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61. 发明授权

US11220203B1 Dunnage bag and load strap hanger apparatus and method 有权
公开(公告)号：US11220203B1
公开(公告)日：2022-01-11
申请号：US16412154
申请日：2019-05-14
申请人： John R. Wilson , William M. Wilson
发明人： John R. Wilson , William M. Wilson
IPC分类号： B60P7/08 , B60P7/06 , B60P7/135
摘要： A dunnage bag and load strap hanger apparatus includes a dunnage bag and load strap hanger and a handle mounted applicator block operative to support and affix the dunnage bag and load strap hanger. The dunnage bag and load strap hanger is fabricated from three distinct and separate parts: a generally planar support substrate and two release papers covering adhesive patches or regions on the support substrate. The support substrate in one embodiment is a sheet that is further divided into two contact members separated by a resilient coupler. Each contact member preferably has a contact body, a hanging loop distal to the resilient coupler, and in alternative embodiments an adhesive coating or other fasteners and affixers. In one alternative embodiment there is one affixing surface, and a fastener to couple two contact members together to support a load strap.

62. 发明授权

US09783341B1 Dunnage bag hanger apparatus and method 有权
公开(公告)号：US09783341B1
公开(公告)日：2017-10-10
申请号：US15376130
申请日：2016-12-12
申请人： John R. Wilson , William M. Wilson
发明人： John R. Wilson , William M. Wilson
IPC分类号： B60P7/08 , B65D33/14 , B60P7/06 , B60P7/135
CPC分类号： B65D33/14 , B60P7/065 , B60P7/135
摘要： A dunnage bag hanger apparatus includes a dunnage bag hanger and a handle mounted applicator block operative to support and affix the dunnage bag hanger. The dunnage bag hanger is fabricated from three distinct and separate parts: a generally planar support substrate and two release papers covering adhesive patches or regions on the support substrate. The support substrate in one embodiment is a sheet that is further divided into two contact members separated by a resilient coupler. Each contact member preferably has a contact body, a hanging loop distal to the resilient coupler, and an adhesive coating. The two adhesive couplings are preferably on opposite sides of the support substrate sheet.

63. 发明授权

US09255243B2 Cell culture methods and devices utilizing gas permeable materials 有权
公开(公告)号：US09255243B2
公开(公告)日：2016-02-09
申请号：US10961814
申请日：2004-10-08
申请人： John R. Wilson , Douglas A. Page , Dan Welch , Alison Robeck
发明人： John R. Wilson , Douglas A. Page , Dan Welch , Alison Robeck
IPC分类号： C12M3/00 , C12M1/24 , C12M1/04 , C12M1/12
CPC分类号： C12M23/08 , C12M23/24 , C12M25/06 , C12M25/14 , C12N5/00 , C12N5/0602 , C12N2500/02
摘要： Gas permeable devices and methods are disclosed for cell culture, including cell culture devices and methods that contain medium at heights, and certain gas permeable surface area to medium volume ratios. These devices and methods allow improvements in cell culture efficiency and scale up efficiency.

64. 发明授权

US09193293B2 Dunnage bag hanger apparatus and method 有权
标题翻译：垫料袋衣架装置及方法
公开(公告)号：US09193293B2
公开(公告)日：2015-11-24
申请号：US14534164
申请日：2014-11-05
申请人： John R. Wilson , William M. Wilson
发明人： John R. Wilson , William M. Wilson
IPC分类号： B60P7/08 , B60P7/06 , B60P7/135
CPC分类号： B65D33/14 , B60P7/065 , B60P7/135
摘要： A dunnage bag hanger apparatus includes a dunnage bag hanger and a handle mounted applicator block operative to support and affix the dunnage bag hanger. The dunnage bag hanger is fabricated from three distinct and separate parts: a generally planar support substrate and two release papers covering adhesive patches or regions on the support substrate. The support substrate in one embodiment is a sheet that is further divided into two contact members separated by a resilient coupler. Each contact member preferably has a contact body, a hanging loop distal to the resilient coupler, and an adhesive coating. The two adhesive couplings are preferably on opposite sides of the support substrate sheet.
摘要翻译：垫料袋衣架装置包括衬垫袋悬挂器和手柄安装的施用器块，其可操作以支撑和固定衬垫袋衣架。衬垫袋衣架由三个不同和分开的部件制成：一般为平面的支撑衬底和两个在支撑衬底上覆盖粘合片或区域的剥离纸。一个实施例中的支撑衬底是进一步分为两个由弹性耦合器隔开的接触构件的片材。每个接触构件优选地具有接触体，远离弹性联接器的悬挂环和粘合剂涂层。两个粘合剂联接件优选地在支撑基板的相对侧上。

65. 发明授权

US09182050B2 Piston cap with center vent 有权
标题翻译：活塞帽带中心孔
公开(公告)号：US09182050B2
公开(公告)日：2015-11-10
申请号：US13636284
申请日：2011-03-30
申请人： John R. Wilson
发明人： John R. Wilson
IPC分类号： F16K31/383
CPC分类号： F16K31/3835 , Y10T137/0318
摘要： A flushometer having a cap with a substantially central exhaust passage adapted to remove air from the control chamber. The exhaust passage provides for communication between an upper pressure chamber and an interior piston chamber wherein during a flush cycle a portion of the contents of the upper pressure chamber is evacuated through the exhaust passage into the interior piston chamber and ultimately through the outlet of the flushometer.
摘要翻译：一种具有一个具有大致中心的排气通道的盖的电磁阀，适于从该控制室移除空气。排气通道提供上部压力室和内部活塞室之间的连通，其中在冲洗循环期间，上部压力室的内容物的一部分通过排气通道被排出到内部活塞室中并最终通过火花塞的出口。

66. 发明授权

US09167809B2 Cornea storage container to maximize cornea health 有权
标题翻译：角膜储存容器最大化角膜的健康
公开(公告)号：US09167809B2
公开(公告)日：2015-10-27
申请号：US12817982
申请日：2010-06-17
申请人： Debra Skelnik , Roger Wilson , John R. Wilson
发明人： Debra Skelnik , Roger Wilson , John R. Wilson
IPC分类号： A01N1/02
CPC分类号： A01N1/0273 , A01N1/0263
摘要： An apparatus for shipping, storing, and viewing a cornea comprising a container having a viewing window in a container base, an inner sidewall, and a corneal basket arranged within said container base. The corneal basket is in contact with said inner sidewall and adapted to support a corneoscleral disc by including more than one corneal support rod and more than one disc support surface and a lid that sealingly engages with the container.
摘要翻译：一种用于运输，存储和观察角膜的装置，包括在容器基座中的具有观察窗的容器，内侧壁和布置在所述容器基座内的角膜篮。角膜篮与所述内侧壁接触并且适于通过包括多于一个角膜支撑杆和多于一个盘支撑表面和与容器密封接合的盖来支撑角膜巩膜。

67. 发明授权

US08956860B2 Methods of cell culture for adoptive cell therapy 有权
标题翻译：过继细胞治疗细胞培养方法
公开(公告)号：US08956860B2
公开(公告)日：2015-02-17
申请号：US13475700
申请日：2012-05-18
申请人： Juan F. Vera , Cliona M. Rooney , Ann M. Leen , John R. Wilson
发明人： Juan F. Vera , Cliona M. Rooney , Ann M. Leen , John R. Wilson
IPC分类号： C12M1/12 , C12M1/04 , C12N5/0783
CPC分类号： C12N5/0638 , C12M23/24 , C12N2501/2302 , C12N2502/11
摘要： An improved method of culturing cells for cell therapy applications that includes growing desired cells in the presence of antigen-presenting cells and/or feeder cells and with medium volume to surface area ratio of up to 1 ml/cm2 if the growth surface is not comprised of gas permeable material and up to 2 ml/cm2 if the growth surface is comprised of gas permeable material. The desired cells are at a surface density of less than 0.5×106 cells/cm2 at the onset of a production cycle, and the surface density of the desired cells plus the surface density of the antigen presenting cells and/or feeder cells are at least about 1.25×105 cells/cm2.
摘要翻译：培养用于细胞治疗应用的细胞的改进方法，其包括在存在抗原呈递细胞和/或饲养细胞的情况下生长所需细胞，并且如果不包括生长表面，则中等体积与表面积比高达1ml / cm 2 的气体可渗透材料，如果生长表面由透气材料组成，则高达2ml / cm2。期望的细胞在生产周期开始时的表面密度小于0.5×10 6个细胞/ cm 2，并且所需细胞的表面密度加上抗原呈递细胞和/或饲养细胞的表面密度至少为约1.25×10 5个细胞/ cm 2。

68. 发明授权

US08809050B2 Methods of cell culture for adoptive cell therapy 有权
标题翻译：过继细胞治疗细胞培养方法
公开(公告)号：US08809050B2
公开(公告)日：2014-08-19
申请号：US12963597
申请日：2010-12-08
申请人： Juan F. Vera , Cliona M Rooney , Ann M. Leen , John R. Wilson
发明人： Juan F. Vera , Cliona M Rooney , Ann M. Leen , John R. Wilson
IPC分类号： C12N5/00
CPC分类号： C12N5/0636 , C12N2502/11
摘要： An improved method of culturing cells for cell therapy applications that includes growing desired cells in the presence of antigen-presenting cells and/or feeder cells and with medium volume to surface area ratio of up to 1 ml/cm2 if the growth surface is not comprised of gas permeable material and up to 2 ml/cm2 if the growth surface is comprised of gas permeable material. The desired cells are at a surface density of less than 0.5×106 cells/cm2 at the onset of a production cycle, and the surface density of the desired cells plus the surface density of the antigen presenting cells and/or feeder cells are at least about 1.25×105 cells/cm2.
摘要翻译：培养用于细胞治疗应用的细胞的改进方法，其包括在存在抗原呈递细胞和/或饲养细胞的情况下生长期望的细胞，并且如果不包括生长表面，则中等体积与表面积比高达1ml / cm 2 的气体可渗透材料，如果生长表面由透气材料组成，则高达2ml / cm2。期望的细胞在生产周期开始时的表面密度小于0.5×10 6个细胞/ cm 2，并且所需细胞的表面密度加上抗原呈递细胞和/或饲养细胞的表面密度至少为约1.25×10 5个细胞/ cm 2。

69. 发明授权

US08585008B2 Adjustable flush system 有权
公开(公告)号：US08585008B2
公开(公告)日：2013-11-19
申请号：US12788668
申请日：2010-05-27
申请人： John R. Wilson
发明人： John R. Wilson
IPC分类号： F16K31/12
CPC分类号： F16K31/602 , E03D3/12 , Y10T29/49412 , Y10T137/0491
摘要： A flush valve assembly having a handle assembly positioning bushing for spacing a handle assembly within an opening of the flush valve assembly. The handle assembly positioning bushing having an eccentric opening for receiving the handle such that rotation of the handle assembly positioning bushing with regard to the flush valve assembly body alters the height of the handle assembly and, thus, the volume of water passing through the flush valve assembly during a flush cycle.

70. 发明申请

US20130102075A1 METHODS OF CELL CULTURE FOR ADOPTIVE CELL THERAPY 有权
公开(公告)号：US20130102075A1
公开(公告)日：2013-04-25
申请号：US13475700
申请日：2012-05-18
申请人： Juan F. Vera , Cliona M. Rooney , Ann M. Leen , John R. Wilson
发明人： Juan F. Vera , Cliona M. Rooney , Ann M. Leen , John R. Wilson
IPC分类号： C12M1/04
CPC分类号： C12N5/0638 , C12M23/24 , C12N2501/2302 , C12N2502/11
摘要： An improved method of culturing cells for cell therapy applications that includes growing desired cells in the presence of antigen-presenting cells and/or feeder cells and with medium volume to surface area ratio of up to 1 ml/cm2 if the growth surface is not comprised of gas permeable material and up to 2 ml/cm2 if the growth surface is comprised of gas permeable material. The desired cells are at a surface density of less than 0.5×106 cells/cm2 at the onset of a production cycle, and the surface density of the desired cells plus the surface density of the antigen presenting cells and/or feeder cells are at least about 1.25×105 cells/cm2.

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