent company, wherein the second class of common stock represents an ownership interest in the closed block business entity and wherein the closed block business entity is a lower growth and lower margin business than the on-going business; and (d) classifying proceeds received from the issuance of the second class of common stock as assets of the on-going business.
摘要翻译：一种构建股权问题的方法，包括：（a）设立控股公司作为封闭式业务实体的所有者，其中该控股公司为母公司的附属公司，并且进一步其中正在进行的业务为母公司; （b）由母公司发行的第一类普通股代表正在进行的业务; （c）在母公司中发行第二类普通股，其中第二类普通股代表封闭式商业实体的所有者权益，其中封闭式块业务实体为低于上市公司的较低增长和较低保证金业务正在经营; （d）将从发行第二类普通股收到的收益分类为正在进行的业务的资产。

67. 发明申请

US20060283457A1 Ball joint for providing flexibility to a gas delivery pathway 有权
标题翻译：用于为气体输送路径提供灵活性的球形接头
公开(公告)号：US20060283457A1
公开(公告)日：2006-12-21
申请号：US11155807
申请日：2005-06-17
申请人： Brian Woodard , Ngee Lee , Edward Geiselhart , Chris Houghton , Benjamin Sun , Shiv Kumar
发明人： Brian Woodard , Ngee Lee , Edward Geiselhart , Chris Houghton , Benjamin Sun , Shiv Kumar
IPC分类号： A62B18/08 , A62B18/02
CPC分类号： A61M16/08 , A61M16/06 , A61M16/0633 , A61M16/0655 , A61M16/0683 , A61M16/0825 , Y10S128/912 , Y10T403/31 , Y10T403/315 , Y10T403/32729
摘要： A system for adjusting a gas delivery mask is provided. The system may include a first housing portion, a first rim flexibly coupled to the first housing portion by a flexible member, a second housing portion coupled to the first housing portion, a second rim associated with the second housing portion, and a ball rotatably disposed between the first and second rims and having a gas passageway extending therethrough. The ball may be maintained in contact with both the first and second rims by a resiliency of the flexible member.
摘要翻译：提供了一种用于调节气体输送掩模的系统。该系统可以包括第一壳体部分，通过柔性构件柔性地联接到第一壳体部分的第一轮缘，联接到第一壳体部分的第二壳体部分，与第二壳体部分相关联的第二轮缘和可旋转地设置的球在第一和第二边缘之间并且具有延伸穿过其中的气体通道。可以通过柔性构件的弹性将球保持与第一和第二边缘两者接触。

68. 发明授权

US07125671B2 Nucleic acid amplification with terminal-phosphate labeled nucleotides 有权
标题翻译：用磷酸末端标记的核苷酸扩增核酸
公开(公告)号：US07125671B2
公开(公告)日：2006-10-24
申请号：US10651362
申请日：2003-08-29
申请人： Anup Sood , Shiv Kumar , John Nelson , Carl Fuller , Anuradha Sekher
发明人： Anup Sood , Shiv Kumar , John Nelson , Carl Fuller , Anuradha Sekher
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6816 , C12Q1/6823 , C12Q1/6848 , C12Q1/686 , C12Q2525/101 , C12Q2521/525 , C12Q2521/101 , C12Q2565/301 , C12Q2561/113
摘要： The present invention relates generally to the use of terminal-phosphate-labeled nucleotides having three or more phosphates as substrates for nucleic acid polymerases and their use in DNA amplification. The labels employed are chemiluminescent, fluorescent, electrochemical and chromogenic moieties as well as mass tags and include those that are directly detectable, detectable after enzyme activation or feed into other processes to generate a different signal. The signal generated from the attached dyes may also be used to quantify the amount of amplification. Further provided are stabilizers that enhance the stability of terminal-phosphate labeled nucleoside polyphosphates in aqueous solutions and are useful for reducing non-enzymatic hydrolysis of these nucleotides, hence decrease background.
摘要翻译：本发明一般涉及具有三种或更多种磷酸盐的末端磷酸酯标记的核苷酸作为核酸聚合酶的底物及其在DNA扩增中的应用。使用的标记是化学发光，荧光，电化学和显色部分以及质量标签，并且包括直接可检测的标记，可在酶活化后进行或进入其它过程以产生不同信号。从连接的染料产生的信号也可用于量化扩增量。还提供了增强末端磷酸酯标记的核苷多磷酸酯在水溶液中的稳定性的稳定剂，并且可用于减少这些核苷酸的非酶水解，从而降低背景。

69. 发明授权

US07109316B2 Oligonucleotide tagged nucleoside triphosphates (OTNTPs) for genetic analysis 失效
标题翻译：寡核苷酸标记核苷三磷酸（OTNTP）用于遗传分析
公开(公告)号：US07109316B2
公开(公告)日：2006-09-19
申请号：US10226734
申请日：2002-08-23
申请人： Shiv Kumar , Anup Sood , Sudhakar Rao , John Nelson
发明人： Shiv Kumar , Anup Sood , Sudhakar Rao , John Nelson
IPC分类号： C07H21/02 , C07H21/04 , C07H19/04 , C12Q1/68
CPC分类号： C07H19/04
摘要： Oligonucleotide tagged nucleoside triphosphates, OTNTPs, which are substrates for polymerases and or terminal nucleotidyl transferases are provided as well as methods of making these OTNTPs. Further provided are OTNTPs with fluorescent dyes including energy transfer dyes, attached to the oligonucleotide chain, OTNTPs with unnatural bases incorporated in the oligonucleotide sequence and methods for incorporating these OTNTPs in DNA or RNA. Also provided are methods for using the oligonucleotides on OTNTPs for amplifying the oligo sequence on the OTNTP using an amplification method described above. Further provided are reactive bifunctional amidites, methods of making these compounds and methods for detecting single nucleotide polymorphisms using the above OTNTPs. Methods for detecting differential gene expression using the OTNTPs and methods of separating specifically modified DNA or RNA using the OTNTPs are also provided.
摘要翻译：提供了寡聚核苷酸标记的核苷三磷酸酯，OTNTP，其是用于聚合酶和末端核苷酸转移酶的底物，以及制备这些OTNTP的方法。还提供了含有荧光染料的OTNTP，其包括与寡核苷酸链连接的能量转移染料，掺入寡核苷酸序列中的非天然碱基的OTNTP以及将这些OTNTP引入DNA或RNA中的方法。还提供了使用寡核苷酸在OTNTP上使用上述扩增方法在OTNTP上扩增寡核苷酸序列的方法。还提供了反应性双官能脒，制备这些化合物的方法和使用上述OTNTP检测单核苷酸多态性的方法。还提供了使用OTNTP检测差异基因表达的方法和使用OTNTP分离特异性修饰的DNA或RNA的方法。

70. 发明授权

US07052839B2 Terminal-phosphate-labeled nucleotides and methods of use 有权
公开(公告)号：US07052839B2
公开(公告)日：2006-05-30
申请号：US10113030
申请日：2002-04-01
申请人： John Nelson , Carl Fuller , Anup Sood , Shiv Kumar
发明人： John Nelson , Carl Fuller , Anup Sood , Shiv Kumar
IPC分类号： C12Q1/68
CPC分类号： C07H19/10 , C07H19/20 , C07H21/00 , C12Q1/6816 , C12Q1/6851
摘要： The present invention describes methods of detecting a nucleic acid in a sample, based on the use of terminal-phosphate-labeled nucleotides as substrates for nucleic acid polymerases. The methods provided by this invention utilize a nucleoside polyphosphate, dideoxynucleoside polyphosphate, or deoxynucleoside polyphosphate analogue which has a colorimetric dye, chemiluminescent, or fluorescent moiety, a mass tag or an electrochemical tag attached to the terminal-phosphate. When a nucleic acid polymerase uses this analogue as a substrate, an enzyme-activatable label would be present on the inorganic polyphosphate by-product of phosphoryl transfer. Cleavage of the polyphosphate product of phosphoryl transfer via phosphatase leads to a detectable change in the label attached thereon. When the polymerase assay is performed in the presence of a phosphatase, there is provided a convenient method for real-time monitoring of DNA or RNA synthesis and detection of a target nucleic acid.

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