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61. 发明授权

US07544160B2 Extracardiac blood flow amplification device 失效
标题翻译：心内血流放大装置
公开(公告)号：US07544160B2
公开(公告)日：2009-06-09
申请号：US11349062
申请日：2006-02-07
申请人： Yossi Gross
发明人： Yossi Gross
IPC分类号： A61M1/12 , A61M5/14
CPC分类号： A61F2/24 , A61F2/2421 , A61F2/2469 , A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1048 , A61M1/1096 , A61M1/122 , A61M1/125 , A61M1/127
摘要： Apparatus is provided including an element shaped so as to define at least one surface. The element is adapted to be implanted in an ascending aorta of a subject in a vicinity of an aortic valve, and, during systole, to store, as potential energy, work applied to the surface by blood of the subject passing through the element. The element allows at least 75% of the blood passing into the element during systole of each cardiac cycle to exit the element during systole of the respective cardiac cycle. The element applies the stored energy to push blood towards at least one coronary artery of the subject during diastole. For some applications, the surface includes a first surface, and the element is shaped so as to define a second surface, which is configured to apply the stored energy. Other embodiments are also described.
摘要翻译：提供了包括形成为限定至少一个表面的元件的装置。该元件适于植入在主动脉瓣附近的受试者的升主动脉中，并且在收缩期间，通过穿过该元件的受试者的血液作为势能存储作用于该表面的作用。该元件允许至少75％的血液在每个心动周期的收缩期间通过元件以在相应心动周期的收缩期间离开该元件。该元件在舒张期期间施加存储的能量以将血液推向对象的至少一个冠状动脉。对于一些应用，表面包括第一表面，并且元件成形为限定第二表面，其被配置为施加存储的能量。还描述了其它实施例。

62. 发明申请

US20090093793A1 EXTERNAL DRUG PUMP 审中-公开
标题翻译：外用药泵
公开(公告)号：US20090093793A1
公开(公告)日：2009-04-09
申请号：US12244688
申请日：2008-10-02
申请人： Yossi Gross , Oz Cabiri , John Paproski , Moshe Barkan
发明人： Yossi Gross , Oz Cabiri , John Paproski , Moshe Barkan
IPC分类号： A61M5/31 , A61M5/315
CPC分类号： A61M5/31596 , A61M5/1413 , A61M5/14248 , A61M5/1452 , A61M5/1456 , A61M5/14566 , A61M5/158 , A61M5/16827 , A61M5/172 , A61M5/1723 , A61M5/3146 , A61M2005/14252 , A61M2005/1426 , A61M2005/14268 , A61M2005/14533 , A61M2005/31518 , A61M2205/3523 , A61M2205/3569 , F16H25/12 , Y10T74/18576
摘要： Apparatus is described for administering a substance to a subject. A vial contains the substance, an inner surface of the vial being shaped to define a protrusion therefrom. A stopper within the vial is slidably coupled to the vial. A first threaded element is (a) rotatable and (b) substantially immobile proximally with respect to the vial during rotation of the first threaded element. A second threaded element is threadedly coupled to the first threaded element. The protrusion impedes rotation of the second threaded element with respect to the vial. The distal end of the second threaded element remains proximal to a distal end of the stopper during rotation of the first threaded element. The first threaded element, by rotating, linearly advances the stopper and the second threaded element toward a distal end of the vial. Other embodiments are also described.
摘要翻译：描述了用于向受试者施用物质的装置。小瓶包含物质，小瓶的内表面成形为从其中限定突起。小瓶内的塞子可滑动地联接到小瓶。第一螺纹元件是（a）可旋转并且（b）在第一螺纹元件旋转期间相对于小瓶在近侧基本上不可移动。第二螺纹元件螺纹连接到第一螺纹元件。突起阻止第二螺纹元件相对于小瓶的旋转。第二螺纹元件的远端在第一螺纹元件旋转期间保持靠近止动件的远端。第一螺纹元件通过旋转线性地使塞子和第二螺纹元件朝向小瓶的远端前进。还描述了其它实施例。

63. 发明申请

US20090093758A1 Fibroid treatment apparatus and method 审中-公开
标题翻译：纤维治疗仪及方法
公开(公告)号：US20090093758A1
公开(公告)日：2009-04-09
申请号：US11591044
申请日：2006-10-31
申请人： Yossi Gross
发明人： Yossi Gross
IPC分类号： A61M29/02
CPC分类号： A61M25/10 , A61B17/12009 , A61B17/42 , A61B2017/22067 , A61M25/1002 , A61M2025/0002 , A61M2025/0037 , A61M2025/0197 , A61M2025/105 , A61M2025/1052 , A61M2025/1054 , A61M2025/1061
摘要： Apparatus is provided, including a tube that is passed into a patient's vagina and to penetrate vaginal tissue until a distal tip of the tube is outside of a uterine artery of the patient, but in a vicinity of a portion of the uterine artery that supplies a uterine fibroid. A balloon, disposed at the distal tip, is inflated to cause local squeezing of the portion of the uterine artery to an extent sufficient to occlude the uterine artery. Other embodiments are also described.
摘要翻译：提供了一种装置，其包括通过病人的阴道并穿透阴道组织的管，直到管的远侧末端在患者的子宫动脉之外，而在子宫动脉的一部分附近，子宫肌瘤。设置在远端的气囊被充气以使子宫动脉的局部部分挤压至足以闭塞子宫动脉的程度。还描述了其它实施例。

64. 发明申请

US20080319287A1 Implantable Power Sources and Sensors 有权
标题翻译：可植入电源和传感器
公开(公告)号：US20080319287A1
公开(公告)日：2008-12-25
申请号：US11632587
申请日：2005-07-13
申请人： Yossi Gross , Ben-Tsion Williger , Tehila Hyman , Tova Neufeld
发明人： Yossi Gross , Ben-Tsion Williger , Tehila Hyman , Tova Neufeld
IPC分类号： A61B5/145 , G01N33/66 , C12Q1/37 , A61M5/00 , C12Q1/54
CPC分类号： C07K14/43595 , A61B5/14532 , A61K49/0045 , A61K49/0047 , A61K49/0056 , C07K2319/60 , G01N33/54373
摘要： A protein is provided, including a glucose binding site, cyan fluorescent protein (CFP), and yellow fluorescent protein (YFP). The protein is configured such that binding of glucose to the glucose binding site causes a reduction in a distance between the CFP and the YFP. Substance monitoring apparatus (210) is also provided, including a semi-permeable barrier (212), adapted to be implanted in a body of a subject and to allow passage therethrough of a substance, while inhibiting passage therethrough of immune cells; and microorganisms (214), disposed within the semi-permeable barrier (212) so as to produce a measurable response to a level of the substance. A sensor (220) is adapted to measure the measurable response and not to measure a response of any mammalian cells that may be disposed within the semi-permeable barrier (212).
摘要翻译：提供蛋白质，包括葡萄糖结合位点，青色荧光蛋白（CFP）和黄色荧光蛋白（YFP）。配置蛋白质使得葡萄糖与葡萄糖结合位点的结合导致CFP和YFP之间的距离减小。还提供了物质监测设备（210），其包括半渗透屏障（212），其适于植入受试者体内并允许物质通过，同时抑制免疫细胞通过; 和微生物（214），其设置在半渗透屏障（212）内，以便产生对物质水平的可测量响应。传感器（220）适于测量可测量的响应并且不测量可以设置在半渗透屏障（212）内的任何哺乳动物细胞的响应。

65. 发明申请

US20080234537A1 Extracardiac Blood Flow Amplification Device 有权
标题翻译：心内血流扩张装置
公开(公告)号：US20080234537A1
公开(公告)日：2008-09-25
申请号：US11921401
申请日：2005-02-10
申请人： Yossi Gross
发明人： Yossi Gross
IPC分类号： A61M1/10
CPC分类号： A61F2/02 , A61F2002/068 , A61M1/1008 , A61M1/1037 , A61M1/106 , A61M1/1072 , A61M1/1096 , A61M1/122
摘要： Apparatus (10) is provided including a first chamber (20) and a second chamber (22), adapted to be in fluid communication with a first volume and a second volume of oxygenated blood of a subject, respectively, the first chamber (20) and the second chamber (22) having a first surface (34) and a second surface (36), respectively. The apparatus (10) further includes a third surface (38) adapted to apply an elastically-derived force, at least a first portion of the third surface (38) in mechanical communication with the first surface (34), and at least a second portion of the third surface (38) in mechanical communication with the second surface (36) during at least a portion of a cardiac cycle. A pressure-sensitive valve (46) is coupled between the first chamber (20) and the second chamber (22), the valve (46) adapted: (a) to be in an open position during at least a portion of systole, such that the first chamber (20) is in fluid communication with the second chamber (22) and the first volume is in fluid communication with the second volume; and (b) to be in a substantially closed position during diastole, such that the first chamber (20) is substantially not in fluid communication with the second chamber (22) and the first volume is substantially not in fluid communication with the second volume. Other embodiments are also described.
摘要翻译：提供了装置（10），其包括第一室（20）和第二室（22），其适于分别与受试者的第一体积和第二体积的含氧血液流体连通，第一室（20）并且所述第二室（22）分别具有第一表面（34）和第二表面（36）。所述设备（10）还包括适于施加弹性导出力的第三表面（38），所述第三表面（38）的至少第一部分与所述第一表面（34）机械连通，并且至少第二表面所述第三表面（38）的部分在心动周期的至少一部分期间与所述第二表面（36）机械连通。压敏阀（46）联接在第一室（20）和第二室（22）之间，阀（46）适于：（a）在至少一部分收缩期间处于打开位置，所述第一室（20）与所述第二室（22）流体连通，并且所述第一容积与所述第二容积流体连通; 和（b）在舒张期间处于基本上闭合的位置，使得第一腔室（20）基本上不与第二腔室（22）流体连通，并且第一容积基本上不与第二容积流体连通。还描述了其它实施例。

66. 发明申请

US20080151175A1 ELECTRONIC TRANSPARENCY REGULATION ELEMENT TO ENHANCE VIEWING THROUGH LENS SYSTEM 有权
标题翻译：电子透明度调节元件可以通过镜头系统进行查看
公开(公告)号：US20080151175A1
公开(公告)日：2008-06-26
申请号：US11740582
申请日：2007-04-26
申请人： Yossi Gross
发明人： Yossi Gross
IPC分类号： G02C7/10 , G02C7/02 , G02C7/14
CPC分类号： G02C7/086 , G02C7/088 , G02C7/105 , G02C7/14 , G02C7/16 , G02C11/12
摘要： Apparatus is provided including a frame configured to be worn on a face, such that a portion of the frame is located in front of a first eye and not in front of a second eye. The apparatus also includes a first lens, including one or more first lenses, coupled to the portion of the frame, and a second lens system, including one or more second lenses, coupled to the portion. A transparency regulation element coupled to the first lens system has variable transparency, and is configured to enhance viewing through the second lens system. A power unit is configured to drive the transparency regulation element to darken the first lens system without substantially darkening at least a portion of the second lens system during a first period, and, during a second period after the first period, to not drive the transparency regulation element to darken the first lens system.
摘要翻译：提供了包括被配置为佩戴在脸部上的框架的框架，使得框架的一部分位于第一眼睛的前面而不在第二只眼睛的前方。该装置还包括第一透镜，包括耦合到框架的该部分的一个或多个第一透镜，以及耦合到该部分的包括一个或多个第二透镜的第二透镜系统。耦合到第一透镜系统的透明度调节元件具有可变的透明度，并且被配置为增强通过第二透镜系统的观看。功率单元被配置为驱动透明度调节元件使第一透镜系统变暗，而在第一时间段内基本上不会使第二透镜系统的至少一部分变暗，并且在第一周期之后的第二周期期间，不驱动透明度调节元件使第一透镜系统变暗。

67. 发明申请

US20080015667A1 Peltier unidirectional and selective nerve stimulation 失效
标题翻译：帕尔帖单向和选择性神经刺激
公开(公告)号：US20080015667A1
公开(公告)日：2008-01-17
申请号：US11487012
申请日：2006-07-13
申请人： Yossi Gross
发明人： Yossi Gross
IPC分类号： A61F7/12 , F25B21/02
CPC分类号： A61F7/12 , A61F2007/0075 , A61F2007/126 , F25B21/02
摘要： Apparatus is provided including an assembly (22) and a control unit (36). The assembly (22) includes a housing (34) configured to be applied to a nerve (20) of a subject, and at least one cathode (30) and at least one Peltier cooler (32), which are fixed to the housing (34). The control unit (36) is configured to drive the cathode (30) to apply an activating current to the nerve (20) that generates action potentials traveling in first and second directions (38 and 40) in the nerve (20), and the Peltier cooler (32) to cool the nerve (20) sufficiently to block propagation of at least a portion of the cathode-generated action potentials traveling in the second direction (40). Other embodiments are also described.
摘要翻译：提供了包括组件（22）和控制单元（36）的设备。组件（22）包括构造成施加到受试者的神经（20）的壳体（34）和至少一个阴极（30）和至少一个珀尔帖冷却器（32），固定到壳体 34）。控制单元（36）被配置为驱动阴极（30）向神经（20）施加激活电流，所述神经（20）产生在神经（20）中的第一和第二方向（38和40）上行进的动作电位，并且珀尔帖冷却器（32）以充分地冷却神经（20）以阻止至少一部分在第二方向（40）上行进的阴极产生动作电位的传播。还描述了其它实施例。

68. 发明申请

US20070276483A1 DOUBLE INSERTION INTRAOCULAR IMPLANT 有权
标题翻译：双插入腔内植入物
公开(公告)号：US20070276483A1
公开(公告)日：2007-11-29
申请号：US11420327
申请日：2006-05-25
申请人： Eli Aharoni , Yossi Gross
发明人： Eli Aharoni , Yossi Gross
IPC分类号： A61F2/16
CPC分类号： A61F2/1648 , A61F2/1651 , A61F2002/1699 , A61F2250/0053
摘要： An intraocular telescopic lens assembly including a negative lens having a negative lens optical axis, a positive lens having a positive lens optical axis and a spacer disposed intermediate the negative lens and the positive lens, the spacer being operative to maintain mutual orientation of the negative lens and the positive lens such that the negative lens optical axis is coaxial with the positive lens optical axis.
摘要翻译：一种眼内望远镜透镜组件，包括具有负透镜光轴的负透镜，具有正透镜光轴的正透镜和设置在负透镜和正透镜之间的间隔件，间隔件可操作以保持负透镜的相互取向和正透镜，使得负透镜光轴与正透镜光轴同轴。

69. 发明申请

US20070072153A1 Photo-sterilization 审中-公开
标题翻译：照相灭菌
公开(公告)号：US20070072153A1
公开(公告)日：2007-03-29
申请号：US10564165
申请日：2004-07-11
申请人： Yossi Gross , Daniel Better , Baruch Levy , Dvir Keren
发明人： Yossi Gross , Daniel Better , Baruch Levy , Dvir Keren
IPC分类号： A61C5/02
CPC分类号： A61N5/0624 , A61C5/40 , A61C5/50 , A61C19/003 , A61N5/0603 , A61N2005/0606 , A61N2005/0631 , A61N2005/0659 , A61N2005/0661 , A61N2005/0662 , A61N2005/067
摘要： The present invention provides substances, devices, methods, and kits for photo-sterilization of a root canal, prior to and when performing endodontics, as well as periodically as post-endodontic prophylactic measures. The root-canal filling includes a light-transmitting element, operative as a diffuser, and methods are provided for communicating light to the diffuser, for disinfecting the walls of the root canals, by photo sterilization. The diffuser may be formed of silicone polymers, synthetic fused silica, quartz or the like, and may be surrounded by a light-transmitting sealer. The diffuser may be incorporated with an endodontic post, or a specially designed post, which may be transparent and (or) hollow. In a preferred embodiment, the diffuser is formed of a light transmitting conical shell of Cyclic Olefin Copolymers (COC), filled with a fluid such as air, distilled water, or silicone oil.
摘要翻译：本发明提供了在进行牙髓治疗之前和期间根管根管的光消毒的物质，装置，方法和试剂盒，以及周期性地作为根治后预防措施。根管填充物包括作为扩散器操作的透光元件，并且提供了用于将光传播到扩散器的方法，用于通过光杀菌来消毒根管壁。扩散器可以由硅氧烷聚合物，合成熔融石英，石英等形成，并且可以由透光封闭器包围。扩散器可以与可以是透明的（或）中空的根管柱或特殊设计的柱结合。在优选实施例中，扩散器由填充有诸如空气，蒸馏水或硅油的流体的环状烯烃共聚物（COC）的透光锥形壳形成。

70. 发明申请

US20050062679A1 Intraocular implants 有权
公开(公告)号：US20050062679A1
公开(公告)日：2005-03-24
申请号：US10982987
申请日：2004-11-04
申请人： Eli Aharoni , Gideon Dotan , Ruti Alon , Yossi Gross
发明人： Eli Aharoni , Gideon Dotan , Ruti Alon , Yossi Gross
IPC分类号： A61F2/16 , A61F9/08 , A61N1/36 , G09G5/00 , G09G3/34
CPC分类号： A61F9/08 , A61F2/14 , A61F2/1648 , A61F2/1651 , A61F2250/0053 , A61F2250/0069 , A61N1/36046
摘要： An artificial vision system including a sealed capsule adapted for intraocular placement upstream of a retina, an electronic display located within the sealed capsule and focusing optics located within the sealed capsule and arranged for focusing an image on the electronic display onto the retina.

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