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61. 发明申请

US20050065099A1 Treatment of mitochondrial diseases 审中-公开
标题翻译：治疗线粒体疾病
公开(公告)号：US20050065099A1
公开(公告)日：2005-03-24
申请号：US10941126
申请日：2004-09-15
申请人： Gail Walkinshaw , Sekhar Bodupalli , Bing Wang , Guy Miller
发明人： Gail Walkinshaw , Sekhar Bodupalli , Bing Wang , Guy Miller
IPC分类号： A61K31/353 , A61K31/675 , A61K31/7048 , C07D311/74 , C07D311/94 , C07D319/08 , C07D405/06 , C07D405/12 , C07D405/14 , C07D409/04 , C07D417/06 , C07D417/12
CPC分类号： A61K31/352 , A61K31/353 , A61K31/357 , A61K31/496 , A61K31/675 , A61K31/7048 , C07D295/096 , C07D311/58 , C07D311/70 , C07D311/74 , C07D311/94 , C07D319/08 , C07D405/06 , C07D405/12 , C07D405/14 , C07D409/04 , C07D417/06 , C07D417/12
摘要： The invention relates the method of treatment or amelioration of mitochondrial disorders such as Alzheimer's disease, Parkinson's disease, Friedreich's ataxia (FRDA), cerebellar ataxias, Leber's hereditary optic neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), Myoclonic Epilepsy with Ragged Red Fibers (MERFF), amyotrophic lateral sclerosis (ALS), motor neuron diseases, Huntington's disease, macular degeneration, and epilepsy, with chroman derivatives of Formula I or Formula II as described herein.
摘要翻译：本发明涉及线粒体疾病如阿尔茨海默病，帕金森病，弗里德里希共济失调（FRDA），小脑共济失调，莱伯氏遗传性视神经病变（LHON），线粒体肌病，脑病，乳酸酸中毒，中风（MELAS），肌阵挛具有褴褛红色纤维（MERFF）的癫痫，肌萎缩性侧索硬化（ALS），运动神经元疾病，亨廷顿氏病，黄斑变性和癫痫，与本文所述的式I或式II的苯并二氢吡喃衍生物。

62. 发明申请

US20050032751A1 Methods for treatment of dermatological conditions 失效
标题翻译：皮肤病学治疗方法
公开(公告)号：US20050032751A1
公开(公告)日：2005-02-10
申请号：US10910095
申请日：2004-08-02
申请人： Bing Wang , Sekhar Boddupalli , Xiangfeng Li , Khalid Mahmood , Wei Zhang , Guy Miller
发明人： Bing Wang , Sekhar Boddupalli , Xiangfeng Li , Khalid Mahmood , Wei Zhang , Guy Miller
IPC分类号： A61K8/44 , A61K8/49 , A61K31/135 , A61K31/195 , A61K31/40 , A61K31/44 , A61K31/66 , A61K45/06 , A61Q19/00 , A61Q19/08
CPC分类号： A61K45/06 , A61K8/44 , A61K8/49 , A61K8/498 , A61K31/135 , A61K31/195 , A61K31/40 , A61K31/44 , A61K31/66 , A61Q19/00 , A61Q19/08 , A61K2300/00
摘要： A method of reducing the appearance of skin conditions associated with loss of skin tightness, skin firmness, or dark circles under the eyes with topical compositions comprising compounds of any of the Formulae I or Ia as described herein, is disclosed.
摘要翻译：公开了一种减少与包含本文所述的包含本文所述的任何式I或Ia的化合物的局部组合物在眼睛下的皮肤紧致性，皮肤紧致度或黑眼圈丧失相关的皮肤状况的外观的方法。

63. 发明申请

US20050003117A1 Low-temperature press process for making insulating glass assemblies 有权
标题翻译：制造绝缘玻璃组件的低温压制工艺
公开(公告)号：US20050003117A1
公开(公告)日：2005-01-06
申请号：US10798590
申请日：2004-03-11
申请人： Bing Wang , John Greenzweig , Mark Hackbarth
发明人： Bing Wang , John Greenzweig , Mark Hackbarth
IPC分类号： B32B17/10 , C03C27/10 , E06B3/24 , E06B3/56 , E06B3/663
CPC分类号： C03C27/10 , Y02A30/25 , Y02B80/24
摘要： A process for making an insulating glass assembly is disclosed, the process including applying a sealant composition to a surface of a spacer; contacting the sealant composition with a glass pane, and applying pressure on the glass pane to bond the glass pane to the spacer through the sealant composition, the pressure being applied at an ambient temperature of from about 15° C. to about 60° C.
摘要翻译：公开了制造绝缘玻璃组件的方法，该方法包括将密封剂组合物施加到间隔物的表面上; 使密封剂组合物与玻璃板接触，并在玻璃板上施加压力以通过密封剂组合物将玻璃板粘合到间隔件上，该压力在约15℃至约60℃的环境温度下施加。

64. 发明授权

US06653346B1 Cytoprotective benzofuran derivatives 失效
标题翻译：细胞保护性苯并呋喃衍生物
公开(公告)号：US06653346B1
公开(公告)日：2003-11-25
申请号：US10361141
申请日：2003-02-06
申请人： Bing Wang , Jian Chen
发明人： Bing Wang , Jian Chen
IPC分类号： A61K3134
CPC分类号： C07D307/79 , C07D307/80 , C07D307/81 , C07D307/83 , C07D307/84 , C07D307/85 , C07D413/04 , C07D493/04
摘要： Cytoprotective compounds, many of which are benzofuran derivatives are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
摘要翻译：其中许多是苯并呋喃衍生物的细胞保护化合物可用于治疗某些缺血性或炎症性疾病，包括但不限于中风，心肌梗死，充血性心力衰竭和以炎症或氧化损伤为特征的皮肤病症。它们也可用于制备用于治疗这些病症的药物和化妆品制剂。

65. 发明授权

US06608196B2 Process for solid supported synthesis of pyruvate-derived compounds 失效
公开(公告)号：US06608196B2
公开(公告)日：2003-08-19
申请号：US10138032
申请日：2002-05-03
申请人： Bing Wang , Satyanarayana Janagani , Wyeth B. Callaway , Jonathan L. Sessler
发明人： Bing Wang , Satyanarayana Janagani , Wyeth B. Callaway , Jonathan L. Sessler
IPC分类号： C07D41300
CPC分类号： C07D295/185 , A61K31/16 , A61K31/215 , A61K31/223 , A61K38/00 , C07C249/12 , C07C319/20 , C07D207/22 , C07D207/24 , C07D211/62 , C07D211/74 , C07D211/78 , C07D217/04 , C07D233/84 , C07D295/13 , C07D295/15 , C07K5/0215 , C07K5/0819 , C07C251/60 , C07C323/57 , C07C323/60
摘要： Provided are processes for synthesizing structurally diverse pyruvate-derived compounds using a parallel approach on a solid phase support. Examples of such a solid phase support include resins which have also been used in solid phase peptide synthesis.

66. 发明授权

US5143988A High refractive-index hybrid material prepared by titanium alkoxide and a phosphine containing oligomer 失效
$High refractive-index hybrid material prepared by titanium alkoxide and a phosphine containing oligomer$
标题翻译：由钛醇盐和含膦低聚物制备的高折射率杂化材料
公开(公告)号：US5143988A
公开(公告)日：1992-09-01
申请号：US552634
申请日：1990-07-13
申请人： Bing Wang , Garth L. Wilkes
发明人： Bing Wang , Garth L. Wilkes
IPC分类号： C04B28/00 , C08G65/48 , C08G79/00 , G02B1/04
CPC分类号： C08G79/00 , C04B28/003 , C08G65/48 , G02B1/04
摘要： New hybrid materials have been prepared by combining a titanium alkoxide sol with high a refractive index phosphine oxide-containing oligomeric component (triethoylsilane-capped poly(arylene ether phosphine oxide). These materials are prepared by the sol-gel method. The final products are transparent and display high refractive index (n.sub.D =1.66-1.80). The refractive index of these hybrid materials display a linear relationship with titanium oxide content.
摘要翻译：通过将烷氧基钛溶胶与高折射率含氧化膦的低聚成分（三丁基硅烷封端的聚（亚芳基醚氧化膦））结合制备新的杂化材料，这些材料通过溶胶 - 凝胶法制备，最终产物为透明度高，折射率高（nD = 1.66〜1.80），折射率与氧化钛含量呈线性关系。

67. 发明申请

US20220026249A1 DEVICE AND METHOD FOR DETECTING A BLOCKAGE POSITION IN A PIPELINE 有权
公开(公告)号：US20220026249A1
公开(公告)日：2022-01-27
申请号：US16936422
申请日：2020-07-23
申请人： Guo-Hao Wang , Bing Wang , Kuo-Hsin Chang , Chung-Ping Lai
发明人： Guo-Hao Wang , Bing Wang , Kuo-Hsin Chang , Chung-Ping Lai
IPC分类号： G01F1/56 , F17D3/01 , G08C17/02
摘要： A device and a method for detecting a blockage position in a pipeline by RFID technology is disclosed. An RFID tag is disposed in a pipe of a pipeline first, the RFID tag is read with a predetermined single or double frequencies, and finally whether the position of the pipe at which the RFID tag is located is blocked or not can be judged by the difference between the echo signals sent from the RFID tag. By the RFID technology, a contactless and non-destructive approach of detecting a blockage in a pipeline is implemented.

68. 发明授权

US09465417B2 Cluster system, method and device for expanding cluster system 有权
标题翻译：集群系统，扩展集群系统的方法和装置
公开(公告)号：US09465417B2
公开(公告)日：2016-10-11
申请号：US13096588
申请日：2011-04-28
申请人： Jianbo Zhu , Lingqiang Fan , Bing Wang
发明人： Jianbo Zhu , Lingqiang Fan , Bing Wang
IPC分类号： G06F11/20 , H04L12/26 , H04L12/775 , G06F1/18 , G06F1/26
CPC分类号： G06F1/189 , G06F1/26 , G06F11/2007 , G06F11/2035 , H04L43/0811 , H04L45/58
摘要： A method for expanding a cluster system is provided. The cluster system includes at least one Cluster Central Chassis (CCC), and a newly-added Cluster Line-card Chassis (CLC) connected with the CCC to form the cluster system. The method includes the following steps. A control plane is established. An equipment management right is switched to the CCC, so that the CCC manages the newly-added CLC. Meanwhile, a cluster line-card device, a cluster central exchange device, and a cluster system are further provided. In implementation, smooth expansion can be achieved without interrupting running equipment services in the CLC current network and without interrupting data services. Moreover, during the expansion process, hardware equipment needs not to be replaced, thus investment of users on the equipment is reduced.
摘要翻译：提供了一种用于扩展集群系统的方法。集群系统包括至少一个集群中心机箱（CCC）和与CCC连接的新增的集群线路卡机箱（CLC），以形成集群系统。该方法包括以下步骤。建立一个控制平面。设备管理权转用CCC，CCC管理新增的CLC。同时，还提供集群线路卡设备，集群中央交换设备和集群系统。在实施中，可以实现平滑扩展，而不会中断CLC当前网络中的运行设备服务，而不会中断数据服务。此外，在扩展过程中，硬件设备不需要更换，用户对设备的投资减少。

69. 发明授权

US09411656B2 Load balance connections per server in multi-core/multi-blade system 有权
标题翻译：多核/多刀片系统中每个服务器的负载平衡连接
公开(公告)号：US09411656B2
公开(公告)日：2016-08-09
申请号：US12489366
申请日：2009-06-22
申请人： Avinash Jindal , Deepak Bansal , Sam Htin Moy , David Cheung , Bing Wang , Mani Kancherla , Sridhar Devarapalli
发明人： Avinash Jindal , Deepak Bansal , Sam Htin Moy , David Cheung , Bing Wang , Mani Kancherla , Sridhar Devarapalli
IPC分类号： G06F15/173 , G06F9/50
CPC分类号： G06F9/5083
摘要： A network device includes a plurality of blades, each having a plurality of CPU cores that process requests received by the network device. Each blade further includes an accumulator circuit. Each accumulator circuit periodically aggregates the local counter values of the CPU cores of the corresponding blade. One accumulator circuit is designated as a master, and the other accumulator circuit(s) are designated as slave(s). The slave accumulator circuits transmit their aggregated local counter values to the master accumulator circuit. The master accumulator circuit aggregates the sets of aggregated local counter values to create a set of global counter values. The master accumulator circuit transmits the global counter values to a management processor (for display), to the CPU cores located on its corresponding blade, and to each of the slave accumulator circuits. Each slave accumulator circuit then transmits the global counter values to the CPU cores located on its corresponding blade.
摘要翻译：网络设备包括多个刀片，每个刀片具有处理由网络设备接收的请求的多个CPU内核。每个叶片还包括一个蓄电池电路。每个累加器电路周期性地聚集相应刀片的CPU内核的本地计数器值。一个累加器电路被指定为主机，另一个累加器电路被指定为从机。从累加器电路将其聚合的本地计数器值发送到主累加器电路。主累加器电路聚合本地计数器值集合以创建一组全局计数器值。主累加器电路将全局计数器值发送到管理处理器（用于显示），发送到位于其相应刀片上的CPU核心以及从属累加器电路中的每一个。然后，每个从属累加器电路将全局计数器值发送到位于其相应刀片上的CPU核心。

70. 发明授权

US09079839B2 Methods for preparation of pharmaceutical intermediates of aliskiren 有权
标题翻译：阿利吉仑药物中间体的制备方法
公开(公告)号：US09079839B2
公开(公告)日：2015-07-14
申请号：US13884408
申请日：2011-06-16
申请人： Xuezhi Yin , Bing Wang , Ying Ji , Mingyuan Liu
发明人： Xuezhi Yin , Bing Wang , Ying Ji , Mingyuan Liu
IPC分类号： C07C41/22
CPC分类号： C07C41/22 , C07C43/174 , C07C43/225
摘要： Disclosed are methods for preparation of two pharmaceutical intermediates (I, II) of Aliskiren, said intermediates are obtained by reacting compound of formula I or II and tribromophosphorus oxide. The method replaces the method in the prior art which is using column chromatopraphy to produce the compounds I and II, and overcomes the defect that the method in the prior art hardly carry out in a large-scale industrial production. The product can be purified by recrystallization or vacuum distillation, and the chemical purity of the product is good.
摘要翻译：公开了制备阿利吉仑的两种药物中间体（I，II）的方法，所述中间体通过使式I或II的化合物与三溴磷氧化物反应而获得。该方法代替现有技术中使用柱色谱法生产化合物I和II的方法，克服了现有技术中的方法在大规模工业生产中难以进行的缺点。可以通过重结晶或真空蒸馏纯化产物，产物的化学纯度良好。

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