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51. 发明授权

US3954808A Methylene bis-phenol alkanoic acid compounds 失效
标题翻译：亚甲基双酚链烷酸化合物
公开(公告)号：US3954808A
公开(公告)日：1976-05-04
申请号：US412027
申请日：1973-11-01
申请人： John Scotchford Elliott , Bryan Terence Davis , Richard Martin Howlett
发明人： John Scotchford Elliott , Bryan Terence Davis , Richard Martin Howlett
IPC分类号： C10M129/76 , B01F17/40 , C07C59/52 , C07C65/00 , C07C69/76 , C07C69/88 , C07D307/78 , C07D307/88 , C07D311/20 , C07D313/08 , C08G8/02 , C08G8/04 , C10L1/18 , C10M129/44 , C10M169/00 , C10N30/04 , C10N40/25 , C07C63/52 , C07D311/02
CPC分类号： C07C323/00 , C07C59/52 , C07D307/88 , C07D311/20 , C07D313/08 , C10M1/08 , C10M2207/044 , C10M2207/121 , C10M2207/122 , C10M2207/123 , C10M2207/124 , C10M2207/129 , C10M2207/22 , C10M2207/281 , C10M2207/282 , C10M2207/283 , C10M2207/286 , C10M2209/00 , C10M2209/02 , C10M2209/10 , C10M2219/082 , C10M2219/087 , C10M2219/088 , C10M2219/089 , C10M2221/02
摘要： Novel compounds, useful as intermediates in the preparation of lubricant additives, are described by specified general formulae and as condensation products of (i) an alkyl-substituted monohydric phenol, phenol sulphide or alkylene bis-phenol in which the alkyl substituent contains at least 8 carbon atoms and (ii) a carbonyl-substituted compound selected from the group consisting of glyoxylic acid, pyruvic acid, levulinic acid, 3-oxoglutaric acid, 2-oxoglutaric acid and esters of such acids.
摘要翻译：用作制备润滑剂添加剂的中间体的新型化合物由具体通式描述，并且作为（i）烷基取代的一元酚，苯酚硫化物或亚烷基双酚的缩合产物，其中烷基取代基含有至少8个碳原子和（ii）选自乙醛酸，丙酮酸，乙酰丙酸，3-氧戊二酸，2-氧戊二酸和这些酸的酯的羰基取代的化合物。

52. 发明授权

US3862220A Method of preparing halogenated olefinic derivatives of saturated gamma-keto mono-carboxy acids and related compounds 失效
标题翻译：制备饱和甘氨酸 - 酮酸单羧酸和相关化合物的低聚烯醇衍生物的方法
公开(公告)号：US3862220A
公开(公告)日：1975-01-21
申请号：US28481572
申请日：1972-08-30
申请人： AIR PROD & CHEM
发明人： ERBY WILLIAM A , WALDE ROBERT A
IPC分类号： C07C59/88 , C07D307/58 , C07C65/00
CPC分类号： C07C59/88 , C07D307/58
摘要： Direct halogenation of C4-C10 saturated keto monocarboxy acids or their acidogenic derivatives with elemental halogen to yield olefinic halogenated compounds (e.g., acids and lactones) containing at least four halogen atoms per molecule is disclosed. The halogenation is purely thermal with preferred temperature ranges being selected as a function of the particular end product desired. Halogenated products of the process as well as ammonia and amine salts of the acids made by the process are useful as insecticides, plant grown control agents and defoliants. Particularly useful products are those olefinic polychlorinated derivatives of gamma-keto-pentanoic acid which contain at least four chlorine atoms per molecule such as, for example, 2,3,5,5,5pentachloro-4-keto pentenoic acid, its ammonium salt and its amine salts.
摘要翻译：公开了C4-C10饱和酮基单羧酸或其酸性衍生物与元素卤素的直接卤化，以产生每分子含有至少四个卤素原子的烯属卤代化合物（例如酸和内酯）。卤化是纯热的，优选的温度范围被选择为所需的特定最终产物的函数。该方法的卤代产物以及通过该方法制备的酸的氨和胺盐可用作杀虫剂，植物生长的控制剂和脱叶剂。特别有用的产品是每分子含有至少四个氯原子的γ-酮戊酸的烯烃多氯代衍生物，例如2,3,5,5,5-五氯-4-酮戊烯酸，其铵盐及其胺盐。

53. 发明授权

US3806521A Salicylate carbonate compounds 失效
标题翻译：碳酸亚乙酯化合物
公开(公告)号：US3806521A
公开(公告)日：1974-04-23
申请号：US20348471
申请日：1971-11-30
申请人： LIGGETT & MYERS INC
发明人： KALLIANOS A , MOLD J , SIMPSON M
IPC分类号： C07C69/90 , C07C65/00
CPC分类号： C07C69/90
摘要： THIS INVENTION RELATES TO NOVEL CARBONATE ANHYDRIDE ESTERS OF ACETYSALICYLIC ACID HAVING THE GENERAL FORMULA:

1-(CH3-COO-),2-(R-O-CO-O-CO-)BENZENE

WHEREIN R IS RADICAL SELECTED FROM THE GROUP CONSISTING OF: BRANCHED, SATURATED AND UNSATURATED, ALIPHATIC AND ALICYCLIC ALCOHOLS HAVING FROM 3 TO 30 CARBON ATOMS; STRAIGHT-CHAINED, SATURATED AND UNSATURATED, ALIPHATIC AND ALICYCLIC ALCOHOLS AND HAVING FROM 6-30 CARBON ATOMS; POLYHYDROXY COMPOUNDS; AND MIXTURES THEREOF.

54. 发明授权

US3600437A Substituted phenylalkanoic acids and derivatives thereof 失效
标题翻译：取代的苯甲酸及其衍生物
公开(公告)号：US3600437A
公开(公告)日：1971-08-17
申请号：US82875669
申请日：1969-05-28
申请人： LILLY CO ELI
发明人： MARSHALL WINSTON STANLEY
IPC分类号： C07C43/295 , C07C57/30 , C07C59/68 , C07C69/66 , C07C275/24 , C07D257/04 , C07C65/00 , C07C149/40
CPC分类号： C07D257/04 , C07C43/295 , C07C275/24 , C07C323/00 , Y10S514/916
摘要： NOVEL ALKANOIC ACIDS, SUBSTITUTED BY 3-PHENOXYPHENYL OR 3-PHENYLTHIOPHENYL GROUPS, AND THE ESTERS, AMIDES, AMINES, ALCOHOLS, ETHERS, TETRAZOLES, CARBAMATES, AND UREAS RELATED THERETO AS WELL AS NOVEL INTERMEDIATES USEFUL IN THE PREPARATION OF SUCH COMPOUNDS. THE COMPOUNDS OF THIS INVENTION ARE USEFUL AS ANTIINFLAMMATORY, ANALGESIC, AND ANTIPYRETIC AGENTS.

55. 发明授权

US3564042A Derivatives of acetic acid 失效
标题翻译：醋酸的衍生物
公开(公告)号：US3564042A
公开(公告)日：1971-02-16
申请号：US3564042D
申请日：1967-03-17
申请人： SANDOZ AG
发明人： GRIOT RUDOLF G
IPC分类号： C07C59/68 , C07C65/00 , C07C69/76
CPC分类号： C07C59/68
摘要： THE COMPOUNDS ARE OF THE CLASS OF A, A-BIS(P-CHLOROPHENOXY)-A-SUBSTITUTED ACETIC ACIDS AND ESTERS THEREOF WHICH ARE USEFUL AS HYPOCHOLESTEREMIC/HYPOLIPEMIC AGENTS.

56. 发明授权

US3057776A Schistosomiasis treatment 失效
标题翻译：血吸虫病治疗
公开(公告)号：US3057776A
公开(公告)日：1962-10-09
申请号：US80144459
申请日：1959-03-24
申请人： PARKE DAVIS & CO
发明人： SHORT FRANKLIN W , ELSLAGER EDWARD F
IPC分类号： A61K31/13 , C07C65/00 , C07C65/11 , C09B11/12 , C09B11/20
CPC分类号： C09B11/20 , A61K31/13 , C07C65/00 , C07C65/11 , C09B11/12
摘要： Orally administrable therapeutic compositions in dosage unit form comprise a pharmaceutical carrier and, as active ingredient, pararosaniline or a salt thereof with a mineral acid or with a p monobasic organic acid containing a single carboxyl or sulphonic acid group. Suitable salts are the hydrochloride (parafusehin), hydrobromide, hydroiodide, acetate, sulphate, palmitate, stearate, salicylate, hydroxynaphthoate and 2-hydroxy-6-naphthalene sulphonate, the compositions preferably containing from 50 to 500 mg. of pararosaniline per dosage unit, e.g. as tablets, powders, capsules, solutions, suspensions and enterically coated forms comprising conventional solid and liquid carriers, diluents, preservatives and flavouring agents.

57. 发明授权

US11351476B2 Method for chemical separation of cannabinoids 有权
公开(公告)号：US11351476B2
公开(公告)日：2022-06-07
申请号：US16781330
申请日：2020-02-04
申请人： AGRIFY CORPORATION
发明人： Alex Goodnough
IPC分类号： C07C65/00 , C07C51/00 , B01D11/00 , B01D11/04 , C07D311/80 , C07C65/17 , C07C51/573
摘要： A method for chemical separation of cannabinoids includes: (i) providing a starting organic solvent solution that contains a mixture of cannabinoid acids, (ii) using an aqueous basic solution to remove a portion of the cannabinoid acids from the mixture of cannabinoid acids in the starting organic solvent solution by converting the portion of the cannabinoid acids to cannabinoid carboxylate salts that solubilize in the an aqueous basic solution, (iii) separating the aqueous basic solution in (ii) from the starting organic solvent, (iv) combining the aqueous solution from (iii) with new organic solvent to produce a combined solution, (v) acidifying the combined solution to extract the cannabinoid acids from the aqueous solution to the organic solvent, (vi) separating the organic solvent of (v) from the aqueous solution, and (vii) evaporating the organic solvent of (vi) to leave product cannabinoid acids.

58. 发明授权

US11338222B2 Cannabis products modified by removing volatile organic compounds and adding volatile unsaturated hydrocarbons 有权
公开(公告)号：US11338222B2
公开(公告)日：2022-05-24
申请号：US17098539
申请日：2020-11-16
申请人： HIGH SIERRA TECHNOLOGIES, INC.
发明人： Vincent C. Lombardi
IPC分类号： C07C37/50 , C07C39/19 , C07C65/00 , C07B63/00 , B01D11/00 , B01D11/04 , B01D11/02 , A61P1/08 , A61K36/185 , C07C37/80 , C11B1/10 , C07C65/03 , C07D311/78
摘要： Purified and modified Cannabis products and methods for producing the same. The purified Cannabis product comprises substantially no volatile organic compounds while retaining Total Potential cannabinoid content. The modified Cannabis product comprises a purified Cannabis product modified by at least one added volatile unsaturated hydrocarbon. The modified Cannabis product is formed by extracting a volatile organic compound from a Cannabis raw material to form a purified Cannabis product, and then adding the at least one volatile unsaturated hydrocarbon to the purified Cannabis product to form the modified Cannabis product and cause an enhanced user experience during combustion and inhalation of the modified Cannabis product.

59. 发明授权

US09079875B2 Method for decarboxylating C—C cross-linking of carboxylic acids with carbon electrophiles 有权
标题翻译：羧酸与碳亲电体的C-C交联脱羧的方法
公开(公告)号：US09079875B2
公开(公告)日：2015-07-14
申请号：US11913626
申请日：2006-05-10
申请人： Lukas Goossen , Guojun Deng
发明人： Lukas Goossen , Guojun Deng
IPC分类号： C07C63/00 , C07C65/00 , C07C61/00 , C07C61/08 , C07C19/00 , C07C2/66 , C07C5/09 , C07C15/40 , C07C2/26 , C07D333/08 , B01J31/18 , B01J31/22 , B01J31/24 , B01J31/26 , C07B37/04 , C07C1/26 , C07C17/263 , C07C17/266 , C07C41/30 , C07C45/68 , C07C45/72 , C07C201/12 , C07C209/68 , C07C231/12 , C07C253/30 , C07C315/04 , C07C319/20 , B01J27/122 , B01J27/232
CPC分类号： C07D333/08 , B01J27/122 , B01J27/232 , B01J31/1815 , B01J31/183 , B01J31/2234 , B01J31/2404 , B01J31/26 , B01J2231/4205 , B01J2531/0241 , B01J2531/16 , B01J2531/17 , B01J2531/824 , C07B37/04 , C07C1/26 , C07C17/263 , C07C17/2637 , C07C17/266 , C07C41/30 , C07C45/68 , C07C45/72 , C07C201/12 , C07C209/68 , C07C231/12 , C07C253/30 , C07C315/04 , C07C319/20 , C07C2527/122 , C07C2531/24 , C07C2531/28 , C07C2531/30 , C07C2603/26 , C07C15/52 , C07C25/18 , C07C25/24 , C07C49/782 , C07C47/546 , C07C49/84 , C07C317/14 , C07C211/55 , C07C233/07 , C07C255/64 , C07C323/09 , C07C205/06 , C07C205/11 , C07C205/35 , C07C205/44 , C07C205/45 , C07C205/57 , C07C43/205
摘要： The invention relates to a method for decarboxylating C—C bond formation by reacting carboxylic salts with carbon electrophiles in the presence of transition metal compounds as catalysts. The method represents a decarboxylating C—C bond formation of carboxylic acid salts with carbon electrophiles, wherein the catalyst contains two transition metals and/or transition metal compounds, from which one is present, preferably, in the oxidation step, which are different from each other by one unit, and catalyzes a radical decarboxylation which is absorbed during the second oxidation steps, which are different from each other by two units and catalyzes the two electron processes of a C—C bond formation reaction.
摘要翻译：本发明涉及通过在过渡金属化合物作为催化剂存在下使羧酸与碳亲电体反应来脱羧C-C键形成的方法。该方法表示与碳亲电体形成羧酸盐的羧基C-C键，其中催化剂含有两种过渡金属和/或过渡金属化合物，优选在氧化步骤中存在一种不同于催化自由基脱羧，其在第二氧化步骤期间被吸收，它们通过两个单元彼此不同并且催化C-C键形成反应的两个电子过程。

60. 发明授权

US08669209B2 Process for preparing soluble granules of salts of pyridine containing carboxylic acids 有权
标题翻译：制备含有羧酸的吡啶盐的可溶性颗粒的方法
公开(公告)号：US08669209B2
公开(公告)日：2014-03-11
申请号：US12951100
申请日：2010-11-22
申请人： Franklin N. Keeney , Neil A. Foster , Martin C. Logan , Maria G. Perry
发明人： Franklin N. Keeney , Neil A. Foster , Martin C. Logan , Maria G. Perry
IPC分类号： A01N43/40 , C07D211/72 , C07D211/84 , C07D213/68 , C07D213/72 , C07D213/78 , C07C61/08 , C07C59/56 , C07C59/88 , C07C65/00 , C07C229/00 , C07C62/00
CPC分类号： A01N43/40 , A01N25/12 , A01N2300/00
摘要： Soluble granule formulations of amine salts of pyridine containing carboxylic acids with improved handling properties are provided by an improved process in which the pyridine containing carboxylic acid is partially neutralized with an amine.
摘要翻译：通过改进的方法提供含有羧酸吡啶的胺盐的可溶性颗粒剂，其中含吡啶的羧酸被胺部分中和。

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