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61. 发明申请

US20070059760A1 Multi-featured arrays with reflective coating 审中-公开
标题翻译：具有反光涂层的多功能阵列
公开(公告)号：US20070059760A1
公开(公告)日：2007-03-15
申请号：US11599523
申请日：2006-11-13
申请人： Andreas Dorsel , David King , Nicholas Sampas
发明人： Andreas Dorsel , David King , Nicholas Sampas
IPC分类号： C12Q1/68 , C12M1/34
CPC分类号： G01N21/6452 , G01N21/6428
摘要： A method and apparatus of interrogating an addressable array unit, which includes a substrate, a light reflecting layer on a front side of the substrate, and a plurality of features on a front side of the array. The method may include, for each of multiple features, illuminating the feature simultaneously with reflected and non-reflected interrogating light. A light emitted from respective features is detected. Either or both, constructive interference of interrogating light at the features, or constructive interference of light emitted from the features, can be obtained to allow lowering of light power from the source, enhanced signal, or reduced noise, or combinations of the foregoing. High depth discrimination may also be obtained without the need for a confocal detection system with conventional pinhole.
摘要翻译：一种询问可寻址阵列单元的方法和装置，其包括基板，在基板的前侧上的光反射层，以及阵列的前侧上的多个特征。对于多个特征中的每一个，该方法可以包括与反射和未反射的询问光同时照亮特征。检测从各个特征发射的光。可以获得在特征中询问光的建构性干扰或从特征发射的光的建构性干扰，以允许降低源的光功率，增强的信号或降低的噪声或前述的组合。也可以获得高深度鉴别，而不需要具有常规针孔的共焦检测系统。

62. 发明授权

US07112111B1 Closed loop buoyancy system 失效
标题翻译：闭环浮力系统
公开(公告)号：US07112111B1
公开(公告)日：2006-09-26
申请号：US11318002
申请日：2005-12-22
申请人： David King
发明人： David King
IPC分类号： B63B22/20
CPC分类号： B63G8/001 , B63B1/00 , B63B7/00
摘要： A closed loop buoyancy system wherein a device housing the system is submerged in a liquid filled container, the device dives to the bottom of the container, remains for a regulated amount of time, and then floats back to the surface of the liquid.
摘要翻译：闭环浮力系统，其中容纳系统的装置浸没在液体填充的容器中，该装置潜入容器的底部，保持一段规定的时间量，然后漂浮回液体的表面。

63. 发明授权

US07111483B2 Method and apparatus for fabricating helically shaped ribbons of material 有权
标题翻译：用于制造螺旋状材料带的方法和装置
公开(公告)号：US07111483B2
公开(公告)日：2006-09-26
申请号：US10666391
申请日：2003-09-19
申请人： David King , John Deibert , Gerald Ziolkowski , Jeffrey G. Cotter
发明人： David King , John Deibert , Gerald Ziolkowski , Jeffrey G. Cotter
IPC分类号： B21B15/02
CPC分类号： B21D11/14 , F28F13/12
摘要： Apparatus and methods are utilized to form turbulators. The apparatus includes a first mechanism for accepting a ribbon of material along an axis, a second mechanism for rotating an end of the ribbon of material, and a third mechanism for moving the second mechanism substantially parallel to the axis. The third mechanism is configured to operate independently from the operation of the second mechanism.
摘要翻译：利用装置和方法来形成湍流器。该装置包括用于沿轴线接收材料带的第一机构，用于旋转材料带的端部的第二机构和用于使第二机构基本上平行于轴线移动的第三机构。第三机构被配置为独立于第二机构的操作而操作。

64. 发明申请

US20060177367A1 Octahedral molecular sieve sorbents and catalysts 失效
标题翻译：八面体分子筛吸附剂和催化剂
公开(公告)号：US20060177367A1
公开(公告)日：2006-08-10
申请号：US11347459
申请日：2006-02-03
申请人： Liyu Li , David King
发明人： Liyu Li , David King
IPC分类号： B01D53/56
CPC分类号： B01D53/949 , B01D53/9422 , F01N3/021 , F01N3/0807 , F01N2570/04
摘要： Octahedral molecular sieve sorbents and catalysts are disclosed, including silver hollandite and cryptomelane. These materials can be used, for example, to catalyze the oxidation of COx (e.g., CO), NOx (e.g., NO), hydrocarbons (e.g., C3H6) and/or sulfur-containing compounds. The disclosed materials also may be used to catalyze other reactions, such as the reduction of NO2. In some cases, the disclosed materials are capable of sorbing certain products from the reactions they catalyze. Silver hollandite, in particular, can be used to remove a substantial portion of certain sulfur-containing compounds from a gas or liquid by catalysis and/or sorption. The gas or liquid can be, for example, natural gas or a liquid hydrocarbon.
摘要翻译：公开了八面体分子筛吸附剂和催化剂，包括银胡萝卜素和cryptomelane。这些材料可以用于例如催化CO 2（例如CO），NO x（例如NO），烃（例如，C 和/或含硫化合物。所公开的材料也可用于催化其它反应，例如NO 2的还原。在一些情况下，所公开的材料能够从它们催化的反应中吸收某些产物。特别地，银矿砂可以用于通过催化和/或吸附从气体或液体中除去大部分某些含硫化合物。气体或液体可以是例如天然气或液体烃。

65. 发明申请

US20060072373A1 Amplitude preserving prestack migration method 有权
标题翻译：幅值保留叠前偏移法
公开(公告)号：US20060072373A1
公开(公告)日：2006-04-06
申请号：US10958522
申请日：2004-10-04
申请人： Seongbok Lee , David King
发明人： Seongbok Lee , David King
IPC分类号： G01V1/00
CPC分类号： G01V1/28 , G01V2210/51
摘要： A method is disclosed for amplitude preserving Kirchhoff time migration. The method includes calculating estimates of the geometrical spreading terms using a constant velocity approximation. Takeoff and emergence angles are accurately calculated based on a model of velocity which varies with respect to travel time. An image can be calculated at at least one travel time using the estimated weights and calculated takeoff and emergence angles.
摘要翻译：公开了一种用于振幅保持基尔霍夫时间偏移的方法。该方法包括使用恒速近似来计算几何扩展项的估计。基于相对于行驶时间变化的速度模型，精确地计算起飞和起飞角度。可以使用估计的权重和计算的起飞和出现角度，在至少一个行进时间计算图像。

66. 发明申请

US20060070547A1 Electronic safety and arming unit 有权
标题翻译：电子安全和布防单位
公开(公告)号：US20060070547A1
公开(公告)日：2006-04-06
申请号：US10548427
申请日：2004-03-05
申请人： David Combes , David King
发明人： David Combes , David King
IPC分类号： F42C15/34
CPC分类号： F42C15/40 , F42C15/34
摘要： An electronic safety and arming unit comprises a micro electromechanical system (MEMS) shutter device. The shutter (18) is suspended by thin lightweight arms and hinges, all formed by silicon processing of SOI substrates and includes holding latches for holding the shutter (18) in the closed position. The holding latches may be released by an electrothermal actuator. The shutter (18) separates an initiator section from an explosive train (6) of munitions such as shells, thereby providing safety until the shell is fired and away from its start point. After firing, the shutter (18) is opened ready for the main explosive to be detonated by the initiator (3). The shutter (18) may be suspended by a compliant displacement multiplier and may include an electrothermal actuator such as an electrically heatable bent beam. Heating of the beam causes movement of a shutter blade from a shut condition covering a firing aperture to an open condition. Alternatively the shutter (18) may operate by inertial centrifugal forces generated by a spinning munition. The shutter (18) may include latches for retaining the shutter in its open position.
摘要翻译：电子安全和布防装置包括微机电系统（MEMS）快门装置。闸门（18）由薄的轻质臂和铰链悬挂，全部由SOI基板的硅加工形成，并且包括用于将挡板（18）保持在关闭位置的保持闩锁。保持闩锁可以由电热致动器释放。挡板（18）将起动器部分与诸如壳的弹药的爆炸火车（6）分开，从而提供安全性，直到壳体被击发并远离其起点。在点火之后，快门（18）打开准备好，主要的爆炸物被起动器（3）引爆。快门（18）可以由顺应性位移乘数悬挂，并且可以包括电热致动器，例如电可加热弯曲梁。梁的加热导致快门叶片从覆盖击球孔的关闭状态移动到打开状态。或者，快门（18）可以通过由旋转弹药产生的惯性离心力来操作。快门（18）可以包括用于将快门保持在其打开位置的闩锁。

67. 发明申请

US20050208041A1 Humanized antibodies to interferon alpha receptor-1 (IFNAR-1) 有权
标题翻译：干扰素α受体-1（IFNAR-1）的人源化抗体
公开(公告)号：US20050208041A1
公开(公告)日：2005-09-22
申请号：US10831459
申请日：2004-04-23
申请人： Josephine Cardarelli , Tseng-hui Chen , David King , Christopher Bebbington , Sarah Pogue , Francis Carr , Stephen Williams
发明人： Josephine Cardarelli , Tseng-hui Chen , David King , Christopher Bebbington , Sarah Pogue , Francis Carr , Stephen Williams
IPC分类号： A61K39/395 , C07K16/28 , C07K16/44 , C07K16/46
CPC分类号： C07K16/2866 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/70 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： Humanized monoclonal antibodies which bind to IFNAR-1, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the humanized antibodies and therapeutic and diagnostic methods for using the humanized antibodies.
摘要翻译：公开了结合IFNAR-1的人源化单克隆抗体以及相关的基于抗体的组合物和分子。还公开了包含人源化抗体和使用人源化抗体的治疗和诊断方法的药物组合物。

68. 发明申请

US20050169826A1 Sulfur oxide adsorbents and emissions control 失效
标题翻译：硫氧化物吸附剂和排放控制
公开(公告)号：US20050169826A1
公开(公告)日：2005-08-04
申请号：US10771866
申请日：2004-02-04
申请人： Liyu Li , David King
发明人： Liyu Li , David King
IPC分类号： B01D53/94 , B01D53/50 , B01D53/56
CPC分类号： B01D53/9431 , B01D53/949 , Y10S95/902
摘要： High capacity sulfur oxide absorbents utilizing manganese-based octahedral molecular sieve (Mn—OMS) materials are disclosed. An emissions reduction system for a combustion exhaust includes a scrubber 24 containing these high capacity sulfur oxide absorbents located upstream from a NOX filter 26 or particulate trap.
摘要翻译：公开了使用锰基八面体分子筛（Mn-OMS）材料的高容量硫氧化物吸收剂。用于燃烧排放的排放减少系统包括洗涤器24，洗涤器24包含位于NOX过滤器26或颗粒捕集器上游的这些高容量硫氧化物吸收剂。

69. 发明申请

US20050152901A1 Compositions and methods for the therapy of Inflammatory Bowel Disease 有权
标题翻译：用于治疗炎症性肠病的组合物和方法
公开(公告)号：US20050152901A1
公开(公告)日：2005-07-14
申请号：US10831432
申请日：2004-04-23
申请人： Lesley Pickford , Christopher Bebbington , Geoffrey Yarranton , David King
发明人： Lesley Pickford , Christopher Bebbington , Geoffrey Yarranton , David King
IPC分类号： C07K16/28 , A61K39/395
CPC分类号： C07K16/2866 , A61K2039/505 , C07K2317/24 , C07K2319/30
摘要： Compositions and methods for the therapy of Inflammatory Bowel Disease (IBD), including Celiac Disease, Crohn's Disease, and Ulcerative Colitis, are disclosed. Illustrative compositions comprise one or more anti-type 1 interferon antagonists, such as anti-type 1 interferon receptor antibody antagonists and fragments thereof, as well as polypeptides and small molecules that inhibit the interaction of type 1 interferon with its receptor (IFNAR).
摘要翻译：公开了用于治疗炎性肠病（IBD）的组合物和方法，包括腹腔疾病，克罗恩病和溃疡性结肠炎。示例性组合物包含一种或多种抗1型干扰素拮抗剂，例如抗1型干扰素受体抗体拮抗剂及其片段，以及抑制1型干扰素与其受体（IFNAR）相互作用的多肽和小分子。

70. 发明申请

US20050138164A1 Generic method for resource monitoring configuration in provisioning systems 失效
标题翻译：配置系统中资源监视配置的通用方法
公开(公告)号：US20050138164A1
公开(公告)日：2005-06-23
申请号：US10739438
申请日：2003-12-18
申请人： Toby Burton , Rhonda Childress , Liana Fong , Andrew Greff , Michael Kalantar , David King
发明人： Toby Burton , Rhonda Childress , Liana Fong , Andrew Greff , Michael Kalantar , David King
IPC分类号： G06F7/00 , G06F15/173 , G06F17/30 , H04L12/24
CPC分类号： H04L41/0883 , H04L41/0806 , H04L41/0856
摘要： A generic mechanism and model are provided to capture and store configuration profiles for resource monitors such that monitors can be flexibly deployed, configured, modified, and removed using appropriate sets of parameters and values. As an integral part of resource provisioning, this generic mechanism will require only a generic set of workflows and a generic data model to provision monitors. The provisioning system of the present invention captures and stores response parameters and values from monitors created during initial deployment such that these parameters can be used for later modification and removal of these monitors.
摘要翻译：提供通用机制和模型，以捕获和存储资源监视器的配置配置文件，以便可以使用适当的参数和值集灵活地部署，配置，修改和删除监视器。作为资源配置的一个组成部分，这种通用机制只需要一组通用的工作流程和通用数据模型来配置监视器。本发明的供应系统从初始部署期间创建的监视器捕获并存储响应参数和值，使得这些参数可用于稍后修改和移除这些监视器。

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