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61. 发明申请

US20080191144A1 NON-AXISYMMETRIC CHARGED-PARTICLE BEAM SYSTEM 失效
标题翻译：非轴对称粒子束系统
公开(公告)号：US20080191144A1
公开(公告)日：2008-08-14
申请号：US11968833
申请日：2008-01-03
申请人： Ronak J. Bhatt , Chiping Chen , Jing Zhou
发明人： Ronak J. Bhatt , Chiping Chen , Jing Zhou
IPC分类号： H01J1/50 , H05H7/00
CPC分类号： H01J27/02 , G21K1/093 , H01J3/02 , H01J3/12 , H01J3/20 , H01J29/64
摘要： The charged-particle beam system includes a non-axisymmetric diode forms a non-axisymmetric beam having an elliptic cross-section. A focusing element utilizes a magnetic field for focusing and transporting the non-axisymmetric beam, wherein the non-axisymmetric beam is approximately matched with the channel of the focusing element.
摘要翻译：带电粒子束系统包括非轴对称二极管形成具有椭圆截面的非轴对称束。聚焦元件利用磁场来聚焦和传送非轴对称光束，其中非轴对称光束与聚焦元件的通道近似匹配。

62. 发明申请

US20080173827A1 GENERATION, ACCELERATION, FOCUSING AND COLLECTION OF A HIGH-BRIGHTNESS, SPACE-CHARGE-DOMINATED CIRCULAR CHARGED-PARTICLE BEAM 失效
标题翻译：高亮度，空间充电圆形充电颗粒光束的产生，加速，聚焦和收集
公开(公告)号：US20080173827A1
公开(公告)日：2008-07-24
申请号：US11940495
申请日：2007-11-15
申请人： Chiping Chen , Thomas M. Bemis , Ronak J. Bhatt , Jing Zhou
发明人： Chiping Chen , Thomas M. Bemis , Ronak J. Bhatt , Jing Zhou
IPC分类号： H01J1/50
CPC分类号： G21K5/04 , H01J25/60 , H01J27/00 , H01J37/08 , H01J2237/061 , H01J2237/063 , H01J2237/31701 , H05H15/00
摘要： A high-brightness, space-charge-dominated circular charged-particle beam system includes a flat circular emitter that emits charge particles to form a space-charge-dominated circular charged-particle beam. The space-charge-dominated circular charged-particle beam is emitted from the flat circular emitter with a uniform density and having a current emission being space-charge-limited, obeying the Child-Langmuir law. A diode includes at least one electrode at the flat circular emitter and at least one additional electrode that accelerates the charged particles. A beam tunnel is coupled electrically to at least one of the additional electrodes. An applied axisymmetric magnetic field focuses the space-charge-dominated circular charged-particle beam. A depressed collector collects the space-charge-dominated circular charged-particle beam.
摘要翻译：高亮度，空间电荷主导的圆形带电粒子束系统包括平坦的圆形发射体，其发射电荷粒子以形成空间电荷主导的圆形带电粒子束。空间电荷主导的圆形带电粒子束从平坦的圆形发射器以均匀的密度发射，并且具有限制空间电荷的电流发射，符合Child-Langmuir定律。二极管包括在平坦的圆形发射器处的至少一个电极和加速带电粒子的至少一个附加电极。光束通道电耦合到附加电极中的至少一个。应用轴对称磁场聚焦空间电荷主导的圆形带电粒子束。凹陷式收集器收集以空间电荷为主的圆形带电粒子束。

63. 发明授权

US07381967B2 Non-axisymmetric charged-particle beam system 失效
标题翻译：非轴对称带电粒子束系统
公开(公告)号：US07381967B2
公开(公告)日：2008-06-03
申请号：US11145804
申请日：2005-06-06
申请人： Ronak J. Bhatt , Chiping Chen , Jing Zhou
发明人： Ronak J. Bhatt , Chiping Chen , Jing Zhou
IPC分类号： B01D59/44 , H01J49/00
CPC分类号： H01J27/02 , G21K1/093 , H01J3/02 , H01J3/12 , H01J3/20 , H01J29/64
摘要： The charged-particle beam system includes a non-axisymmetric diode forms a non-axisymmetric beam having an elliptic cross-section. A focusing element utilizes a magnetic field for focusing and transporting the non-axisymmetric beam, wherein the non-axisymmetric beam is approximately matched with the channel of the focusing element.
摘要翻译：带电粒子束系统包括非轴对称二极管形成具有椭圆截面的非轴对称束。聚焦元件利用磁场来聚焦和传送非轴对称光束，其中非轴对称光束与聚焦元件的通道近似匹配。

64. 发明申请

US20080071590A1 Solving a model to select members of a portfolio 审中-公开
标题翻译：解决模型来选择投资组合的成员
公开(公告)号：US20080071590A1
公开(公告)日：2008-03-20
申请号：US11521621
申请日：2006-09-15
申请人： Bin Zhang , Dirk M. Beyer , Shailendra Jain , Jing Zhou
发明人： Bin Zhang , Dirk M. Beyer , Shailendra Jain , Jing Zhou
IPC分类号： G06F9/44
CPC分类号： G06Q40/06 , G06F17/11 , G06Q10/0637 , G06Q10/06375 , G06Q40/04
摘要： A computer-executable method provides plural constraints representing corresponding objectives of an enterprise, where the objectives are related to members of the enterprise's portfolio. A model is provided for selecting the members of the portfolio, where the model contains the plural constraints. The model is solved to select the members of the portfolio.
摘要翻译：计算机可执行方法提供表示企业的相应目标的多个约束，其目标与企业投资组合的成员有关。提供了一个模型来选择投资组合的成员，其中模型包含多个约束。该模型被解决以选择投资组合的成员。

65. 发明申请

US20060290452A1 Non-axisymmetric periodic permanent magnet focusing system 失效
标题翻译：非轴对称周期永磁聚焦系统
公开(公告)号：US20060290452A1
公开(公告)日：2006-12-28
申请号：US11434835
申请日：2006-05-15
申请人： Ronak Bhatt , Chiping Chen , Jing Zhou , Alexey Radovinsky
发明人： Ronak Bhatt , Chiping Chen , Jing Zhou , Alexey Radovinsky
IPC分类号： H01F7/00
CPC分类号： H01F7/0278 , H01J23/087 , H01J23/0873 , H05H7/04
摘要： A permanent magnet focusing system includes an electron gun that provides an electron ribbon beam having an elliptical shape. A plurality of permanent magnets provide transport for the electron ribbon beam. The permanent magnets produce a non-axisymmetric periodic permanent magnet (PPM) focusing field to allow the electron ribbon beam to be transported in the permanent magnet focusing system.
摘要翻译：永磁体聚焦系统包括提供具有椭圆形状的电子束束的电子枪。多个永磁体提供电子束束的输送。永磁体产生非轴对称周期永磁体（PPM）聚焦场，以允许电子束束在永磁体聚焦系统中传输。

66. 发明申请

US20050233014A1 Methods for affecting homeostasis and metabolism in a mammalian body 审中-公开
标题翻译：影响哺乳动物体内的体内平衡和代谢的方法
公开(公告)号：US20050233014A1
公开(公告)日：2005-10-20
申请号：US11069836
申请日：2005-03-01
申请人： Steve Lee , Richard Hynson , Ke-Qin Zhang , Wu-Zhou Li , Jing Zhou
发明人： Steve Lee , Richard Hynson , Ke-Qin Zhang , Wu-Zhou Li , Jing Zhou
IPC分类号： A61K31/198 , A61K36/48 , A61K35/78
CPC分类号： A61K31/198 , A61K36/48 , A61K2300/00
摘要： The present invention is directed to novel compositions of bio-active compounds comprising 4-hydroxyisoleucine and one or more compounds selected from the group of amino acids, alkaloids, glycosides, volatile oils, saponins, sapogenins, mannans, flavonoids, fatty acids, vitamins and provitamins, minerals, and carbohydrates. Preferably, the novel compositions of bio-active compounds include 4-hydroxyisoleucine and one or more amino acids selected from the group consisting of arginine, aspartate, threonine, serine, glutamate, proline, glycine, alanine, cysteine, valine, methionine, isoleucine, leucine, tryptophan, phenylalanine, ornithine, proline, lysine, histidine, and gamma-aminobutyrate. The composition of bio-active compounds preferably include between about ten percent and about seventy percent of 4-hydroxyisoleucine and between about twenty percent and about forty percent of other amino acids. The bio-active compounds of the novel composition of the present invention may be derived, isolated, and/or extracted from Fenugreek seeds. A preferred method for extracting the bio-active compounds from Fenugreek seeds includes the steps of: (1) providing a plurality of Fenugreek seeds; (2) preparing the Fenugreek seeds; and (3) extracting a novel composition of bio-active compounds from the Fenugreek seeds, which include a preliminary extraction step and a secondary extraction step. The compositions of bio-active compounds have been found to be helpful in restoring healthy energy balance in humans and animals, aiding in weight management efforts, and for balancing blood sugar levels by way of assisting the body to make more efficient use of existing (i.e., endogenous) insulin.
摘要翻译：本发明涉及包含4-羟基异亮氨酸和一种或多种选自氨基酸，生物碱，糖苷，挥发性油，皂角苷，皂甙元，甘露聚糖，类黄酮，脂肪酸，维生素和/或其中的一种或多种化合物的生物活性化合物的新组合物，维生素，矿物质和碳水化合物。优选地，生物活性化合物的新组合物包括4-羟基异亮氨酸和一种或多种选自精氨酸，天冬氨酸，苏氨酸，丝氨酸，谷氨酸，脯氨酸，甘氨酸，丙氨酸，半胱氨酸，缬氨酸，甲硫氨酸，异亮氨酸，亮氨酸，色氨酸，苯丙氨酸，鸟氨酸，脯氨酸，赖氨酸，组氨酸和γ-氨基丁酸。生物活性化合物的组成优选包括约10％至约70％的4-羟基异亮氨酸和约20％至约40％的其它氨基酸。本发明的新型组合物的生物活性化合物可以从胡芦巴种子中衍生，分离和/或提取。从葫芦巴种子提取生物活性化合物的优选方法包括以下步骤：（1）提供多种葫芦巴种子; （2）准备葫芦巴种子; （3）从葫芦巴种子中提取生物活性化合物的新组合物，其中包括初步提取步骤和二次提取步骤。已经发现生物活性化合物的组合有助于恢复人和动物中的健康能量平衡，帮助体重管理工作，以及通过协助身体更有效地利用现有的（例如，，内源性）胰岛素。

67. 发明申请

US20050226948A1 Methods for enhancing the transport of glucose into muscle 审中-公开
标题翻译：增强葡萄糖输送到肌肉中的方法
公开(公告)号：US20050226948A1
公开(公告)日：2005-10-13
申请号：US11068733
申请日：2005-03-01
申请人： Steve Lee , Richard Hynson , Ke-Qin Zhang , Wu-Zhou Li , Jing Zhou
发明人： Steve Lee , Richard Hynson , Ke-Qin Zhang , Wu-Zhou Li , Jing Zhou
IPC分类号： A61K31/198 , A61K31/401 , A61K31/4745 , A61K36/48 , A61K35/78
CPC分类号： A61K31/4745 , A61K31/198 , A61K31/401 , A61K36/48 , A61K2300/00
摘要： The present invention is directed to novel compositions of bio-active compounds comprising 4-hydroxyisoleucine and one or more compounds selected from the group of amino acids, alkaloids, glycosides, volatile oils, saponins, sapogenins, mannans, flavonoids, fatty acids, vitamins and provitamins, minerals, and carbohydrates. Preferably, the novel compositions of bio-active compounds include 4-hydroxyisoleucine and one or more amino acids selected from the group consisting of arginine, aspartate, threonine, serine, glutamate, proline, glycine, alanine, cysteine, valine, methionine, isoleucine, leucine, tryptophan, phenylalanine, ornithine, proline, lysine, histidine, and gamma-aminobutyrate. The composition of bio-active compounds preferably include between about ten percent and about seventy percent of 4-hydroxyisoleucine and between about twenty percent and about forty percent of other amino acids. The bio-active compounds of the novel composition of the present invention may be derived, isolated, and/or extracted from Fenugreek seeds. A preferred method for extracting the bio-active compounds from Fenugreek seeds includes the steps of: (1) providing a plurality of Fenugreek seeds; (2) preparing the Fenugreek seeds; and (3) extracting a novel composition of bio-active compounds from the Fenugreek seeds, which include a preliminary extraction step and a secondary extraction step. The compositions of bio-active compounds have been found to be helpful in restoring healthy energy balance in humans and animals, aiding in weight management efforts, and for balancing blood sugar levels by way of assisting the body to make more efficient use of existing (i.e., endogenous) insulin.
摘要翻译：本发明涉及包含4-羟基异亮氨酸和一种或多种选自氨基酸，生物碱，糖苷，挥发性油，皂角苷，皂甙元，甘露聚糖，类黄酮，脂肪酸，维生素和/或其中的一种或多种化合物的生物活性化合物的新组合物，维生素，矿物质和碳水化合物。优选地，生物活性化合物的新组合物包括4-羟基异亮氨酸和一种或多种选自精氨酸，天冬氨酸，苏氨酸，丝氨酸，谷氨酸，脯氨酸，甘氨酸，丙氨酸，半胱氨酸，缬氨酸，甲硫氨酸，异亮氨酸，亮氨酸，色氨酸，苯丙氨酸，鸟氨酸，脯氨酸，赖氨酸，组氨酸和γ-氨基丁酸。生物活性化合物的组合物优选包括约10％至约70％的4-羟基异亮氨酸和约20％至约40％的其它氨基酸。本发明的新型组合物的生物活性化合物可以从胡芦巴种子中衍生，分离和/或提取。从葫芦巴种子提取生物活性化合物的优选方法包括以下步骤：（1）提供多种葫芦巴种子; （2）准备葫芦巴种子; （3）从葫芦巴种子中提取生物活性化合物的新组合物，其中包括初步提取步骤和二次提取步骤。已经发现生物活性化合物的组合有助于恢复人和动物中的健康能量平衡，帮助体重管理工作，以及通过协助身体更有效地利用现有的（例如，，内源性）胰岛素。

68. 发明授权

US09637797B2 Methods and nucleotide fragments of predicting occurrence, metastasis of cancers and patients' postoperative survival in vitro 有权
公开(公告)号：US09637797B2
公开(公告)日：2017-05-02
申请号：US14378285
申请日：2012-02-13
申请人： Dajun Deng , Jun Zhang , Zhaojun Liu , Jing Zhou , Liankun Gu , Baozhen Zhang
发明人： Dajun Deng , Jun Zhang , Zhaojun Liu , Jing Zhou , Liankun Gu , Baozhen Zhang
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/02 , C07H21/04 , G06F19/22
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/154 , C12Q2600/158 , G06F19/22
摘要： Provided in the present invention are a method using in vitro measurement of the content of methylation or demethylation of GFRa1 CpG islands to estimate a risk of tumorigenesis and of tumor metastasis, or postoperative life expectancy, and a nucleotide sequence used.

69. 发明申请

US20170085688A1 Flexible Computing Devices 审中-公开
公开(公告)号：US20170085688A1
公开(公告)日：2017-03-23
申请号：US15338040
申请日：2016-10-28
申请人： Jing Zhou , Melora Zaner , Shannon You
发明人： Jing Zhou , Melora Zaner , Shannon You
IPC分类号： H04M1/02 , H04B5/00 , H04B1/3816 , G06F3/01 , H04B11/00 , G09G3/14 , G06F1/16 , H04W4/00 , H04B1/3818
CPC分类号： H04M1/0268 , G06F1/163 , G06F1/1694 , G06F1/1698 , G06F3/011 , G09G3/14 , G09G2370/16 , G09G2380/02 , G09G2380/06 , H04B1/3816 , H04B1/385 , H04B5/0062 , H04B2001/3861 , H04M1/0264 , H04M2250/02 , H04M2250/04 , H04M2250/10 , H04M2250/12 , H04W4/80
摘要： A device includes a housing adapted for wearing on a human body, with a sparse light-emitting array including a plurality of spaced light-emitting sources, a control circuit including a wireless module, the control circuit configured to control lighting of the sparse light-emitting array in response to external control signals that are received wirelessly; and at least one electrical contact arranged on the housing, the at least one electrical contact arranged to provide at least one of: electrical power to the smart wearable device or data transfer between the smart wearable device and an external device.

70. 发明授权

US09381154B2 Direct inkjet fabrication of drug delivery devices 有权
标题翻译：药物输送装置的直接喷墨制造
公开(公告)号：US09381154B2
公开(公告)日：2016-07-05
申请号：US13156503
申请日：2011-06-09
申请人： Jing Zhou , Shu Chang
发明人： Jing Zhou , Shu Chang
IPC分类号： A61K9/20 , C09D11/34 , A61K9/00 , A61K9/24
CPC分类号： A61K9/0056 , A61K9/209 , A61K9/2095 , B33Y30/00 , B33Y80/00
摘要： In some aspects of the present application, a method of forming one or more layers of at least a portion of a drug delivery device (DDD) is described. The method can include providing a substrate; providing one or more DDD components that are dissolved or dispersed in one or more pharmaceutically compatible phase change inks; ejecting, by one or more nozzles, a first portion of the one or more pharmaceutically compatible phase change inks to form a first layer on the substrate; and ejecting, by the one or more nozzles, a second portion of the pharmaceutically compatible phase change inks to form a second layer over the first layer.
摘要翻译：在本申请的一些方面，描述了形成药物递送装置（DDD）的至少一部分的一个或多个层的方法。该方法可以包括提供基底; 提供溶解或分散在一种或多种药学上相容的相变油墨中的一种或多种DDD组分; 通过一个或多个喷嘴喷射所述一种或多种药学上相容的相变油墨的第一部分以在所述基底上形成第一层; 以及通过所述一个或多个喷嘴喷射所述药学上相容的相变油墨的第二部分，以在所述第一层上形成第二层。

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