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51. 发明申请

US20010012915A1 Ferromagnetic foreign body detection using magnetics 失效
标题翻译：铁磁异物检测使用磁性
公开(公告)号：US20010012915A1
公开(公告)日：2001-08-09
申请号：US09741774
申请日：2000-12-15
发明人： William F. Avrin , Peter V. Czipott , R. Kemp Massengill , Sankaran Kumar
IPC分类号： A61B005/05
CPC分类号： A61B5/055 , A61B5/04005 , A61B5/05 , A61B5/416 , A61B5/4244 , G01R33/16 , G01V3/08
摘要： A probe instrument using room-temperature sensor(s) that can measure magnetic susceptibilities variations. The instrument includes room temperature magnetic sensors, and detects the sample, that is the tissue response to an applied field coil. The sensors that can be used include magnetoresistive, fluxgate and magnetoinductive sensors. The applied field coil dimensions are chosen so that the applied field is optimized for maximum response from the item of interest while minimizing the effects due to the overlying tissue and at the same time not unduly increasing the sensitivity of the instrument to adjacent organs. To minimize noise introduced in the sensor due to fluctuations in the applied field, the applied field is canceled at the position of the sensor. To overcome variations in the sensor output due to fluctuations in the applied field, change in the ambient temperature and mechanical relaxation of the instrument, the detector assembly is oscillated while the examined patient remains stationary.
摘要翻译：使用可测量磁化率变化的室温传感器的探头仪器。该仪器包括室温磁传感器，并检测样品，即对施加的场线圈的组织响应。可以使用的传感器包括磁阻，磁通门和磁感应传感器。选择施加的磁场线圈尺寸，使得所施加的磁场被优化用于来自感兴趣项目的最大响应，同时使由于上覆组织引起的影响最小化，并且同时不会不适当地增加仪器对相邻器官的灵敏度。为了最小化由于施加场的波动引起的传感器噪声，施加的场在传感器的位置被取消。为了克服由于施加场的波动导致的传感器输出的变化，环境温度的变化和仪器的机械松弛，检测器组件在被检查的患者保持静止时振荡。

52. 发明授权

US12016696B2 Device for the qualitative evaluation of human organs 有权
公开(公告)号：US12016696B2
公开(公告)日：2024-06-25
申请号：US17467215
申请日：2021-09-05
申请人： SMICES
发明人： Clément Labiche
IPC分类号： A61B5/00 , A61B1/04 , A61B1/06 , G06T7/00 , G06T7/40 , G06T7/90 , G16H30/40 , G16H50/20
CPC分类号： A61B5/4244 , A61B1/04 , G06T7/0012 , G06T7/40 , G06T7/90 , G16H30/40 , G16H50/20 , A61B1/0661 , G06T2207/10068 , G06T2207/20081 , G06T2207/30056 , G06T2207/30168
摘要： This method for qualitatively evaluating human livers comprises:

a step (301) of computing normalized histograms of colour channels from a portion of a photograph of a liver;
a step (304) of loading coefficients obtained at the end of a training phase;
a step (305) of extracting from the histograms values corresponding to variables retained at the end of the training phase;
a step (306) of computing a linear combination of the extracted values weighted with the loaded coefficients; and
a step (308, 309) of displaying information representative of the result of the computation of the linear combination.

53. 发明公开

US20230338085A1 RADIO FREQUENCY ABLATION SYSTEMS 审中-公开
公开(公告)号：US20230338085A1
公开(公告)日：2023-10-26
申请号：US18215418
申请日：2023-06-28
申请人： Medical Engineering Innovations, Inc.
发明人： Steven Charles Southwell , Joshua Cook , Tim Holzmann , David Strait , Richard Schmidt
IPC分类号： A61B18/18 , A61B18/12 , A61B5/00
CPC分类号： A61B18/18 , A61B18/1206 , A61B5/4244 , A61B2018/00577
摘要： The present invention relates to systems for use for radio frequency ablation. The systems can include one or more of an ablation tool, power source for use with the ablation tool and a backstop for use in conjunction with the ablation tool during surgical procedures. Preferred ablation tools comprise a series of three or more blade-shaped electrodes disposed in a linear, curved, curvilinear or circular array. The backstops are useful for reducing direct physical and thermal heat transfer injuries to the patient or surgeon during procedures using radiofrequency (RF) ablation devices.

54. 发明授权

US11730374B1 Radio frequency applicator for a thermoacoustic imaging system 有权
公开(公告)号：US11730374B1
公开(公告)日：2023-08-22
申请号：US17865034
申请日：2022-07-14
申请人： ENDRA Life Sciences Inc.
发明人： Jordan Sengenberger , Christopher Nelson Davis , Christopher Bull , Charlton Chen , Jang Hwan Cho , Idan Steinberg , Michael M. Thornton
IPC分类号： A61B5/00 , A61B18/04 , A61B8/08 , A61B5/0507 , A61B8/00 , A61B5/05
CPC分类号： A61B5/0093 , A61B18/04 , A61B5/0095 , A61B5/05 , A61B5/0507 , A61B5/4244 , A61B5/489 , A61B8/00 , A61B8/5261
摘要： A radio frequency applicator for a thermoacoustic imaging system is disclosed. The applicator includes, a waveguide with an internal radio frequency source, wherein the waveguide has an opening, an electromagnetic matching layer coupled to the waveguide and proximate to the opening, and an acoustic absorbing layer that is coupled to the matching layer.

55. 发明授权

US10869606B2 Method and apparatus for human health evaluation 有权
公开(公告)号：US10869606B2
公开(公告)日：2020-12-22
申请号：US15588579
申请日：2017-05-05
申请人： Jiangsu Huaben Health Life Science and Technology Co., Ltd.
发明人： Ben Jun Wu
IPC分类号： A61B5/0205 , A61B5/024 , G16H50/20 , A61B5/022 , G16H40/63 , G16H50/30 , A61B5/08 , A61B5/20 , A61B5/00 , A61B5/021
CPC分类号： A61B5/0205 , A61B5/022 , A61B5/02438 , A61B5/08 , A61B5/201 , A61B5/4064 , A61B5/416 , A61B5/4244 , A61B5/4854 , A61B5/6824 , A61B5/7267 , A61B5/7275 , G16H40/63 , G16H50/20 , G16H50/30 , A61B5/021 , A61B5/024
摘要： Techniques and examples pertaining to evaluating a health condition of an aspect of a patient are described. A method for evaluating the health condition of the aspect of the patient may involve obtaining successive measurement readings of a vital sign concurrently from both a left arm and a right arm of the patient for a plurality of times. The method may also involve calculating a characteristic value based on the measurement readings. The method may also involve designating a health indicator based on the characteristic value and a standard value associated with the aspect of the patient, such that the health indicator serves as an indication of the health condition of the aspect of the patient. The aspect of the patient may be a body organ of the patient. The method may further involve diagnosing the patient based on the health indicator.

56. 发明授权

US10610302B2 Liver disease assessment in medical imaging 有权
公开(公告)号：US10610302B2
公开(公告)日：2020-04-07
申请号：US15641514
申请日：2017-07-05
申请人： Siemens Healthcare GmbH
发明人： Dorin Comaniciu , Thomas Pheiffer , David Liu , Ankur Kapoor , Tommaso Mansi
IPC分类号： A61B34/10 , G06F19/00 , G06T11/00 , A61B18/00 , A61B5/055 , A61B5/00 , A61B8/08 , G16H50/30 , G16H50/50 , A61B18/12 , A61B18/02 , A61N7/00 , G06T7/00 , G16H30/40 , G16H40/63 , G06K9/62 , A61B6/03 , G06T7/11 , A61N5/10 , A61B5/026
CPC分类号： A61B34/10 , A61B5/0035 , A61B5/055 , A61B5/4244 , A61B8/485 , A61B18/00 , A61B18/02 , A61B18/12 , A61N7/00 , G06F19/321 , G06K9/6289 , G06T7/0012 , G06T11/003 , G16H30/40 , G16H40/63 , G16H50/30 , G16H50/50 , A61B5/0263 , A61B6/03 , A61B8/5223 , A61B2018/00529 , A61B2018/00535 , A61B2018/00577 , A61B2034/104 , A61B2034/105 , A61N5/1002 , A61N5/103 , G06K9/6256 , G06K9/6267 , G06K2209/051 , G06T7/11 , G06T2207/10081 , G06T2207/10088 , G06T2207/30024 , G06T2207/30056 , G06T2207/30096 , G06T2210/41
摘要： For liver modeling from medical scan data, multiple modalities of imaging are used. By using multiple modalities of imaging in combination with generative modeling, a more comprehensive and informed assessment may be performed. The generative modeling may allow feedback of effects of proposed therapy on function of the liver. This feedback is used to update the liver function information based on the imaging. Based on the computerized modeling with information from various imaging modes, an output based on more comprehensive information and patient personalized modeling and feedback may be provided to assist the physician.

57. 发明申请

US20180317778A1 Method And Apparatus For Human Health Evaluation 审中-公开
公开(公告)号：US20180317778A1
公开(公告)日：2018-11-08
申请号：US15588579
申请日：2017-05-05
申请人： Jiangsu Huaben Health Life Science and Technology Co., Ltd.
发明人： Ben Jun Wu
IPC分类号： A61B5/0205 , A61B5/00 , A61B5/08 , A61B5/20
CPC分类号： A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/08 , A61B5/201 , A61B5/4064 , A61B5/416 , A61B5/4244 , A61B5/4854 , A61B5/6824 , A61B5/7267 , A61B5/7275
摘要： Techniques and examples pertaining to evaluating a health condition of an aspect of a patient are described. A method for evaluating the health condition of the aspect of the patient may involve obtaining successive measurement readings of a vital sign concurrently from both a left arm and a right arm of the patient for a plurality of times. The method may also involve calculating a characteristic value based on the measurement readings. The method may also involve designating a health indicator based on the characteristic value and a standard value associated with the aspect of the patient, such that the health indicator serves as an indication of the health condition of the aspect of the patient. The aspect of the patient may be a body organ of the patient. The method may further involve diagnosing the patient based on the health indicator.

58. 发明申请

US20180267016A1 PURE NON-INVASIVE METHOD FOR IDENTIFICATION OF ORGAN DISEASES OR IMPAIRED ORGAN FUNCTION BY INVESTIGATION OF MARKER SUBSTANCES IN EXHALED AIR STIMULATED BY INHALED MARKER SUBSTANCES 审中-公开
公开(公告)号：US20180267016A1
公开(公告)日：2018-09-20
申请号：US15760211
申请日：2016-09-14
申请人： FREIE UNIVERSITÄT BERLIN
发明人： Theodore VON HAIMBERGER , Anja HEYNE , Karsten HEYNE
IPC分类号： G01N33/497 , A61B5/08 , G16H50/30 , G16H50/20 , A61B5/00 , G01N33/58
CPC分类号： G01N33/497 , A61B5/082 , A61B5/4244 , G01N33/58 , G06F19/36 , G16H50/20 , G16H50/30
摘要： The disclosure relates to a method for providing original data that can be used for subsequently determining the function of an organ of a living organism or for subsequently diagnosing a disease or a severity of a disease of an organ of a living organism. This method is characterized by several steps, one of which is administering a marker substance to a living organism by inhalation, wherein the marker substance has a vapor pressure above 0.01 mmHg at 37° C. In other method steps, the concentration of this marker substance in exhaled air is determined at at least two different time points. Then, a difference in marker substance concentration is calculated.

59. 发明授权

US10076264B2 System and method for quantitative magnetic resonance (MR) analysis using T1 mapping 有权
公开(公告)号：US10076264B2
公开(公告)日：2018-09-18
申请号：US15169208
申请日：2016-05-31
申请人： Case Western Reserve University
发明人： Susann Brady-Kalnay , Vikas Gulani , Mark Griswold
IPC分类号： A61B5/055 , G01R33/56 , A61B5/00 , A61K49/10 , G08C23/06 , G01R33/50
CPC分类号： A61B5/055 , A61B5/0073 , A61B5/4244 , A61B5/742 , A61B2576/00 , A61B2576/026 , A61K49/108 , G01R33/50 , G01R33/5601 , G01R33/5602 , G08C23/06
摘要： Example apparatus and methods concern determining whether a target material appears in a region experiencing nuclear magnetic resonance (NMR). One method acquires a baseline value for a magnetic resonance parameter (MRP) while the region is not exposed to a molecular imaging agent that affects the MRP and acquires a series of quantitative values for the MRP while the sample is influenced by a molecular imaging agent. Quantitative values may be acquired during a clinically relevant time period (e.g., 60 minutes) during which the change in the MRP (e.g., T1) caused by the molecular imaging agent is at least 90% of the peak change caused by the molecular imaging agent. The molecular imaging agent may be SBK2 and may produce a desired change in T1 for at least thirty minutes in glioblastoma.

60. 发明申请

US20180220949A1 APPARATUS AND METHOD FOR IN-VIVO FAT AND IRON CONTENT MEASUREMENT 审中-公开
公开(公告)号：US20180220949A1
公开(公告)日：2018-08-09
申请号：US15868996
申请日：2018-01-11
申请人： Pablo Jose Prado
发明人： Pablo Jose Prado
IPC分类号： A61B5/00 , G01R33/46 , A61B5/055
CPC分类号： A61B5/4244 , A61B5/055 , A61B5/0555 , A61B5/4872 , G01R33/3802 , G01R33/3808 , G01R33/383 , G01R33/46 , G01R33/4828
摘要： An apparatus for measuring liver fat content and/or iron content non-invasively in vivo using unilateral NMR technology is disclosed. The apparatus comprises a unilateral NMR probe positioned against or in the proximity of the body. The probe generates static and RF magnetic fields to measure NMR signals at selected depths into the body. The apparatus further comprises a unilateral magnet and a unilateral antenna placed between a magnet and the body or around the magnet. The unilateral antenna is used to attain NMR signals. The measurement of NMR signals at a single position with a single frequency determines fat content on a specific volume inside the liver. The measurement of NMR signals at a single position with two or more frequencies determines iron content on a specific volume inside the liver.

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