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61. 发明授权

US06426365B1 CETP activity inhibitors 有权
标题翻译： CETP活性抑制剂
公开(公告)号：US06426365B1
公开(公告)日：2002-07-30
申请号：US09367299
申请日：1999-12-23
申请人： Hisashi Shinkai , Kimiya Maeda , Hiroshi Okamoto
发明人： Hisashi Shinkai , Kimiya Maeda , Hiroshi Okamoto
IPC分类号： A61K31165
CPC分类号： C07D307/10 , A61K31/164 , A61K31/18 , A61K31/33 , A61K31/341 , A61K31/381 , A61K31/40 , A61K31/435 , A61K31/44 , C07C311/14 , C07C311/15 , C07C311/21 , C07C323/40 , C07C323/41 , C07C323/42 , C07C327/30 , C07C329/10 , C07C329/20 , C07C333/04 , C07C333/08 , C07C333/10 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2602/22 , C07C2602/28 , C07C2603/74 , C07D211/34 , C07D213/80 , C07D213/81 , C07D307/68 , C07D333/38 , Y02P20/55
摘要： The present invention provides a CETP activity inhibitor comprising as an active ingredient a compound represented by the formula (I): wherein R represents a straight chain or branched alkyl group; a straight chain or branched alkenyl group; a lower haloalkyl group; a substituted or unsubstituted cycloalkyl group; a substituted or unsubstituted cycloalkenyl group; a substituted or unsubstituted cycloalkylalkyl group; a substituted or unsubstituted aryl group, or a substituted or unsubstituted heterocyclic group, X1, X2, X3, and X4 may be the same or different and each represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower haloalkyl group; a lower alkoxy group; a cyano group; a nitro group; an acyl group; or an aryl group, Y represents —CO— or —SO2—, and Z represents a hydrogen atom or a mercapto-protecting group, or a prodrug compound, a pharmaceutically acceptable salt, or hydrate or solvate thereof. The compounds represented by the formula (I) can increase HDL and at the same time decrease LDL through selective inhibition of CETP activity and, therefore, is expected to be useful as a new type of a preventive or therapeutic agent for atherosclerosis or hyperlipidemia.
摘要翻译：本发明提供一种CETP活性抑制剂，其包含由式（I）表示的化合物作为活性成分：其中R表示直链或支链烷基; 直链或支链烯基; 低级卤代烷基; 取代或未取代的环烷基; 取代或未取代的环烯基; 取代或未取代的环烷基烷基; 取代或未取代的芳基或取代或未取代的杂环基，X 1，X 2，X 3和X 4可以相同或不同，各自表示氢原子，卤素原子，低级烷基，低级卤代烷基。低级烷氧基; 氰基; 硝基; 酰基; 或芳基，Y表示-CO-或-SO 2 - ，Z表示氢原子或巯基保护基，或前药化合物，其药学上可接受的盐或水合物或溶剂化物。由式（I）表示的化合物可以增加HDL，同时通过选择性抑制CETP活性降低LDL，因此预期可用作动脉粥样硬化或高脂血症的新型预防或治疗剂。

62. 发明授权

US06420026B1 Composite filament, process for the production of the same, and heat fused article 失效
标题翻译：复合长丝，生产过程和热熔制品
公开(公告)号：US06420026B1
公开(公告)日：2002-07-16
申请号：US09663708
申请日：2000-09-18
申请人： Hiroshi Okamoto , Shin-ichi Inoue , Tetsuo Kanagawa , Masataka Sano , Hiroki Miyamatsu , Kimi Yoshida , Nobuo Goto , Akira Yamanaka , Tomio Yamazawa , Takahiro Sugimoto
发明人： Hiroshi Okamoto , Shin-ichi Inoue , Tetsuo Kanagawa , Masataka Sano , Hiroki Miyamatsu , Kimi Yoshida , Nobuo Goto , Akira Yamanaka , Tomio Yamazawa , Takahiro Sugimoto
IPC分类号： D01F800
CPC分类号： D01F8/06 , D01F1/10 , Y10T428/2924
摘要： The invention is aimed to provide a core-sheath type composite filament, in which a functional component is hardly lost due to volatilization during the melt forming; bleeding of the internally added functional component is effectively inhibited; the internally added functional component does not adversely affect spinning properties, stretching properties, strength and dimensional stability; the use of the functional component can be greatly reduced, leading to a reduction of production cost; superior functionalities of deodorizing properties and antimicrobial properties can be exhibited to a maximum extent; even when contacting with water, the functionalities can be kept over a long time; and the composite filament is highly safe to a human body. The invention is also aimed to provide a process for the production of the core-sheath type composite filament as well as a heat fused article obtained from the composite filament. The core-sheath type composite filament of the invention is composed of a core component X and a sheath component Y, wherein the core component X is formed from a first polyolefin resin (H), and the sheath component Y is formed from a second polyolefin resin (L) compounded with at least one functional component (A) selected from the group consisting of a catechin, a saponin, a tea-leaf powder, a tea-leaf extract, and tannin (tannic acid), and a ceramics component (C).
摘要翻译：本发明的目的在于提供一种芯鞘型复合长丝，其中功能性成分在熔融成形期间由于挥发而几乎不会损失; 内部添加的功能成分的渗透被有效地抑制; 内部添加的功能组分不会对纺丝性能，拉伸性能，强度和尺寸稳定性产生不利影响; 功能部件的使用可以大大降低，导致生产成本降低; 除臭性能和抗菌性能优异的功能最大程度可以展现出来; 即使与水接触，功能也可以长时间保持; 复合长丝对人体的安全性高。本发明的目的还在于提供一种用于生产芯鞘型复合长丝的方法以及由复合长丝获得的热熔制品。本发明的芯鞘型复合长丝由芯成分X和鞘成分Y构成，其中，芯成分X由第一聚烯烃树脂（H）形成，鞘成分Y由第二聚烯烃与选自由儿茶素，皂角苷，茶叶粉末，茶叶提取物和单宁酸（鞣酸）组成的组中的至少一种功能性成分（A）和陶瓷成分（ C）。

63. 发明授权

US5838301A Still picture reproduction system that allows skip 失效
标题翻译：允许跳过检索的静态图像再现系统
公开(公告)号：US5838301A
公开(公告)日：1998-11-17
申请号：US741034
申请日：1996-10-30
申请人： Hiroshi Okamoto , Youji Sugiura
发明人： Hiroshi Okamoto , Youji Sugiura
IPC分类号： H04N5/91 , H04N1/00 , H04N1/21 , H04N5/76 , H04N5/781 , H04N5/783 , H04N5/85 , H04N5/93 , H04N5/937
CPC分类号： H04N1/00458 , H04N1/00198 , H04N1/0044 , H04N1/00461 , H04N1/2166 , H04N5/937 , H04N5/781 , H04N5/783 , H04N5/85
摘要： In a still picture reproduction system used for presentation of pictures in museums, a particular still picture can be retrieved rapidly by applying a retroactive reproduction function. When the mode is switched from a normal reproduction mode to a retroactive reproduction mode by a mouse, only the first still picture of a series of still pictures reproduced in the normal reproduction mode is reproduced and displayed on an HDTV. These first still pictures in each of a number of series are selectively and manually switched in sequence.
摘要翻译：在用于在博物馆中呈现图片的静止图像再现系统中，可以通过应用追溯再现功能来快速检索特定静止图像。当通过鼠标将模式从正常再现模式切换到追溯再现模式时，只有在正常再现模式中再现的一系列静止图像的第一静止图像被再现并显示在HDTV上。这些序列中的每一个中的这些第一静止图像依次选择性地和手动地切换。

64. 发明授权

US5401278A Method of making battery plates for lead acid storage batteries 失效
标题翻译：铅酸蓄电池电池板的制作方法
公开(公告)号：US5401278A
公开(公告)日：1995-03-28
申请号：US42513
申请日：1993-04-05
申请人： Hiroshi Yasuda , Kazuyoshi Yonezu , Hiroshi Okamoto , Katsuhiro Takahashi
发明人： Hiroshi Yasuda , Kazuyoshi Yonezu , Hiroshi Okamoto , Katsuhiro Takahashi
IPC分类号： H01M4/20 , H01M4/68 , H01M4/74 , H01M4/82
CPC分类号： H01M4/745 , H01M4/20 , Y02P70/54 , Y10T29/10
摘要： A battery plate for lead acid storage batteries using a grid prepared by expanding a lead-calcium-tin (Pb--Ca--Sn) alloy sheet, is made by expanding a Pb--Ca--Sn alloy sheet having a tensile strength of 6.0 kg/mm.sup.2 or lower and an Sn content of 0.6-1.8% by weight to make a grid,filling this grid with an active material paste, and then aging the grid to increase the tensile strength of the expanded grid to 7.0 kg/mm.sup.2 or higher. The workability in expanding of the Pb--Ca--Sn alloy sheet can be improved and furthermore, concentration of stress strain on the nodes of the grid can be inhibited and thus, corrosion of the nodes can be inhibited. The aging can provide a battery pate having a high tensile strength and a lead acid storage battery having an excellent charge-discharge cycle life characteristics.
摘要翻译：使用通过膨胀铅 - 钙 - 锡（Pb-Ca-Sn）合金板制备的网格的铅酸蓄电池的电池板是通过将拉伸强度为6.0kg / cm 2的Pb-Ca-Sn合金板， mm2以下，Sn含量为0.6〜1.8重量％，制成格栅，用活性材料浆料填充该格栅，然后使网格老化，将扩展网格的拉伸强度提高至7.0kg / mm2以上。可以提高Pb-Ca-Sn合金板的膨胀的可加工性，并且可以抑制电网节点上的应力应变集中，从而可以抑制节点的腐蚀。老化可以提供具有高拉伸强度的电池头和具有优异的充放电循环寿命特性的铅酸蓄电池。

65. 发明授权

US5327445A Quantum-well type semiconductor laser device 失效
标题翻译：量子阱型半导体激光器件
公开(公告)号：US5327445A
公开(公告)日：1994-07-05
申请号：US854646
申请日：1992-07-09
申请人： Narihito Matsumoto , Akihiko Kasukawa , Takeshi Namegaya , Hiroshi Okamoto
发明人： Narihito Matsumoto , Akihiko Kasukawa , Takeshi Namegaya , Hiroshi Okamoto
IPC分类号： H01S5/34 , H01S5/343 , H01S3/19
CPC分类号： H01S5/3434 , B82Y20/00 , H01S5/34 , H01S2301/18 , H01S5/3421 , H01S5/34306
摘要： In a quantum-well type semiconductor laser device comprising a multi-layered quantum-well layer (active layer) constituted by quantum-well layers and a corresponding number of barrier layers and a pair of optical confinement layers respectively arranged on and under the active layer, since the number of quantum-well layers is limited to one or two, the device has a reduced internal loss, a narrowed far-field angle and a bandgap energy of the quantum-well layers greater than that of the optical confinement layers by more than 160 meV so that it shows a lowered threshold current density. Besides, by selecting a thickness of the quantum-well layers between 3 and 8 nm, the device can be made to oscillate at the first quantum level in order to make the oscillation wavelength highly dependent on temperature and optical output and accordingly produce a high spectral purity.
摘要翻译： PCT No.PCT / JP91 / 01213 Sec。 371日期：1992年7月9日 102（e）日期1992年7月9日PCT 1991年9月12日PCT PCT。公开号WO92 / 04753 日期：1992年3月19日。在包括由量子阱层和相应数量的势垒层和一对光限制层构成的多层量子阱层（有源层）的量子阱型半导体激光器件中，布置在有源层上和下面，由于量子阱层的数量被限制为一个或两个，器件具有减小的内部损耗，窄的远场角和量子阱层的带隙能量大于的光限制层超过160meV，使得其显示出降低的阈值电流密度。此外，通过选择3和8nm之间的量子阱层的厚度，可以使器件在第一量子电平处振荡，以使振荡波长高度依赖于温度和光输出，从而产生高光谱纯度。

66. 发明授权

US5173447A Method for producing strained quantum well semiconductor laser elements 失效
标题翻译：应变量子阱半导体激光元件的制造方法
公开(公告)号：US5173447A
公开(公告)日：1992-12-22
申请号：US777910
申请日：1991-10-17
申请人： Teturo Ijichi , Hiroshi Okamoto
发明人： Teturo Ijichi , Hiroshi Okamoto
IPC分类号： H01S5/20 , H01S5/223 , H01S5/32 , H01S5/34 , H01S5/343
CPC分类号： B82Y20/00 , H01S5/32 , H01S5/34313 , H01S5/209 , H01S5/223 , H01S5/2231 , H01S5/3406
摘要： A semiconductor laser element having a GaAs substrate formed thereon with an active layer of a strained quantum well construction provided with an In.sub.x Ga.sub.1-x As strained quantum well layer and a GaAs barrier layer, and clad layers arranged up and down said active layer through an epitaxial growth means. The lattice mismatching rate of the clad layer with respect to the substrate is less than 10.sup.-3.
摘要翻译：一种半导体激光元件，其具有在其上形成有具有In x Ga 1-x As应变量子阱层和GaAs势垒层的应变量子阱结构的有源层的GaAs衬底，以及通过外延生长向上和向下布置所述有源层的覆层手段。包覆层相对于衬底的晶格失配率小于10-3。

67. 发明授权

US5159388A Image forming apparatus 失效
标题翻译：图像形成装置
公开(公告)号：US5159388A
公开(公告)日：1992-10-27
申请号：US720938
申请日：1991-06-25
申请人： Tsugihito Yoshiyama , Hiroshi Okamoto , Moriyoshi Matsushiro , Masataka Oda , Masayasu Haga
发明人： Tsugihito Yoshiyama , Hiroshi Okamoto , Moriyoshi Matsushiro , Masataka Oda , Masayasu Haga
IPC分类号： G03G15/02 , G03G15/00 , G03G15/043 , G03G15/06 , G03G21/00
CPC分类号： G03G15/75 , G03G15/043 , G03G15/065
摘要： An image forming apparatus comprising a charging section for uniformly charging a surface of a photoconductive body; an image forming section for forming an image on the photoconductive body charged by the charging section; a detecting section for detecting an influx current flowing to the photoconductive body when the photoconductive body is charged by the charging section; and a control section for controlling the image forming section so as to stabilize a quality of images formed by the image forming section.
摘要翻译：一种图像形成装置，包括用于对光电导体的表面均匀充电的充电部分; 图像形成部，用于在由充电部充电的感光体上形成图像; 检测部，其检测当所述光电导体被所述充电部充电时流向所述光电导体的流入电流; 以及控制部分，用于控制图像形成部分，以便稳定由图像形成部分形成的图像的质量。

68. 发明授权

US5122834A Developing apparatus for determining decreased concentration of toner 失效
标题翻译：用于确定调色剂浓度降低的显影装置
公开(公告)号：US5122834A
公开(公告)日：1992-06-16
申请号：US578255
申请日：1990-09-06
申请人： Hiroshi Okamoto , Chujiro Yokoyama , Moriyoshi Matsushiro , Yasuhiro Kusuda
发明人： Hiroshi Okamoto , Chujiro Yokoyama , Moriyoshi Matsushiro , Yasuhiro Kusuda
IPC分类号： G03G15/08
CPC分类号： G03G15/0822 , G03G15/0849 , G03G15/0853 , G03G15/0893 , G03G2215/0822
摘要： A developing apparatus comprising: a developing device for contacting an electrostatic image-bearing member with a development mix of toner and carrier particles; a first transporting member for transporting the mix to the developing device, a second transporting member for transporting the mix to the first transporting member; a third transporting member for transporting the mix to the second transporting member such that first and second circulations of the mix are, respectively, formed between the first and second transporting members and between the second and third transporting members; a sensor for producing a concentration signal having a value indicative of the ratio of toner in the mix of the first circulation, which is disposed in the first circulation of the mix; and a toner replenishing device for replenishing toner to the second circulation of the mix in response to the concentration signal such that the toner is replenished from an area except for the area corresponding to the second transporting member in the second circulation of the mix.
摘要翻译：一种显影装置，包括：用于使静电图像承载部件与调色剂和载体颗粒的显影混合物接触的显影装置; 用于将混合物输送到显影装置的第一输送构件，用于将混合物输送到第一输送构件的第二输送构件; 第三输送构件，用于将混合物输送到第二输送构件，使得混合物的第一和第二循环分别形成在第一和第二输送构件之间以及第二和第三输送构件之间; 用于产生浓度信号的传感器，其具有指示混合物的第一循环中的第一循环的混合物中的调色剂的比率的值; 以及调色剂补充装置，用于响应于浓度信号将调色剂补充到混合物的第二循环，使得调色剂从混合物的第二循环中对应于第二输送构件的区域以外的区域补充。

69. 发明授权

US5104240A Release bearing assembly 失效
标题翻译：释放轴承组件
公开(公告)号：US5104240A
公开(公告)日：1992-04-14
申请号：US675520
申请日：1991-03-27
申请人： Hiroshi Okamoto , Yukihisa Takashi , Masaru Ebata
发明人： Hiroshi Okamoto , Yukihisa Takashi , Masaru Ebata
IPC分类号： F16D23/14
CPC分类号： F16D23/146
摘要： There is disclosed an improved release bearing assembly that is component of the pull-type clutch cover of a friction clutch mounted in an automobile. The release bearing assembly comprises a bearing body capable of moving axially within a given range, a retainer ring holding a diaphragm spring, a sleeve disposed between the bearing body and the ring, several resilient sheets extending from the flange of the sleeve axially of the sleeve, fingers formed at the front ends of the resilient sheets, and a release groove formed in the outer surface of the sleeve. The resilient sheets are circumferentially spaced from each other. The sleeve can slide on the bearing body between a first position and a second position. In the first position that is close to the retainer ring, the sleeve clamps the ring against the bearing body via the fingers. In the second position, the resilient sheets can play within a release groove formed in the bearing body, so that the ring disengages from the bearing body.
摘要翻译：公开了一种改进的释放轴承组件，其是安装在汽车中的摩擦离合器的拉式离合器盖的部件。释放轴承组件包括能够在给定范围内轴向运动的轴承体，保持膜片弹簧的保持环，设置在轴承体和环之间的套筒，从套筒的凸缘轴向延伸的若干弹性片形成在弹性片的前端的指状物和形成在套筒的外表面中的释放槽。弹性片彼此周向间隔开。套筒可以在第一位置和第二位置之间在轴承体上滑动。在靠近止动环的第一位置，套筒通过手指将环卡紧在轴承体上。在第二位置，弹性片可以在形成于轴承体中的释放槽内游动，使得环从轴承体脱离。

70. 发明授权

US5032936A Tape tension apparatus 失效
标题翻译：胶带张力装置
公开(公告)号：US5032936A
公开(公告)日：1991-07-16
申请号：US370879
申请日：1989-06-23
申请人： Souichirou Fujioka , Hiroshi Okamoto
发明人： Souichirou Fujioka , Hiroshi Okamoto
IPC分类号： G11B15/43 , G11B15/467
CPC分类号： G11B15/467 , G11B15/43
摘要： A tape traveling apparatus drives differentially a tracking control actuator and a tension control actuator by inputting simultaneously into a tension controller a tracking instruction signal inputted into a tracking controller, and variably adjusts an amplification of the tracking instruction signal inputted into the tension controller according to an output of a tension sensor for detecting a tension variation of a tape, thereby eliminating a differential error between the tracking control actuator and the tension control actuator.
摘要翻译：磁带传送装置通过同时向张力控制器输入输入到跟踪控制器中的跟踪指令信号来驱动跟踪控制致动器和张力控制致动器，并根据输入到张力控制器的跟踪指令信号的放大可变地调节输出用于检测带的张力变化的张力传感器，从而消除跟踪控制致动器和张力控制致动器之间的差分误差。

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